3 results about "MADECASSIC ACID" patented technology

The present invention discloses synergistic herbal compositions comprising combination of a first ingredient selected from Centella asiatica extract containing at least one component selected from magnesium salt or complex of asiatic acid and magnesium salt or complex of madecassic acid or mixtures thereof along with asiaticoside and madecassoside; and a second ingredient selected from extract, fraction, phytochemical or mixtures thereof derived from Theobroma cacao; process for their preparation, methods of treatment and use of such nootropic compositions for improving cognitive functions or mental abilities and gaming performance.

The present invention belongs to the technical field of biomedicine. Disclosed is an asiatic-acid-derived ceramide, which has the structure of general formula (I) or an isomer of general formula I, wherein R1 is selected from one of the following structures in (II), and R2 is hydroxyl or a hydrogen atom. Further disclosed in the present invention are a method for synthesizing the asiatic-acid-derived ceramide and the use thereof. By means of the present invention, the solubility of ceramide is improved by means of introducing an asiatic acid or madecassic acid fragment with good fat solubility, thereby facilitating the use of ceramide in formulations. The compound of the present invention exhibits a significant inhibitory effect on inflammatory cytokine interleukin-6 (IL-6), and can also suppress the overexpression of TRPV1 receptors in sensitive skin and significantly reduce the expression of hyaluronidase, thereby achieving a good soothing effect.

The application provides a full-effect protection and prevention repair composition for acne skin and application thereof, and belongs to the technical field of cosmetics. The repair composition of the application is compounded with sulforaphane, lactoferrin, bromelain, madecassic acid lactone and guaiacum extract as active ingredients. The five substances can synergistically act together from multiple aspects, enhance the skin protection, improve the skin light damage, reduce the oxidative stress level, reduce the influence of stress hormone cortisol, and improve the emotional positivity, so as to achieve the effects of preventing acne, smoothing the skin and enhancing the barrier function.