99 results about "Gonorrhea" patented technology

Said invention relates to a nano antibiotic intelligent heat storage fiber and preparation and use thereof, which is composed of polypropylene, polyester, polyamide, polycarylonitrile and viscose fiber wherein the nano antibiotic intelligent heat storage function powder of 0.5-4 % of total fiber weight is uniformly distributed in fiber and surface layer. Said invention can absorb visible light source and convert into heat energy, also can absorb human body heat and store in fiber fabric then warm human body. Said invention has bacteriostasis and antibiotic effect to colibacillus, candida albicans, staphylococcus, gonorrhea, hepatitis etc.

The invention discloses a traditional Chinese medicine combination for curing visceral inflammation of human bodies. The raw materials which are prepared into the active components comprise melastoma dodecandrum lour, garden burnet, lobelia chinensis, honeysuckle, isatis root, rhizome anemarrhenae, Chinese thorowax root, pomegranate rind, plantain, Chinese caterpillar fungus, licorice root, Corsvenor momordica fruit, codonopsis, Chinese wolfberry, radix ginseng rubra and white ginseng. The combination has effect in invigorating the lung and reinforcing kidney, replenishing Qi and invigorating the spleen, greatly nourishing vital energy, cleaning heat, purging fire and removing toxins, generating saliva and moisturizing dryness, cooling blood and relieving sore throat, promoting urination and detumescence, moisturizing the lung, dredging the pulse vessel and removing fever, soothing the liver, and the like, has better functions of preventing and curing various visceral inflammations of human bodies, has particular efficacy to cure the diseases, like virus hepatitis, typhoid, nephritis and pneumonia and has certain effect in curing diseases, like swells in the loin, lumbodynia, diarrhea, hematochezia, dysentery, gonorrhea, diabetes, various types of gynecopathy, reddish swelling, chicken pox, cough, cold and fever.

The present invention provides a method of inhibiting the formation of infectious herpes virus particles, particularly infectious herpes simplex virus (HSV) particles, in a host cell. The method involves administering an effective amount of a hydroxylated tolan, particularly a polyhydroxylated tolan, to a herpes virus infected host cell. The present invention also provides a method of treating a herpes virus infection, particularly an HSV infection. The method comprises administering a topical composition comprising a therapeutically effective amount of a hydroxylated tolan to a herpes virus-infected site. The present invention also relates to a topical composition for treating a herpes virus infection selected from the group consisting of an HSV infection, a cytomegalovirus infection, and a varicella zoster virus infection. The present invention also provides a method of treating a subject infected with Neisseria gonorrhea.

The present invention relates to oligonucleotide sequences for amplification primers and detection probes and to their use in nucleic acid amplification methods for the selective and specific detection of Chlamydia trachomatis in biological samples. The invention also provides oligonucleotide primer sets and primer / probe sets in the form of kits for the detection and diagnosis of chlamydial infection. The inventive oligonucleotide primers and probes can also be used in combination with other specific oligonucleotide primers and probes for the simultaneous detection ofChlamydia trachomatis and other target organisms, such as Neisseria gonorrhea.

The invention relates to a ceftizoxime sodium crystalline hydrate and a preparation method and application thereof. The ceftizoxime sodium crystalline hydrate has high storage stability, and is suitable for preparing medicaments for treating or preventing diseases such as infection of respiratory systems, liver and biliary systems, five sense organs and urinary tracts of human bodes or animals, infection of abdominal cavity, infection of pelvic cavity, ichorrhemia, infection of skin tissues, and infection of bones and joint caused by gram positive or negative bacteria, meningitis caused by streptococcus pneumonia or haemophilus influenza, and simple gonorrhea.

The invention discloses a cefuroxime sodium compound entity which is relatively poor in hygroscopicity, relatively good in storage stability and applicable to preparation of drugs for treating or preventing respiratory system infection, five-organ infection, urinary system infection, pelvic cavity infection, septicemia, skin soft-tissue infection, bone and joint infection, gonorrhea and meningitis of human or animals, caused by sensitive gram positive or negative bacteria.

The invention relates to a marine organism degerming air refresher. Its active ingredients, which contain a chitosan quaternized hyaluronic acid derivative, an algal polysaccharide derivative, marine organism alpha-spiral cecropin and biological enzyme, polyhexamethylene guanidine and a plant essence, are prepared into the marine organism degerming air refresher by a special technology. The marine organism degerming air refresher is applicable to be used in environments such as restaurants, hotels, hospitals, markets, banks, schools, homes, offices, automobiles and the like, can be used to effectively remove peculiar smell in a closed environment, kill bacteria in the air and control the spread of typhoid, influenza, dysentery, pinkeye, gonorrhea and various skin diseases, and will not stimulate and corrode object surface, skin and respiratory tract. The formula of a marine organism active element bacteria-removing liquid contains the following components of: by weight, 0.5-1.5% of the chitosan quaternized hyaluronic acid derivative; 0.5-1.0% of the algal polysaccharide derivative; 4.0-6.0% of the marine organism alpha-spiral cecropin; 1.5-3.0% of polyhexamethylene guanidine; a proper amount of the plant essence; and purified water added to 100%.

The invention provides a cefoperazone sodium compound entity and a composition thereof. The cefoperazone sodium compound entity is low in hygroscopicity and good in storage stability, is suitable in an application of preparing drugs for treating or preventing respiratory system infection, infection in the five sense organs, urinary system infection, pelvic cavity infection, septicemia, skin soft tissue infection, infection in bones and joints, gonorrhea and meningitis of human or animal due to bacteria being sensitive to gram-positive bacteria or gram-negative bacteria.

The invention relates to a cefonicid sodium hydrate and a preparation method and application thereof. The cefonicid sodium hydrate has better storage stability and is applicable to preparation of the medicaments for treating or preventing such diseases caused by gram positive or negative sensitive bacteria as respiratory system infection, hepatobiliary system infection, five sense infection, urinary tract infection, abdominal infection, pelvic infection, sepsis, skin soft tissue infection, bone and joint infections, annexitis, intrauterine infection, parametritis, meningitis, gonorrhea and the like of human or animals.

The invention discloses a urethral clearing agent and a preparation method thereof. The urethral clearing agent comprises the following mixed extracts of prescription medicines in parts by weight: 80-160 parts of rhizoma dioscoreae hypoglaucae, 40-80 parts of golden cypress, 80-160 parts of Chinese violet, 80-160 parts of dandelion, 120-240 parts of semen coicis, 40-80 parts of tuckahoe, 40-80 parts of moutan bark, 40-80 parts of rhizoma alismatis, 60-120 parts of talcum powder, 60-120 parts of semen plantaginis, 40-80 parts of umbellate pore fungus and 40-80 parts of phoenix-tail fern. The preparation method comprises the following steps: concentrating a leach liquor into thick paste after leaching a prescription by using hot water, and then leaching by using ethanol. The urethral clearing agent has significant treatment effects on patients with damp and hot accumulate resistance such as non-gonococcal urethritis caused by infection of chlamydia, mycoplasma and the like, gonorrhea, prostatitis, impotence and the like by the synergistic effects of effective components in each component in the prescription. The preparation method adopts a mature controlled pharmaceutical technology to process, and the traditional Chinese medicine components in the prescription are effectively obtained, so that the drug is table and reliable in properties.

A Chinese medicine for treating dermatopathy and venereal disease, including eczema, tinea, vulvitis, pointed condyloma, gonorrhea, syphilis etc is prepared from Chinese-medicinal materials including pearl, calomel, realgar, etc through pulverizing and mixing with vasuline. Its advantages are high curative effect, quickly taking its effect, no by-effect and no recurrence.

Provided are non-competitive internal controls for use in nucleic acid tests (NATs), which are obtained from the organisms Methanobacterium thermoautrophicum (MET) and Zea mays (Corn). The non-competitive internal controls have utility in DNA and RNA NATs selected from Influenza A, Influenza B, parainfluenza viruses 1 to 4 (PIV-1 to PIV-4), respiratory syncytial virus type A (RSV A), RSV B, human metapneumovirus (hMPV), Chlamydia trachomatis (CT), and Neisseria gonorrhea (GC), Hepatitis B virus (HBV), Hepatitis C virus (HCV), Human Immunodeficiency Virus I (HIV-1), and Severe Acute Respiratory Syndrome (SARS).

The present invention provides a method of inhibiting the formation of pseudorabies particles in a host cell. The method involves administering an effective amount of a poly-hydroxylated stilbene, particularly resveratrol, to a herpes virus infected host cell. The present invention also provides a method of reducing or inhibiting the growth of Neisseria gonorrhea and Neisseria meningiditis in vitro and in vivo. The method comprises administering a composition comprising a therapeutically effective amount of a tri-hydroxylated stilbene to a growth surface which has come into contact or could come into contact with the bacterium.

Provided are non-competitive internal controls for use in nucleic acid tests (NATs), which are obtained from the organisms Methanobacterium thermoautrophicum (MET) and Zea mays (Corn). The non-competitive internal controls have utility in DNA and RNA NATs selected from Influenza A, Influenza B, parainfluenza viruses 1 to 4 (PIV-1 to PIV-4), respiratory syncytial virus type A (RSV A), RSV B, human metapneumovirus (hMPV), Chlamydia trachomatis (CT), and Neisseria gonorrhea (GC), Hepatitis B virus (HBV), Hepatitis C virus (HCV), Human Immunodeficiency Virus I (HIV-1), and Severe Acute Respiratory Syndrome (SARS).

The invention discloses a production method of a phellinus igniarius mycelia product containing rich bioactive substances. The production method comprises the following steps: inoculating phellinus igniarius mycelia in a culture medium using mulberry stalks as raw materials, inducing the mycelia to change color in combination with the temperature and the illumination time, omitting a fruiting body formation stage, and culturing the mature mycelia product containing rich effective substances of polysaccharides, flavones, triterpenes, beta-sitosterol and alkaloids by a dry or wet separation process. The phellinus igniarius mycelia product cultured by the method is a green organic product with a healthcare function, has the effects of benefiting the five internal organs, softening hard mass, removing toxic materials, stopping bleeding, activating blood, harmonizing the stomach and relieving diarrhea, and is used for mainly treating gonorrhea, metrorrhagia, metrostaxis, morbid leucorrhea, abdominal mass accumulation, hypochondrium fluid retention and splenasthenic diarrhea; the effects of the phellinus igniarius mycelia product are not poorer than those of cordyceps sinensis.

The invention relates to a kit for rapidly detecting chlamydia trachomatis and gonorrhea and an application of the kit and belongs to the field of medical detection. Specifically, the kit is a test paper card formed by assembling a processed sample pad, a binding pad, a nitrocellulose membrane and a water absorption pad which are in sequential overlap joint on a PVC (printed circuit board), wherein the a rare earth fluorescent microsphere labeled antibody is adsorbed on the binding pad and the nitrocellulose membrane is coated with a detection line and a quality control line.

The present invention relates to oligonucleotide sequences for amplification primers and detection probes and to their use in nucleic acid amplification methods for the selective and specific detection of Chlamydia trachomatis in biological samples. The invention also provides oligonucleotide primer sets and primer / probe sets in the form of kits for the detection and diagnosis of chlamydial infection. The inventive oligonucleotide primers and probes can also be used in combination with other specific oligonucleotide primers and probes for the simultaneous detection of Chlamydia trachomatis and other target organisms, such as Neisseria gonorrhea.

The disclosure relates to novel probes for use in LAMP detection methods. The probes contain a single fluorophore label bound to an internal cytosine residue of the probe. The probes are particularly useful in the detection of chlamydia and gonorrhea infections in a patient.

The invention relates to an egg yolk culture medium for amino acid neutralization, in particular to a prescription of a culture medium used when a gonorrhea patient need the gonococcus culture examination after using a large amount of clinical antibiotics and a preparation method of the culture medium. The gonococcus culture examine is an important method used for diagnosing gonorrhea. The purulent inflammation which is the disease of genitourinary system and caused by gonococcus is one of the pathogens to which clinical doctors attach importance. Especially when the large amount of clinical antibiotics is used, the gonococcus detection is very difficult because a sample contains a large amount of residual antibiotics, and the recovered gonococcus culture is still influenced by the residual antibiotics, therefore the design mistake of not adopting an experiment for removing the residual antibiotics is very serious, and the result obtained by the experiment is not reliable. The invention aims to provides an egg yolk culture medium for amino acid neutralization, which is used for clinically judging the gonococcus used in the sample of a genitourinary tract.

The invention belongs to the novel technical field of medicaments, and relates to a novel dosage form of amoxicillin used for treating: 1, upper respiratory tract infections, such as tympanitis, nasosinusitis, pharyngitis and tonsillitis resulted from streptococcus hemolyticus, streptococcus pneumoniae, staphylococcus or haemophilus influenzae; 2, genitourinary tract infections resulted from escherichia coli,proteus mirabilis or enterococcus faecalis; 3, skin and soft tissue infection resulted from streptococcus hemolyticus, staphylococcus bacteria or escherichia coli; 4, lower respiratory tract infections, such as acute bronchitis and pneumonia, resulted from streptococcus hemolyticus, streptococcus pneumoniae, staphylococcus bacteria or haemophilus influenzae; 5, acute simple gonorrhea; and 6, typhoid, typhoid bacteria-carrier, leptospirosis and the like. The novel dosage form is characterized in that the stomach floating tablet is hydrated into gel on the surface to expand the volume thereof after contacting with the gastric juice at the body temperature because of a plurality of hydrophilic macromolecular materials contained. Meanwhile, the weight of the tablet is less than the buoyant force of the gastric juice to float the tablet on the gastric juice and prolong the retention time in the stomach.

The invention relates to a cefonicid sodium hydrate and a preparation method and application thereof. The cefonicid sodium hydrate has better storage stability and is applicable to preparation of the medicaments for treating or preventing such diseases caused by gram positive or negative sensitive bacteria as respiratory system infection, hepatobiliary system infection, five sense infection, urinary tract infection, abdominal infection, pelvic infection, sepsis, skin soft tissue infection, bone and joint infections, annexitis, intrauterine infection, parametritis, meningitis, gonorrhea and the like of human or animals.

The invention discloses a gonorrhea-antigen spittle rapid detection strip comprising a baseboard, to which a sample pad, a colloidal gold pad, a nitrocellulose membrane and a sample-drawing pad are sequentially adhered, wherein a first monoclonal antibody which is marked by colloidal gold and can be integrated with the specificity of the gonorrhea-antigen is attached to the colloidal gold pad; thenitrocellulose membrane is coated with a detection line formed by a second monoclonal antibody and a quality control line formed by an antiantibody which can be integrated with the specificity of thefirst monoclonal antibody; and the first monoclonal antibody is matched with the second monoclonal antibody. The gonorrhea-antigen spittle rapid detection strip provided by the invention adopts the colloidal gold marking technology to detect the gonorrhea-antigen contained in spittle so as to determine whether the person is infected with gonococcus, and has the advantages that operation is simple; reaction is quick; sensitivity is high; specificity is strong; and the gonorrhea-antigen spittle rapid detection strip can be applied to both on-site detection and self-detection, and is economicaland practical and the like.

A vagina-cleaning sanitary spray liquid comprises vagina-cleaning spray liquid and a liquid spray bottle, and the vagina-cleaning spray liquid consists of the following pharmaceutical components by weight percentage: 0.146-0.15 wt percent of hexamethylene guanidine hydrochloride, 0.195-0.2 wt percent of glycerol, 0.097-0.1 wt percent of peony root extract, 0.029-0.03 wt percent of rosemary oil and 1.95-2.0 wt percent of diphenhydramine. The components are mixed and prepared into water solution, the vagina-cleaning spray liquid is filled in the liquid spray bottle, and a liquid spray head is sealed for preparing the vagina-cleaning sanitary spray liquid. The vagina-cleaning sanitary spray liquid can not only effectively kill bacteria and viruses of skin and mucous membrane parts of whole body, but also have better effect for killing adult male and female genital skin and mucous membrane infected bacteria, fungi and viruses, thereby having the effect of killing bacteria, fungi, gonorrhea coccus, human papilloma virus and HIV and being capable of effectively preventing female bacterial vaginosis, fungal vaginitis, male and female gonorrhea, genital warts, AIDS and so on.

The invention relates to cefodizime sodium hydrate as well as a preparation method and application thereof. The cefodizime sodium hydrate has better storage stability, and is suitable for being applied to the preparation of drugs for treating or preventing human or animal respiratory system diseases, hepatobiliary system diseases, diseases related to the five sense organs and urinary tract infection, abdominal cavity infection, pelvic cavity infection, septicemia, skin and soft tissue infections, bone and joint infections, adnexitis, intra-uterine infection, parametric connective tissue inflammation, meningitis, gonorrhea and other diseases caused by Gram-positive or negative bacteria sensitive bacteria.

The invention belongs to the technical field of traditional Chinese medicine preparation, and discloses a drug used for treating gynecological diseases. The drug is prepared from, by weight, 15 to 25 parts of Caulis Polygoni Multiflori, 10 to 15 parts of dendrobium, 5 to 8 parts of radix astragali, 2 to 10 parts of honeysuckle flower, 5 to 10 parts of gentiana scabra, 10 to 20 parts of radix scrophulariae, 10 to 20 parts of radix salviae miltiorrhizae, 3 to 8 parts of cornus officinalis, 3 to 8 parts of emodiopteria appendiculata, 10 to 20 parts of common cnidium fruit, 6 to 15 parts of Sichuan pepper, and 2 to 5 parts of mineral powder. The drug possesses excellent curative effect on diseases such as cervicitis, colpitis, pelvic inflammation, endometritis, condyloma acuminatum, syphilis, herpes progenitalis, gonorrhea, AIDS, and uterine fibroid; curative rate is high; and recurrence rate is low.

The invention relates to establish a detection method mode for hog cholera virus genetic recombination adenovirus carrier vaccine rabbit body effect. An SPF rabbit which is stable in production performance and quality serves as a carrier, after rAd-Eo-E2 immunization is subjected to a rabbit body for 14 days, swine fever spleen vaccine serves as strain used for counteracting toxic substances, after the toxic substances is counteracted, rabbit body heat of reaction is monitored continuously for 3 days, the protective efficacy of the vaccine is evaluated according to situation of forming heat (>= 40.5 DEG C) occurring on the rabbit body, and the detection method mode for the for rAd-Eo-E2 rabbit body efficacy is established. In the method establishing process, by means of temperature monitoring, an index ratio of the spleen to weight of the rabbit, spleen tissue section observation, RT-PCR detection and swine fever spleen gonorrhea separation and identification of an immune group and a matched group, whether the protective efficacy of the rAd-Eo-E2 immunization displayed by the result is accordant or not is determined, and evaluation conducted by adopting a relatively simple, convenient and easy detection method of temperature monitoring is determined finally.

The invention discloses a method for preparing a preparation for treating gonorrhea. The method is implemented by the technical scheme which comprises the following steps of: uniformly spraying crystal sugar on polygonum aviculare, plantain seed, talc, bamboo leaves, rush, alismatis rhizoma and dianthus superbus and uniformly mixing and then spraying the talc on the mixture to steam for 10min; decocting the obtained product in river water in an earthen pot for 20min, wherein the ratio of the obtained product to river water is 1:1; and taking the mixture out and removing residues to obtain a finished preparation. The disease can be cured by the method within three days.

Disclosed are methods of treating an autoimmune or inflammatory disease using a composition comprising an isolated antibody or an antigen-binding fragment or variant thereof that is capable of binding to muramyl peptide, derivative, analog or salt thereof, wherein said muramyl peptide comprises muramic acid and an amino acid selected from the group consisting of alanine, isoglutamine, glutamic acid and a salt thereof. In one preferred embodiment, the composition can comprise of the isolated antibody or an antigen-binding fragment and one or more therapeutic agents such as Tumor Necrosis Factor (TNF) inhibitor. The autoimmune or inflammatory disease is selected from a group consisting of sepsis, septic shock, Crohn's disease, rheumatoid arthritis, asthma, allergy, atopic disorders, multiple sclerosis, pertussis, gonorrhea, inflammatory bowel disease, and antibiotic associated disorder.