158 results about "Anti ageing" patented technology

The invention belongs to the technical field of cosmetics, and discloses anti-aging recombinant collagen as well as a preparation method and application thereof. The amino acid sequence of the anti-aging recombinant collagen is as shown in SEQ ID NO.1, and the nucleotide sequence of the anti-aging recombinant collagen is as shown in SEQ ID NO.2. The recombinant collagen CaI1 is constructed and expressed by recombining the effective sequences of the I-type collagen, the III-type collagen and the XVII-type collagen, and the recombinant collagen CaI1 is free of cytotoxicity, free of hidden danger of endotoxin and good in safety. The skin care product added with the recombinant collagen CaI1 can promote skin collagen absorption, inhibit skin aging and improve skin elasticity, and has a good application prospect.

The invention belongs to the field of skin care products, and particularly relates to an anti-wrinkle and anti-aging composition as well as a preparation method and application thereof, and the anti-wrinkle and anti-aging composition comprises neurotransmitter inhibition peptide, signal peptide, madecassoside, inositol and glycosylglycerol. The neurotransmitter inhibition type peptide is at least three of acetyl hexapeptide-8, arginine / lysine polypeptide, dipeptide diaminobutyrylbenzylamide diacetate and acetyl octapeptide-3, and the signal type peptide is at least two of palmitoyl pentapeptide-4, decapeptide-4 and acetyl tetrapeptide-9. Compared with the prior art, all the components of the anti-wrinkle and anti-aging composition act on different anti-aging pathways and can be matched with one another from multiple aspects of oxidation resistance, inflammation resistance, moisturizing, cell viability enhancement, wrinkle reduction and the like, a more comprehensive and better anti-aging effect is provided, skin aging is comprehensively resisted, the skin is in a more young state, and the anti-wrinkle and anti-aging composition has the advantages that the anti-wrinkle and anti-aging effects are achieved. And the anti-wrinkle and anti-aging composition is small in irritation and good in stability.

The invention relates to an anti-aging composition for strengthening a skin supporting network and application thereof, and the anti-aging composition comprises the following components: a golden camellia flower extract, a saffron crocus extract, camellia seed oil, tranexamic acid and epigallocatechin gallate glucoside, the weight ratio of the golden camellia flower extract to the saffron crocus extract to the camellia seed oil to the tranexamic acid to the epigallocatechin gallate glucoside is (0.1 to 5) to (0.01 to 5) to (0.1 to 10) to (0.01 to 2) to (0.001 to 0.1). The composition provided by the invention can synergistically strengthen a skin support network and comprehensively improve skin elasticity and compactness by promoting growth of two core structural proteins and three macromolecular adhesives of skin, and is mild, non-irritant and suitable for people with sensitive skin.

The peptide complex of the present invention promotes the expression of the SIRT1 gene, referred to as a longevity gene, promotes the expression of the FGF21 gene, and increases the phosphorylation of AMPK. In addition, the peptide complex of the present invention exhibits an anti-inflammatory effect. Therefore, the peptide complex of the present invention inhibits aging, promotes the expression of the longevity gene SIRT1 gene, and can be used for treating or preventing diseases associated with SIRT1.

The invention discloses a polypeptide with anti-aging and anti-inflammatory activity and application thereof, and belongs to the field of biological medicine. In the prior art, anti-aging components are large in side effect, single in action target, unreasonable in polypeptide substance sequence design, insufficient in stability and difficult to give consideration to anti-aging and anti-inflammatory synergistic effects. The sequence provided by the invention comprises a polypeptide as shown in SEQ ID No.1 and a polypeptide with the homology not lower than 85%, and the polypeptide can be prepared into cosmetics or health care products. The polypeptide provided by the invention can promote collagen synthesis, inhibit inflammatory factors, improve skin aging and inflammation, and also can improve bone quality.

The invention discloses an anti-aging composition which comprises the following components or consists of the following components in parts by weight: 10-20 parts of pyrroloquinoline quinone or derivatives thereof; 2 to 30 parts by weight of ergothioneine; 0.2 to 10 parts by weight of spermidine; and 10-650 parts by weight of a pomegranate extract. The invention also discloses an application of the anti-aging composition. According to the anti-aging composition disclosed by the invention, the pyrroloquinoline quinone or the derivative thereof, the ergothioneine, the spermidine and the pomegranate extract contained in the anti-aging composition can generate a synergistic effect, so that the anti-aging composition has good anti-oxidation and anti-aging effects. The anti-aging composition can be applied to food, health care products and medicines, and has the effects of resisting skin oxidation and delaying aging.

The present invention relates to the technical field of dietary supplements, and more particularly to a composition formulation having an NMN anti-aging effect and a preparation method thereof. Technical Problem: the composition formulation having an NMN anti-aging effect and the preparation method thereof aim to solve the technical problem of not being able to enhance the body's resistance while also having an anti-aging effect, making the patient's body more energetic. Technical Solution: a composition formulation having an NMN anti-aging effect, including the following components: NMN 300 mg, PQQ 10 mg, coenzyme Q10 20 mg, ginsenoside 70 mg, aminobutyric acid 100 mg, other beneficial ingredients q. s.

The invention relates to a whitening and anti-aging composition which is characterized by comprising a solvent, a vitamin C derivative and an active agent, and the vitamin C derivative comprises 3-o-ethyl ascorbic acid, ascorbyl glucoside, magnesium ascorbyl phosphate, sodium ascorbyl phosphate and ascorbic acid polypeptide. By the adoption of the technical scheme, the whitening and anti-aging composition and the cosmetic containing the composition are high in stability, good in transdermal absorbability, lasting in effect, mild and capable of whitening skin and resisting aging in a synergistic mode.

The invention discloses cubilose peptide with an anti-aging function and application of the cubilose peptide. The amino acid sequence of the cubilose peptide is TFSLCEICETMVK. The cubilose peptide disclosed by the invention can resist aging, prevent diseases, beautify and protect skin, and improve the immunity of the organism, and has important significance in developing the efficacy of cubilose, improving the economic value of cubilose and expanding the application of the cubilose peptide.

The present application provides a kind of application of the steroid compound in preparation prevention or treatment skin pigmentation related condition or anti-aging related product, the steroid compound is as shown in formula I, and has treatment, lightening and / or alleviating effect on senile plaques, freckles, chloasma and the like caused by pigmentation on the skin of mammal.(I).

Compositions comprising specific tetrapeptides, for use in methods for treating, preventing, minimizing, diminishing or reversing various signs of aging of the skin are provided. The compositions are useful in improving the firmness or elasticity of skin, smoothing of fine-lines or wrinkles, reducing skin pores and hyperpigmentation, and increasing skin thickness, radiance and / or softness.

This invention relates to the field of cosmetics, and more particularly to active oligopeptides and their application in the preparation of anti-aging products. This invention provides an active oligopeptide with anti-aging activity, the amino acid sequence of which is shown in SEQ ID NO:1 and / or SEQ ID NO:4. This invention also provides an active oligopeptide (β1 and β1c) designed based on computational structural biology, targeting the β-Klotho FGF19 / / FGF21 and receptor-binding arm (RBA) region, and optimized for physicochemical properties, for use in skin anti-aging.

Compositions comprising specific tetrapeptides, for use in treating, preventing, minimizing, diminishing or reversing various signs of aging of the skin are provided. The compositions are useful in improving the firmness or elasticity of skin, smoothing of fine-lines or wrinkles, reducing skin pores and hyperpigmentation, and increasing skin thickness, radiance and / or softness.

The invention belongs to the technical field of cosmetics, and particularly relates to collagen peptide with an anti-aging effect as well as a preparation method and application of the collagen peptide. The amino acid sequence of the collagen peptide is as shown in SEQ ID NO.1, and the nucleotide sequence of the collagen peptide is as shown in SEQ ID NO.2. According to the invention, effective sequences of human III type and XVII type collagen are recombined to construct and express the collagen peptide Sa1, and the collagen peptide Sa1 has obvious antioxidant effect, no cytotoxicity and good safety. The skin care product added with the collagen peptide Sa1 can promote skin collagen absorption and effectively exert the anti-oxidation effect, so that the effects of improving skin elasticity and delaying skin aging are achieved.

The present invention relates to a Vaccinium macrocarpon extract comprising at least 80% peptides by weight of dry matter of the extract, in particular to a cosmetic active substance comprising same, to a cosmetic composition comprising said active substance and to anti-aging cosmetic uses.

The invention relates to an anti-aging composition. The compositions are achieved by topical compositions comprising specific amino acids and certain dicarboxylic acids or esters, which are capable of synergistically improving gene expression of type 1 collagen, which is an indication of skin anti-aging benefits.

The present invention provides a composition containing collagen and its application in anti-aging. More specifically, it provides an anti-aging polypeptide KS-C-6, which has good antioxidant and anti-apoptotic properties. Preparing a composition with the anti-aging polypeptide KS-C-6 and collagen can effectively increase the water content of the skin and treat the anti-aging effect of the skin.

The invention discloses an anti-aging composition as well as a preparation method and application thereof. The composition is prepared from the following components in parts by weight: 10 to 50 parts of ergothioneine; 5 to 25 parts of coenzyme Q10; 50 to 150 parts of 3-SL; 50 to 150 parts of collagen tripeptide; 100 to 500 parts of NAD (nicotinamide adenine dinucleotide); and 50 to 150 parts of glutathione. According to the anti-aging composition disclosed by the invention, various functional components such as the ergothioneine, the coenzyme Q10, the 3SL, the collagen tripeptide, the NAD < + > and the glutathione are reasonably proportioned, so that the anti-aging composition shows a remarkable synergistic anti-aging effect in in-vitro and in-vivo experiments. The anti-aging composition can enhance the cell antioxidant capacity, reduce the active oxygen level and promote the expression of collagen I and SIRT1, and compared with a single component or a non-optimized combination, the anti-aging effect is remarkably improved.

This invention provides the application of substances targeting the CYTB-187AA gene and / or protein in the preparation of drugs for delaying aging and / or prolonging lifespan. The research results of this invention indicate that by reducing the expression of CYTB-187AA protein and / or inhibiting its activity, the aging process can be effectively delayed, thereby achieving the goal of extending healthy lifespan or lifespan. The research results of this invention are of great significance for scientific research on aging mechanisms and the development of anti-aging intervention strategies.

The invention provides an anti-aging composition and a skin care product. The anti-aging composition is prepared from components in percentage by mass as follows: 5%-40% of hydroxypropyl tetrahydropyrantriol, 5%-40% of a skin feeling / rheology regulator and 2%-12% of a ternary compound, the ternary complex is prepared from the following raw materials: organic acid, amino acid and saccharides. The anti-aging composition provided by the embodiment of the invention can be used for improving the skin penetration of the hydroxypropyl tetrahydropyrantriol.

This invention belongs to the field of cosmetic technology, specifically relating to a collagen peptide with anti-aging effects, its preparation method, and its application. The amino acid sequence of the collagen peptide is shown in SEQ ID NO.1, and the nucleotide sequence is shown in SEQ ID NO.2. This invention constructs and expresses a collagen peptide Sa1 by recombining the effective sequences of human type III and XVII collagen. This collagen peptide Sa1 exhibits significant antioxidant effects, is non-cytotoxic, and has good safety. Skincare products containing collagen peptide Sa1 can promote the absorption of collagen in the skin, effectively exert antioxidant effects, thereby improving skin elasticity and delaying skin aging.

Cosmetic composition, e.g. an anti-ageing composition, comprising retinyl palmitate (pref. 0.25-0.5 wt.%), Silybum marianum seed oil (pref. 1-3 per cent by weight), betaine (pref. 2-4 weight per cent)

This invention discloses a layered anti-aging composition and its application. It comprises 4-10 parts of *Vigna angularis* fruit extract, 0.01-0.2 parts of soluble collagen, and 10-20 parts of *Fucus vesiculosus* extract, all parts by weight. The composition of this invention employs a layered anti-aging skincare strategy ("layered" generally refers to different skin areas, i.e., "cellular layer-dermis-epidermal layer"). This composition can promote the expression of LOR (lower retinal occlusion) and the relative expression level of TGM5 (epidermis), increase the content of type I procollagen C-terminal peptide and elastin (dermis), enhance mitochondrial activity, and increase ATP content (cellular layer). That is, it works progressively from the epidermis to the dermis to the cellular layer, having a relevant effect on each layer of skin, and possessing the functions of enhancing skin elasticity, firming, anti-aging, and repairing the skin barrier.

The present invention relates to a composition comprising an anti-aging peptide and, more specifically, to an anti-aging cosmetic, food, and pharmaceutical composition comprising the anti-aging peptide. The anti-aging peptide according to the present invention not only exhibits excellent skin permeability, but also demonstrates remarkable antioxidant activity, wrinkle reduction, skin elasticity enhancement, collagenase inhibition, or hyaluronidase inhibition effects, as confirmed experimentally. These findings indicate that the anti-aging peptide of the present invention possesses excellent anti-aging activity and thus can be variously used as a functional material in pharmaceutical, medicinal, cosmetic, and food fields.

An anti-aging catalyst composition includes a combination of cosmetically acceptable acids including at least three alpha hydroxy acids, at least one beta hydroxy acid, and one or more other cosmetically acceptable acids, the total amount of cosmetically acceptable acids in the anti-aging catalyst composition present in a range from about 5% to about 70%, each one of the cosmetically acceptable acids in the anti-aging catalyst composition present in a range from about 0.1% to about 69%, wherein the -aging catalyst composition has a pH ranging from about pH 1 to about pH 5.5.

The invention relates to an anti-aging composition, a firming and glowing essence containing the anti-aging composition and a preparation method of the firming and glowing essence. The anti-aging composition is prepared from the following components in parts by weight: 1.5 to 6 parts of glyceryl polyether-26, 1.5 to 5 parts of nicotinamide, 0.25 to 1.2 parts of xylitol, 0.13 to 0.3 part of sodium hyaluronate, 0.01 to 0.3 part of carnosine, 0.01 to 0.1 part of PCA sodium, 0.005 to 0.05 part of hydrolyzed collagen, 0.006 to 0.03 part of palmitoyl tripeptide-5, 0.0008 to 0.01 part of hexapeptide-9 and 0.001 to 0.01 part of dipeptide diaminobutyryl benzyl amide diacetate. Test results show that the tightening and glowing essence developed by adopting the composition has the effects of instantly supplementing moisture for skin, promoting collagen generation, improving wrinkles and helping the skin to recover a supporting structure so as to slow down aging, and has a good market prospect.

The present invention provides an application of enhanced and optimized mesenchymal stem cells and exosomes in anti-aging or delaying aging, belonging to the field of biopharmaceutical manufacturing technology. The pharmaceutical composition of the present invention exhibits significant synergistic effects in anti-aging interventions by combining the use of activity-enhanced mesenchymal stem cells and the exosomes they secrete. Experiments have confirmed that the composition can systematically improve oxidative stress damage associated with aging, significantly restore the activity of antioxidant enzymes in serum and brain tissue to near normal levels, and effectively reverse cognitive function degradation, as manifested by behavioral improvements such as shortened escape latency and improved spatial memory ability. It is suitable for the preparation of drugs or functional preparations that delay aging or anti-aging, and provides an innovative technical path for the development of efficient and safe anti-aging therapies.

The invention relates to an anti-aging composition, and belongs to the field of medicines and health-care product preparations. The composition is a microcapsule assembled by a water-soluble wall material, a first core material, a fat-soluble wall material and a second core material which are sequentially coated from outside to inside, and the first core material comprises beta-nicotinamide mononucleotide (NMN), nicotinamide ribose (NR), ergothioneine and trimethylglycine (TMG); the second core material comprises resveratrol, curcumin, pyrroloquinoline quinone (PQQ) and spermidine, and is dissolved in medium chain triglyceride (MCT oil) containing an antioxidant tocopherol. According to the dosage form, physical isolation and differentiated release of water-soluble and fat-soluble components are realized, and the problems of incompatibility among the components, poor stability, low bioavailability and the like are solved. Through the multi-target synergistic effect, the composition can effectively improve the NAD + level and enhance the mitochondrial function so as to improve the skin state and delay senescence.

The invention belongs to the technical field of anti-aging, and particularly discloses a composition and a preparation method and application thereof in preparation of a product with an anti-aging effect, and the composition comprises the following components in parts by mass: 10-50 parts of SOD yeast powder, 5-30 parts of epigallocatechin gallate, 10-60 parts of pleurotus citrinopileatus concentrated powder and 10-40 parts of emblic leafflower fruit extract. The composition provided by the invention plays a role in anti-aging core pathways such as oxidative stress removal, cell damage repair, metabolism regulation, immune enhancement and the like, and realizes anti-aging synergistic interaction in ways of pathway complementation, target point coordination and function amplification, so that the anti-aging effect is effectively improved.

Skin care compositions and, preferably, skin care compositions providing one or more improvements in skin appearance and, in some cases, also in skin health are disclosed herein. In accordance with an aspect of the invention, provided is a skin care composition comprising hyaluronic acid or a salt thereof; a silicone surfactant; one or more peptides; an extract; and a fatty component.