313 results about "Saliva sample" patented technology

An image processing system for predicting ovulation using a test channel for collecting saliva sample and a miniature camera for capturing the image of the saliva at dried state for analyzing the crystalline patterns for ovulation prediction. A rotary bristle element is attached to the drive head and a notch-like test channel traverses the width of the drive head. A conductivity sensor is mounted on a wall of the test channel for detecting filling and drying of the saliva sample. An algorithm in the microprocessor analyzes the image of the dried saliva and calculates the characteristic line length of line segments of connected saliva dots. A ferning index is also defined and calculated based on the percentage of area coverage of line segments which are exceeding the threshold line length. Trend curves are established based on the daily saliva analysis in a woman's menstrual cycle for predicting days from the ovulation.

In this testing device, a saliva sample and a buffer solution are delivered from separate chambers into a mixing chamber to mix with a second reagent. The resulting test mixture is allowed to incubate for a pre-determined period of time and then selectively delivered to a test strip

The present invention provides a method of evaluating the risk of possible caries and the device, system, and program of the same, which is useful for the subjects to keep their mouth conditions best by measuring the chemical properties of saliva samples collected from the mouths of subjects to allow for easy and sanitary evaluation of the risk of possible caries in a short time and to help the subjects accurately recognize their risk of possible caries and closely consult their dentist. In the present invention, saliva from the mouth of subject is collected, a given ratio of acid is added to the saliva, and the chemical property of the saliva is measured to evaluate the risk of possible caries base on the measured value.

A sample collection device having a sample tube, funnel, and cap having a capsule and a piercing insert, the capsule having a stabilization solution. After depositing the sample into the tube via the funnel, the cap is screwed onto the tube, piercing the capsule and releasing the stabilization fluid into the tube. The device can be used at home without clinicial supervision for collecting a saliva sample and transporting the sample to an analysis location for DNA analysis.

Test kit whereby the sponge portion of kit is used to swab saliva. The saliva is then extracted from sponge by either squeezing it out or through the use of a centrifuge. The sponge portion of the kit is attached to a collection container when used in the centrifuge. A filter can be placed between these two portions of the kit to filter out only substances of certain molecular weights and to clean saliva. When the saliva is collected by squeezing, the sponge is placed in soft walled vial that is squeezed to extract saliva. After extracted from the sponge, the collected saliva can be removed from kit by twisting off cap. This test kit can be used for, but not limited to, testing for HIV antibodies, hepatitis and drugs.

A pacifier is presented including a nipple configured to receive a plurality of breath and saliva samples from a user, a base portion configured for attachment to the nipple, and an output mechanism attached to the base portion and configured for displaying different nutritional information values. The output mechanism may include one or more removable strips. The plurality of breath and saliva samples received from the user via the nipple are analyzed for nutritional information, preferably, continuously and in real-time, and the nutritional information includes at least one of carbohydrates, fats, minerals, protein, fiber, vitamins, water, salt, sugar, sodium, antioxidants, and phytochemicals.

A saliva sample testing device has a base housing upon which is mounted an upper housing. The base housing has a drawer structure in which are formed reaction wells for receiving fluid specimens. The drawer may be slidable or pivotable out of this base housing to provide access to the reaction wells. In a modification the reaction wells are formed in the top surface of the base housing and the upper housing is tiltable upon or detached from the base housing to provide access to the reaction wells.

The invention provides a lectin test chip for a saliva sample, wherein a production cost is low, test targeting is strong, inherent advantages of a lectin chip are combined, and rapid, simple and efficient detection can be performed so as to obtain intermediate result information (saliva whole protein N-glycosylation and O-glycosylation carbohydrate chain structure information) adopted as type 2 diabetes mellitus evaluation. The lectin test chip adopts an epoxidation film base, and is characterized in that at least one of lectins such as PTL-I, LCA and SBA is immobilized on the epoxidation film base in a spotting immobilization manner. According to the present invention, the preparation method and the treatment method of the lectin test chip are optimized so as to establish the optimal reaction system for production of whole protein N-glycosylation and O-glycosylation information for saliva sample detection, and provide convenience for rapid and efficient detection of saliva glycoprotein carbohydrate chain structures of type 2 diabetes mellitus patients.

The relates to an agglutinin chip used for identifying cancer, in particular to an agglutinin chip for identifying breast cancer based on sialoprotein, a reagent kit and application of the reagent kit, and aims at providing an agglutinin chip for identifying breast cancer in a non-destructive mode through the change of carbohydrate chains in saliva, a reagent kit and application of the reagent kit. The agglutinin chip for identifying breast cancer based on sialoprotein comprises an agglutinin testing probe set. The agglutinin testing probe set at least comprises a combination of PHA-E+L, LTL, BS-I, MAL-I, LCA, BPL, PTL-II, NPA and GSL-I, or at least comprises a combination of LTL, BS-I, MAL-I, LCA, BPL, NPA and GSL-I. By means of the agglutinin chip, differentially-expressed glycoprotein carbohydrate chain structures in a patient saliva sample can be rapidly detected, whether a corresponding person suffers from a breast tumor or not is detected, and whether the breast tumor is breast cancer or not is determined; besides, saliva is adopted as an object to be detected and is easy and convenient to collect, and health risks existing when a serum sample is collected for detection in the prior art are avoided.

The invention provides a method for rapid nondestructive detection of a liver tumor marker and a test paper strip adopted by the method. A gold maker pad of the test paper strip adopted by the method comprises glass fibers adsorbed with colloidal gold-marked monoclonal antibodies GP73-1. A nitrocellulose film is orderly marked with a detection band T1 and a quality control line C, wherein monoclonal antibodies GP73-2 are fixed to the detection band T1 and rabbit anti-mouse polyclonal antibodies Ig are fixed to the quality control line C. The method for rapid nondestructive detection of a liver tumor marker comprises the following steps of taking a saliva sample, inserting an end of a sample pad of the test paper strip which is an immunochromotographic test paper strip into the saliva sample for 10 to 15min so that the saliva sample appears on a NC film, taking out the test paper strip, and observing coloring states of the detection band and the quality control line to obtain a detection result. The method utilizes a saliva sample as a detection object and compares the saliva sample with a serum sample and other body fluid samples. The method has the advantages of easy sample acquisition, nondestructive detection, accurate detection, safety, convenience, low cost and easy preservation.

The invention relates to a kit for detecting novel coronavirus N protein and an application of the kit. The kit comprises (1) one antibody capable of being bound to the novel coronavirus N protein, and (2) the other antibody marked by a marker and capable of being bound to the novel coronavirus N protein when the novel coronavirus N protein can be bound to (1) to limit the antibody. The using method of the kit comprises the step of determining whether a patient suffers from the novel coronavirus pneumonia or not by detecting the level of the novel coronavirus N protein in an individual sample.The kit for detecting the novel coronavirus N protein provided by the invention can be used for detecting the coronavirus N protein in nasopharynx swabs, oropharynx swabs, alveolar lavage fluids, serum, plasma, whole blood, sputum, oral swabs or saliva samples so as to be used for diagnosing novel coronavirus pneumonia.

A method of providing a risk evaluation and diagnosis of human oral cancer, by examining at the presence in human saliva sample of a combination of particulate nucleic acids from bacteria, virus, as well as human, and/or the presence of particulate biochemical volatile organic compounds, which are indicative of an increased risk of oral cancer.

The invention relates to an immunochromatographic kit for rapidly detecting novel coronavirus N protein as well as a preparation method and application of the immunochromatographic kit. The immunochromatographic kit comprises a test strip, the test strip comprises a detection line and a quality control line, the detection line is coated with an anti-novel coronavirus N protein antibody, and the quality control line is coated with a goat anti-rabbit polyclonal antibody. The immunochromatographic kit for rapidly detecting the novel coronavirus N protein provided by the invention can be used fordetecting the novel coronavirus N protein in a nasopharynx swab, an oropharynx swab, an alveolar lavage fluid, an oral swab or a saliva sample so as to be used for diagnosing novel coronavirus pneumonia.

The invention relates to a method for separating and assaying organic acid and fatty acid substances in saliva, belongs to the technical field of analytical chemistry and particularly relates to the method dedicated to separating and assaying the organic acid and fatty acid substances in the saliva. The method comprises the steps of collecting a saliva sample by adopting absorbent cotton, then, putting the absorbent cotton into a needle cylinder of a syringe, carrying out pushing squeezing by using a push rod of the syringe so as to obtain the saliva sample, carrying out high-speed centrifugation, then, extracting supernatant, then, carrying out salting-out extraction, a methyl esterification reaction and solvent extraction separation sequentially, then, concentrating an extract until the extract is approximately dry, then, carrying out redissolving, carrying out filtrating by a microporous filtrating membrane, assaying the organic acid and fatty acid substances in the saliva by adopting a gas chromatography-mass spectrometry method by using filtrate, making a standard curve, and carrying out quantification by an external standard method. The method provided by the invention can be effectively used for assaying the organic acid and fatty acid substances in the saliva, is feasible, accurate and reliable, is low in detection limit and good in accuracy and has popularization and application values.

The present invention is in the medical and consumer arenas. The invention presents the use of a salivary amylase assay to diagnose, quantify, and monitor the hydration status, the onset and progress of shock in an animal that produces salivary amylase, such as a human. The assay tests the saliva sample from the animal. Test kits and assays for such use are also presented.

Methods for detecting anti-transglutaminase antibodies in a saliva sample containing the antibodies are disclosed. Saliva samples are pre-treated. The antibodies are subsequently detected in the pre-treated saliva by an immune reaction with a transglutaminase under conditions suitable for forming immuno-complexes with the antibodies. The method is useful for diagnosing and/or therapeutically controlling celiac disease.

An ovulation-prediction device with an image processing system containing a transmissive test platen for placing saliva samples and a miniature camera for capturing the image of saliva sample at dried state for analyzing the increase of salt content for predicting ovulation. An image processing method with an algorithm described for removing noise in a saliva sample for calculating the density of dark pixels which represents salt content in the sample. A Density Index is defined. Trend curve of Density Index vs. day is established based on the daily saliva analysis in a woman's menstrual cycle for predicting days from the ovulation. Also illustrated are applications of the image processing system in an electrical toothbrush, a dental massager and a portable compact device using a disposable tape cassette for testing saliva samples.

The invention relates to a composition for preserving DNA in saliva, comprising denaturant, buffer, chelating agent, sodium chloride and polyethylene glycol. The composition of the present invention can effectively preserve DNA in saliva for a long time at room temperature, effectively reduce the degradation of DNA in isolated saliva, ensure the integrity of DNA, facilitate subsequent nucleic acid detection research, and is simple to use and easy to operate. It is convenient and greatly saves the processing time of saliva samples.