19results about How to "Relieve itching" patented technology

The invention relates to application of cembratrienol in preparation of a medicine for preventing and / or treating psoriasis, and belongs to the technical field of biological medicine. The invention provides an application of cembratrienol in preparation of a medicine for preventing / or treating psoriasis. Researches find that cembratrienol can significantly inhibit secretion of inflammatory factors in a psoriasis-like cell model induced by M5; moreover, research finds that cembratrienol can significantly improve the skin lesion condition of an imiquimod-induced psoriasis mouse model, improve the weight loss degree of the psoriasis mouse model, relieve the pruritus condition of the psoriasis mouse model, improve the skin inflammation of the psoriasis mouse model, repair the skin barrier of the psoriasis mouse model, and improve the curative effect of the psoriasis mouse model. The body immune response of the psoriasis mouse model is reduced. Therefore, cembratrienol has a great application prospect in preparation of the medicine for preventing / treating psoriasis.

The utility model relates to the clinical technical field of dermatology, in particular to a sensitive skin care instrument which comprises a fixing frame, a first fixing ring is installed at the top end of the fixing frame, a cold compress treatment assembly is installed on the inner wall of the first fixing ring, and a second fixing ring is fixedly connected to the top end of the fixing frame and located on one side of the first fixing ring. And a fixing plate is mounted on the inner wall of the second fixing ring. According to the sensitive skin care instrument, through the arrangement of the fixing frame, the first fixing ring and the cold compress treatment assembly, when the sensitive skin care instrument is used, the fixing frame is used for fixing the first fixing ring, the face of a patient is placed in the first fixing ring, after hot compress treatment is conducted on the patient, facial pores of the patient can be shrunk through the cold compress treatment assembly, and dust and bacteria are prevented from entering the pores; by combining hot compress, the treatment effect of a patient can be improved, red, swollen and itching of sensitive skin are relieved, and the device is integrated, does not occupy the use space and reduces the trouble of carrying a machine.

This invention provides an interleukin-31 (IL-31) production inhibitor and a pharmaceutical composition comprising the inhibitor. The invention also provides a novel compound useful as an active ingredient for an IL-31 production inhibitor. These comprise a compound represented by the following formula (1) or a salt thereof as an active ingredient: wherein A is a -NH-N=C(R1)- group, a divalent N-containing 5-membered heterocyclic group, or a -NH-CO- group, wherein R1 is a hydrogen atom or a C1-4 alkyl group, B is the same or different and is a C1-6 alkyl group optionally having one hydroxyl group, a mono or di(C1-6 alkyl)amino group optionally having one hydroxyl group, a halogen atom, a halo C1-6 alkyl group, a C2-6 alkynylene group, or a carboxy group, wherein at least one C1-6 alkyl group in the mono or di (C1-6 alkyl) amino group is optionally attached to a carbon atom adjacent to a carbon atom in the phenyl group to which it is attached, to form a 5- to 6-membered ring, and n is an integer of 1 to 5.

The invention provides shampoo for controlling oil and relieving itching and a preparation method thereof, and relates to the technical field of shampoo. The shampoo is prepared from the following raw materials in parts by weight: 10 to 14 parts of camellia oil, 20 to 30 parts of plant extract, 7 to 10 parts of euglena parviflora root powder, 3 to 6 parts of vitamin E, 10 to 13 parts of butyrospermum parviflora butter, 6 to 8 parts of hydrolyzed silk protein, 7 to 9 parts of euglena parviflora polysaccharide, 4 to 7 parts of amino acid, 14 to 18 parts of surfactant, 2 to 4 parts of hydroxyethyl cellulose and 70 to 90 parts of water. The shampoo has good foaming and scalp dirt cleaning performance and can inhibit excessive secretion of sebaceous gland cells and reduce scalp grease generation, active ingredients can permeate into the inner layer of scalp to supplement moisture and nutrition, meanwhile, a protective layer can be formed on the surface layer of the scalp, the damaged scalp barrier of children is repaired, the scalp resistance is enhanced, and the hair is protected. Therefore, good oil control and itching relieving effects are achieved, and the effect is mild.

The invention relates to the technical field of fine chemical engineering and daily chemicals, and particularly discloses a preparation method and application of high-water-solubility zinc glycyrrhizinate, the high-water-solubility zinc glycyrrhizinate is prepared from natural indissolvable zinc glycyrrhizinate through three steps of precursor synthesis, ligand exchange and recrystallization refining in combination with optimization of organic ligands, and the high-water-solubility zinc glycyrrhizinate is prepared into the high-water-solubility zinc glycyrrhizinate. The zinc glycyrrhizinate is converted into high-water-solubility zinc glycyrrhizinate with a specific crystalline structure, and the application of the zinc glycyrrhizinate in the field of personal care is further expanded.

The invention relates to the technical field of skin care, and discloses a skin care appliance and a use method.According to the scheme, a thorn convex ball is placed in a hemispherical cavity of a holding part and combined with a restraining part, so that the thorn convex ball can be limited to roll in the hemispherical cavity; when a user uses the device, the thorn convex balls abut against the skin surface and move the device back and forth, so that the thorn bulges protruding out of the surface of the ball body abut against the skin surface, a plurality of touch points are provided for the skin, the itching is relieved, meanwhile, the contact area is increased, the pressure applied by the user is dispersed, and skin injuries are avoided; in the process that the appliance moves back and forth on the skin surface, the thorn convex balls can roll in the hemispherical cavities, the relative positions of the thorn convex and the skin surface are fixed (contact points of the thorn convex and the skin surface are relatively static), and the condition that the skin is dragged cannot occur in the moving process, so that the skin surface cannot be damaged, and the skin can be effectively protected while itching is relieved. And the skin is prevented from being scratched.

The application relates to the technical field of skin bacteriostatic liquid, and discloses a skin bacteriostatic liquid containing plant extracts and a preparation method thereof, which comprises the following raw materials in parts by mass: composite plant extracts containing nanocrystalline particles 15-20 parts, glycerol 3-4 parts, sodium hyaluronate 0.1-0.2 parts and purified water 75-85 parts. The composite plant extracts containing nanocrystalline particles, glycerol, sodium hyaluronate and purified water are mixed to obtain the skin bacteriostatic liquid, which has the advantages of strong bacteriostasis, long-acting bacteriostasis, mildness and no irritation, and can repair the skin barrier, realize long-acting skin bacteriostasis, reduce the repeated occurrence of skin inflammation, and relieve inflammatory skin aging.

The invention belongs to the technical field of daily chemicals, and particularly relates to a method for purifying alkaloid from oat and application of the alkaloid to preparation of an anti-allergy soothing composition. The method for purifying alkaloid from oat comprises the following steps: (1) crushing oat to obtain oat powder; (2) mixing oat and water according to a weight ratio of 1: (10-15), putting the mixture into a microwave reactor, and carrying out microwave-assisted extraction to obtain a mixture, (3) carrying out enzymolysis to obtain an enzymatic hydrolysate; (4) adding mixed bacteria into the enzymatic hydrolysate, fermenting, and sterilizing to obtain fermentation liquor; and (5) carrying out centrifugal separation on the fermentation liquor, carrying out subcritical extraction on solids obtained by centrifugal separation, and then recovering the solvent to obtain an extract containing the oat alkaloid. According to the method, the extraction rate of the oat alkaloid is high, and the synergistic effect of the oat alkaloid and the sophora flavescens extract is good.

The invention discloses an oil-control and antipruritic composition containing natural active ingredients, a preparation method and an application thereof, wherein the composition is prepared from the following Chinese medicinal raw materials in parts by weight: 1 to 20 parts of Artemisia argyi leaf, 1 to 15 parts of nettle, 1 to 10 parts of Millettia spatholobi, 1 to 10 parts of stinking peony root, 1 to 10 parts of geranium, 1 to 10 parts of peach branch, 1 to 5 parts of licorice, and 1 to 5 parts of polygonatum. The invention utilizes the theory of monarch, minister, assistant and envoy of traditional Chinese medicine, and prepares the oil-control and antipruritic composition by compounding Artemisia argyi leaf, nettle, Millettia spatholobi, stinking peony root, geranium, peach branch, licorice and polygonatum, and extracts by controlling the temperature of ethanol and water respectively, so as to effectively extract the volatile or water-insoluble active ingredients of the Chinese medicinal raw materials, so as to make the active ingredients synergistic and enhance the efficacy.

The invention belongs to the technical field of daily necessities, and specifically relates to a composition for shampooing with anti-dandruff and antipruritic effects and a preparation method thereof, comprising the following components: piroctone olamine salt, BIOTA ORIENTALIS leaf extract, PUERARIA LOBATA extract, ANEM ARRHENA ASPHODELOIDES root extract and SAPINDUS MUKORO SSI fruit extract. Chemical anti-dandruff and antipruritic agents are effectively compounded with plant extracts to overcome the defects of a single type of anti-dandruff and antipruritic agent, and the composition is mild, efficient, widely applicable, and can effectively improve the effects of removing dandruff and relieving scalp itching.

This invention belongs to the field of traditional Chinese medicine compound technology, and discloses a traditional Chinese medicine compound and mask preparation for anti-inflammatory, soothing and repairing facial dermatitis. The traditional Chinese medicine compound is made from the following traditional Chinese medicines in parts by weight: purslane: 10-15 parts, phellodendron bark: 10-12 parts, burnet root: 10-12 parts, and licorice root: 6-10 parts. This invention selects four medicinal materials—purslane, phellodendron bark, burnet root, and licorice root—and formulates them in a clear and coordinated manner. The herbs work synergistically, addressing both the symptoms and the root cause. It can clear heat and dampness, cool the blood and detoxify, and also has modern pharmacological activities such as anti-inflammatory and antibacterial effects, and promotes wound healing. It can effectively improve various skin lesions such as erythema, swelling, itching, and burning in facial dermatitis. Moreover, the medicine is mild, has low irritation, acts directly on the affected area, has a direct effect, and is highly safe.

Use of a white pomegranate extract for the preparation of a composition for improving bacterial inflammation in the intimate area, the white pomegranate extract being obtained by water extraction of whole fruit of Punica granatum L. cv. Albescens DC.

The invention provides a wool acetic acid intertwined composite yarn and a preparation method and application thereof. The wool and acetic acid intertwined composite yarn comprises inner-layer fibers and outer-layer fibers, the inner-layer fibers are of a core-spun structure with polyester filaments as core yarn and wool as a wrapping layer, and the outer-layer fibers are of a wrapping structure formed by wrapping diacetic acid filaments on the surfaces of the inner-layer fibers; wherein the wrapping density of the diacetate filaments is 5-15 circles / cm, the rotation angle is 20-60 degrees, and the outer layer coverage rate is 15-95%. The polyester filament yarn is used as the core yarn of the inner-layer fiber, the polyester core yarn is wrapped by the wool, the outer-layer diacetate filament yarn wraps the inner-layer fiber according to specific parameters, and the outer-layer diacetate filament yarn and the polyester filament yarn of the inner-layer fiber form a stable reinforced network, so that in the process that the yarn is subjected to tension, friction and tearing force, the yarn is not prone to deformation. The stress can be effectively dispersed and transmitted to the polyester core yarn, so that the overall breaking strength and the fatigue resistance of the composite yarn are greatly improved.

The utility model discloses a medicine smearing device for otitis externa, which belongs to the technical field of medicine smearing and comprises an injector used for extracting and smearing medicine and a smearing device used for stretching into an ear canal to smear the medicine, and the smearing device is sleeved at an injection port of the injector and is communicated with the injection port. The smearing device comprises a smearing pipeline, a smearing sleeve, a smearing opening, a smearing head and an angle adjuster used for changing the angle of the smearing opening, the smearing pipeline is arranged at the injection opening of the injector in a sleeving mode and is communicated with the injection opening, the smearing sleeve is rotationally connected to the tail end of the smearing pipeline, and the smearing sleeve is communicated with the smearing pipeline; according to the device, when a patient needs to smear medicine on otitis externa, the medicine needing to be smeared is extracted through the injector, after the medicine is extracted, the injector is held by a hand to stretch the smearing device into the position, needing to be smeared, in the ear canal of the patient, and the medicine smearing operation on the otitis externa is achieved through pushing and shooting of the injector.

The utility model discloses a desktop cat climbing frame relates to pet furniture technical field, including main frame, clamp left and clamp right. The utility model discloses desktop cat climbing frame sets up lifting mechanism, horizontal rotation mechanism, horizontal telescopic mechanism, and all are through remote control control, and have mechanical self -locking function simultaneously, and further adjust the position of multifunctional cat nest, let cat can pursue multifunctional cat nest, and it is convenient for people to carry out remote control operation, and promptly interact with cat and carry out interactive game, and relieve work fatigue, and through set up wool rubbing stick and let cat use cheek, forehead and chin etc. Part goes and scratches, and then leaves the exclusive smell, marks the safe territory, and relieves the anxiety, and the scratch wool rubbing stick can help it to scratch off the eye dirt and food residue, thereby combing the facial hair, and when the molting period or the skin slightly itchy, can provide self -service scratch point, and relieve the itching.

This invention belongs to the field of daily chemical products technology, specifically relating to a pure herbal hair growth and anti-hair loss shampoo based on multi-pathway synergistic effects and its preparation method. The herbal hair growth and anti-hair loss shampoo comprises: hair follicle regulating ingredients, blood circulation promoting ingredients, antibacterial and antipruritic ingredients, and natural surfactant ingredients. This invention scientifically proportions the above ingredients. The extract obtained from the hair follicle regulating ingredients regulates sebum secretion in hair follicles; the extract obtained from the blood circulation promoting ingredients promotes blood circulation in scalp capillaries; the extract obtained from the antibacterial and antipruritic ingredients inhibits scalp infections and hair follicle inflammation; and the surfactants give the shampoo good stability. This invention, through the multi-pathway synergistic effects of the above components, solves the shortcomings of existing herbal shampoo products, such as simple formulas, insufficient extraction of effective ingredients, reliance on chemical surfactants, and limited efficacy. It has the advantages of being natural, gentle, non-irritating, and having a high utilization rate of effective ingredients.

The present invention relates to a composition containing a slow-release anti-dandruff and antipruritic effect, and its preparation method and application. The present invention group is prepared by combining soybean extract, glabridin, maitake polysaccharide, grape seed extract, oat extract, pine pollen extract, and tea tree oil. Maitake polysaccharide has a promoting effect on the generation of hyaluronic acid, and the components such as phospholipids and lecithin in the soybean extract have a moisturizing effect. In the presence of pine pollen extract, the damaged barrier surface structure of the scalp can be repaired, the scalp barrier can be enhanced, and the stratum corneum barrier of the scalp and the hydration of the stratum corneum can be avoided from being destroyed, and symptoms such as scalp dandruff are further produced. In the present invention, ceramide is also used to coat the composition, sodium alginate-chitosan is used for coating, glutaraldehyde is modified on the surface of the microcapsule, and the aldehyde group of glutaraldehyde forms a Shiff base with the amino group of chitosan, which has a good antibacterial effect and can enhance the antibacterial effect of the composition.

The invention discloses a gel composition for cleaning capsaicin on a skin surface and application of the gel composition. The gel composition comprises an organic solvent, a surfactant, ethyl oleate, menthol, a gel matrix and water, the gel composition is used again after the capsaicin is applied to the skin surface for a proper time, so that the side effects generated by the capsaicin are reduced.

The invention belongs to the technical field of pharmacy, and particularly relates to minoxidil liniment as well as a preparation method and application thereof. The minoxidil liniment comprises the following components: minoxidil, an alcoholic solution, a stabilizer, an oat extract and water, wherein the stabilizer comprises EDTA (Ethylene Diamine Tetraacetic Acid)-tetrasodium, panthenol and hydroxypropyl cellulose. By utilizing the synergistic effect of the EDTA-tetrasodium, the panthenol and the hydroxypropyl cellulose, the preparation process is optimized, so that the effectiveness and the stability of the minoxidil serving as the raw material medicine can be effectively improved, the validity period of the minoxidil can be prolonged, and the medication compliance can be improved. According to the liniment disclosed by the invention, the oat extract is adopted as an auxiliary material of the liniment, so that side effects of minoxidil are reduced, red and swollen, pruritus and discomfort possibly caused by minoxidil can be effectively relieved, damaged scalp skin barriers are helped to be repaired, microinflammation around hair follicles is reduced, and a healthier environment is created for hair growth.