The invention discloses a traditional Chinese medicine paste for treating impetigo and a preparation method of the paste. The paste comprises raw materials in parts by weight as follows: 15-20 parts of dandelion, 10-15 parts of radix sophorae flavescentis, 5-10 parts of coptis chinensis, 10-15 parts of radix ampelopsis, 12-18 parts of radix rhapontici, 8-14 parts of scutellaria baicalensis, 10-15 parts of amur cork tree barks, 5-10 parts of selfheal, 16-22 parts of shrub althea flowers, 8-14 parts of honeysuckle, 10-15 parts of cucumber stems, 5-10 parts of gentian roots, 10-15 parts of barks of Japanese pagodatree, 10-15 parts of muskmelon roots, 8-14 parts of indigo naturalis, 6-12 parts of broad bean skin, 5-10 parts of licorice, 10-15 parts of waxberry's leaves, 6-12 parts of Chinese teasel roots, 7-13 parts of herba violae, 10-15 parts of cuttle bones, 5-10 parts of tenuifolia, 12-18 parts of common sage herb, 10-15 parts of radices sileris, 5-10 parts of dried alum, 10-15 parts of calomel, 8-14 parts of calamine and appropriate sesame oil. Various medicines are combined and complementary, so that the paste has effects of sterilization, resisting inflammation, relieving swelling and pain, clearing heat, drying dampness and astringing and promoting granulation; can promote skin cells to grow quickly; and is obvious in curative effect, quick in effect, short in treatment course, high in cure rate, free of relapse after cure, and free of scars, any side effects and adverse effects when used for treating the impetigo.