127 results about "Cutaneous Disorders" patented technology

The present invention discloses a functional medicine preparation whose prescription is intensified by snake macro-micro elements necessary for human body for external application. It is characterized by that it utilizes percutaneous osmosis and adsorption to supplement trace elements to attain the goal of curing dermatosis. Its therapeutic effect is good and its cure rate is high.

The apparatus for non-invasive treatment of skin disorders or removal of unwanted hair comprises a reflector unit having therein at least one light source for emitting incoherent light, the reflector unit and the light source being replaceable after activation thereof and disposable after such replacement. The apparatus includes an energy source for providing an electrical current to the light source or light sources, an on/off switch for selectively triggering supply of the electrical current to the light source or light sources and preventing said current supply; and a controller for controlling at least one of the intensity, the pulse length and the sequence of each light source, at least one of the light sources being adapted to emit a series of light pulses.

Pro-apoptotic agents such as ligands and agonists of agonistic TRAIL receptors can induce or increase apoptosis of cells that cause fibrosis and underlying diseases such as liver, pancreatic, lung and skin diseases characterized by fibrosis, cirrhosis, or complications thereof. The compositions and methods can be used to selectively remove activated hepatic stellate cells (HSCs), the originators of liver fibrosis and cirrhosis, and activated pancreatic stellate cells (PSCs), the originators of pancreas fibrosis and pancreatitis, and can be effective to reduce or prevent further chronic fibrosis by simultaneously reducing multiple fibrosis-associated molecules secreted or induced by such activated stellate cells. The compositions are typically effective to target agonistic TRAIL receptors such as TRAIL-R1/DR4 and TRAIL-R2/DR5 that are selectively expressed in activated HSCs and PSCs in physiological conditions. Ligands and agonists that can be used to target agonistic TRAIL receptors include, but are not limited to, TRAIL-R1/DR4 and/or TRAIL-R2/DR5 agonists.

The invention discloses an externally used compound preparation. The preparation comprises bioactive hyaluronic acid with anti-inflammatory activity, and also comprises an antimicrobial medicine or 8-50[mu]g/ml of cortical hormone, and the antimicrobial medicine is an antifungal agent and/or an antibacterial medicine. The bioactive hyaluronic acid with anti-inflammatory activity in the preparation substitutes all or most cortical hormone, and contains no or a small amount of the cortical hormone, so side effects brought by the cortical hormone are avoided or greatly reduced. The bioactive hyaluronic acid with anti-inflammatory activity can be compounded with the antifungal agent and/or the antibacterial medicine, so the preparation has antifungal and/or antibacterial curative effects, and can effectively treat gum, nasal mucosa and skin diseases.

The detoxicating and blood circulation promoting ointment is prepared with seven kinds of Chinese medicinal materials, including catechu, cordate houttuynia, yerbadetajo herb, brazil wood, gallnut, pricklyash root and menthol in certain weight proportion. The detoxicating and blood circulation promoting ointment is oil-in-water or water-in-oil emulsion preparation or water soluble gel applied directly onto the affected part. It has the functions of killing bacteria, diminishing inflammation, killing parasite, eliminating swelling, dissipating mass, etc. and is used in treating soft tissue injury, superficial burns and scalds, scabies, insect bite, arthritis and other diseases. It has fast and obvious treating effect, no toxic side effect, low cost and convenient use.

The invention concerns a methionine-derived peptidomimetic represented by the following general formula (II):

The invention also concerns a composition for preventing or fighting cutaneous disorders associated to a mitochondrial dysfunction, and the use of a methionine-derived peptidomimetic as a cosmetic agent for protecting and/or stimulating the mitochondria of cutaneous cells.

The present invention relates to pharmaceutical compositions of activated botulinum holotoxin type B (150 kD). In particular, the present invention relates to botulinum toxin type B pharmaceutical compositions wherein at least 90% of said botulinum toxin type B is activated (i.e., “nicked”), and wherein at least 99% said nicked botulinum toxin type B is a 150 kD holotoxin (i.e., “stripped”). The invention also relates to a process of activating and stripping botulinum toxin type B wherein at least 90% of said botulinum toxin type B is nicked, and wherein at least 99% of said nicked botulinum toxin type B is stripped. The invention further relates to methods for the treatment of a variety of neuromuscular diseases, pain, inflammatory and cutaneous disorders comprising administering a pharmaceutical composition of activated botulinum holotoxin type B (150 kD) wherein at least 90% of said botulinum toxin type B is nicked, and wherein at least 99% of said nicked botulinum toxin type B is stripped.

The invention provides a complex, a tissue repair material, a preparation method of the tissue repair material and applications. The complex is stable in medicinal effect, high in targeting and high in transfer efficiency, and has good tolerance in vivo; and various biological functions can be achieved through endogenous matters, and immune response in vivo can be avoided. The tissue repair material has stable treatment effects and targeting on treating skin diseases, and especially has significant effects on treating diabetic complications which cannot be healed for a long time.

The invention relates to a traditional Chinese preparation, and particularly relates to an antibacterial and anti-inflammatory traditional Chinese medicine external preparation. The traditional Chinese medicine external preparation comprises the following specific formula in parts by weight: 20-32 parts of camphor oil, 20-32 parts of eucalyptus oil, 20-32 parts of selinum oil and 20-32 parts of hydnocarpus oil. The main dosage form of the traditional Chinese medicine external preparation is ointment, and the traditional Chinese medicine external preparation has wide applications in preparation of antibacterial and anti-inflammatory drugs as well as skin disease drugs. The traditional Chinese medicine external preparation has the advantages of rapidness in acting, high bacterium inhibitingrate, high clinical effective rate (98.24%), convenience in use, wide application range and no toxic or side effect.

The invention relates to an external medicament for treating skin diseases, and in particular relates to an external medicament. The medicament comprises the following drugs and medicinal matrixes or prepared from the following drugs and medicinal matrixes: cinnabar, calamine, borneol, frankincense, myrrh, rosin, castor oil, gypsum (sintered), camphor, calculus bovis factitius and pearl. The invention also relates to application of medicinal composition of the external medicament and a preparation method of the external medicament. The external medicament can be effectively used for treating skin diseases, such as whelk, pimples and acnes.

The invention relates to an anion health preserving perspiration steaming vat. The anion health preserving perspiration steaming vat comprises a health preserving vat body and a fumigating and mixingdevice, wherein the health preserving vat body is connected with the fumigating and mixing device through a steam duct; the health preserving vat body and the fumigating and mixing device are connected with a power source control system; and the health preserving vat body comprises a vat body, a vat door, a ceramic bench and a base plate. According to the anion health preserving perspiration steaming vat disclosed by the invention, hydrosphere, oxygen and electromagnetization are comprehensively and integrally mixed; an oxygen increasing efflux unit rotates clockwise, and a steam current is incirculation rotation from bottom to top; a medicine adding hole is formed, liquid medicines mixed with hydrosphere and oxygen are subjected to electromagnetization, and enter the health preserving vat body to form micro cluster water of which the diameter is 0.5-0.8 nanometer, and then the micro cluster water enters the human body, so that various kinds of chronic diseases including skin diseases, joint diseases, hypertension, stroke sequela and the like can be effectively improved, and metabolism is enhanced; and the anion health preserving perspiration steaming vat can release anions, so that the excretion of metabolite is accelerated, and the metabolism of fat, uric acid and blood glucose is accelerated.

The invention relates to a use of ozonized oil in prevention and treatment on skin diseases, obesity and venous thrombus and combined use of the ozonized oil and drugs for treatment on skin diseases, obesity and venous thrombus. Burns, psoriasis, skin graft problems, obesity, phlebitis and venous thrombus can be effectively prevented and treated through the ozonized oil by means of oral administration, intraperitoneal injection, enema, gavage, intravenous injection, subcutaneous injection, intramuscular injection and suppository administration.

The present invention relates to a topical pharmaceutical preparation for treating an inflammatory skin condition, preferably a condition associated with ischemia, comprising a supernatant of a physiological solution obtainable by cultivating peripheral blood mononuclear cells (PBMCs) or a subset thereof in a physiological solution free of PBMC-prolif erating and PBMC-activating substances for at least 1 h.

The invention discloses a traditional Chinese medicine composition for treating the diseases of the bone, the joint, gastroenteropathy and the skin and a preparation method thereof. The traditional Chinese medicine composition comprises the following components: 1-10 parts of borneol, 1-10 parts of eucalyptus oil and 1-10 parts of clove oil; by oral administration, the traditional Chinese medicine composition has the effects of dredging the orifices, inducing resuscitation, reducing fever, removing toxicity, diminishing inflammation, decreasing swelling, promoting blood circulation, relieving the stasis of blood, promoting blood circulation, invigorating pulse-beat, promoting the blood circulation and the microcirculation of a human body, reinforcing the immunity of the human body and the like, can suppress or eliminate the exudation, the swelling and the swelling of the blood bud of the synovial membrane of the non-specific inflammatory algogenic substances of the position of the joint of the bone and the hyperosteogeny of the position of the joint of the bone, reinforces the activity of various histiocytes of the whole body and reinforces the immunological function and the humoral immunity of the human body and the capabilities of disease prevention and disease resistance of an organism, so that the traditional Chinese medicine composition has the stronger functions of treatment and immunological regulation. By external application, the traditional Chinese medicine composition has stronger functions of resisting bacteria, sterilizing, removing necrotic tissue, alleviating pain, relieving itching, diminishing inflammation and preventing decay. The traditional Chinese medicine composition can effectively treat various diseases of the bone, the joint and the skin and has obvious clinical curative effect and good application safety.

Medicaments or cosmetic compositions for the treatment or alleviation of skin or mucous membrane diseases or disorders related to an enhanced level of anti-microbial peptides or proteins comprising Tambourissa plant extracts, which may comprise polyphenols.