23 results about "Beta-glucan" patented technology

The invention relates to a composition for treating large yellow croaker pyramidoniasis as well as a preparation method and application thereof, and belongs to the technical field of aquaculture. The composition comprises the following components: curcumin, bile acid, beta glucan, bacillus subtilis freeze-dried powder, marine red yeast freeze-dried powder, vitamin C, vitamin E and ethylicin. When the feed additive is added into basal feed to feed large yellow croakers infected with the trypanosomiasis, the death rate of sick fishes can be effectively reduced, the polypide loading capacity is remarkably reduced, and pathological injuries of livers and spleens of the large yellow croakers are relieved. In addition, the composition can also improve the non-specific immunity of the fish body, improve the liver function, enhance the antioxidant capacity of the liver, and improve the lipase activity of the intestinal tract at the same time. Therefore, the composition can be used as a medicine or a feed additive for treating the large yellow croaker pyramidoniasis, has the advantages of small dosage and remarkable effect, and provides a new technical approach for solving the problem that the current large yellow croaker pyramidoniasis lacks an effective prevention and control means.

A process for using bacterial or fungal metalloprotease and trypsin to solve problems associated with conventional protease extraction techniques by dramatically reducing temperature, incubation time and proteolysis during protease extraction. The present disclosure relates to a protease treatment for increasing yield from plant or other material by extracting nutrients from the fibrous waste portion of milled plant material while preserving the nutritional and functional qualities of the extracted material for use as a food product. The process preserves the quality of the extracted material, including beta glucan and protein, by utilizing low temperatures and minimal protease activity and digestion time during extraction.

A method of managing a disorder associated with a circadian rhythm disorder in a subject by administering to the subject an effective amount of a beta glucan oligosaccharide and / or an arabinose oligosaccharide. More specifically, the management includes treating a symptom associated with a circadian rhythm disorder, primary preventing a symptom associated with a circadian rhythm disorder, secondary preventing a symptom associated with a circadian rhythm disorder, and / or delaying progression of a symptom associated with a circadian rhythm disorder. The symptoms to be managed include symptoms related to sleep, symptoms related to emotion, symptoms related to cognitive function decline and neurocognitive decline, and the like. In particular methods herein, the risk of developing a symptom associated with a circadian rhythm disorder in the subject is assessed prior to administration of the beta glucan oligosaccharide and / or arabinose oligosaccharide. Also provided are medicaments, nutritional formulations, nutritional supplements and pharmaceutical compositions comprising an effective amount of beta glucan oligosaccharides and / or arabinose oligosaccharides for use in such treatment, prevention and delay.

A cosmetic composition is disclosed for applying to skin. The composition includes a liquid and dispersed in the liquid: any amount or form of fucoidan, any amount or form of beta glucan; and any amount of a marine extract. When the cosmetic composition is applied to the skin, the appearance of the skin is improved.

The invention discloses a buccal product and a preparation method thereof, the buccal product comprises a first embedding material, a filler and an antioxidant, the first embedding material comprises an active substance and a first embedding layer, the first embedding layer is used for coating the active substance to isolate the active substance from the outside of the first embedding layer, and the first embedding layer comprises beta-glucan. The active substance is embedded through the first embedding layer containing beta glucan so as to isolate the active substance from being in contact with external air, the risk that the active substance is oxidized is reduced through physical barrier protection, meanwhile, the oxidation of the buccal product is further reduced by adding the antioxidant and utilizing the characteristics of the antioxidant, and the stability of the buccal product is improved. And the oxidation speed of active substances can be effectively delayed due to oxidation resistance of double different mechanisms.

The invention discloses a plant immune resistance inducer based on yeast beta glucan and melatonin and application, and belongs to the technical field of plant protection. The invention provides a plant immune resistance inducer based on yeast beta glucan and melatonin, the active ingredients of the plant immune resistance inducer are composed of the yeast beta glucan and the melatonin, and the mass ratio of the yeast beta glucan to the melatonin is (300-800): (1-20). It is verified that when the yeast beta glucan and melatonin are combined to serve as the plant immunity resistance inducer, the synergistic interaction effect is achieved in the aspects of inducing plant immunity and promoting plant growth activity.

The invention belongs to the technical field of biological pharmacy, and particularly relates to an intestinal targeting type urolithin A water-soluble delivery system as well as a preparation method and application thereof. The intestinal targeting type urolithin A water-soluble delivery system is characterized in that an aqueous solution of zinc nitrate-polyvinylpyrrolidone and a methanol solution of 2-methylimidazole-urolithin A are subjected to ultrasonic treatment respectively and then are mixed and stirred, and ZIF-8 loaded with urolithin A is obtained; the preparation method comprises the following steps: dropwise adding a carboxymethyl beta glucan solution into a ZIF-8 dispersion liquid loaded with urolithin A, adding CaCl2, and coating the surface with a methyl beta glucan modification layer. According to the protection-targeting-synergism integrated delivery system constructed by the invention, the problems of low UA stability, poor targeting property, insufficient bioavailability and the like are solved.

The invention relates to a preparation method and application of novel egg white protein muscle building powder, and provides high-quality nutrition support for improving muscle quality. The method takes fresh egg white as a raw material; a finished product is prepared through the steps of egg white separation after eggshell disinfection, ultrasonic-shearing synergetic flocculation removal, yeast beta glucan-polyphenol composite microsphere live protection system addition, acid-dynamic high-pressure microjet low-temperature pretreatment, compound protease enzymolysis, ultrafiltration impurity removal, gradient pH membrane separation and purification, low-temperature vacuum spray drying and the like. The composite microspheres are adopted to replace chemical protecting groups, and the whole-course low-temperature processing technology is combined, so that the activity of branched chain amino acid is effectively maintained. The protein powder can prolong the exercise exhaustion time of mice with muscle injury, improve the muscle repair efficiency, and realize the dual functions of muscle-building nutrition and oxidation resistance. The product adapts to various food systems, and can be widely applied to the fields of sports nutrition and food for special medical purposes.

The present invention relates to antibodies, or antigen-binding fragments thereof, that have binding specificity to β-glucans. Also described are the production of such monoclonal antibodies, and nucleic acids encoding such antibodies.

The invention provides mouthwash for preventing and treating oral ulcer and a preparation method thereof, and belongs to the technical field of oral care. The mouthwash is prepared from the following components in percentage by weight: 0.01 to 0.5 percent of dipotassium glycyrrhizinate, 0.05 to 0.5 percent of beta glucan, 0.01 to 0.3 percent of hyaluronic acid, 0.05 to 1 percent of honeysuckle flower extract, 0.5 to 5 percent of a solubilizer, 1.001 to 10.1 percent of a sweetening agent, 2 to 20 percent of a humectant, 0.01 to 0.5 percent of a chelating agent, 0.1 to 0.6 percent of a preservative, 0.01 to 0.5 percent of a flavoring agent, 1 to 10 percent of a solvent, 0.01 to 0.2 percent of a coloring agent and the balance of water. According to the mouthwash disclosed by the invention, all the components are combined together, the synergistic effect of '1 + 1gt, 2' can be exerted instead of simple effect addition, the oral ulcer can be effectively prevented and treated, and the effect is far better than that of existing commercially available products.

This invention belongs to the field of modified protein technology, and provides a shiitake mushroom protein crude extract-β-glucan complex and its application. The shiitake mushroom variety includes Shenxiang 1513, and the origin of Shenxiang 1513 includes Hubei or Zhejiang. The β-glucan includes at least one of barley β-glucan, oat β-glucan, and yeast β-glucan. This invention found that, compared with shiitake mushroom protein crude extract alone, the shiitake mushroom protein crude extract-β-glucan complex significantly increased the production of short-chain fatty acids and promoted the proliferation of beneficial bacteria. Simultaneously, this invention, through microbiome and metabolomics analysis, identified Bacillus phylum as a key positive regulator and confirmed its association with the upregulation of metabolic pathways such as purines, lipids, bile acids, and amino acids. These findings indicate that the shiitake mushroom protein crude extract-β-glucan complex of this invention has superior prebiotic potential, providing a theoretical basis for the development of functional food ingredients.

Methods and solutions are disclosed for the quantification of mixed-linkage beta-glucan in plant biomass samples. Improved alkaline pretreatment, enzymatic hydrolysis, and glucose measurement parameters are provided that increase the accuracy, precision, and sensitivity of mixed-linkage beta-glucan assays.

The application relates to a preparation method of a beta glucan supramolecular polymer, the beta glucan supramolecular polymer and application, and belongs to the technical field of supramolecular polymer preparation. The preparation method of the beta glucan supramolecular polymer comprises the following steps: introducing a schizophyllum commune liquid into a culture medium, wherein the culture medium comprises an active substance and a culture medium substrate, the mass ratio of the schizophyllum commune liquid to the active substance is 1-10:1; and the culture medium is fermented at 27-30 DEG C for 90-100 h to obtain the beta glucan supramolecular polymer loaded with the active substance. The physical wrapping and chemical cross-linking methods are avoided, the residue problem of toxic and harmful reagents is avoided, and the loading rate is effectively improved.

The present application belongs to the technical field of nutritional health food, and particularly relates to a composition for repairing oral mucosa and a preparation method and application thereof. The composition comprises, by weight of the composition: 2%-80% of yeast beta glucan, 0.5%-50% of lactobacillus salivarius powder, 0.5%-50% of lactobacillus acidophilus powder, and 0.5%-50% of paracasei lactobacillus powder. The composition for repairing oral mucosa and the auxiliary materials are further prepared into a functional food in the form of tablets, liquids, soft candies or powders. In the functional food, the composition as the main component plays a role in repairing and preventing damage to the oral mucosa. Meanwhile, the composition and the auxiliary materials are dissolved under the action of oral saliva enzymes, thereby fully contacting the oral mucosa and pathogens and emitting a sweet and sour taste, so as to bring a pleasant sensory experience to the oral cavity.

The invention provides a sodium-reduced tricholoma matsutake seasoning as well as a preparation method and application thereof, and belongs to the field of food processing. Through directional enzymolysis and microcapsule embedding ring release technologies, the tricholoma matsutake and the mushrooms are subjected to enzymolysis, the mushroom flavor and other umami components in the tricholoma matsutake and the mushrooms are released, beta glucan is obtained while the overall flavor is improved, fruit and vegetable components rich in colloid are subjected to enzymolysis, pectin and sweetening flavor components in fruits and vegetables are released, and the taste of the tricholoma matsutake and the mushrooms is improved. A natural embedding wall material is obtained, so that the problem of high-temperature flavor loss of the traditional mushroom seasoning is solved; and secondly, potassium element extraction and enrichment are performed on fruit and vegetable raw materials rich in potassium, and the salty taste is enhanced by utilizing components such as organic acid and saccharides naturally contained in fruits and vegetables, so that part of edible salt is replaced, and the sodium-reduced tricholoma matsutake seasoning which is rich in mushroom flavor and is reduced in sodium but not reduced in salty taste is obtained.

This invention belongs to the field of aquatic food technology and relates to the preparation technology of functional fish paste. The preparation method of the fish paste product of this invention includes: dissolving 2-4 parts of barley β-glucan, 1-2 parts of astaxanthin, 0.5-0.7 parts of Tween-80, and 20-25 parts of milk powder in 100 parts of water, stirring evenly, homogenizing, and then spray drying; adding 0.2 w / w% chitosan solution to the marine fish paste at a weight ratio of 8-10:1, mixing thoroughly, heating to mature, and cooling to 60-65°C; thoroughly mixing the results of the first two steps, and continuing to cool to below 55°C to form a gel, thus obtaining the final product. The fish paste product obtained by this invention has good antioxidant and anti-diarrheal effects, improving the value of the fish paste and showing good application prospects. This invention discovers that astaxanthin and barley β-glucan have a synergistic effect in antioxidant and anti-diarrheal aspects, improving the application value of barley β-glucan.

The present invention relates to a pet food supplement composition comprising: a source of resistant starch; a source of beta glucan; a probiotic; L-carnitine; and alpha lipoic acid. The pet food supplement composition can be used to promote weight loss or in the treatment of obesity.

The invention relates to the technical field of functional food, and particularly discloses a gastrodia elata-edible mushroom synergistic interaction-based intelligence-promoting and nerve-soothing mushroom soup formula which comprises seven raw materials including morchella esculenta (3-5 cm), pleurotus citrinopileatus (the umbrella diameter is 4-7 cm), pleurotus geesteranus (pileus is 2-4 cm / stem is smaller than or equal to 1 cm), gastrodia elata (2 cm thick slices), velvet antler mushrooms (4-5 cm segments), shiitake mushrooms (the umbrella diameter is 4-6 cm) and bolete (the slice thickness is 0.5-1 mm). The gastrodin-beta glucan compound is formed and a neurotransmitter dual-channel regulation mechanism is constructed by setting dynamic proportion conservation of raw materials to maintain size-activity matching, combining gradient superfine grinding with cryogenic wall breaking to directionally release active ingredients and activating a pleated channel through enzyme-ultrasonic coupling, so that the efficacy stability and brain targeting are remarkably improved, and the application prospect is wide. The composition is suitable for improving cognition and sleep functions.

The invention belongs to the technical field of biological materials, and provides a construction method and application of a nucleic acid transporter based on yeast beta glucan nanoparticles, beta glucan from yeast is cross-linked with 1.8 k PEI through carboxymethylation modification to prepare CMG-PEI NP to load nucleic acid, the nucleic acid transporter is applied to RNA transport, and a new way and means are provided for RNA transport. According to the invention, the structures of the CMG-PEINP and related components are evaluated, manninotriose is used for further wrapping the CMG-PEINP, a cell model is established, and the RNA transport efficiency of the CMG-PEINP transporter is evaluated. Results show that CMG-PEINP and nucleic acid can form a compound with a compact structure, the particle size meets the drug delivery requirement, and when the mass ratio of CMG-PEINP to eGFP mRNA is 48: 1, the transfection efficiency is the highest.

The present application provides a Ganoderma lucidum fermentation lysate, a preparation method thereof and application thereof in preparing cosmetics. The preparation method of the Ganoderma lucidum fermentation lysate comprises the steps of inducing fermentation, catalytic degradation, membrane filtration, spray drying and the like. The present application can prepare the Ganoderma lucidum fermentation lysate in an environmentally friendly, economical and efficient manner through inducing endogenous enzyme and metal ion catalytic regulation. The Ganoderma lucidum fermentation lysate prepared has a Ganoderma lucidum polysaccharide content of more than 18%, and the content of beta glucan in the Ganoderma lucidum polysaccharide is greater than 5%. The present application is proved by experiments that the Ganoderma lucidum fermentation lysate has good antioxidant activity and anti-aging effect, and has a broad market application prospect in the field of anti-aging cosmetics.

The invention discloses a composite nutritional food composition capable of enhancing an immune function and a preparation process, and belongs to the field of functional foods. The composition comprises two key modified components, namely a curcumin-beta-cyclodextrin inclusion compound and sulfated low-molecular fucoidin, and rhizoma curcumae longae, yeast beta glucan, zinc gluconate, a cordyceps militaris extract, ganoderma lucidum spore powder, polygonatum polysaccharide, an oyster extracting solution, plant lactobacillus and lactobacillus acidophilus are matched. The preparation process comprises the following steps: mixing the solid components except the probiotics; drying and granulating the liquid extracting solution, and mixing with the solid; and adding the probiotic powder and the auxiliary materials at low temperature, and uniformly mixing to finally prepare a capsule dosage form. Through molecular modification and scientific compounding of core active components, the bioavailability of insoluble components and the immunocompetence of natural polysaccharides are remarkably improved, all the components have a synergistic effect, the organism immune function is safely and effectively enhanced from multiple ways and multiple targets, and the product stability is good.

The disclosure relates to a fiber blend for a health benefiting nutrition formulation, comprising: a resistant starch obtained from one or more sources selected from the group consisting of green banana resistant starch, maize or corn resistant starch, and potato resistant starch, the resistant starch having a resistant starch weight; an oat beta glucan having a beta glucan weight; and a maize or corn resistant dextrin having a resistant dextrin weight. The ratio of [the resistant starch weight]:[the beta glucan weight]:[the resistant dextrin weight]=1:0.15-4:0.15-4.

The application provides an exosome composition for reducing side effects of chemotherapy treatment and a preparation method thereof, and belongs to the technical field of medicines. Methotrexate, vinblastine and daunorubicin are prepared into a co-crystal, loaded on UiO-66-NH2 connected with RGD, loaded on exosomes, and embedded in an acrylic acid, traditional Chinese medicine polysaccharide and pullulan compound to obtain a sustained-release high half-life exosome system, which is uniformly mixed with D-ribose, yeast-beta glucan and glutathione to obtain the exosome composition for reducing side effects of chemotherapy treatment. The traditional Chinese medicine polysaccharide is traditional Chinese medicine polysaccharide obtained by boiling water extraction and ethanol precipitation of radix codonopsis, angelica, polygonatum sibiricum and dendrobium officinale. The exosome composition for reducing side effects of chemotherapy treatment is prepared, drug resistance of tumor cells is reduced, drug efficacy is improved, side reactions after chemotherapy are reduced, the effect of targeted slow release of drugs is achieved, and the exosome composition has a wide application prospect.