11 results about "Cellulitis" patented technology

The present application relates to a peptide-ionic liquid conjugate for the prevention and / or treatment of skin conditions. The peptide-ionic liquid conjugate comprises a pharmaceutical cosmetic peptide containing up to 10 amino acids and at least one ionic liquid containing a C1 to C18 saturated or unsaturated hydrocarbon chain substituent. The peptide-ionic liquid conjugates disclosed herein are useful for combating skin conditions, such as melanoma, non-melanoma skin cancer, diabetic foot ulcer, lower limb vein ulcer, stress ulcer, acne, candidiasis, cellulitis, dermatophytosis, erysipelas, folliculitis, impetigo, psoriasis, rosacea or eczema (atopic dermatitis), and the like. As they exhibit potent activity, bactericidal effect, anti-inflammatory and immunomodulatory effect and collagen production inducing effect on antibiotic sensitive strains or gram-positive and gram-negative multi-drug resistant clinical isolates. The present application further discloses topical compositions comprising the peptide-ionic liquid conjugates and uses thereof.

A composition comprising isolated Streptococcus pyogenes extracellular vesicles (EVs) suspended in a vehicle, for use in eliciting an adaptive immune response against group A streptococcus (GAS) in a subject. The EVs may comprise antigens MtsA, Spy_1228, PrsA1, PrsA2, SPy_0319 and / or GlnP. A composition comprising isolated S. pyogenes protein(s) MtsA, SPy_1228, PrsA1, PrsA2, GlnP, SPy_0319 and / or MalX. The compositions may be used for inducing protective immunity in a subject against a GAS infection, such as streptococcal pharyngitis, scarlet fever, impetigo, streptococcal meningitis, streptococcal sinusitis, necrotizing fasciitis, cellulitis, streptococcal toxic shock syndrome, rheumatic fever and post-streptococcal glomerulonephritis.

The present invention relates to a dental oral drainage tube which, in dentistry or oral and maxillofacial surgery, is inserted into an infection site, such as an abscess or cellulitis, or into a site where pain and edema are expected after surgery, to drain pus, tissue fluid, or blood to the outside and prevent pooling around the surgical site. The drainage tube extends in a longitudinal direction, includes a radiopaque line on an outer or inner surface, and has a body providing a passage for fluid movement. A drainage hole is formed in the longitudinal direction of the body to introduce pus, tissue fluid, or blood into the passage, and a plurality of notch lines are formed on an outer surface of the body to limit the moving direction, thereby minimizing discomfort, preventing separation from the insertion position, and shortening the recovery period after surgery.

The present invention relates to a dental drain tube, and more particularly, to a dental drain tube for oral use, and more particularly, to a dental drain tube for oral use, which can prevent blood accumulation of abscesses and infections in infected sites where abscesses such as abscesses and cellulitis are formed in dentistry, oral maxillofacial surgery or the like, and sites where swelling is expected to be severe after surgery. The present invention provides a drain tube for discharging to the outside, and discharges abscess, tissue or the drain tube from the most inconvenient position of post-operation discharge. The present invention relates to a dental oral drain tube capable of shortening the recovery time, for which the present invention extends in the longitudinal direction, has a radiation-impermeable line on either the outer surface or the inner surface, is inserted into a desired site of postoperative pain and swelling, fevers at a surgical site, and discharges to the outside. A channel extending along the length direction and providing channels for movement of pus, interstitial fluid or blood to prevent accumulation of interstitial fluid or blood; a drainage hole formed along the longitudinal direction of the main body and through which pus, interstitial fluid, or blood outside the main body flows into the channel; forming a plurality of groove lines on the outer surface of the main body to limit the moving direction of the main body; the method is characterized by including.

A composition comprising isolated Streptococcus pyogenes extracellular vesicles (EVs) suspended in a vehicle, for use in eliciting an adaptive immune response against group A streptococcus (GAS) in a subject. The EVs may comprise antigens MtsA, Spy_1228, PrsA1, PrsA2, SPy_0319 and / or GlnP. A composition comprising isolated S. pyogenes protein(s) MtsA, SPy_1228, PrsA1, PrsA2, GlnP, SPy_0319 and / or MalX. The compositions may be used for inducing protective immunity in a subject against a GAS infection, such as streptococcal pharyngitis, scarlet fever, impetigo, streptococcal meningitis, streptococcal sinusitis, necrotizing fasciitis, cellulitis, streptococcal toxic shock syndrome, rheumatic fever and post-streptococcal glomerulonephritis.

The present invention relates to circulatory compression girdles for reducing mild or class I, moderate or class II, and severe or class III cellulitis that remain in a fixed position, thereby preventing unwanted slippage and compression. The lymphatic and venous systems thus benefit, providing an increase in the venous flow velocity and a decrease in the distension of the vein wall, venous hypertension of the lower extremities and symptoms of a swollen extremity, thereby favouring venous return and ultimately improving venous flow and return.

The present disclosure provides immunogenic compositions comprising at least one recombinant polypeptide antigen derived from an Enterococcus bacterium (e.g., E. faecalis, E. faecium, E. durans). The disclosure further provides methods, and uses of the immunogenic compositions, for protecting or treating a subject from infection by an Enterococcus bacterium. Such infections may cause, or worsen, conditions such as root canal failure, endocarditis, bacteremia, urinary tract infections, prostatitis, intraabdominal infection, cellulitis, dysbiotic gastrointestinal tract, prosthetic joint infection, or wound infections.

To provide a pharmaceutical composition for use in a method of treating a skin condition.SOLUTION: Provided is a pharmaceutical composition for use in a method of treating a skin condition of a subject. The method comprises administering intradermally to the subject a botulinum neurotoxin: herein, following administration, the botulinum neurotoxin induces secretion of one or more sebaceous lipid(s) selected from a squalene, a fatty acid, a cholesterol, and a wax ester to an epidermal layer of skin; and the skin condition is selected from a group consisting of xerosis, dehydrated, dry or cracked skin, eczema, atopic eczema, type 2 Gaucher disease, Sjogren-Larsson syndrome, ichthyosis, lamellar ichthyosis, X-linked ichthyosis, bullous ichthyosiform erythroderma, essential FFA deficiency, aged dry skin, anhidrotic ectodermal dysplasia, Netherton syndrome, actinic keratosis, carbuncle, cellulitis, skin cancer, and lichen pilaris.SELECTED DRAWING: Figure 3

A disposable wound care garment with multiple layers may cover a wound on the epidermis and wick away and store leakage of fluids from the wound. The wound garment may include a medication temporary storage and dispensing region to dispense medication to the wound on the epidermis, while also wicking away fluid. The wound garment may be used on extremities, such as, for example, the legs or arms. The wound care garment may be a component of a treatment plan for conditions, such as, for example, lymphedema, primary lymphedema, cellulitis, congestive heart failure, renal failure, and chronic venous insufficiency.

A peptide-ionic liquid conjugate for the prevention and / or treatment of skin disorders. The peptide-ionic liquid conjugate comprises a cosmeceutical peptide comprising up to 10 amino acids and at least one ionic liquid comprising saturated or unsaturated hydrocarbon chain substituents from C1 to C18. The peptide-ionic liquid conjugates herein disclosed are suitable against skin disorders, such as, e.g., melanoma, non-melanoma skin cancers, diabetic foot ulcers, venous leg ulcers, pressure ulcers, acne, candidiasis, cellulitis, dermatophytoses, erysipelas, folliculitis, impetigo, psoriasis, rosacea, or eczema (atopic dermatitis), since they present potent activity against either antibiotic-susceptible strains or multidrug resistant clinical isolates of both Gram-positive and Gram-negative, a bactericidal type of action, anti-inflammatory and immunomodulatory effects, and collagenesis-inducing effects. Further disclosing a topical composition comprising the peptide-ionic liquid conjugates and uses thereof.

A composition for treatment of cellulitus is provided that includes by weight: about 85% transdermal cream; an effective amount of at least one antibiotic; about 5% Ketoprofen; and about 5% Lidocaine. The composition has a density of about 1 gram per milliliter.