1214 results about "Bone quality" patented technology

Stent systems and methods for expanding and deploying stents in hard tissue such as bone, more particularly within a vertebral body. One exemplary method includes using a stent body that is coupled to a high speed rotational motor with the stent expandable and detachable from an introducer working end. In one embodiment, the stent is a deformable metal body with zig-zag type struts in an expanded configuration that carries diamond cutting particles bonded to the strut surfaces. The “spin” stent is rotated at high rpm's to remove cancellous bone from the deployment site together with irrigation and aspiration at the end of the probe that carries the stent. The stent may be expanded asymmetrically, such as with first and second balloons or by using an interior restraint, to apply vertical distraction forces to move apart the cortical endplates and support the vertebra in the distracted condition. The cancellous bone about the expanded stent as well as the interior of the stent can be filled with a bone cement, allograft or other bone graft material. In one method of use, the spin stent is designed and adapted for (i) treating a vertebral compression fracture (VCF) or for (ii) reinforcing an osteoporotic vertebral body.

Translational bone fixation assemblies, kits containing such assemblies, and methods of use are described herein. The described assemblies may be used in spinal fusion procedures in which a damaged or diseased disc (or part of a disc) is removed from between a pair of vertebrae and a spinal fusion spacer is placed between the vertebrae. The assemblies may be applied to an anterior portion of the affected vertebrae to span the affected disc space, and may be fixed to the vertebrae using bone screws. The assemblies may function to maintain the vertebrae aligned during the initial period following fixation in which fusion of the spacer to the adjacent vertebrae occurs. The assemblies may also function to share some of the axial spinal load applied to the fusion spacer to prevent extreme subsidence of the spacer into the vertebral body, such as where the patient has poor bone quality. The assemblies may also act to prevent the spacer from being expelled from the disc space during the initial post-operative period. Finally, these assemblies may be used in other parts of the body where the advantages of the assemblies are desired or applicable.

A method for estimating the skeletal status or bone quality of a vertebrate on the basis of two-dimensional image data comprising information relating to the trabecular structure of at least a part of a bone of the vertebrate, the image data being data obtained by exposing at least the part of the bone to electromagnetic radiation, such as X-rays, the method comprising subjecting the image data to a statistical analysis comprising a background correction procedure in which low frequency intensity variations not related to the trabecular structure of the bone are reduced relative to image data related to the trabecular structure of the part of the bone, a feature extraction procedure comprising (a) determining values reflecting the projected trabecular density in the image data, caused by the X-ray attenuating properties of cancellous bone in the part of the bone, for each of a number of locations or areas in the image data, (b) deriving one or more features from the variation of the determined PTD-values, preferably in the longitudinal direction of the bone, and an estimation procedure in which the skeletal status of the vertebrate is estimated on the basis of the one or more derived features and optionally other features related to the bone of the vertebrate and a predetermined relationship between the features and reference skeletal status parameters. Preferably, a profile describing the projected trabecullar density as a function of the distance along a line substantially at the center of the bone is determined, and information relating to skeletal status is derived from variations, fluctuations or other features of the profile.

The present invention provides a novel process for producing a calcium phosphate cement or filler which hardens in a temperature dependent fashion in association with an endothermic reaction. In the reaction a limited amount of water is mixed with dry calcium phosphate precursors to produce a hydrated precursor paste. Hardening of the paste occurs rapidly at body temperature and is accompanied by the conversion of one or more of the reactants to poorly crystalline apatitic calcium phosphate. The hardened cements, fillers, growth matrices, orthopedic and delivery devices of the invention are rapidly resorbable and stimulate hard tissue growth and healing. A composite material is provided including a strongly bioresorbable, poorly crystalline apatitic calcium phosphate composite and a supplementary material. The supplementary material is in intimate contact with the hydroxyapatite material in an amount effective to impart a selected characteristic to the composite. The supplemental material may be biocompatible, bioresorbable or non-resorbable. A method for treating a bone defect also is provided by identifying a bone site suitable for receiving an implant, and introducing a strongly resorbable, poorly crystalline apatitic calcium phosphate at the implant site, whereby bone is formed at the implant site. The implant site may be a variety of sites, such as a tooth socket, non-union bone, bone prosthesis, an osteoporotic bone, an intervertebral space, an alveolar ridge or a bone fracture.

Disclosed are methods of identifying subjects with osteoporosis or osteopenia, subjects at risk for developing osteoporosis, osteopenia, and bone fractures, methods of evaluating the effectiveness of osteoporosis treatments in subjects with osteoporosis or osteopenia, and methods of selecting therapies for treating osteoporosis or osteopenia, using biomarkers.

The invented healthy edible salt is prepared by mixing with sodium chloride, various amino acid, peptide substance, vitamin B family, polysaccharide, or chitin, antioxidant, nucleic acid seasoning, potassium chloride, calcium salt, magnesium salt, selenium salt, and potassium iodide. It can effectively prevent various diseases, also can prevent osteoporosis, cancer, diabetes, dysinsulinosis, lithiasis, coronary heart disease, senile dementia, bark farus etc. it also possesses the functions of antisenility, antifatigue, antidepression, improving immune power, promoting growth etc.

A method and systems for performing an osteotomy of a bone using a surgical navigation system without attaching a bone tracking device directly to any portion of the bone that will remain after the osteotomy includes affixing a tracking device to a portion of the bone that will be removed during the osteotomy, determining an anatomical profile of the bone; and performing cuts using positional guidance from the surgical navigation system.

The invention relates to ceramics and a production technology thereof, in particular to a household strengthen porcelain containing bone substances and the production technology thereof. The strengthen porcelain body comprises petalite, powdered alumina, bone powder, quartz, Longyan braying, Guizhou soil, Zimo saved soil and humic acid sodium; the glaze comprises spodumene, fritted glaze 317, bone powder, kaolin, zirconia, potassium feldspar and aedelforsite; the production technology of the strengthen porcelain comprises the steps of batching, water adding and ball milling, sifting out, iron removing, filter pressing, primary smelting, ageing, refining, molding, drying, glazing and kiln firing. The product of the invention has the advantages of high mechanical strength, good thermal stability, fine and glossy glaze, high whiteness, good transmittance and the like.

The invention relates to health food for enhancing human immunity and increasing bone mineral density and a preparation method thereof; the health food of the invention comprises the following components: hyaluronic acid, glucosamine, collagen, kudzu root extracts, chondroitin sulfate, vitamins, calcium, etc; because of the embedding processing of hyaluronic acid, the defect of property change of hyaluronic acid due to moisture absorption and influence of environmental factors is overcome; the health food prepared by the organic combination of the embedded hyaluronic acid with glucosamine, collagen, plant extracts, vitamins, mineral matter and the like has functions and effects which can supplement each other, has the effects of lubricating joints, increasing bone mineral density, and enhancing bone strength during long-term administration, and also has the functions of delaying aging, removing freckles and beautifying faces, and the like; the health food of the invention can be prepared into powder, granules, tablets, capsules, is convenient for carrying and taking, has stable and lasting efficacy, has no side effects, and is an ideal health food of patients with hypoimmunity and osteoporosis.

The instantly disclosed implant is designed to resurface or partially replace (two versions) the arthritic or osteonecrotic femoral head in an anatomic fashion with maximum fixation, durability and stability. It will serve a wide range of patient ages, arthritic/traumatic deformity, and bone pathologies while providing for high performance activity. The implant has absolute fixation utilizing existing, contoured femoral head bone with or without bone cement/porous texturing, an internal plate with modular head attachment, and advantageously benefit from the concurrent use of precision guided instrumentation. This implant optimizes maximal femoral head contact with or without porous contact surfaces but does not rely purely on the head for long term stability. This new concept prevents the common failure mechanisms of femoral neck fracture, loosening and malpositioning as well as makes patient bone quality less important for this high performance hip resurfacing implant.

A small-sized low cost modularized integration work system for diagnosing and treating osteoporosis integrates the diagnosis and the treatment; each functional module may work and be sold alone or integrally. A complete configuration has four functional modules: a dry-type supersonic wave bone density instrument, a low-frequency pulse magnetic field osteoporosis therapeutic instrument, an intelligent manpower sunbath lamp and a magnetic suspension vibration bone amount filliping instrument. Four functional modules share a common DSP or a microprocessor, a real time clock chip, LCD, a keyboard,a stabilized voltage supply and a cabinet. The supersonic wave bone density instrument measures an supersonic wave quantification parameter QUS of calcaneus; the low-frequency pulse magnetic field osteoporosis therapeutic instrument has a therapeutic chair/therapeutic bed structure, and generates a uniform strong pulse magnetic field to treat the osteoporosis by using four or five circular or square magnetic field coils; the intelligent manpower sunbath lamp accelerates human body to absorb calcium by using a medium wave ultraviolet health-care lamp tube; and the magnetic suspension vibrationfillips the increase of bone amount. The integrated work system has an inapproachable curative effect and a sexual valence ratio.

The present invention has an object to provide a transplant material allowing systemic bone substance improvement to be realized by cell transplant. The present invention teaches to use a transplant material comprising a cell selected from the group consisting of an embryonic stem cell, a mesenchymal stem cell, an osteoblast cell, a preosteoblast, a chondrocyte and a cell having a capability of bone formation through systemic or topical administration for the improvement in bone quality.

The epimedium extract which can be used for preparing medicine for curing osteoporosis is obtained by using Chinese medicinal materials epimedium through the processes of decocting in water, alcohol precipitation, macroporous resin adsorption, collecting eluent and concentrating eluent.

A non-toxic biologically active compound is provided having the following general formula (I):

wherein n is an integer from 1 to 14, preferably from 2 to 4, and R is an organic moiety, preferably a group different from but structurally substantially similar to 2-methyl naphthoquinone, or a group P—C(R₁)—P, where each P stands for a—PO(OH)₂ group and R₁ is a (poly)isoprenyl group, hydroxy, halogen (preferably chloro or bromo), or hydrogen, or a pharmaceutically acceptable derivative thereof. These compounds are useful for the treatment or prevention of certain disorders in a mammal, especially a human being, for example postmenopausal loss of bone in women, juvenile or senile osteoporosis in men and women, cardiovascular calcification and other ectopic calcifications.

The invention relates to a head maxillofacial bone implant and a method for quickly molding the same. The method is particularly a processing method for prosthesis for defects of the facial bones of human bodies, and the prosthesis is obtained by the aid of a processing technology for quickly polymerizing and molding powder. The method includes constructing maxillofacial post-traumatic models of patients according to image data of the bones of the patients; manufacturing three-dimensional models according to treatment repair requirements of clinical doctors by means of symmetric mirroring, curve design, database matching and the like. The image data of the bones of the patients are acquired by the aid of image diagnostic techniques such as CT (computed tomography) or MRI (magnetic resonance imaging). The three-dimensional models are matched with the traumatic positions of the patients. The head maxillofacial bone implant and the method have the advantages that the prosthesis models can be molded by the aid of the processing method for quickly molding the implant, and accordingly the prosthesis can be manufactured; the prosthesis which is processed in a personalized manner can be designed and processed for the patients with the maxillofacial defects and particularly patients with complicated defect structures, and the prosthesis with an anatomical repair effect and an effect of recovering functions of the maxillofacial organs of the patients can be manufactured.

The present invention relates to the preparation and use of novel bone templates that can be prepared using a comprehensive approach to observing microstructural features of bone, including trabecular thickness and trabecular density. These features are assessed in regions of interest in a bone (e.g., proximal femur, distal femur, wrist, spine, etc.) as observed using digital radiographic techniques or clinical imaging, such as Dual Energy X-ray Absorptiometry (DEXA) and computed tomography (CT) scanners. The microstructural features are presented in the form of data based on scanning results and are also assessed and/or organized in terms of age, gender, race, pathology, clinical history, and other patient population parameters. The template can be used to assess bone quality, predict the likelihood of bone fracture, and evaluate prosthesis design and placement, based on an image of a corresponding subject bone, e.g. the bone of a patient.

The disclosed preparation is prepared from dipsacus root, notoginseng, prepared rhizome of rehmannia, drynaria, native copper, frankincense, Chinese angelica root, Ligusticum wallichii, root of herbaceous peony, cortex acanthopanacis, myrrh, rhubarb horsetails, dragon's blood resin, radix paeoniae rubrathe, safflower, borax through pre-processing, weighing, mixing and disintegrating, grinding to obtain the synthesized medicinal powder.