130 results about "Cutaneous Disorders" patented technology

This device incorporates an array of light emitting diodes (LED) of several specific wavelengths that are used to provide therapy to visible and invisible living tissue or skin disorders that react to various wavelengths of light. Furthermore the device uses a combination of high level of perforation metal core circuit boards, heat transfer pads, heat sinks and forced air cooling and electronic thermal management to achieve continuous high intensity light output to therapy areas along with long LED life. The invention is using replaceable LED modules enabling device maintenance by user operators not trained as maintenance technicians.

A medicine containing bamboo vinegar, chitosan and silver ions for treating dermatopathy, such as beriberi, is prepared through filtering bamboo, vigegar, adding the deacetylated chitosan, stirring for full dissolving, regulating pH=2.0-2.5, filtering, laying aside, adding the solution of silver nitrate, and stirring for 30 min. Its advantages are broad spectrum, high and durable curative effect, and high safety.

The present invention discloses a functional medicine preparation whose prescription is intensified by snake macro-micro elements necessary for human body for external application. It is characterized by that it utilizes percutaneous osmosis and adsorption to supplement trace elements to attain the goal of curing dermatosis. Its therapeutic effect is good and its cure rate is high.

Stable, anhydrous pharmaceutical compositions contain an organopolysiloxane elastomer and, as bioactive ingredient, at least one vitamin D compound in a solubilized form, and are useful for the topical treatment of psoriasis and other skin disorders / afflictions.

The present invention provides a pharmaceutical composition for treating skin disorders, including enhancing the healing of wounds for diabetic patients. Specifically, this invention relates to the use of the extracts of Plectranthus amboinicus and Centella asiatica for improving skin disorders, including enhancing the healing of wounds for diabetic patients, and a pharmaceutical composition comprising the extracts of Plectranthus amboinicus and Centella asiatica as well as a wound dressing comprising the same. The invention also provides a method for preparing the crude extract and extract of Plectranthus amboinicus.

A method and composition for the treatment of acne vulgaris, acne rosacea, and other inflammatory skin conditions comprises the oral administration of a composition comprising a dose of nicotinamide delivered at levels substantially in excess of normal dietary levels, the nicotinamide being delivered in combination with zinc. The composition may also include quantities of copper and folic acid. In a most preferred embodiment, the nicotinamide and copper each are present in immediate release formats, while the zinc is present in a sustained release format.

The invention provides a product for treating skin diseases caused by Malassezia, and medicines and daily chemical products of honokiol, wherein the product treats honokiol or its derivative as an active component; and the medicines and the daily chemical products are prepared through dispersing the honokiol or its derivative in medicine carriers. Above medicaments provided by the invention can effectively inhibit the breeding of the Malassezia, have the advantages of low toxicity and high medicine effect efficiency, and have wide application prospects.

The invention relates to a strengthened nanometer element traditional Chinese medicine anion functional perfume, belonging to the technical field of manufacturing enterprises for producing cosmetics and perfumes. The functional perfume such as ethanol perfume, floral water, sunscreen water and cologne are prepared by processing the traditional Chinese medicines such as Paris polyphylla, elecampane, radix gentianae, chrysanthemum, magnolia flower, natural mineral medicines as well as medical stone and tourmaline by a nano technology; the functional perfume is applied to the skin to be absorbed and penetrated to 3 to 5 mm under the skin. The functional perfume can be used for automatically heating up, activating tissues, prompting the metabolism, automatically and discontinuously generating the anion far infrared to effectively prompt the blood circulation, preventing and treating skin diseases, resisting the aging of skin, protecting the skin and beautifying.

The invention relates to an external traditional Chinese medicine preparation, namely a psoriasis paste. The psoriasis paste is prepared from traditional Chinese medicine oil, life kinetic hormones, vitamin E, mycose, allantoin, beewax, glycerinum and the like. Through clinical curative effect observation, the Fushukang ointment used for treating patients with skin diseases such as tinea capitis, tinea cruris, tinea of feet and hands, psoriasis, allergy, eczema and chilblain is remarkably in curative effect. The total effective rate is 96% in 100 cases observed.

A Chinese medicine for foot bath to treat fungal dermatopathy is prepared from 5-18 Chinese-medicinal materials including honeysuckle flower, aloe, borneol, coptis root, etc. Its preparing process is also disclosed.

The apparatus for non-invasive treatment of skin disorders or removal of unwanted hair comprises a reflector unit having therein at least one light source for emitting incoherent light, the reflector unit and the light source being replaceable after activation thereof and disposable after such replacement. The apparatus includes an energy source for providing an electrical current to the light source or light sources, an on / off switch for selectively triggering supply of the electrical current to the light source or light sources and preventing said current supply; and a controller for controlling at least one of the intensity, the pulse length and the sequence of each light source, at least one of the light sources being adapted to emit a series of light pulses.

Disclosed are devices, systems and methods that utilize bioprinters to form scaffold structures in situ to facilitate treatment of the musculoskeletal or skin disorders in patients. A method for treating a musculoskeletal disorder of a patient includes positioning a bioprinter at a situs of the musculoskeletal disorder, or a situs of a skin injury, in the patient. The method includes extruding a hydrogel formulation from the bioprinter into the situs. The method includes curing the hydrogel formulation in the situs. The hydrogel formulation has a composition effective to generate, upon the curing, a scaffold structure in the situs to facilitate muscle hypertrophy, or skin wound healing, in the situs.

Pro-apoptotic agents such as ligands and agonists of agonistic TRAIL receptors can induce or increase apoptosis of cells that cause fibrosis and underlying diseases such as liver, pancreatic, lung and skin diseases characterized by fibrosis, cirrhosis, or complications thereof. The compositions and methods can be used to selectively remove activated hepatic stellate cells (HSCs), the originators of liver fibrosis and cirrhosis, and activated pancreatic stellate cells (PSCs), the originators of pancreas fibrosis and pancreatitis, and can be effective to reduce or prevent further chronic fibrosis by simultaneously reducing multiple fibrosis-associated molecules secreted or induced by such activated stellate cells. The compositions are typically effective to target agonistic TRAIL receptors such as TRAIL-R1 / DR4 and TRAIL-R2 / DR5 that are selectively expressed in activated HSCs and PSCs in physiological conditions. Ligands and agonists that can be used to target agonistic TRAIL receptors include, but are not limited to, TRAIL-R1 / DR4 and / or TRAIL-R2 / DR5 agonists.

The invention provides a housefly larvae active protein peptide preparation method which includes the following steps: freezing of fresh housefly larvae, thawing, grinding, pH adjusting, extracting, centrifugal separation, ultrafiltration, nanofiltration desalination, concentration, filtration sterilization, freeze drying, product subpacking. The method has the advantages of simple operation and low production cost, is suitable for large-scale industrialized production, and can realize the purpose of efficient preparation of protein peptide from the housefly larvae. The invention also relates to housefly larvae active protein peptide obtained by the method, and the housefly larvae active protein peptide has significant skin regenerative repair functional activity to postburn patients. The invention also relates to the purpose of the housefly larvae active protein peptide obtained by the method, the use includes application of the housefly larvae active protein peptide in preparation of medicines, food, health care products or cosmetics for prevention and / or treatment of human traumatic skin disease.

The invention discloses an externally used compound preparation. The preparation comprises bioactive hyaluronic acid with anti-inflammatory activity, and also comprises an antimicrobial medicine or 8-50[mu]g / ml of cortical hormone, and the antimicrobial medicine is an antifungal agent and / or an antibacterial medicine. The bioactive hyaluronic acid with anti-inflammatory activity in the preparation substitutes all or most cortical hormone, and contains no or a small amount of the cortical hormone, so side effects brought by the cortical hormone are avoided or greatly reduced. The bioactive hyaluronic acid with anti-inflammatory activity can be compounded with the antifungal agent and / or the antibacterial medicine, so the preparation has antifungal and / or antibacterial curative effects, and can effectively treat gum, nasal mucosa and skin diseases.

The detoxicating and blood circulation promoting ointment is prepared with seven kinds of Chinese medicinal materials, including catechu, cordate houttuynia, yerbadetajo herb, brazil wood, gallnut, pricklyash root and menthol in certain weight proportion. The detoxicating and blood circulation promoting ointment is oil-in-water or water-in-oil emulsion preparation or water soluble gel applied directly onto the affected part. It has the functions of killing bacteria, diminishing inflammation, killing parasite, eliminating swelling, dissipating mass, etc. and is used in treating soft tissue injury, superficial burns and scalds, scabies, insect bite, arthritis and other diseases. It has fast and obvious treating effect, no toxic side effect, low cost and convenient use.

The invention concerns a methionine-derived peptidomimetic represented by the following general formula (II):R=X—C(O)—NH— with X=alkyl or alkyloxy (C1-C4); R′=HThe invention also concerns a composition for preventing or fighting cutaneous disorders associated to a mitochondrial dysfunction, and the use of a methionine-derived peptidomimetic as a cosmetic agent for protecting and / or stimulating the mitochondria of cutaneous cells.

The invention relates to a herbal composition for the treatment of psoriasis and other skin disorders. The herbal composition comprises the extracts of Psoralea corylifolia, Luffa acutangula, Rubia cordifolia, Boswellia serrata and Brassica nigra and oils of Azhadirachta indica, Linum usitatissum, Vitis vinifera, Brassica nigra, and Pongamia seed. The present invention further relates to cosmeceutical compositions comprising the said active agents, methods for preparing the composition and using the same in Psoriasis and other skin disorders in human beings. The methods of making the plant extract, methods for obtaining the topical preparation are disclosed.

The present invention relates to pharmaceutical compositions of activated botulinum holotoxin type B (150 kD). In particular, the present invention relates to botulinum toxin type B pharmaceutical compositions wherein at least 90% of said botulinum toxin type B is activated (i.e., “nicked”), and wherein at least 99% said nicked botulinum toxin type B is a 150 kD holotoxin (i.e., “stripped”). The invention also relates to a process of activating and stripping botulinum toxin type B wherein at least 90% of said botulinum toxin type B is nicked, and wherein at least 99% of said nicked botulinum toxin type B is stripped. The invention further relates to methods for the treatment of a variety of neuromuscular diseases, pain, inflammatory and cutaneous disorders comprising administering a pharmaceutical composition of activated botulinum holotoxin type B (150 kD) wherein at least 90% of said botulinum toxin type B is nicked, and wherein at least 99% of said nicked botulinum toxin type B is stripped.

The invention provides a complex, a tissue repair material, a preparation method of the tissue repair material and applications. The complex is stable in medicinal effect, high in targeting and high in transfer efficiency, and has good tolerance in vivo; and various biological functions can be achieved through endogenous matters, and immune response in vivo can be avoided. The tissue repair material has stable treatment effects and targeting on treating skin diseases, and especially has significant effects on treating diabetic complications which cannot be healed for a long time.

The invention relates to a traditional Chinese preparation, and particularly relates to an antibacterial and anti-inflammatory traditional Chinese medicine external preparation. The traditional Chinese medicine external preparation comprises the following specific formula in parts by weight: 20-32 parts of camphor oil, 20-32 parts of eucalyptus oil, 20-32 parts of selinum oil and 20-32 parts of hydnocarpus oil. The main dosage form of the traditional Chinese medicine external preparation is ointment, and the traditional Chinese medicine external preparation has wide applications in preparation of antibacterial and anti-inflammatory drugs as well as skin disease drugs. The traditional Chinese medicine external preparation has the advantages of rapidness in acting, high bacterium inhibitingrate, high clinical effective rate (98.24%), convenience in use, wide application range and no toxic or side effect.

The invention relates to a soluble microneedle patch for targeted diagnosis and treatment of skin diseases and preparation of the soluble microneedle patch, and belongs to the technical field of biological medicines. The patch comprises a base and polymer needle bodies, the polymer needle bodies are located on the base in an array mode, polymers forming the polymer needle bodies can be dissolved in water, and nano-drug particles are dispersed on the needle point parts of the polymer needle bodies. The preparation method comprises the following steps: treating a microneedle array female die by using oxygen plasma, so that the surface of the microneedle array female die is hydrophilic; and dripping the nano-drug solution on the surface of the microneedle array female die for centrifugal treatment, injecting the water-soluble polymer solution into the microneedle array female die, vacuumizing, drying, and stripping the microneedles from the female die to obtain the microneedle patch. The synthesized microneedle patch can realize real-time monitoring of metabolic behaviors of drug particles in skin disease treatment, and solves the technical problems of poor transdermal effect, uncontrollable drug metabolic behaviors, non-ideal curative effect and the like of transdermal drug delivery of nano-drugs in skin disease treatment.

The invention discloses the culturing, screening and amplification technology for keratinocytes. The bottlenecks are always hot spots and difficulty in biological cell field research. At present, separation and purification are conducted through basilar membrane significant adhesion characteristics, and the keratinocytes are obtained through a three-dimensional culturing and amplification means. The technology is suitable for depending on amplified anchorage-dependent cells and providing a three-dimensional high-simulation in-vivo cell extracellular matrix system for screening and separation of target cell levels. The in-vivo attachment environment is highly simulated, and a novel biological cell culturing technology for culturing adult (embryo skin) skin cells is provided. Adhering, screened and cultured target keratinocytes in the environment of high-simulation substrates have high passage capacity and multiplication capacity and can form a cortex structure under the in-vitro environment. Immunogenicity cells are screened out to safely obtain immune escape, transplanting time is prolonged, tissue engineering clinical application is improved, wound healing is promoted, skin diseases are treated, and a clinical treatment-grade cell solution with absolute advantages is provided.

The invention relates to an external medicament for treating skin diseases, and in particular relates to an external medicament. The medicament comprises the following drugs and medicinal matrixes or prepared from the following drugs and medicinal matrixes: cinnabar, calamine, borneol, frankincense, myrrh, rosin, castor oil, gypsum (sintered), camphor, calculus bovis factitius and pearl. The invention also relates to application of medicinal composition of the external medicament and a preparation method of the external medicament. The external medicament can be effectively used for treating skin diseases, such as whelk, pimples and acnes.

The embodiment of the invention provides a big data disease prediction system and disease prediction method based on 5G and blockchain, and aims to automatically realize disease prediction. The methodis applied to a server, a plurality of disease prediction models used for predicting different skin diseases are stored in the server, the multiple models are divided into multiple groups, and the multiple skin diseases predicted by each group of models have the same symptom. The disease prediction method comprises the following steps: receiving a focus image and text description of a disease symptom; generating a word vector according to the text description; comparing the word vector with respective sample word vectors of each group of disease prediction models so as to determine a sample word vector closest to the word vector; calling a group of disease prediction models corresponding to the sample word vector, and inputting the focus image into each disease prediction model in the group of disease prediction models to obtain a plurality of prediction results so as to determine a skin disease type; and feeding back the skin disease type to the user terminal.

The invention relates to an anion health preserving perspiration steaming vat. The anion health preserving perspiration steaming vat comprises a health preserving vat body and a fumigating and mixingdevice, wherein the health preserving vat body is connected with the fumigating and mixing device through a steam duct; the health preserving vat body and the fumigating and mixing device are connected with a power source control system; and the health preserving vat body comprises a vat body, a vat door, a ceramic bench and a base plate. According to the anion health preserving perspiration steaming vat disclosed by the invention, hydrosphere, oxygen and electromagnetization are comprehensively and integrally mixed; an oxygen increasing efflux unit rotates clockwise, and a steam current is incirculation rotation from bottom to top; a medicine adding hole is formed, liquid medicines mixed with hydrosphere and oxygen are subjected to electromagnetization, and enter the health preserving vat body to form micro cluster water of which the diameter is 0.5-0.8 nanometer, and then the micro cluster water enters the human body, so that various kinds of chronic diseases including skin diseases, joint diseases, hypertension, stroke sequela and the like can be effectively improved, and metabolism is enhanced; and the anion health preserving perspiration steaming vat can release anions, so that the excretion of metabolite is accelerated, and the metabolism of fat, uric acid and blood glucose is accelerated.

The invention relates to a use of ozonized oil in prevention and treatment on skin diseases, obesity and venous thrombus and combined use of the ozonized oil and drugs for treatment on skin diseases, obesity and venous thrombus. Burns, psoriasis, skin graft problems, obesity, phlebitis and venous thrombus can be effectively prevented and treated through the ozonized oil by means of oral administration, intraperitoneal injection, enema, gavage, intravenous injection, subcutaneous injection, intramuscular injection and suppository administration.

The present invention relates to a topical pharmaceutical preparation for treating an inflammatory skin condition, preferably a condition associated with ischemia, comprising a supernatant of a physiological solution obtainable by cultivating peripheral blood mononuclear cells (PBMCs) or a subset thereof in a physiological solution free of PBMC-prolif erating and PBMC-activating substances for at least 1 h.