Ceftizoxime sodium crystalline hydrate and preparation method and application thereof

A technology for ceftizoxime sodium and crystalline hydrate, which is applied in the field of ceftizoxime sodium crystalline hydrate and its preparation, can solve the problems such as the preparation method and application of ceftizoxime sodium crystalline hydrate that have not been reported in the literature, and achieves improved Workability, easy storage and transportation, good sliding effect
CN102180889AInactive Publication Date: 2011-09-14刘力
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
刘力
Publication Date
2011-09-14
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a ceftizoxime sodium crystalline hydrate and a preparation method and application thereof. The ceftizoxime sodium crystalline hydrate has better storage stability, and is suitable for being applied in the preparation of medicines for treating or preventing human or animal respiratory system, hepatobiliary system, five sense organs, urinary tract infection, celiac infection, pelvic infection, sepsis, skin soft tissue infection, bone and joint infection caused by gram positive or negative bacterial sensitive bacteria, meningitis and simple gonorrhea caused by streptococcus pneumoniae or haemophilus influenzae, and other diseases.
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Description

Technical field

[0001] The invention relates to the technical field of medicine, and specifically provides an antibacterial drug ceftizoxime sodium crystal hydrate and a preparation method and application thereof. Background technique

[0002] At present, the published literature only reports the third-generation cephalosporin-Ceftizoxime sodium (Ceftizoxime sodium) (C 13 H 12 N 5 NaO 5 S 2 , Molecular weight: 405.38, CAS number: 68401-82-1), so far, there is no published literature report on the ceftizoxime sodium crystalline hydrate of the present invention and its preparation method and application. Summary of the invention

[0003] The invention relates to the antibacterial infection drug ceftizoxime sodium crystalline hydrate and its preparation method and application. Its molecular formula is C 13 H 12 N 5 NaO 5 S 2 ·NH 2 O, n=1.5~1.85.

[0004] The ceftizoxime sodium containing crystal water obtained by the present invention is surprisingly wettability of ceftizoxime sodium c...

Claims

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