14 results about "Beta-glucan" patented technology

The invention belongs to the technical field of biological pharmacy, and particularly relates to an intestinal targeting type urolithin A water-soluble delivery system as well as a preparation method and application thereof. The intestinal targeting type urolithin A water-soluble delivery system is characterized in that an aqueous solution of zinc nitrate-polyvinylpyrrolidone and a methanol solution of 2-methylimidazole-urolithin A are subjected to ultrasonic treatment respectively and then are mixed and stirred, and ZIF-8 loaded with urolithin A is obtained; the preparation method comprises the following steps: dropwise adding a carboxymethyl beta glucan solution into a ZIF-8 dispersion liquid loaded with urolithin A, adding CaCl2, and coating the surface with a methyl beta glucan modification layer. According to the protection-targeting-synergism integrated delivery system constructed by the invention, the problems of low UA stability, poor targeting property, insufficient bioavailability and the like are solved.

The invention relates to a preparation method and application of novel egg white protein muscle building powder, and provides high-quality nutrition support for improving muscle quality. The method takes fresh egg white as a raw material; a finished product is prepared through the steps of egg white separation after eggshell disinfection, ultrasonic-shearing synergetic flocculation removal, yeast beta glucan-polyphenol composite microsphere live protection system addition, acid-dynamic high-pressure microjet low-temperature pretreatment, compound protease enzymolysis, ultrafiltration impurity removal, gradient pH membrane separation and purification, low-temperature vacuum spray drying and the like. The composite microspheres are adopted to replace chemical protecting groups, and the whole-course low-temperature processing technology is combined, so that the activity of branched chain amino acid is effectively maintained. The protein powder can prolong the exercise exhaustion time of mice with muscle injury, improve the muscle repair efficiency, and realize the dual functions of muscle-building nutrition and oxidation resistance. The product adapts to various food systems, and can be widely applied to the fields of sports nutrition and food for special medical purposes.

The present invention relates to antibodies, or antigen-binding fragments thereof, that have binding specificity to β-glucans. Also described are the production of such monoclonal antibodies, and nucleic acids encoding such antibodies.

This invention belongs to the field of modified protein technology, and provides a shiitake mushroom protein crude extract-β-glucan complex and its application. The shiitake mushroom variety includes Shenxiang 1513, and the origin of Shenxiang 1513 includes Hubei or Zhejiang. The β-glucan includes at least one of barley β-glucan, oat β-glucan, and yeast β-glucan. This invention found that, compared with shiitake mushroom protein crude extract alone, the shiitake mushroom protein crude extract-β-glucan complex significantly increased the production of short-chain fatty acids and promoted the proliferation of beneficial bacteria. Simultaneously, this invention, through microbiome and metabolomics analysis, identified Bacillus phylum as a key positive regulator and confirmed its association with the upregulation of metabolic pathways such as purines, lipids, bile acids, and amino acids. These findings indicate that the shiitake mushroom protein crude extract-β-glucan complex of this invention has superior prebiotic potential, providing a theoretical basis for the development of functional food ingredients.

Methods and solutions are disclosed for the quantification of mixed-linkage beta-glucan in plant biomass samples. Improved alkaline pretreatment, enzymatic hydrolysis, and glucose measurement parameters are provided that increase the accuracy, precision, and sensitivity of mixed-linkage beta-glucan assays.

The application relates to a preparation method of a beta glucan supramolecular polymer, the beta glucan supramolecular polymer and application, and belongs to the technical field of supramolecular polymer preparation. The preparation method of the beta glucan supramolecular polymer comprises the following steps: introducing a schizophyllum commune liquid into a culture medium, wherein the culture medium comprises an active substance and a culture medium substrate, the mass ratio of the schizophyllum commune liquid to the active substance is 1-10:1; and the culture medium is fermented at 27-30 DEG C for 90-100 h to obtain the beta glucan supramolecular polymer loaded with the active substance. The physical wrapping and chemical cross-linking methods are avoided, the residue problem of toxic and harmful reagents is avoided, and the loading rate is effectively improved.

The present application belongs to the technical field of nutritional health food, and particularly relates to a composition for repairing oral mucosa and a preparation method and application thereof. The composition comprises, by weight of the composition: 2%-80% of yeast beta glucan, 0.5%-50% of lactobacillus salivarius powder, 0.5%-50% of lactobacillus acidophilus powder, and 0.5%-50% of paracasei lactobacillus powder. The composition for repairing oral mucosa and the auxiliary materials are further prepared into a functional food in the form of tablets, liquids, soft candies or powders. In the functional food, the composition as the main component plays a role in repairing and preventing damage to the oral mucosa. Meanwhile, the composition and the auxiliary materials are dissolved under the action of oral saliva enzymes, thereby fully contacting the oral mucosa and pathogens and emitting a sweet and sour taste, so as to bring a pleasant sensory experience to the oral cavity.

The invention provides a sodium-reduced tricholoma matsutake seasoning as well as a preparation method and application thereof, and belongs to the field of food processing. Through directional enzymolysis and microcapsule embedding ring release technologies, the tricholoma matsutake and the mushrooms are subjected to enzymolysis, the mushroom flavor and other umami components in the tricholoma matsutake and the mushrooms are released, beta glucan is obtained while the overall flavor is improved, fruit and vegetable components rich in colloid are subjected to enzymolysis, pectin and sweetening flavor components in fruits and vegetables are released, and the taste of the tricholoma matsutake and the mushrooms is improved. A natural embedding wall material is obtained, so that the problem of high-temperature flavor loss of the traditional mushroom seasoning is solved; and secondly, potassium element extraction and enrichment are performed on fruit and vegetable raw materials rich in potassium, and the salty taste is enhanced by utilizing components such as organic acid and saccharides naturally contained in fruits and vegetables, so that part of edible salt is replaced, and the sodium-reduced tricholoma matsutake seasoning which is rich in mushroom flavor and is reduced in sodium but not reduced in salty taste is obtained.

This invention belongs to the field of aquatic food technology and relates to the preparation technology of functional fish paste. The preparation method of the fish paste product of this invention includes: dissolving 2-4 parts of barley β-glucan, 1-2 parts of astaxanthin, 0.5-0.7 parts of Tween-80, and 20-25 parts of milk powder in 100 parts of water, stirring evenly, homogenizing, and then spray drying; adding 0.2 w / w% chitosan solution to the marine fish paste at a weight ratio of 8-10:1, mixing thoroughly, heating to mature, and cooling to 60-65°C; thoroughly mixing the results of the first two steps, and continuing to cool to below 55°C to form a gel, thus obtaining the final product. The fish paste product obtained by this invention has good antioxidant and anti-diarrheal effects, improving the value of the fish paste and showing good application prospects. This invention discovers that astaxanthin and barley β-glucan have a synergistic effect in antioxidant and anti-diarrheal aspects, improving the application value of barley β-glucan.

The present invention relates to a pet food supplement composition comprising: a source of resistant starch; a source of beta glucan; a probiotic; L-carnitine; and alpha lipoic acid. The pet food supplement composition can be used to promote weight loss or in the treatment of obesity.

The invention belongs to the technical field of biological materials, and provides a construction method and application of a nucleic acid transporter based on yeast beta glucan nanoparticles, beta glucan from yeast is cross-linked with 1.8 k PEI through carboxymethylation modification to prepare CMG-PEI NP to load nucleic acid, the nucleic acid transporter is applied to RNA transport, and a new way and means are provided for RNA transport. According to the invention, the structures of the CMG-PEINP and related components are evaluated, manninotriose is used for further wrapping the CMG-PEINP, a cell model is established, and the RNA transport efficiency of the CMG-PEINP transporter is evaluated. Results show that CMG-PEINP and nucleic acid can form a compound with a compact structure, the particle size meets the drug delivery requirement, and when the mass ratio of CMG-PEINP to eGFP mRNA is 48: 1, the transfection efficiency is the highest.

The invention discloses a composite nutritional food composition capable of enhancing an immune function and a preparation process, and belongs to the field of functional foods. The composition comprises two key modified components, namely a curcumin-beta-cyclodextrin inclusion compound and sulfated low-molecular fucoidin, and rhizoma curcumae longae, yeast beta glucan, zinc gluconate, a cordyceps militaris extract, ganoderma lucidum spore powder, polygonatum polysaccharide, an oyster extracting solution, plant lactobacillus and lactobacillus acidophilus are matched. The preparation process comprises the following steps: mixing the solid components except the probiotics; drying and granulating the liquid extracting solution, and mixing with the solid; and adding the probiotic powder and the auxiliary materials at low temperature, and uniformly mixing to finally prepare a capsule dosage form. Through molecular modification and scientific compounding of core active components, the bioavailability of insoluble components and the immunocompetence of natural polysaccharides are remarkably improved, all the components have a synergistic effect, the organism immune function is safely and effectively enhanced from multiple ways and multiple targets, and the product stability is good.

The disclosure relates to a fiber blend for a health benefiting nutrition formulation, comprising: a resistant starch obtained from one or more sources selected from the group consisting of green banana resistant starch, maize or corn resistant starch, and potato resistant starch, the resistant starch having a resistant starch weight; an oat beta glucan having a beta glucan weight; and a maize or corn resistant dextrin having a resistant dextrin weight. The ratio of [the resistant starch weight]:[the beta glucan weight]:[the resistant dextrin weight]=1:0.15-4:0.15-4.

The application provides an exosome composition for reducing side effects of chemotherapy treatment and a preparation method thereof, and belongs to the technical field of medicines. Methotrexate, vinblastine and daunorubicin are prepared into a co-crystal, loaded on UiO-66-NH2 connected with RGD, loaded on exosomes, and embedded in an acrylic acid, traditional Chinese medicine polysaccharide and pullulan compound to obtain a sustained-release high half-life exosome system, which is uniformly mixed with D-ribose, yeast-beta glucan and glutathione to obtain the exosome composition for reducing side effects of chemotherapy treatment. The traditional Chinese medicine polysaccharide is traditional Chinese medicine polysaccharide obtained by boiling water extraction and ethanol precipitation of radix codonopsis, angelica, polygonatum sibiricum and dendrobium officinale. The exosome composition for reducing side effects of chemotherapy treatment is prepared, drug resistance of tumor cells is reduced, drug efficacy is improved, side reactions after chemotherapy are reduced, the effect of targeted slow release of drugs is achieved, and the exosome composition has a wide application prospect.