17results about How to "Avoid development" patented technology

The present invention provides a compound represented by formula I, a racemate, an enantiomer, a diastereoisomer and a pharmaceutically acceptable salt thereof, and their use in preventing or treating a related disease caused by coronavirus and / or picornavirus infection.

The invention relates to the field of buildings, in particular to a reinforced concrete member manufacturing method and a post-cracking bending rigidity calculation method.The reinforced concrete member manufacturing method comprises the following steps that S1, a steel reinforcement framework is fixed to the set position of a concrete pouring mold, and a reinforced area of a concrete body is determined; s2, determining structural parameters of the reinforcing grooves and the reinforcing ribs; s3, the foam board is cut to enable the shape of the foam board to correspond to the shape of the reinforcing groove, and the foam board is fixed to the position, corresponding to the reinforcing area, in the concrete pouring mold; s4, concrete is poured into the concrete pouring mold, a concrete main body is formed after the concrete is cured and solidified, and after the concrete main body is demolded, the internal foam plate is emptied to form a reinforcing groove; and S5, reinforcing ribs are inserted into the reinforcing grooves, the reinforcing grooves are filled with UHPC, and machining of the concrete member is completed after maintenance. The bearing capacity and durability of the reinforcing system are improved, meanwhile, the glass fiber reinforced resin composite material in the retired wind power blade is applied to the reinforcing system, and the reinforcing cost is reduced.

Provided are a gene circuit, an RNA delivery system and the use thereof. Specifically, the gene circuit comprises at least an RNA fragment capable of inhibiting gene expression and / or a targeting tag having a targeting function. The gene circuit can be delivered to a host, enriched in organ tissues of the host and self-assembled to form a complex structure, and inhibits gene expression by means of the RNA fragment, thereby treating diseases. The delivery system comprises the gene circuit and a delivery carrier capable of delivering the gene circuit to organ tissues of a host for enrichment. The provided gene circuit has a targeting function and a treatment function, can quickly and accurately reach target organs and target tissues to exert a treatment effect, and is highly efficient with good results. The safety and reliability of the provided RNA delivery system are fully verified, and the RNA delivery system has good druggability, high universality, and great economic benefits and application prospects.

The present application discloses a method, device, equipment and storage medium for real-time preview editing of a web page, the method comprising the following steps: creating a blank template at a web page editing end, inserting the HTML source code of a published web page obtained from a remote server into the blank template; after monitoring that the blank template completes the insertion of the HTML source code, instantiating the blank template to preview the corresponding editable web page at the web page editing end; receiving editing data acting on the editable web page, storing the editing data in a global variable; in response to the data update of the global variable, refreshing the preview effect of the editable web page. The present application is suitable for providing an efficient editing solution for large-scale web page special development projects, and can better achieve code isolation and management.

A current collector includes a substrate layer and a conductive layer. The conductive layer is arranged on a surface of the substrate layer. The substrate layer includes a polymer layer and a metal material layer connected to each other. The metal material layer is connected to the conductive layer, and partially extends out of the conductive layer. A pole piece and a battery are further provided. The current collector has reduced metal content and improved weight energy density. Moreover, the current collector can be structurally damaged at the early stage of the thermal runaway, preventing the thermal runaway.

The utility model relates to the technical field of concrete anti-cracking, in particular to a floor mass concrete anti-cracking structure which comprises a concrete filling material main body, and the concrete filling material main body is filled with an anti-cracking structure. According to the floor mass concrete anti-cracking structure, a reasonable layered pouring method is adopted, that is, a construction method of layered pouring, layered vibration, one inclined plane, continuous flexible pouring and one-time top reaching is adopted for flexible pouring of concrete, the thickness of each layer is controlled within 400 mm, each layer is staggered by about 5 m, the gradient of the inclined plane is 1: 6, all pouring layers are staggered front and back, and flexible pouring is carried out in a layered mode. The upper layer is connected before the lower layer is initially set, the combination and quality of the upper layer and the lower layer of the concrete are ensured, the surface of the uppermost layer of concrete is rolled by an iron roller before the initial set, the surface compactness is enhanced, and the concrete is flattened by a wood trowel for not less than three times after water is collected, so that early plastic shrinkage cracks on the surface layer of the concrete are eliminated.

An embodiment of the present invention provides a method, device, electronic device and storage medium for displaying an interactive control. The method includes: in response to a selection operation on a notification message, obtaining a jump protocol corresponding to the notification message, the jump protocol at least including a control display identifier; displaying an application page corresponding to the jump protocol, and if the control display identifier represents displaying an interactive control, then displaying the interactive control while displaying the application page.

The present disclosure relates to the technical field of well logging methods and techniques, and particularly relates to a method and device for determining a lower limit of reservoir physical properties, equipment, a storage medium and a computer program. The method comprises: obtaining a core sample and a reservoir sample to be determined; performing data measurement on the core sample by using a preset phase permeability experiment to obtain sample basic data and dynamic porosity; making a scatter plot by using the sample basic data and the dynamic porosity; performing linear fitting on the scatter plot to obtain a porosity lower limit and a permeability lower limit of the core sample; performing reservoir classification on the reservoir sample to be determined by using the porosity lower limit and the permeability lower limit of the core sample to obtain an effective reservoir; performing data verification on the effective reservoir to obtain a verification result; and if the verification result is passed, performing conversion processing on the lower limit of reservoir physical properties of the core sample to obtain the lower limit of reservoir physical properties of the reservoir sample to be determined.

Disclosed in the present invention are a PARP inhibitor containing a piperazine structure, a preparation method therefor and pharmaceutical use thereof. Particularly, the present invention relates to novel compounds of general formulas (1), (2), (3), (4) and (5) and / or a pharmaceutically acceptable salt thereof, a composition comprising the compounds of general formulas (1), (2), (3), (4) and (5) and / or the pharmaceutically acceptable salt thereof, a preparation method therefor and use thereof as a PARP inhibitor in the preparation of anti-tumor drugs.

The embodiment of the present invention provides a data processing method, system, device and medium for large-scale heterogeneous unmanned aerial vehicles, which relates to the technical field of unmanned aerial vehicles, wherein the method includes: receiving frame data and video data of unmanned aerial vehicles; calling data mapping relationships according to the aircraft type of the unmanned aerial vehicle, converting each parameter in the frame data of the unmanned aerial vehicle into corresponding preset parameters, and obtaining converted frame data, each aircraft type has its own corresponding data mapping relationship, and the data mapping relationship is used to convert the frame data of all aircraft types into unified preset parameters; converting the video data into a preset video format for unified output, and obtaining converted video data; outputting the converted frame data and converted video data of unmanned aerial vehicles of all aircraft types through a unified communication protocol. This scheme makes the output data more unified and standardized, avoids the problems of different names for the same parameter and inconsistent parameter units, and makes the output data easier to use.

The present invention discloses a bacillus pilorei ( Paenibacillus peoriae R5‑3). The Paenibacillus pierrei can effectively produce lipopeptide dodecapeptide. The present invention also discloses a method for producing lipopeptide dodecapeptide using the Paenibacillus pierrei. The lipopeptide dodecapeptide produced by the present invention has high purity, stable structure under the gastrointestinal environment, and strong activity in inhibiting Gram-negative bacteria, and can be used for the development and utilization of leading veterinary drugs and feed additives for inhibiting diseases caused by various Gram-negative pathogens.

The invention relates to the technical field of bridge construction, in particular to multifunctional suspension irrigation construction equipment and method for a railway. Comprising a supporting system which can support the suspension irrigation equipment on an existing bridge surface. The main beam extends in the length direction of the bridge. The main beam is provided with an inverted-U-shaped portal frame, a cross beam of the inverted-U-shaped portal frame can abut against the main beam, and an opening of the cross beam faces the bottom of the main beam. A bottom platform is arranged at the bottom of the main beam and used for supporting the bottom face of the bridge. The formwork system comprises an outer formwork and an inner formwork, and the outer formwork is connected with the two ends of the opening of the inverted-U-shaped door frame. A plurality of vertical prestressed tendons are arranged between the outer formwork and the inner formwork and evenly distributed along the peripheral side of the inner formwork, one ends of the vertical prestressed tendons are connected with the main beam, and the other ends of the vertical prestressed tendons are connected with the bottom platform. Therefore, the to-be-erected bridge can be directly poured by adopting the pre-tensioning method to construct the vertical prestressed tendons on site, and the potential safety hazards that the grouting quality of a post-tensioning method is difficult to guarantee, the tension stress is uncontrollable and the like are avoided.

The invention provides a front-end element incidence relation determination method and device and electronic equipment. The method comprises the following steps: acquiring page data and script data of a front end; determining a plurality of interaction layers corresponding to the front end according to the page data and the script data; determining an intra-layer association relationship and a first inter-layer relationship respectively corresponding to the plurality of interaction layers; and determining a target association relationship corresponding to the front end according to the intra-layer association relationship and the first inter-layer relationship corresponding to the plurality of interaction layers. According to the method and the device, the technical problem of low development, operation and maintenance efficiency of the front end caused by inaccurate determination of the element association relationship when the element association relationship of the front end is determined in the related technology is solved.

The present invention discloses a high-strength and high-toughness fiber concrete based on geopolymer artificial aggregate and a preparation method thereof, wherein the preparation steps include: preparing geopolymer artificial aggregate; pre-wetting the geopolymer artificial aggregate to reach saturated surface dryness; mixing cement, silica fume and saturated surface dry geopolymer artificial aggregate, and stirring; adding water and a water reducer, and stirring to obtain a slurry; adding chopped fibers, and stirring; and putting into use after preliminary curing and soaking curing. The high-strength and high-toughness fiber concrete based on geopolymer artificial aggregate has a compressive strength of not less than 100MPa and an ultimate tensile strain of not less than 1%. The present invention uses industrial waste to synthesize geopolymer artificial aggregate, and based on this, regulates the microscopic mechanical properties of the fiber concrete material, thereby preparing a high-strength and high-toughness fiber concrete material, providing a new technical path for the high-value utilization of industrial waste and the performance optimization of cement-based materials.

Disclosed in the present invention are a fused cyclic compound as a Wee-1 inhibitor, a preparation method therefor and use thereof. Specifically, the present invention relates to a compound of general formula (1), a preparation method therefor, and use of the compound of general formula (1) or an isomer, a crystalline form, a pharmaceutically acceptable salt, a hydrate or a solvate thereof as a Wee-1 inhibitor in the preparation of an anti-tumor drug.

The invention relates to agriculture. The liquid complex fertilizer containing colloidal silver and a complex of macro- and microelements in the form of salt, as well as in the form of chelates - metal-ethylenediaminetetraacetic acid, while it additionally contains sodium tallow amphopolycarboxyglycinate, polyvinylpyrrolidone, water, pre-structured with shungite. All components are taken at a certain ratio. The invention makes it possible to increase the following: acaricidal activity against the common spider mite, the insecticidal activity against the common potato aphid, the antiviral activity against the tomato yellow leaf curl virus, and also the stability of the fertilizer as a colloidal system.

The present application provides a user identification card, a data transmission method, a device, a medium and a product, which belong to the field of Internet of Things technology. The user identification card (i.e., SIM card) receives the AT command sent by the MCU through the first interface, parses the AT command through the AT engine to obtain communication parameters and service data, sends instructions according to the communication parameters to control the cellular module to establish a data channel with the cloud service platform, and transmits the encrypted service data to the cloud service platform through the cellular module. The MCU no longer needs to process various security service-related instructions, but only needs to develop the original application layer business logic, avoiding the development of security services by the MCU, and the original software can be seamlessly connected, which reduces the connection threshold for security service upgrades. In addition, in the case of non-network connection, the uplink service data can be cached through the SIM card, and the SIM actively pushes data after the next network activation. The use of SIM security services does not require the cellular module to be turned on, which reduces power consumption.