19 results about "Folliculitis" patented technology

The invention provides a phenolic amide derivative and application thereof, relates to application of a compound and a composition thereof in preparation of cosmetics or medicines for preventing, treating and relieving acne, and provides a medicine or cosmetic composition which comprises a therapeutically effective amount of compound, or at least one of a racemate, a stereoisomer, a geometric isomer, a tautomer, an isotope label, a hydrate, a solvate, a polymorphic substance, a metabolite, a prodrug and pharmaceutically acceptable salt or ester. The present invention provides the prevention, treatment or alleviation of skin problems associated with Propionibacterium acnes, including comedo, acne, folliculitis; according to the phenolic amide derivative with a novel structure, the structural type of the phenolic amide compound is enriched, the activity of inhibiting propionibacterium acnes is increased on the basis of retaining the anti-inflammatory activity of the phenolic amide compound, and the aim of treating both symptoms and root causes of skin problems related to the propionibacterium acnes is achieved.

The invention provides Chinese herbal medicine hair-nourishing and color-protecting cream, and belongs to the technical field of hair-protecting products. The invention relates to a Chinese herbal medicine hair nourishing and color protecting cream which can effectively solve various hair problems, such as alopecia, white hair, scurf, itching in head, folliculitis, dry and dry hair and the like. The hair nourishing cream provided by the invention is safe, non-toxic and free of side effects. When in use, the traditional Chinese medicine composition is externally applied to hair follicles at the roots of hair, and through the principle of transdermal administration, the traditional Chinese medicine composition deeply permeates into the skin layers of the hair follicles, activates hair cells and enables effective components in the Chinese herbal medicines to fully permeate into the hair follicles, so that the traditional Chinese medicine composition has a remarkable repairing effect on various hair problems and helps more people to get rid of hair troubles.

The invention discloses application of an Aldicanol compound in preparation of a medicine for treating chronic skin inflammation, and belongs to the technical field of medicines. In order to solve the problem that a method for effectively treating chronic scytitis lacks in the prior art, the invention provides an application of an Aldicanol compound in preparation of a medicine for treating chronic scytitis, the Aldicanol compound is extracted from dryopteris fragrans glandular hair, and the Aldicanol compound has the effects of remarkably improving skin erythema caused by chronic scytitis, reducing scales, improving the curative effect of chronic scytitis, improving the curative effect of chronic scytitis and the like. The spleen index is reduced; the skin epidermis thickness caused by chronic skin inflammation is obviously reduced, inflammatory cell infiltration is reduced, and hair follicle inflammation is obviously weakened; proinflammatory factors can be effectively inhibited, and expression of anti-inflammatory factors can be effectively promoted; the Aldicanol compound can be applied to the treatment of chronic skin inflammation.

The invention discloses a traditional Chinese medicine external spray for treating skin diseases, and belongs to the technical field of traditional Chinese medicines. The spray is prepared from thirteen raw material medicines in specific parts by weight, such as spina gleditsiae, nidus vespae, catechu and scutellaria baicalensis, through three-dimensional complementary formula compatibility of'detoxification, antibiosis and repair ', core effective components are extracted through a constant-temperature dynamic water extraction method according to the ratio of the weight of the medicinal materials to the volume of water for extraction of 1: 8; the preparation method comprises the following steps: flocculation and clarification of chitosan, stabilization treatment of dipotassium glycyrrhizinate, pH adjustment, construction of a composite solvent system, terminal sterile filtration and other optimization processes in sequence. The spray provided by the invention has the comprehensive effects of removing necrotic tissue and promoting granulation, killing parasites to relieve itching, diminishing swelling and expelling toxin, and clearing heat and promoting diuresis, is suitable for treating various skin diseases such as eczema, folliculitis, tinea pedis and the like, and is scientific in formula, advanced in process, high in product purity, good in stability, good in transdermal absorbability, remarkable in curative effect and safe and convenient to use.

The invention discloses a traditional Chinese medicine composition for caring scalp hair and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine preparations. The traditional Chinese medicine composition is blood-nourishing and hair-growing liquid and consists of traditional Chinese medicine powder and home-brewed white spirit, wherein the traditional Chinese medicine powder comprises radix polygoni multiflori preparata, fructus psoraleae, rhizoma drynariae, flos carthami, rhizoma chuanxiong, fructus cnidii, cortex dictamni, cacumen biotae and radix rehmanniae preparata, and the home-brewed white spirit is prepared by cooking, fermenting and distilling black glutinous rice, sorghum, black beans and triticale. The traditional Chinese medicine composition can be used for specifically solving the problems of hair follicle blockage, epifolliculitis, alopecia areata, alopecia, white hair and the like caused by large working pressure, staying up late, chemical washing and care residues and the like of modern people, is safe and mild, has no obvious adverse reaction, gives consideration to treatment and daily maintenance, and is wide in application range.

This application provides the use of an antimicrobial peptide in the preparation of skin care products. The antimicrobial peptide of this application can effectively inhibit *Propionibacterium acnes* and *Malassezia*, thereby preventing skin problems such as acne, skin inflammation, and dandruff caused by the overgrowth of these two bacteria. Therefore, the antimicrobial peptide of this application has skin care uses in inhibiting acne, relieving skin inflammation such as folliculitis, pityriasis versicolor, and seborrheic dermatitis, and in inhibiting dandruff, and has significant practical value.

The present invention relates to the cosmetic use of phytosterols to protect and / or restore the skin microbiota and / or to prevent and / or reduce the unsightly, unpleasant, and / or uncomfortable manifestations of skin microbiota alteration. It further relates to a cosmetic treatment method comprising the topical application of phytosterols to at least one area of ​​skin, advantageously the scalp, to protect and / or restore the skin microbiota and / or to prevent and / or reduce the unsightly, unpleasant, and / or uncomfortable manifestations of skin microbiota alteration.Finally, it concerns phytosterols for their use in the treatment and / or prevention and / or reduction of the occurrence of a pathology associated with an alteration of the skin microbiota, in particular chosen from the group consisting of acne, psoriasis and bacterial and / or fungal infections, ulcers, herpes, boils, folliculitis, abscesses, sycosis, impetigo, ecthyma, erysipelas, mycoses such as candidiasis or dermatophytoses such as ringworm and / or scabies, pigmentary and / or acne scars as well as their combinations and / or in the treatment and / or prevention of superinfection of wounds and / or in the prevention of spots.

The invention relates to a washing and caring composition with dandruff removing, itching relieving and repairing effects and a preparation method of the washing and caring composition, and belongs to the technical field of daily chemicals. Aiming at dandruff formation and itching factors of scalp, the piroctone olamine salt, palmitoyl tetrapeptide-10, tetrapeptide-1 and speranskia herb extract are correspondingly compounded to play a role in removing dandruff and relieving itching, and the limitation of a single component is made up by compounding chemical components and plant extracts, so that more efficient and milder scalp care is realized. In addition, the dihydrooat acyl o-aminobenzoic acid, pyridoxine tripalmitate and quaternary ammonium salt-73 are combined for use, so that the shampoo also has an excellent synergistic repairing capability on scalp with symptoms such as acne, red and swollen, slight folliculitis and the like.

The present invention provides compositions and methods for orally and / or topically treating skin diseases and conditions, such as acne, atopic dermatitis, psoriasis, facial redness, folliculitis, dry skin, itchy skin, hyperpigmentation, aging, wrinkles, etc., by administering to a subject in need thereof a pharmaceutical composition or dietary supplement comprising an in vitro grown grape cell line culture. Additionally, the present invention provides methods and compositions for treating skin conditions and diseases, such as acne, atopic dermatitis, psoriasis, facial redness, folliculitis, dry skin, itchy skin, aging, wrinkles, etc., by topically administering to a subject in need thereof a pharmaceutical composition or cosmetic composition comprising an in vitro grown grape cell line culture.

This invention addresses the prevalent hair loss problem in modern people by providing a pharmaceutical composition comprising Sanguisorba officinalis extract and Sophora flavescens extract. Topical application improves hair growth in a hair loss model mouse, resulting in thicker, shinier hair. Both hair weight and length show significant improvement compared to the model group, the Sanguisorba officinalis-only group, and the Sophora flavescens-only group, indicating synergistic effects. This may be related to its inhibition of Malassezia scalp, thereby improving the scalp environment. In particular, the co-decoction extract of Sanguisorba officinalis and Sophora flavescens shows superior efficacy compared to physically mixed Sanguisorba officinalis and Sophora flavescens extracts in the same proportion. Optimal efficacy was achieved at a Sanguisorba officinalis:Sophora flavescens weight ratio of 2:8, demonstrating the therapeutic advantage of the co-decoction extract. In volunteer use cases, the co-decoction extract showed similar excellent effects in improving scalp sebum secretion and narrowing the hair loss area, as well as a significant clearing effect on folliculitis.

The present application relates to the technical field of antibacterial peptides, in particular to an antibacterial peptide for inhibiting Malassezia, a preparation method and application thereof. The antibacterial peptide for inhibiting Malassezia comprises any one of the following (a)-(d) polypeptides: (a) a polypeptide comprising an amino acid sequence shown in SEQ ID NO. 1, or a polypeptide consisting of amino acid residues shown in SEQ ID NO. 1; (b) a polypeptide formed by substitution, deletion and / or addition of one or more amino acid residues in the amino acid sequence defined in (a); (c) a polypeptide obtained by modifying the N-terminal and / or C-terminal of the polypeptide defined in (a); and (d) a polypeptide having 99% or more, 95% or more, 90% or more, 85% or more, or 80% or more homology with the amino acid sequence defined in (a). The antibacterial peptide for inhibiting Malassezia has good safety to the skin, and can be used for treating dandruff, seborrheic dermatitis, tinea versicolor and Malassezia folliculitis caused by Malassezia fungal infection, and can be applied to cosmetics or external-use drugs for treating dandruff, seborrheic dermatitis, tinea versicolor and Malassezia folliculitis. The antibacterial peptide has significant antibacterial effect on Malassezia restricta and Malassezia furfur, and has great application value.

The invention discloses a pharmaceutical composition for treating hypertrophic scars and / or keloids. The pharmaceutical composition is prepared from the following raw materials in parts by weight: 15-25 parts of gallnut, 15-25 parts of smoked plum, 15-25 parts of senecio scandens, 15-25 parts of fructus cnidii, 10-20 parts of radix angelicae, 10-20 parts of cortex lycii radicis, 170-230 parts of vinegar and 170-230 parts of honey. The composition disclosed by the invention has the effects of detoxifying, diminishing swelling, astringing dampness and relieving itching. The traditional Chinese medicine composition has obvious effects on hypertrophic scars and keloids formed after trauma, operation, burns and scalds, acne, folliculitis and other inflammations, and itching and pain caused by the hypertrophic scars and keloids.

The application discloses an antibacterial, anti-inflammatory, acne-removing, acne and folliculitis improving composition and application thereof. The composition provided by the application contains the following components in a mass ratio: nano-biological sulfur:salicylic acid:gentian root extract:trans-4, 5- dihydroxy-4-(2-hydroxyethyl)-2-methyl-2H-furan-3-one:succinic acid=(1-5):(5000-50000):(5000-50000):(10000-50000):(2000-10000). The composition has significant antibacterial and anti-inflammatory effects, and the components have synergistic effects. The composition can destroy pathogenic bacterial cell membranes, inhibit staphylococcus aureus, propionibacterium acnes and malassezia, reduce the level of inflammatory factors, remove acne, improve acne and folliculitis, relieve skin discomfort, make the skin look fresh, and be used for preparing more skin disease treatment drugs and acne-removing products.

The present invention relates generally to the use of a compound of formula (I) as defined herein as an active ingredient. Furthermore, the present invention relates to a method for inhibiting or preventing the growth of one or more microorganisms, and a method for inhibiting or reducing the conversion of sweat components to odorous compounds. The invention also relates to a compound of formula (I) as defined herein for use in the treatment of inflammation, post-inflammatory pigmentation, atopic dermatitis, bacterial vaginosis, tinea pedis, neonatal exfoliative dermatitis, contagious impetigo, furuncle and carbuncle, folliculitis, impetigo and / or erysipelas and for use as an antimicrobial agent, a mixture comprising one or two compounds of formula (I) as defined herein, and a mixture comprising one or two compounds of formula (I) as defined herein and one or more other antimicrobial agents. Finally, the present invention relates to a deodorant, a rinse-on product and a rinse-free product as defined herein.

The present invention relates to a composition comprising at least one oxazoline, such as OX100, for inhibiting the growth of Malassezia yeasts and / or for preventing and / or treating conditions caused by Malassezia yeasts, seborrheic dermatitis, cradle cap, Malassezia folliculitis, dandruff, Pityriasis versicolor or Pityriasis capitis. The present invention also relates to a composition comprising at least one oxazoline such as OX100, at least one compound such as malic acid diester and a vegetable oil oleodistillate and / or arabinogalactan, and to the use of same for preventing and / or treating, in particular, affections caused by Malassezia yeasts, seborrheic dermatitis, cradle cap, Malassezia folliculitis, dandruff, Pityriasis versicolor or Pityriasis capitis.

A peptide-ionic liquid conjugate for the prevention and / or treatment of skin disorders. The peptide-ionic liquid conjugate comprises a cosmeceutical peptide comprising up to 10 amino acids and at least one ionic liquid comprising saturated or unsaturated hydrocarbon chain substituents from C1 to C18. The peptide-ionic liquid conjugates herein disclosed are suitable against skin disorders, such as, e.g., melanoma, non-melanoma skin cancers, diabetic foot ulcers, venous leg ulcers, pressure ulcers, acne, candidiasis, cellulitis, dermatophytoses, erysipelas, folliculitis, impetigo, psoriasis, rosacea, or eczema (atopic dermatitis), since they present potent activity against either antibiotic-susceptible strains or multidrug resistant clinical isolates of both Gram-positive and Gram-negative, a bactericidal type of action, anti-inflammatory and immunomodulatory effects, and collagenesis-inducing effects. Further disclosing a topical composition comprising the peptide-ionic liquid conjugates and uses thereof.

The present application relates to the technical field of external preparation preparation, and discloses a kind of nano-dispersed composition for external use prevention and treatment hair follicle related pathogenic microorganism.The composition comprises free octanoic acid 0.1-1.5%, free decanoic acid 0.1-1.5%, free lauric acid 0.1-1.5%, polyoxyethylene hydrogenated castor oil 3-10% and polyol solvent 5-20% by total weight of composition.The pH of the composition is 3.0-5.0, the particle size is 20-100 nm, and PDI≤0.3.The composition remains clear and transparent after 3 freeze-thaw cycles at-20℃ / 4℃, and exhibits synergistic antibacterial effect on hair follicle related pathogenic microorganisms such as malassezia furfur, propionibacterium acnes and staphylococcus aureus at a lower active ingredient dosage.The ternary medium-chain fatty acid nano-dispersed system of the present application has synergistic antibacterial effect and low-temperature stability, and can be used to prepare external preparations for regulating hair follicle skin microecology, inhibiting excessive proliferation of hair follicle related microorganisms or preventing and treating acne, folliculitis, malassezia related skin problems and dandruff related problems.

A medium comprising a nucleic acid fragment mixture, and a stem cell culture technique based on same for high-efficiency production of stem cell-derived extracellular vesicles and proteins, of the present invention, can significantly increase the expression level of proteins such as growth factors and the production of extracellular vesicles of stem cells. Stem cells cultured by the method or extracellular vesicles obtained therefrom have a high protein amount, and thus can be effectively used in the cosmetic field for applications such as skin whitening, skin wrinkle reduction, hair color change, hair loss alleviation or prevention, acne alleviation, ultraviolet protection, skin inflammation alleviation, cell regeneration, antioxidant activity, anti-aging, skin moisturizing, skin condition improvement, skin soothing and stress relief, or skin texture refining and elasticity enhancement, and in the medical field for applications such as hair loss, inflammatory diseases, acne and folliculitis management, and scar prevention.

This invention belongs to the field of daily chemical products technology, specifically relating to a pure herbal hair growth and anti-hair loss shampoo based on multi-pathway synergistic effects and its preparation method. The herbal hair growth and anti-hair loss shampoo comprises: hair follicle regulating ingredients, blood circulation promoting ingredients, antibacterial and antipruritic ingredients, and natural surfactant ingredients. This invention scientifically proportions the above ingredients. The extract obtained from the hair follicle regulating ingredients regulates sebum secretion in hair follicles; the extract obtained from the blood circulation promoting ingredients promotes blood circulation in scalp capillaries; the extract obtained from the antibacterial and antipruritic ingredients inhibits scalp infections and hair follicle inflammation; and the surfactants give the shampoo good stability. This invention, through the multi-pathway synergistic effects of the above components, solves the shortcomings of existing herbal shampoo products, such as simple formulas, insufficient extraction of effective ingredients, reliance on chemical surfactants, and limited efficacy. It has the advantages of being natural, gentle, non-irritating, and having a high utilization rate of effective ingredients.