41 results about "Condyloma acuminata" patented technology

The invention discloses a composite capable of preventing bacteria, viruses, oxidation and pigment deposition, which is characterized by being prepared from the following raw materials in proportion by weight: 0.1-10 of epigallocatechin gallate (EGCG), 0-10 of chlorogenic acid, 0-10 of asiaticoside and 0-10 of ginkgolide. The invention also discloses application of the composite in preparing drugs, health-care food and cosmetics, which are capable of preventing bacteria, viruses, oxidation and pigment deposition. The composite of the invention has favorable safety, is suitable for curing respiratory tract infection, condyloma acuminatum, herpes progenitalis, chromatosis and other diseases, simultaneously has anti-oxidation and skin whitening functions, protects cells and DNA from being damaged, can prevent and cure dementia and chloasma, and also can be used for cancer adjuvant therapy.

A plural gel is composed of 5-aminolevulinic acid compound, hyaluronic acid, poloxamer and deionized water and used for assisting in treatment of acne, condyloma acuminata and other hyperproliferative skin diseases by means of a photon therapeutic device. The plural gel has light guiding and heat insulating effects, can prevent scalding, drying, chapping, wrinkling and freckling of skin, and can protect skin and accelerate healing of an affected part.

The invention discloses a podophyllotoxin preparation formula for external use for the treatment of condyloma acuminatum and genital herpes, a series of formulations and a preparation method, and belongs to the field of pharmacy. The weights or the volumes of all the ingredients of the formula of 100ml of the podophyllotoxin preparation for external use are as follows: 0.5g of podophyllotoxin, 20ml-80ml of main solvent, 1ml-3ml of penetration enhancer 1, 0.5g-2.5g of penetration enhancer 2, 20ml-80ml of cosolvent and 0.03-0.5g of preservative. The podophyllotoxin preparation for external use has the advantages that the types and the amount of excipients and the proportion of main drugs are reasonable, the drug administration is carried out by a liniment, a spray or other formulations which are applicable to the external use, the main drug can be rapidly absorbed by the horny layer and the epidermis, the efficacy is significant, the local toxicity or side effects are small, the skin acute toxicity is very low, and the podophyllotoxin preparation has no irritation and weak allergy and does not hinder the skin normal functions; the podophyllotoxin preparation has no systemic toxicity or side effects, thereby being safe and effective. The preparation prepared by the formula has the advantages of good appearance, moderate viscosity, easy coating, spraying drug administration, feasible process, controllable quality, simple preparation process, and suitability for industrial batch production.

The invention provides application of linoleic acid in preparing a human papillomavirus resisting (HPV) medicament. In the application, the linoleic acid can be a soluble solution prepared by using linoleic acid, or an extract extracted from natural plants. The linoleic acid has trend of inhibiting Hacat cell multiplication, and the inhibiting trend of the linoleic acid increases along with extension of the acting time of the medicament. Polymerase chain reaction experiments and cytological experiments prove that the linoleic acid has HPV resistance, and plays a role in treating condyloma acuminata (CA).

The invention relates to a diphenyltetrahydroporphin compound, a preparation method and application thereof. The compound has the following structure (I) which is shown in the description, wherein R1and R2 are positioned at the ortho-position (o-), meta-position (m-) or para-position (p-) of a benzene ring; R1 is -H or -OMe; R2 is -OCH2COOH or -OCH2CH2CH2COOH. The invention relates to the fieldsof photosensitive drugs (also called as a photosensitizer or photodynamic drug) and photodynamic therapy, and particularly relates to a diphenyltetrahydroporphin photosensitizer, a preparation methodand application in the field of medicines. The diphenyltetrahydroporphin compound prepared by the method provided by the inventionvis stable in chemical property, has strong photodynamic activity, andcan be used as a drug for photodynamic diagnosis and treatment of diseases such as tumors, macula-retinae degeneration, actinic keratosis, nevus flammeus and condyloma acuminata and the like.

The invention relates to a diphenyldihydroporphin compound, a preparation method and application thereof. The compound has the following structure (I) which is shown in the description, wherein R1 andR2 are positioned at the ortho-position (o-), meta-position (m-) or para-position (p-) of a benzene ring; R1 is -H or -OMe; R2 is -OCH2COOH or -OCH2CH2CH2COOH. The invention relates to the fields ofphotosensitive drugs (also called as a photosensitizer or photodynamic drug) and photodynamic therapy, and particularly relates to a diphenyldihydroporphin photosensitizer, a preparation method and application in the field of medicines. The diphenyldihydroporphin compound prepared by the method provided by the invention is stable in chemical property, has strong photodynamic activity, and can be used as a drug for photodynamic diagnosis and treatment of diseases such as tumors, macula-retinae degeneration, actinic keratosis, nevus flammeus and condyloma acuminata and the like.

The invention discloses a traditional Chinese medicine aqueous solution for treating condyloma acuminata and preventing relapse. The traditional Chinese medicine is prepared from, by weight, 8-9 partsof honeysuckle flowers, 10-12 parts of dandelions, 5-8 parts of radix sophorae flavescentis, 10-11 parts of herba portulacae, 3-5 parts of milkvetch roots, 5-7 parts of hedyotis diffusa, 5-8 parts ofamur cork tree bark, 7-9 parts of isatis roots, 3-5 parts of radices lithospermi, 4-6 parts of coix seeds, 1-3 parts of bighead atractylodes rhizomes, 10-20 parts of an embedding carrier and 2-3 parts of goose fat. The embedding carrier is prepared by compounding the raw materials of soya bean lecithin, leucine zipper peptide and glycerin trioleate. A preparation method of the traditional Chinesemedicine aqueous solution includes the following steps of 1, extraction of the medicine effective components; S2, preparation of the embedding carrier; S3, medicine carrying, wherein 10-20 parts of the embedding carrier prepared in S2 and mixed liquid medicine extracted in S1 are incubated under the condition of 55 DEG C for 1 h, the traditional Chinese medicine components are embedded into the carrier, and the traditional Chinese medicine aqueous solution for treating condyloma acuminata and preventing relapse is obtained. The traditional Chinese medicine aqueous solution has a more durablemedicine effect for treating condyloma acuminata and a complete treatment effect, and is free of toxic and side effects and low in relapse rate.

The present invention relates to condyloma acuminate treating Chinese herbal medicine, and is especially a kind of fumigant for treating condyloma acuminate. The fumigant is prepared with isatis root, flavescent sophora root, windpipe trachea, rhubarb, purslane and other eight kinds of Chinese medicinal materials in certain weight proportion. The present invention has the features of convenient treatment, low cost, fast acting, no irritation and no side effect.

The invention relates to a novel porphin diether salt compound (I) as well as a preparation method and application thereof. The compound (namely, porphin diether disodium salt, porphin diether dimethyl salt, porphin diether dilithio salt and porphin diether diammonium salt compound) has a structure shown in the description. The compound provided by the invention has the advantages of single component, stable property, controllable quality, simple and convenient preparation method and high water solubility, and can be easily prepared into an injection or a freeze-drying preparation. The compound has remarkable photodynamic activity, and can be applied to photodynamic therapy of tumors, retina macular degeneration, actinic keratosis, nevus flammeus, verruca acuminate and the like.

The invention belongs to the field of a medicine, relating to ointment for treating condyloma acuminatum, which contains the following components by mass: 3-40 parts of brucea javanica oil, 0.1-10 parts of aqueous matrix, 3-40 parts of emulsifier and 10-93.9 parts of water. The ointment disclosed by the invention is a new, non-toxic and harmless prescribed pure traditional Chinese medicine preparation which is free from untoward effects. The pharmacology and the clinical practice confirm that the ointment has the effects of removing putrid tissues and regenerating tissues, and promoting the necrotic tissues to liquefy, decompose and fall off, so that the condyloma acuminatum can be treated as soon as possible, the patients can avoid the surgical pain, other equipments are not needed, and the economic consumption of the patients is reduced as well. The ointment is safer, more effective and convenient to use. Simultaneously, the treatment effect of the ointment is identical to that of the current brucea javanica oil compound preparation by optimizing the prescription and the preparation technology, and the cost is lower, and the preparation technology is more convenient.

The invention relates to a tetraphenylmethylene chlorin compound, and a preparation method and application thereof. The tetraphenylmethylene chlorin compound has a following structure (I) as shown in the description, wherein R1 and R2 located in ortho-positions (o-), meta-positions (m-) or para-positions (p-) of a benzene ring. The invention relates to the field of photosensitive drugs (also named photosensitizers or photodynamic sensitizers) and photodynamic therapy, and in particular to methylene chlorin photosensitizer, and the preparation method and the application thereof in the field of medicine. The tetraphenylmethylene chlorin photosensitizer prepared by the invention has stable chemical property and very strong photodynamic activity and can be used for photodynamic therapy of diseases of tumors, retina macular degeneration, actinic keratoma, nevus flammeus, condyloma acuminata and the like.

The invention discloses bacteriostatic care lotion and a preparation method thereof, belongs to the technical field of cleaning and care products, particularly relates to the technical field of external bacteriostatic care lotion, and aims to solve the problems of large dosage, long treatment course, low curative effect, significant side effect and high recurrence rate in the existing treatment of infectious skin diseases. The bacteriostatic care lotion comprises the following components in parts by weight: 10-23 parts of traditional Chinese medicine extracting solution. The traditional Chinese medicine extracting solution is prepared from the following traditional Chinese medicinal materials: flos lonicerae, herba taraxaci, herba violae, cortex dictamni, cortex phellodendri, rhizoma coptidis, fructus gardeniae, radix scutellariae, herba artemisiae scopariae, radix sophorae flavescentis, rhizoma atractylodis, radix angelicae pubescentis, rhizoma acori graminei, cortex pseudolaricis, fructus cnidii, fructus kochiae, brucea javanica, pheretima, periostracum serpentis, dried alum, mint, folium artemisiae argyi and radix glycyrrhizae. The bacteriostatic care lotion can be used for treating condyloma acuminatum, colpitis mycotica and trichomonas vaginitis at the same time, does not damage liver and kidney functions after being used for a long time, and is quick in action and low in recurrence rate.

The invention relates to an external agent for treating flat wart and pointed condyloma and making method belonging in medicine technology field and which is used for solving the problem that the flat wart and the pointed condyloma are difficult to cure, wherein the composition includes the following weight unit raw material: 10-50 brucea fruit, 10-40 burning bush peel, 10-40 agastache. The external agent can be produced basing the said pharmaceutical through batching, disintegrating, infusing with alcohol, filtering and deslagging, which is characterized by the following: basing on traditional Chinese medicine theory and result of clinic experience over many years to treat with main purpose of detoxication and remove stasis, reducing fever and chilling blood; refining the brucea fruit, burning bush peel and agastache to infuse with alcohol to apply on affected part after squeezing; observing the flat wart to disappear and dune skin at the same time about 10 days later with no-recurrence and 90% curing rate. The invention has better treating effect to the pointed condyloma, which has merits of simple method, fast showing effect, no bitter during treating process and not having colored trace after cure.

A vagina-cleaning sanitary lotion is prepared from following pharmaceutical components: 15 parts of polyhexamethylen guanidine hydrochloride, 15 parts of Stigma Croci, 15 parts of glycerol, 10 parts of Rhizoma Gastrodiae, 10 parts of Pericarpium Zanthoxyli, 10 parts of Radix seu Folium Abelmoschi Moschat, 10 parts of rosemary essential oil, 8 parts of menthol, 13 parts of Radix Angelicae Sinensis, 13 parts of diphenhydramine, and 80 parts of purified water. The vagina-cleaning sanitary lotion is effective in killing germs and viruses on whole body skin mucosa, better in effect of killing infective germs, fungi and viruses on skin and mucosa of private parts of adult male and female, is capable of killing germs, fungi, Neisseria gonorrhoeae, human papilloma virus and human immunodeficiency virus, and is effective in preventing female bacterial vaginosis, fungal vaginitis, male and female gonorrhea, condyloma acuminata, acquired immune deficiency syndrome and the like.

The invention relates to a novel water-soluble intermediate di (disubstituted amino) phenyl porphin tetrapyrrole compound which is good in hydrophilicity, easy to prepare into an injection and simple and feasible in preparation process, and a preparation method of the tetrapyrrole compound shown in the description, wherein X is H, Cl, Br, or I; R is a meta-position or para-position group, and R is -N (R1) 2; R1 is -(CH2)nCOOH, and n is equal to 1-6; and R2 is 2H or Zn. The invention relates to the field of photosensitive drugs and photodynamic therapy, in particular to a novel intermediate di (disubstituted amino) phenyl porphin tetrapyrrole compound which is good in hydrophilicity and easy to prepare into injection, a preparation method of the intermediate di (disubstituted amino) phenyl porphin tetrapyrrole compound and application of the intermediate di (disubstituted amino) phenyl porphin tetrapyrrole compound in the field of medicine. The intermediate di (disubstituted amino) phenyl porphin photosensitizer prepared by the invention has remarkable photodynamic activity and low skin light toxic and side effects, and can be used as a drug for photodynamic diagnosis and treatment of diseases such as tumors, retina macular degeneration, actinic keratosis, nevus flammeus and condyloma acuminata.

The invention relates to a preparation method of a podophyllotoxin transdermal drug delivery preparation; the water solubility and the stability of podophyllotoxin can be effectively improved, and skin irritation can be relieved; according to the prescription of the prepared preparation, each 100g of the prescription consists of the following ingredients by mass: 0.1-10g of carboxylic carbon nanotube loaded podophyllotoxin, 1-5g of carbomer, 5-15g of glycerol, 3-6g of azone, 0.1-0.5g of triethanolamine and 80-85g of pure water. The transdermal drug delivery preparation disclosed by the invention has the advantages that the carboxylic carbon nanotube, which is loaded with the podophyllotoxin, is prepared into a gel, and compared with a podophyllotoxin gel, the stability of the podophyllotoxin is enhanced, a skin penetration rate is relatively low and an amount retained in skin is increased, so that the curative effect on condyloma acuminate is enhanced, adverse reactions such as the skin irritation and the like are reduced, and toxic and side reactions in a whole body are reduced. The transdermal drug delivery preparation disclosed by the invention is simple in preparation process, controllable in quality, good in stability and suitable for mass production; therefore, a novel dosage form is provided for clinical administration.