The invention discloses high-calcium sesame paste and a preparation method thereof. The high-calcium sesame paste is prepared from the following materials in parts by weight: 100-110 parts of sesame, 20-22 parts of oat, 0.3-0.4 of calcium gluconate, 12-14 parts of osmanthus-fragrans beef yoghourt, 2-3 parts of pear, 3-4 parts of strawberry, 6-8 parts of jam, 20-22 parts of bean dregs, 3-4 parts of celery stalk, 4-6 parts of rose, 2-3 parts of rosemary, 1.5-3.5 parts of plantain herb, 3-4 parts of pepper leaves, 1-2 parts of pomegranate leaves, 4-5 parts of rhizoma anemarrhenae, 2-4 parts of phellinus igniarius, 4-5 parts of moss, 3-4 parts of kousa dogwood and 2-3.5 parts of corn stigma. The high-calcium sesame paste disclosed by the invention has the advantages that calcium is rich, the calcium supplementing effect is good, bone growth can be promoted, and the osteoporosis is prevented; due to addition of the yoghourt, the milk fragrance is strong, and the flavor is unique; and the high-calcium sesame paste also has the effects of clearing heat and promoting dieresis, improving eyesight and eliminating phlegm, clearing heat and fire, invigorating the stomach and activating blood.