4 results about "Folliculitis" patented technology

This application provides the use of an antimicrobial peptide in the preparation of skin care products. The antimicrobial peptide of this application can effectively inhibit *Propionibacterium acnes* and *Malassezia*, thereby preventing skin problems such as acne, skin inflammation, and dandruff caused by the overgrowth of these two bacteria. Therefore, the antimicrobial peptide of this application has skin care uses in inhibiting acne, relieving skin inflammation such as folliculitis, pityriasis versicolor, and seborrheic dermatitis, and in inhibiting dandruff, and has significant practical value.

This invention addresses the prevalent hair loss problem in modern people by providing a pharmaceutical composition comprising Sanguisorba officinalis extract and Sophora flavescens extract. Topical application improves hair growth in a hair loss model mouse, resulting in thicker, shinier hair. Both hair weight and length show significant improvement compared to the model group, the Sanguisorba officinalis-only group, and the Sophora flavescens-only group, indicating synergistic effects. This may be related to its inhibition of Malassezia scalp, thereby improving the scalp environment. In particular, the co-decoction extract of Sanguisorba officinalis and Sophora flavescens shows superior efficacy compared to physically mixed Sanguisorba officinalis and Sophora flavescens extracts in the same proportion. Optimal efficacy was achieved at a Sanguisorba officinalis:Sophora flavescens weight ratio of 2:8, demonstrating the therapeutic advantage of the co-decoction extract. In volunteer use cases, the co-decoction extract showed similar excellent effects in improving scalp sebum secretion and narrowing the hair loss area, as well as a significant clearing effect on folliculitis.

The present application relates to the technical field of external preparation preparation, and discloses a kind of nano-dispersed composition for external use prevention and treatment hair follicle related pathogenic microorganism.The composition comprises free octanoic acid 0.1-1.5%, free decanoic acid 0.1-1.5%, free lauric acid 0.1-1.5%, polyoxyethylene hydrogenated castor oil 3-10% and polyol solvent 5-20% by total weight of composition.The pH of the composition is 3.0-5.0, the particle size is 20-100 nm, and PDI≤0.3.The composition remains clear and transparent after 3 freeze-thaw cycles at-20℃ / 4℃, and exhibits synergistic antibacterial effect on hair follicle related pathogenic microorganisms such as malassezia furfur, propionibacterium acnes and staphylococcus aureus at a lower active ingredient dosage.The ternary medium-chain fatty acid nano-dispersed system of the present application has synergistic antibacterial effect and low-temperature stability, and can be used to prepare external preparations for regulating hair follicle skin microecology, inhibiting excessive proliferation of hair follicle related microorganisms or preventing and treating acne, folliculitis, malassezia related skin problems and dandruff related problems.

This invention belongs to the field of daily chemical products technology, specifically relating to a pure herbal hair growth and anti-hair loss shampoo based on multi-pathway synergistic effects and its preparation method. The herbal hair growth and anti-hair loss shampoo comprises: hair follicle regulating ingredients, blood circulation promoting ingredients, antibacterial and antipruritic ingredients, and natural surfactant ingredients. This invention scientifically proportions the above ingredients. The extract obtained from the hair follicle regulating ingredients regulates sebum secretion in hair follicles; the extract obtained from the blood circulation promoting ingredients promotes blood circulation in scalp capillaries; the extract obtained from the antibacterial and antipruritic ingredients inhibits scalp infections and hair follicle inflammation; and the surfactants give the shampoo good stability. This invention, through the multi-pathway synergistic effects of the above components, solves the shortcomings of existing herbal shampoo products, such as simple formulas, insufficient extraction of effective ingredients, reliance on chemical surfactants, and limited efficacy. It has the advantages of being natural, gentle, non-irritating, and having a high utilization rate of effective ingredients.