75 results about "Senile osteoporosis" patented technology

A non-toxic biologically active compound is provided having the following general formula (I): wherein n is an integer from 1 to 14, preferably from 2 to 4, and R is an organic moiety, preferably a group different from but structurally substantially similar to 2-methyl naphthoquinone, or a group P—C(R1)—P, where each P stands for a—PO(OH)2 group and R1 is a (poly)isoprenyl group, hydroxy, halogen (preferably chloro or bromo), or hydrogen, or a pharmaceutically acceptable derivative thereof. These compounds are useful for the treatment or prevention of certain disorders in a mammal, especially a human being, for example postmenopausal loss of bone in women, juvenile or senile osteoporosis in men and women, cardiovascular calcification and other ectopic calcifications.

The invention provides a sugar-free high-calcium albumen powder for improving senile osteoporosis, comprising the following components by weight part of 100-160 parts of protein-like substance, 10-30 parts of collagen, 1-10 parts of thickening agent, 1-5 parts of phospholipid, 0.02-0.08 part of sweetening agent, 0.5-1.0 part of calcium salt (by the weight of calcium element), and 0.000002-0.000003 part of vitamin D. The sugar-free high-calcium albumen powder in the invention includes the collagen for achieving the effect of preventing osteoporosis or improving osteoporosis condition in daily food, and includes the vitamin D by compounding so as to be in favour of absorbing calcium salt. The product of the invention is fragrant and smooth, has good taste, aims to solve senile osteoporosis condition, and is extremely suitably used as daily food for the elders.

A medicine in the form of particle, tablet or capsule for preventing and treating rachitis and osteoporosis is prepared from VD, medicinal calcium, and 10 Chinese-medicinal materials including pilose asiabell root, astragalus root, ophiopogon root, white atractylodes rhizome, etc through decocting said Chinese-medicinal materials, concentrating, mixing with others, excipient and flavouring.

The invention discloses an application of an oligonucleotide compound of micro-RNA (ribonucleic acid) associated with senile osteoporosis. The oligonucleotide compound is used for filling in the gap of micro-RNA based oligonucleotide in application of preparing the compound for promoting osteoblast functions and inhibiting the senile osteoporosis. The technical scheme includes that the micro-RNA associated with the senile osteoporosis is obtained by screening, the oligonucleotide based on the micro-RNA associated with the senile osteoporosis is synthesized and transfected to into preosteoblast and senile osteoporosis mice bodies, results indicate that the osteoblast functions can be promoted, and the progress of the senile osteoporosis is inhibited. The prepared oligonucleotide based on the micro-RNA associated with the senile osteoporosis can inhibit the degree of the senile osteoporosis by promoting the osteoblast functions, and the gap of the micro-RNA based oligonucleotide in application of preparing the compound for promoting the osteoblast functions and inhibiting the senile osteoporosis is filled in.

The present invention is one kind of nutritious high-calcium flour with cucumber seed powder as high calcium additive. The nutritious high-calcium flour contains wheat flour 100 weight portions and cucumber seed powder in 2-35 weight portions. The nutritious high-calcium flour has excellent calcium replenishing effect, can raise sleep quality and motion state, and possesses special health effect for preventing and treating senile osteoporosis, spasm, rheumatism, etc.

The invention relates to a medicine combination for preventing and treating the osteoporosis, specifically a medicine produced by epimedium, bark of eucommia, fructus psoraleae, himalayan teasel root, astragalus root, native copper, chaff flower root and mongolian snakegourd root and the producing method thereof, which is suitable for preventing and treating constitutional osteoporosis including osteoporosis after menostasia and age-related osteoporosis and the fracture generated by constitutional osteoporosis.

Through a semisolid or solid fermentation technology, the invention relates to a traditional Chinese medicine fermented hair-blacking preparation which comprises the following components: fleece-flower root as a main component, Poria cocos, semen cuscutae, Psoralea corylifolia, mulberry, ligustrum lucidum, cortex moutan, achyranthes root, wheat bran and black tartary buckwheat. A preparation method comprises the following steps: taking the raw materials as a fermentation medium, adding water for covering the raw materials, immersing for 4-5 hours, adding a proper amount of water, placing in a pan (an extraction pot) for boiling for half hour, and cooling to room temperature; inoculating bacillus subtilis, aspergillus niger, Cordyceps militaris and Phylloporia ribis (or 2-3 bacterial strains of the above), fermenting for 72-84 hours (keeping at 28-30 DEG C), taking out, drying, crushing, packaging, irradiating and disinfecting to obtain the product. The traditional Chinese medicine fermented hair-blacking preparation has the advantages of no toxicity and no side effect, and has obvious antioxidation effect. The traditional Chinese medicine fermented hair-blacking preparation has effects for resisting aging and blackening hair, and can improve and treat senile osteoporosis, constipation, high blood fat and coronary heart disease.

The invention discloses an extraction method and the application of an urogenic stem cell exosome. The extraction method comprises the following specific steps: firstly, collecting urine, then carrying out first-time centrifugation, and adding PBS into a first residual liquid obtained after supernatant is removed; carrying out second-time centrifugation, resuspending the second-time residual liquid obtained after the supernatant is removed through a primary culture medium to obtain urogenic stem cell suspension solution; secondly, carrying out multiplication culture on the urogenic stem cellsand passing down to the second to the sixth generation for later use; thirdly, changing the culture medium obtained in the second step, then continuously culturing, collecting and culturing supernatant, centrifuging, filtering and carrying out centrifugal concentration; adding an exosome extraction reagent for extracting to obtain a resuspension solution of the urogenic stem cells. The urogenic stem cell exosome extracted by the invention is proved by animal experiments to have the advantages of good therapeutic effects on senile osteoporosis, postmenopausal osteoporosis and disuse osteoporosis.

The nano calcium is a kind of new material including two types. The first type, nano calcium powder, is particles prepared with calcium containing material includes ox bone, shark bone, oyster, etc. and through airflow crushing to 50-500 nm size, and may be mixed with cold or hot water and taken to replenish body's energy. The second type, nano slow-releasing calcium, is slow-releasing calcium tablet of 50-500 nm particles and produced via extraction or diacolation and subsequent nano coating process, and can maintain the calcium level inside body for certain period to raise body's bone quality. The present invention is significant in preventing and treating senile osteoporosis and teenage calcium deficiency.

The invention relates to a method for preparing a pharmaceutical preparation from salvianolic acid B for preventing and treating osteoporosis. Studies show that the pharmaceutical preparation prepared from the salvianolic acid B has extremely obvious functions for preventing and treating high-conversion type osteoporosis caused by the removal of ovarian rats, can be applied to preventing and treating senile osteoporosis clinically, and particularly has better functions for preventing and treating post-menopausal osteoporosis and the osteoporosis caused by medicaments of glucocorticoid.

The invention discloses mixed jam of wild kiwi fruits and wild ficus tikoua fruits and a preparation method of the mixed jam. The mixed jam comprises components as follows: 100 parts of wild kiwi fruits, 100 parts of wild ficus tikoua fruits, 50-75 parts of a sweetener, 0.3-0.7 parts of a thickening agent, 0.5-1.5 parts of citric acid and a proper amount of water and is prepared by steps of peeling, color protection, blanching, kernel removing, dicing, beating, mixing, blending, concentration, bottling, sealing, sterilization and cooling. The mixed jam of the wild kiwi fruits and wild ficus tikoua fruits has common natural edible and medicinal values of the wild kiwi fruits and wild ficus tikoua fruits and has effects of preventing senile osteoporosis, preventing and treating arteriosclerosis, improving the myocardial function, removing toxin, protecting the stomach, preventing gynecological diseases, inhibiting nitration reaction and the like. Low-sugar jam is developed through the compound use of the functional sweetener and sucrose, the jam with higher oxidation resistance and good flavor than products of the same type is developed through the compound use of the wild ficus tikoua fruits and wild kiwi fruits, and natural nutrients and flavor in raw materials are better preserved with an ultra-high pressure technology.

The invention discloses a traditional Chinese medicine composition for treating senile osteoporosis, and belongs to the technical field of traditional Chinese medicines. The effective ingredients of the traditional Chinese medicine are prepared from the following raw materials: wolfberries, Chinese yam, poria cocos, coix seed, herba epimedii, rhizoma drynariae, fructus cnidii, teasel root, fructus psoraleae, radix achyranthis bidentatae, eucommia ulmoides, dogwood, cornua cervi pantotrichum, cistanche, salvia miltiorrhiza, pseudo-ginseng, rheum officinale, corydalis tuber, radix polygoni multiflori, astragalus membranaceus, radix polygoni multiflori, chrysanthemum, Chinese date and liquorice. The traditional Chinese medicine disclosed by the invention is based on the traditional Chinese medicine mechanism of osteoporosis, focuses on tonifying kidney, benefiting liver, tonifying spleen, promoting circulation and removing stasis and improving the whole organism of body, and treats senile osteoporosis from a source. The traditional Chinese medicine disclosed by the invention is capable of improving a treatment effect on senile osteoporosis in case of being taken with a common calcium source product and vitamin D.

The present invention discloses one kind of (-)-epigallocatechin gallate (EGCG)-Ca complex solid dispersion and its preparation and application. The EGCG-Ca complex solid dispersion contains EGCG-Ca complex and PVP-k30 in the weight ratio of 1 to 4-25, optimally 1 to 7-12. The preparation process of the EGCG-Ca complex solid dispersion includes dissolving EGCG in deionized water, dropping saturated calcium salt solution while stirring and introducing protecting nitrogen until complete precipitation, collecting the precipitate, suspending and washing with deionized water, centrifuging to collect precipitate as the EGCG-Ca complex, mixing EGCG-Ca complex and PVP-k30 in required ratio, dissolving the mixture in water while introducing protecting nitrogen, high pressure homogenizing, filtering, spray drying the filtrate to obtain the EGCG-Ca complex solid dispersion, which is used in treating senile osteoporosis in high curative effect.

The invention discloses a traditional Chinese medicine preparation for treating senile osteoporosis. The senile osteoporosis belongs to bone impediment and bone wilting in traditional Chinese medical science. In a traditional Chinese medicine theory, the kidney stores essence, and the essence generates marrow, so that the osteoporosis is caused when muscles and bones cannot be nourished in a kidney essence deficiency state. According to the traditional Chinese medicine preparation, traditional Chinese medicines with the effects of tonifying the kidney and the spleen, nourishing the liver, the kidney, yin and yang, activating blood and benefiting vital energy are decocted with water to form decoction, wherein the traditional Chinese medicines are conic gymnadenia tubers, pyrola, alectoria asiatica du rietz, holly leaves, monkshood, dioscorea hemsleyi, textile screw pine seeds, roots of sandhill tylophora, variegate ladyslipper, smallflower microtis, purple gynura roots and mosla. A clinical test shows that the total efficiency reaches 95.2% and is remarkably superior to that of a reference group being 60.0%, so that the traditional Chinese medicine preparation is worthy of clinical popularization and application.

The invention provides a calcitriol liquid hard capsule, a method for preparing the same and application of the calcitriol liquid hard capsule. Every 1000 calcitriol liquid hard capsules comprise 0.25-0.5 mg of calcitriol, 140-170 g of oil-based matrixes and 25-40 mg of antioxidants. The method includes mixing the antioxidants and the oil-based matrixes with one another to obtain first mixtures; stirring and dissolving the first mixtures and then adding the calcitriol into the first mixtures to obtain second mixtures; continuing to stir and dissolve the second mixtures and then vacuumizing and degassing the second mixtures; filling hard capsule shells with the mixtures to obtain the calcitriol liquid hard capsule. The calcitriol liquid hard capsule, the method and the application have the advantages that the calcitriol liquid hard capsule can be effectively applied to treating post-menopause and senile osteoporosis, chronic renal failure and the like; the content uniformity of the calcitriol liquid hard capsule which is a medicine can be improved, the calcitriol liquid hard capsule is good in stability, long in quality guarantee period, high in bioavailability, low in cost and convenient to administer, and accordingly the calcitriol liquid hard capsule, the method and the application have obvious merits.

Belonging to the field of medical technology, the invention discloses a Chinese medicinal compound preparation for osteoporosis and a preparation method thereof. The Chinese medicinal compound preparation for osteoporosis is composed of, by weight part, drynaria rhizome, clematis root, Chinese angelica, Ligusticum wallichii, radix paeoniae rubra, rhizoma corydalis, rhizoma cibotii, eucommia and licorice. The invention also discloses a preparation method. By adopting the technologies and methods of modern cytobiology and molecular biology, from the aspects of molecule, cell, tissue, overall animal level and the like, the invention proves that waist impediment analgetic decoction can regulate BMP-2 / Smad pathway to inhibit senile osteoporosis. The successful completion of the invention can provide a new strategy for prevention and treatment of senile osteoporosis.

The invention provides a traditional Chinese medicine composition for treating senile osteoporosis. Medicines of the traditional Chinese medicine composition can meet the principle of compatibility of traditional Chinese medicines; and the traditional Chinese medicine composition firstly aims to fundamental reasons, takes prepared rhizome of adhesive rehmannia, leaf of Chinese wolfberry, bark of fragrant spicebush, root of redsepal eveningprimrose, tree peony bark, flower of delavay rhododendron, herb of david gentian, thinleaf milkwort root-bark, largehead atractylodes rhizome, hoodshaped alocasia rhizome, root of freyn cinquefoil and twig and leaf of eriocarpous glochidion as monarch and ministerial medicines to play roles in supplementing qi and invigorating the spleen, supplementing body essence and replenishing marrow, and warming the kidneys and supplementing body essence, and takes testes and penis of ursine seal, gecko house lizard, black pepper, fresh ginger, soybeans, carrots, pumpkin, mulberry fruit, spina date seeds, Chinese yam, yerbadetajo herb, common macrocarpium fruit and root of Japanese avens as adjuvant medicines to play roles in coordinating, enhancing the functions of the monarch medicines and ministerial medicines and restricting the toxic or side effects of other medicines. By virtue of the combination of the raw materials, the effects of the medicines can play synergistic action, so that the traditional Chinese medicine composition provided by the invention can be used for relieving both primary and secondary symptoms and is mild in medication so as to ensure that senile osteoporosis can be effectively treated; and the traditional Chinese medicine composition can achieve an ideal treatment effect, also is safe, is small in toxic or side effects and simple to prepare, can be used for directly reaching a focus, is short in cure time, and is not easy to cause relapse after curing.

The invention relates to a bone health care marrow filling capsule, disclosing a bone health care marrow filling capsule. In the bone health care marrow filling capsule, 12 types of medicines, such as bone fat, herba epimedii, Eucommia ulmoides, walnut, teasel root, rehmannia, barbary wolfberry fruit, drynaria rhizome, endothelium corneum gigeriae galli, oyster, medicated leaven and the root of bidentate achyranthes serve as bulk pharmaceutical chemicals and are smashed, decocted, condensed, dried, screened and the like to obtain the bone health care marrow filling capsule. The bone health care marrow filling capsule has the peculiar curative effect on enhancing sexual functions, eliminating toxins, lowering blood lipid, replenishing essence, replenishing marrow, compacting bone and strengthening tendon. The bone health care marrow filling capsule is clinically applied to rheumatoid arthritis, senile osteoporosis and the like, has exact curative effect, obvious effect and no toxic or side effect and is safe and effective Chinese medicine formula.

The invention discloses bisphosphonate compounds. The bisphosphonate compounds have a structure shown in a formula II, wherein R1 is H, OH or halogen; R2 is an alkyl group M adopting a linear structure or a structure with a branched chain, a ring or an aromatic ring, and the alkyl group M contains 1 20 carbon atoms; R3 is H, OH, CN or an alkyl group N containing 1 20 carbon atoms. The novel bisphosphonate compounds enable bone formation and bone destruction of osteocytes to be kept in relatively ideal dynamic equilibrium for a patient suffering from senile osteoporosis.

An eucommia wine as a health-care one for improving sexual function, delaying senility, beautifying face and preventing senile osteoporosis, hypertension and cancer is prepared from strong distillateliquor, eucommia leaf, etc. in compatibility.

The invention discloses lucid ganoderma wine for preventing middle-aged and senile osteoporosis. The lucid ganoderma wine has the original nutritional value of wine and certain health care efficacy for preventing and treating middle-aged and senile osteoporosis, has nutritional and health care efficacies, and can facilitate calcium absorption of bones of middle-aged and elderly people and maintain the normal physiological function of human bodies with long-term consumption. The lucid ganoderma wine comprises the following components: wine raw stock, lucid ganoderma, cortex eucommiae, radix salviae miltiorrhizae, radix achyranthis bidentatae, Chinese wolfberries, fructus jujubae and crystal sugar, the preparation technology is simple, the production cost is low, and the lucid ganoderma wine can be stored at a normal temperature.

Compounds of the formulaR1 and R2 are independently alkyl of 1 to 6 carbon atoms, allyl, or substituted allyl of 3 to 6 carbon atoms; R3 is hydrogen, alkyl of 1 to 6 carbon atoms, or cycloalkyl of 3 to 10 carbon atoms; and R4 is phenyl or naphthyl substituted with alkyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms or NR5R6; substituted or unsubstituted phenylalkyl wherein the alkyl group contains 1 to 6 carbon atoms; substituted or unsubstituted 5 to 10 membered heteroaryl having 1 to 3 heteroatoms selected from N, S and O; substituted or unsubstituted cycloalkyl of 3 to 10 carbon atoms; or substituted or unsubstituted cycloalkylalkyl of 4 to 10 carbon atoms; provided that phenyl or naphthyl is substituted with NR5R6 when R1 and R2 is alkyl, are useful in the treatment of various disorders associated bone loss by increased transcription and elevation of plasma calcitonin levels. Such disorders include, but are not limited to: Paget's Disease, post menopausal osteoporosis, senile osteoporosis, and glucocorticoid-induced osteoporosis.

The invention provides a Chinese medicinal preparation for treating osteoporosis, which is prepared from a Herba Epimedii extract with icariin content being higher than 10% and / or a Cnidium monnieri fruit extract with osthole content being higher than 10% and / or a Dipsacus asperoides extract with asperosaponin VI content being higher than 10% by mixing at an optional proportion. The Chinese medicinal preparation has hormone-like action; and has the effects of regulating in vivo calcium and phosphorus metabolism, tonifying liver and kidney, reuniting bones, regulating blood circulation, and improving symptoms of osteoporosis, such as pain in waist and back and weakness of feet and knees. The Chinese medicinal preparation can be used for treating senile osteoporosis with high effectiveness, good therapeutic effect and low toxic and adverse effects.

The invention discloses an intelligent ultraviolet treatment cabin for treating senile osteoporosis diseases, and relates to the technical field of treatment cabins. The intelligent ultraviolet treatment cabin for treating the senile osteoporosis diseases comprises a main cabin and an auxiliary cabin, wherein the main cabin and the auxiliary cabin are an integrated cabin, the main cabin and the auxiliary cabin are separated through a partition curtain, the auxiliary cabin is of a double-door structure, a seat and a clothes hook are arranged in the auxiliary cabin correspondingly, a touch display screen is arranged outside the integrated cabin, a first ultraviolet assembly, a second ultraviolet assembly, a ventilation fan, an emergency button, an interphone and a handrail are arranged in the main cabin, and a standing positioning indication mark is arranged between the first ultraviolet assembly and the second ultraviolet assembly. According to the intelligent ultraviolet treatment cabin, through arrangement of the main cabin, the auxiliary cabin, the first ultraviolet assembly, the second ultraviolet assembly, an intelligent control system and a data storage and data export system, the system is mainly used for physical treatment of the senile osteoporosis diseases and replaces medicine treatment, and the problem that the senile osteoporosis diseases are inconvenient to treat is solved.

The invention relates to crocodile bone meal and a preparation method thereof. The crocodile bone meal comprises crocodile bone powder, crystal sugar, yellow wine and crocodile colla corii asini, wherein the weight ratio of the crocodile bone powder to the crystal sugar, to the yellow wine and to the crocodile colla corii asini is (800-1200) to (20-40) to (4-6) to (1-3). The crocodile bone meal disclosed by the invention has the effects of strengthening the muscles and bones, replenishing essence, benefitting marrow and promoting blood circulation, can promote blood circulation, has good treatment effects on rheumatic osteodynia and rheumatoid arthritis, can have the effects of treating both manifestation and root causes of diseases, and can also prevent and treat senile osteoporosis, pediatric cartilage disease and the like; besides, the yellow wine is added, so that absorption can be facilitated, and nutrient substances of active calcium, phosphorus, bone glue and the like in the crocodile bone meal quickly enter human bodies; the crystal sugar is added, so that the problem that people suffer from excessive internal heat caused by eating the crocodile bone meal for a long term can be solved; and besides, the crocodile bone powder and the crocodile colla corii asini are organically combined, so that the effects and the efficacies of the crocodile bone powder and the effects and the efficacies of the crocodile colla corii asini can be well exerted.

The invention discloses a pharmaceutical composition for preventing senile osteoporosis and a preparation method thereof. The pharmaceutical composition is composed of daphne tangutica, diplazium donianum, euparotin, betulinic acid, and root of iris speculatrix according to a certain ratio. The pharmaceutical composition can be made into various dosage forms by a conventional preparation technology and has a prominent effect on preventing senile osteoporosis.

The invention discloses an umbilical cord mesenchymal stem cell exosome as well as an extraction method and application thereof. According to the extraction method disclosed by the invention, the umbilical cord mesenchymal stem cell exosome is extracted by using the umbilical cord mesenchymal stem cells pretreated by rapamycin, and the exosome is used for preparing the medicine for treating the bone defect related to the senile osteoporosis; the mechanism of the medicine for treating senile osteoporosis-related bone defect (SORBD) is that senile bone marrow mesenchymal stem cells are improved through the extracted umbilical cord mesenchymal stem cell exosome, and the osteogenic capacity and proliferation capacity of the bone marrow mesenchymal stem cells can be remarkably improved, so that bone defect repair is promoted.

The invention discloses bone-strengthening probiotic formula milk powder for preventing senile osteoporosis, and every 100 g of the formula milk powder comprises the following components: desalted whey powder, inulin, calcium carbonate, 3.8-6.2 g of fructo-oligosaccharide, xylooligosaccharide, vitamin A (retinyl acetate), vitamin D (cholecalciferol), vitamin E (dl-alpha-tocopheryl acetate), ferrous sulfate, sodium selenite and the balance of water. The milk powder is prepared from the following raw materials by weight: 5g of yak bone marrow collagen peptide powder, 0.4-0.6 g of phospholipid, L-carnitine, sodium hyaluronate, milk mineral salt, hydrolyzed yolk powder, bifidobacterium lactis HN019 and the balance of skim milk powder. On the basis of the prior art, in addition to reasonable matching of calcium, phosphorus and vitamins, probiotics, angiopoietin and cysteine-inhibiting protease protein are particularly added, the bone tissue density is further improved and strengthened, and therefore the occurrence rate of osteoporosis is more effectively reduced.

The invention discloses an extraction method and the application of an urogenic stem cell exosome. The extraction method comprises the following specific steps: firstly, collecting urine, then carrying out first-time centrifugation, and adding PBS into a first residual liquid obtained after supernatant is removed; carrying out second-time centrifugation, resuspending the second-time residual liquid obtained after the supernatant is removed through a primary culture medium to obtain urogenic stem cell suspension solution; secondly, carrying out multiplication culture on the urogenic stem cellsand passing down to the second to the sixth generation for later use; thirdly, changing the culture medium obtained in the second step, then continuously culturing, collecting and culturing supernatant, centrifuging, filtering and carrying out centrifugal concentration; adding an exosome extraction reagent for extracting to obtain a resuspension solution of the urogenic stem cells. The urogenic stem cell exosome extracted by the invention is proved by animal experiments to have the advantages of good therapeutic effects on senile osteoporosis, postmenopausal osteoporosis and disuse osteoporosis.

The invention discloses an intelligent anti-falling device for senile osteoporosis. The intelligent anti-falling device comprises a supporting frame, a connecting supporting frame is arranged above the supporting frame, the connecting supporting frame is fixedly connected with the supporting frame through a supporting rack, universal wheels are fixedly connected with the supporting frame through a plurality of bolts, a connecting box is arranged on one side of the upper end of the supporting frame, a seat assembly is arranged on the side, away from the upper end of the connecting box, of the supporting frame, an electric control box is arranged on the inner wall of one end of the connecting supporting frame, the top end of a connecting cylinder is of a convex ring structure and is slidably connected with the inner wall of a convex groove, buffering air bags corresponding to arms are arranged in arm bearing pads, a protection plate is arranged at one end of the connecting supporting frame, the protection plate is connected with the connecting supporting frame in a matched mode through a connecting rotating shaft, and the other end of the connecting supporting frame is connected with the protection plate through a lock catch. The intelligent anti-falling device for the senile osteoporosis has the advantages that a chair assembly can form a chair connecting structure, a patient can have a rest conveniently after exercise, and the chair assembly is convenient to use and rapid to operate.