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70results about How to "Reducing and preventing symptom" patented technology

Method, apparatus, and surgical technique for autonomic neuromodulation for the treatment of disease

InactiveUS20060167498A1Reduce or prevent conditionReducing and preventing symptomSpinal electrodesSurgical needlesSplanchnic nervesDisease
The present invention teaches a method and apparatus for physiological modulation, including neural and gastrointestinal modulation, for the purposes of treating several disorders, including obesity, depression, epilepsy, and diabetes. This includes chronically implanted neural and neuromuscular modulators, used to modulate the afferent neurons of the sympathetic nervous system to induce satiety. Furthermore, this includes neuromuscular stimulation of the stomach to effect baseline and intermittent smooth muscle contraction to increase gastric intraluminal pressure, which induces satiety, and stimulate sympathetic afferent fibers, including those in the sympathetic trunk, splanchnic nerves, and greater curvature of the stomach, to augment the perception of satiety.
Owner:DILORENZO BIOMEDICAL

AAV vectors and methods

The invention relates to Adeno-associated virus vectors. In particular, it relates to Adeno-associated virus vectors with modified capsid proteins and materials and methods for their preparation and use.
Owner:NATIONWIDE CHILDRENS HOSPITAL +1

AAV2 vectors and methods

The invention relates to Adeno-associated virus vectors. In particular, it relates to Adeno-associated virus vectors with modified capsid proteins and materials and methods for their preparation and use.
Owner:NATIONWIDE CHILDRENS HOSPITAL

Method and apparatus for conformal electrodes for autonomic neuromodulation for the treatment of obesity and other conditions

InactiveUS20090118780A1Reduce or prevent conditionReducing and preventing symptomSpinal electrodesHead electrodesAfferent NeuronsAutonomic Denervation
The present invention teaches a method and apparatus for user control and operation of physiological modulation, including neural and gastrointestinal modulation, for the purposes of treating several disorders, including obesity, metabolic disease, and other conditions. This includes programming of neuromodulatory signal for the modulation of autonomic neural and neuromuscular modulators, used to modulate tissues, including the afferent neurons of the sympathetic nervous system to induce satiety and efferent neurons to modulate metabolism. The apparatus and methods include a conformal neuromodulator array which facilitates minimally invasive placement of neuromodulators in communication with target tissues.
Owner:DILORENZO DANIEL JOHN

Sustained release intraocular implants and methods for preventing retinal dysfunction

InactiveUS20050244506A1Few and no negative side effectFacilitate obtaining successful treatment resultsPowder deliveryBiocideMicrosphereRetinal dysfunction
Biocompatible intraocular microspheres and implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2 adrenergic receptor agonist into an eye for an extended period of time. The alpha-2 adrenergic receptor agonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. The implants may be placed in an eye to treat or to prevent the occurrence of one or more ocular conditions, to reduce one or more symptoms of an ocular condition, such as an ocular neurosensory disorder and the like, to enhance normal retinal function and / or to lower intraocular pressure.
Owner:ALLERGAN INC

Method and apparatus for programming of autonomic neuromodulation for the treatment of obesity

InactiveUS20090187230A1Reduce or prevent conditionReducing and preventing symptomSensorsDigestive electrodesAfferent NeuronsDisease
The present invention teaches methods and apparatus for user control and operation of physiological modulation, including neural and gastrointestinal modulation, for the purposes of treating several disorders, including obesity. This includes programming of neuromodulatory signal for the modulation of autonomic neural and neuromuscular modulators, used to modulate tissues, including the afferent neurons of the sympathetic nervous system to induce satiety and efferent neurons to modulate metabolism.
Owner:DILORENZO DANIEL J

Anti-aging composition, kit and method of use

InactiveUS20070237735A1Reducing and preventing age-related skin symptomReducing and preventing symptomBiocideCosmetic preparationsMADECASSIC ACIDAntioxidant
An anti-aging composition comprising: (i) at least one biomimetic oligopeptide having a sequence of 20 amino acids or less; (ii) at least one lipoaminoacid; (iii) at least one pentacyclic triterpenoid selected from the group consisting of asiaticoside, madecassic acid, asiatic acid and madecassoside; (iv) at least one antioxidant; and (v) tetrahydropiperine; a kit comprising such composition and a method of use.
Owner:LABES DERMO COSMETIK

AAV vectors and methods

The invention relates to Adeno-associated virus vectors. In particular, it relates to Adeno-associated virus vectors with modified capsid proteins and materials and methods for their preparation and use.
Owner:NATIONWIDE CHILDRENS HOSPITAL +1

Phytochemicals for treatment of mastalgia and endometriosis

New compositions are disclosed that comprise the phytochemical Diindolylmethane (DIM), as well as its precursor, Indole-3-carbinol (I3C), and cogener, 2-(Indol-3-ylmethyl)-3,3'diindolylmethane (LTR-1), acceptable carriers and / or excipients. These compositions are administered to prevent or reduce symptoms associated with mastalgia and endometriosis.
Owner:BIORESPONSE

Targeted delivery of botulinum toxin for the treatment and prevention of trigeminal autonomic cephalgias, migraine and vascular conditions

Botulinum toxin, among other presynaptic neurotoxins is used for the treatment and prevention of migraine and other headaches associated with vascular disorders. Presynaptic neurotoxins are delivered focally, targeting the nerve endings of the trigeminal nerve, the occipital nerve and the intranasal terminals of the parasympathetic fibers originating in the Sphenopalatine ganglion. The administration preferably targets the extracranial nerve endings of the trigeminal nerve in the temporal area, the extracranial occipital nerve endings in the occipital area, and the intranasal terminals of the trigeminal nerve and parasympathetic fibers originating in the Sphenopalatine ganglion. The delivery is carried out by way of injection or topically.
Owner:ALLERGAN INC

Oxylipins from stearidonic acid and gamma-linolenic acid and methods of making and using the same

Disclosed are novel oxylipins that are derived from γ-linolenic acid (GLA; 18:3n-6) and stearidonic acid (STA or SDA; 18:4n-3), and methods of making and using such oxylipins. Also disclosed is the use of such oxylipins in therapeutic and nutritional or cosmetic applications, and particularly as anti-inflammatory or anti-neurodegenerative compounds. Also disclosed are The invention novel ways of producing long chain polyunsaturated acid (LCPUFA)-rich oils and compositions that contain enhanced and effective amounts of SDA- and / or GLA-derived oxylipins.
Owner:DSM IP ASSETS BV

Targeted delivery of botulinum toxin for the treatment and prevention of trigeminal autonomic cephalgias, migraine and vascular conditions

Botulinum toxin, among other presynaptic neurotoxins is used for the treatment and prevention of migraine and other headaches associated with vascular disorders. Presynaptic neurotoxins are delivered focally, targeting the nerve endings of the trigeminal nerve, the occipital nerve and the intranasal terminals of the parasympathetic fibers originating in the Sphenopalatine ganglion. The administration preferably targets the extracranial nerve endings of the trigeminal nerve in the temporal area, the extracranial occipital nerve endings in the occipital area, and the intranasal terminals of the trigeminal nerve and parasympathetic fibers originating in the Sphenopalatine ganglion. The delivery is carried out by way of injection or topically.
Owner:ALLERGAN INC

Synergistic composition and method of retarding and ameliorating photo induced retinal damage and cataracts while ameliorating dry eye syndrome

A composition and method of retarding and ameliorating eye diseases and injuries is disclosed. The method comprises administering a synergistic mixture of certain carotenoids, including the carotenoid astaxanthin, with phospholipid and triglyceride bound EPA and DHA derived from Krill oil, in which said krill oil contains at least 30% total phospholipids, in a therapeutically effective amount to prevent, retard or treat eye and central nervous system diseases or injuries, such as age-related macular degeneration, cataract, dry eye syndrome due to glandular inflammation and other central nervous system degenerative diseases, photic injury, ischemic diseases, and inflammatory diseases.
Owner:US NUTRACEUTICALS LLC

Compositions and methods for inhibiting expression of pro-apoptotic genes

The invention relates to one or more inhibitors, in particular siRNA compounds, which down-regulate the expression of a pro-apoptotic gene selected from the group consisting of TP53; HTRA2; KEAP1; SHC1-SHC, ZNHIT1, LGALS3 and HI95. The invention also relates to a pharmaceutical composition comprising the compound, and a pharmaceutically acceptable carrier. The present invention further provides methods of treating a subject afflicted with a disease or a condition associated with those genes, comprising administering to the subject a pharmaceutical composition in a therapeutically effective dose so as to thereby treat the subject.
Owner:QUARK FARMACUITIKALS INC

Probiotic for administration to healthy young mammals during the weaning period for improving tolerance to newly introduced food stuffs

InactiveUS20140170126A1Enhancement of transient increase in humoral immune responsePrevent stateBiocideOrganic active ingredientsWeaningTolerability
The current invention is based upon administration of a probiotic, B. Lactis NCC2818 to healthy young mammals during the critical weaning period (in infants this period is usually from about 3 months to about 12, 18 or 24 months old), so as to accelerate the young mammal's adaptation to new food. The effectiveness of the invention is evidenced herein by morphological and immunological changes observed in a piglet animal model of weaning. Thus, administration of the probiotic according to the invention had a prophylactic effect, preventing the severe discomfort and pathological states associated with the introduction to novel foods during the weaning period.
Owner:NESTEC SA

Immunogenic compositions of staphylococcus aureus antigens

The present invention relates to immunogenic compositions, comprising polypeptides and polysaccharides from Staphylococcus aureus. The present invention also relates to immunogenic compositions, comprising Staphylococcus aureus capsule polysaccharides conjugated to a carrier protein. In addition, the invention relates to methods of inducing an immune response in subjects against Staphylococcus aureus using immunogenic compositions of the Staphylococcus aureus polypeptides and capsule polysaccharides.
Owner:WYETH LLC

Immunogenic compositions of Staphylococcus aureus antigens

The present invention relates to immunogenic compositions, comprising polypeptides and polysaccharides from Staphylococcus aureus. The present invention also relates to immunogenic compositions, comprising Staphylococcus aureus capsule polysaccharides conjugated to a carrier protein. In addition, the invention relates to methods of inducing an immune response in subjects against Staphylococcus aureus using immunogenic compositions of the Staphylococcus aureus polypeptides and capsule polysaccharides.
Owner:WYETH LLC

Optical detection of seizure, a pre-seizure state, and cerebral edema and optical fiber detection of the same

A method for using optical parameters to monitor for a physiological event and / or a state prior to the physiological event includes the steps of: illuminating neural tissue with diagnostic light of a predetermined frequency at a predetermined location; detecting magnitude of optical scattering by neural tissue of the diagnostic light as a function of time; and determining a signature signal of the optical scattering of the diagnostic light before the physiological event in the neural tissue becomes clinically manifested. An apparatus includes a source of diagnostic light of a predetermined frequency for illuminating neural tissue at a predetermined location, a detector of optical scattering and / or optical absorption by neural tissue of the diagnostic light as a function of time, and a signal processor for determining a signature signal of the optical scattering and / or optical absorption of the diagnostic light before the physiological event becomes clinically manifested.
Owner:RGT UNIV OF CALIFORNIA

Oxylipins from stearidonic acid and .gamma.-linolenic acid and methods of making and using the same

Disclosed are novel oxylipins that are derived from γ-linolenic acid (GLA; 18:3n-6) and stearidonic acid (STA or SDA; 18:4n-3), and methods of making and using such oxylipins. Also disclosed is the use of such oxylipins in therapeutic and nutritional or cosmetic applications, and particularly as anti-inflammatory or anti-neurodegenerative compounds. Also disclosed are The invention novel ways of producing long chain polyunsaturated acid (LCPUFA)-rich oils and compositions that contain enhanced and effective amounts of SDA- and / or GLA-derived oxylipins.
Owner:DSM IP ASSETS BV

Keratolytic composition with anti-allergic anti-inflammatory properties

A product with an enhanced medicinal and cosmetic composition with a specific utility of “Psoriasis, Eczema and like skin disorders application” is characterized by the fact that it comprises active agents and ingredients as vanilla extract, ammonium chloride, potassium chloride and quaternary ammonium compound having formulated at a specific pH value with other specially selected adjuvants and fillers.
Owner:MUNISEKHAR MEDASANI
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