3 results about "Postmenopausal women" patented technology

FIELD: therapy; cardiology; rheumatology.SUBSTANCE: used to predict osteopenic syndrome in postmenopausal women. Vascular stiffness is determined using the augmentation index, the presence of atherosclerotic plaques in the carotid arteries and the body mass index are assessed. The predicted probability of developing osteopenic syndrome (Y) is calculated using a special formula. For a probability value of Y ≥ 0.5 predicts osteopenic syndrome.EFFECT: increasing the accuracy and accessibility of predicting the risk of developing osteopenic syndrome in postmenopausal women at the preclinical stage by taking into account complex markers of vascular changes and metabolic risk factors.1 cl, 3 tbl, 3 ex

The present application relates to the technical field of biotechnology, and discloses a method for extracting menotropin from urine of postmenopausal women, which comprises the following steps: S1, filtering the urine of postmenopausal women, adjusting the pH value to 4-4.5, adding modified kaolin and mixing, adding perlite and mixing, standing, filtering, and drying to obtain kaolin adsorbate; S2, adding desorption liquid to the kaolin adsorbate, performing secondary desorption, combining the filtrates of the two times, adjusting the pH value to 8.2-8.7, standing, adding perlite and mixing, standing, filtering, ultrafiltering to obtain concentrated liquid, adjusting the pH value of the concentrated liquid to 5-5.5, adding acetone and mixing, standing, suction filtering, dehydrating with acetone, screening, and drying to obtain menotropin; the modified kaolin is obtained by compounding kaolin with chitosan first and then modifying the compound with amino silane. Through the above technical scheme, the problems of low extraction yield and purity of menotropin in the related art are solved.

This invention relates to the field of medical data processing technology, specifically to a diagnostic method for postmenopausal osteoporosis (PMOP) based on oral salivary bacteria. The method includes: collecting saliva samples from the subject in the morning on an empty stomach and labeling the subject's menopausal years; obtaining the relative abundance of Lactobacillus and Streptococcus, the concentrations of propionic acid and acetic acid, and the pH value; determining the corrected bone mineral density (BMD) correlation value using a diagnostic model; and outputting suggestions based on the BMD correlation value. This invention utilizes the principle that the decline in estrogen levels in postmenopausal women leads to an imbalance in the salivary flora, with an increase in acid-producing bacteria leading to increased acetic acid secretion and a decrease in alkali-producing bacteria leading to decreased propionic acid secretion. These two factors synergistically exacerbate osteogenic inhibition and increased bone resorption. Furthermore, since most saliva is partially absorbed after swallowing, the long-term accumulation of propionic acid and acetic acid can interfere with bone metabolism through the circulatory system, thus providing a preliminary diagnosis of PMOP. By collecting only saliva samples, without blood collection or radiation, the procedure is simple, painless, and provides physicians with preliminary diagnostic suggestions.