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115 results about "Saliva collection" patented technology
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You must collect saliva four times in one day. After each collection, place the sample in the freezer immediately. PINK or PURPLE TUBE should be collected 30 minutes after awakening (even if staying in bed), before breakfast and brushing teeth. GREEN TUBE should be collected before lunch.
Immunoassay that provides for both collection of saliva and assay of saliva for one or more analytes with visual readout
InactiveUS6248598B1Eliminate riskBioreactor/fermenter combinationsBiological substance pretreatmentsAnalyteSaliva sample
A device that provides for both the collection of saliva and detection of at least one analyte therein, e.g., a drug, is provided. This device provides for rapid analysis of saliva samples, while also providing a convenient assay method that does not require the addition of extraneous reagents, or other materials. Thereby, this device can be used by non-laboratory personnel without risk of user introduced errors.
Owner:BOGEMA STUART C
In-vitro diagnostic medical devices for determining saliva volume
InactiveUS20060073538A1Good reproducibilityImprove reliabilityMicrobiological testing/measurementVaccination/ovulation diagnosticsDentistryMedical device
The invention relates to a method of collecting saliva from the oral cavity for detecting a test substance, comprising the steps of (a) cleaning the oral cavity, (b) stimulating saliva secretion with a saliva-collecting solution, (c) removing the saliva-saliva collecting solution mixture from the oral cavity and collecting it in a container (1), (d) transferring the saliva-saliva collecting solution mixture into a sealable collection vessel.
Owner:GREINER BIO ONE GMBH
Saliva collection device
ActiveUS20120046574A1Preventing accidental leakingFunction increaseVaccination/ovulation diagnosticsDiagnostic recording/measuringSaliva collectionRespirator
A device for collecting oral fluid includes a mouthpiece with a fluid inlet connected to a collection chamber. The collection chamber includes a collecting vessel, a venting outlet, and an access port. The venting outlet may be covered by a liquid-impervious or resistant membrane, such as a hydrophobic membrane, and the access port is suitable for removing some or all of the collected fluid. This arrangement allows a saliva donor to continuously spit saliva and blow air into the closed collection chamber, without pressure build-up in the collection chamber, and without the need for the donor to release from the device until the desired oral fluid volume is collected. A valve, including a check valve may be in the saliva flow stream and baffles and structure creating a tortuous path may be utilized to keep saliva away from the membrane.
Owner:REFLEX MEDICAL CORP
Home test for glycated albumin in saliva
InactiveUS20080227210A1Withdrawing sample devicesVaccination/ovulation diagnosticsSaliva sampleSaliva collection
A home test for measuring glycated albumin levels in saliva. The saliva sample is collected at home using a standardized saliva collection kit and mailed to a testing laboratory that performs the test and reports the result directly back to the customer via the internet. The home test can be used to monitor glucose control in diabetics and in healthy individuals. It may also be used as a diagnostic aid in identifying individuals with diabetes, or who are at risk of developing diabetes.
Owner:SMITH HENRY
System for saliva collection
InactiveUS20170007215A1Eliminates unnecessary long processing wait timeLarge scaleSurgeryVaccination/ovulation diagnosticsElectricitySaliva collection
Disclosed herein are portable handheld devices for saliva collection for daily monitoring of salivary biomarkers of physiological conditions, the device comprising: a handheld handle comprising a saliva collector, the saliva collector comprising: a suction tip; a bi-directional pump electrically configurable for pumping towards two opposite directions; a saliva reservoir; a valve; a water reservoir, the water reservoir comprising an external filling lid; a reversible fluidic connection configurable in a connected and disconnected position; and a base accommodating the handheld handle, the base configurable to fluidly communicate with the handheld handle through at least the reversible fluidic connection, wherein the valve is electrically configured to allow fluid communication directly between at least two selected from: the saliva reservoir, the water reservoir, and the reversible fluidic connection, and wherein the bi-directional pump is electrically configurable to allow fluid communication directly between the suction tip and the saliva reservoir.
Owner:SLIVE INC
Improvements in and relating to sample collection
ActiveUS20170196542A1Reduce the cross-sectional areaSurgical furniturePreparing sample for investigationSaliva collectionAssay Unit
Sample collection apparatus and methods of sample collection are provided, for example saliva collection apparatus and methods of saliva collection. Said apparatus conveniently comprises a filter assembly and an interface for delivering material from the apparatus to an assay unit.
Owner:NEPESMO LTD
Efficient saliva collection device
PendingCN107233111ASimple structureEasy to useSurgeryVaccination/ovulation diagnosticsSaliva collectionAcquisition time
The invention discloses an efficient saliva collection device. The device comprises a collection funnel, a funnel cover, a saliva secretory substance stimulation volatilization chamber, collection tubes and a collection tube cover, wherein the collection funnel is connected with the funnel cover through a connection sheet, the funnel cover is seamlessly fastened on the collection funnel, and the saliva secretory substance stimulation volatilization chamber is formed in the fastening surface of the funnel cover; saliva secretory substance stimulation patterns are printed on the inner sides of the funnel cover, openings are formed in the upper ends of the collection tubes, and the bottom ends of the collection tubes are sealed; cone collection tube bottoms are arranged at the bottom ends of the collection tubes, tube edges extend to the bottom ends of the collection tubes, outer spiral screw threads are arranged on the outer sides of the openings of the upper ends of the collection tubes, and the tube edges are connected to the collection tube cover in a pluggable mode. The efficient saliva collection device is simple in structure and convenient to use, tedious steps of a split type are avoided, smell and vision neural reflex modes are used for simulating saliva to secrete quickly, and the sample collection time is shortened.
Owner:何向锋
Method for separating and determining multiple phenolic substances in saliva
ActiveCN106770760AEfficient separationEfficient determinationComponent separationMicropore FilterSaliva sample
The invention relates to a method for separating and determining multiple phenolic substances in saliva, and belongs to the technical field of analytical chemistry. The method comprises the steps of collecting a saliva sample by adopting a saliva collection tube, carrying out high-speed centrifugation after collection and then taking a supernatant; carrying out acidification, adding an internal standard and carrying out vortex oscillation until mixing evenly in sequence; and filtering with a micropore filter membrane, separating and determining multiple phenolic substances in saliva from filtrate by adopting an ultra-high performance liquid chromatography-multiwavelength fluorescence method, fabricating a standard curve and quantifying through an internal standard method. The method can be effectively used for separating and determining the multiple phenolic substances in the saliva, and the method is good in separation effect, low in detection limit, good in precision, accurate and reliable, and has popularization and application values.
Owner:CHINA TOBACCO YUNNAN IND
Apparatus and methods for reducing foaming during saliva collection
ActiveUS20140014112A1Reduced eliminated formationEasy to collectRespiratorsBreathing filtersSaliva collectionMedicine
A saliva collector comprises a reservoir, a bubble barrier, and a membrane, where the bubble barrier and membrane are arranged in tandem on a flow path from an inlet to an outlet on the reservoir. Air aspirated from a patient's oral cavity enters the reservoir through the inlet, passes through the bubble barrier to remove foam and bubbles, passes through the membrane to remove entrained liquid saliva, and passes out through the outlet.
Owner:SOMNICS INC
Saliva collection device
ActiveUS9113850B2Preventing accidental leakingReduction tendencySurgeryVaccination/ovulation diagnosticsSaliva collectionRespirator
Owner:REFLEX MEDICAL CORP
Saliva collection, processing, stabilization, and storage method
ActiveUS20140329705A1Microbiological testing/measurementPreparing sample for investigationSaliva sampleCell free
Provided herein is an all-in-one saliva collection apparatus that collects saliva to allow for the filtration of saliva in order to separate saliva components, such as extracellular proteins and nucleic acids that are not present in intact cells, from the intact cells and debris remaining in the extracted sample. The filtered saliva samples can be aliquoted into two fractions for protein and / or nucleic acid analysis. The present invention further describes long term storage at ambient temperatures of filtered salivary nucleic acids, and long term storage at ambient temperatures of filtered salivary proteins added to an ethanol solution. The filtered cell-free saliva samples have diagnostic usefulness.
Owner:RGT UNIV OF CALIFORNIA
Saliva collection device
ActiveCN105258976ASimple and fast operationImprove performanceWithdrawing sample devicesSaliva collectionSaliva sample
The invention relates to a saliva collection device which comprises a liquid storage pipe and a cover body, wherein the liquid storage pipe and the cover body are detachably connected and then form a liquid storage space internally; an isolation membrane is arranged inside the liquid storage space; the liquid storage space is segmented into two parts which are independent of each other by virtue of the isolation membrane; a piercing device is fixedly arranged in the cover body and is used for piercing the isolation membrane after the liquid storage pipe and the cover body are detachably connected with each other; and the liquid storage pipe is made of a transparent material or an opaque material. According to the saliva collection device provided by the invention, the liquid storage space is segmented into two parts which are independent of each other by virtue of the isolation membrane, and the isolation membrane is pierced during covering by utilizing the piercing device on the cover body, so that the operations of sealing ad mixing are simultaneously finished, and the problem of cross contamination among saliva samples is avoided.
Owner:上海思路迪医学检验所有限公司
Quantitative detection ovulation device and detection method
PendingCN107714096AImprove accuracyEasy to test yourselfSurgeryVaccination/ovulation diagnosticsStatistical analysisComputer module
The invention discloses a quantitative detection ovulation device, including a saliva collection module, an image acquisition module, a data transmission module, and a power module. The saliva collection module is used to collect saliva. The image acquisition module is used to acquire image data of saliva crystal, and comprises a micro microscopy device. The data transmission module is used to transmit data acquired by the image acquisition module to an APP module of an external device, to perform data processing and statistic analysis. The power module is used to supply power for the image acquisition module and the data transmission module. The device is convenient in operation, high in efficiency, and high in measuring precision, and can accurately calculate ovulation time in a dozen ofhours.
Owner:量准(上海)医疗科技有限公司
Fish shaped saliva collector
The invention belongs to a saliva collector, which improves the quality of care. The overall appearance of the saliva collector is fish-shaped, and consists of a saliva drainage groove, a liquid storage bottle, a fixed rope hole and the like. The rear part of the saliva drainage tank is higher than the front part, and the bottom is smooth, which is easy for saliva drainage; To increase air permeability, the interface between the liquid storage bottle and the saliva drainage tank is screwed and connected; there are rope holes on the surrounding wings, which are more secure after the rope is fixed, so that the saliva drainage tank will not slip or fall. The fish-shaped saliva collector is made of silica gel as a whole, which is non-toxic and harmless to the human body, and has good flexibility and comfort, which is easy for patients to accept.
Owner:陆生杰
Non-invasive saliva detection method for 1, 5-anhydroglucitol and application of non-invasive saliva detection method
ActiveCN110988165AEasy to collect and operateHigh acceptanceComponent separationSaliva sampleLiquid chromatography mass spectroscopy
On one hand, the invention provides a preparation method for 1, 3-butanediol. A saliva sample of a test individual is collected by using a saliva collection tube and is subjected to liquid chromatography-mass spectrometry analysis, so that the 1, 5-AG level of saliva can be accurately quantified, and pain and infection risks brought to a patient by blood detection and inaccuracy caused by cross reaction of a kit are avoided. On the other hand, the invention provides applicationthereof According to the detected saliva 1, 5-anhydroglucitol level or by combining the saliva 1, 5-anhydroglucitol level with fasting blood glucose or glycosylated hemoglobin, diabetes is screened, the diabetes screening efficiency is improved, and meanwhile, the number of OGTT people can be reduced.
Owner:SHANGHAI SIXTH PEOPLES HOSPITAL
Devices and Methods for Collecting Saliva Samples from the Oral Cavity
Provided are methods for collecting saliva from the oral cavity of a mammal comprising: placing a mouthpiece of a device comprising the mouthpiece in the oral cavity of a mammal, the mouthpiece comprising a chamber defined by front and rear inner walls and a base inner wall of the mouthpiece, each of the front and rear inner walls of the chamber comprising a plurality of openings, and a switch disposed in the mouthpiece; and the device further comprising a saliva collection reservoir, a fluid supply reservoir, a pump, and means for directing fluid through said device; activating the switch disposed in the mouthpiece to pump saliva from the oral cavity to the saliva collection reservoir for collection; deactivating the pumping of saliva to the saliva collection reservoir; and subsequently pumping fluid from the fluid supply reservoir to the mouthpiece for cleaning or treatment of the oral cavity.
Owner:JOHNSON & JOHNSON CONSUMER COPANIES
Improvements in and relating to sample collection
Sample collection apparatus and methods of sample collection are provided, for example saliva collection apparatus and methods of saliva collection. Said apparatus conveniently comprises a filter assembly and an interface for delivering material from the apparatus to an assay unit.
Owner:IMPROVEMENTS IN & RELATING TO SAMPLE COLLECTION
Saliva collector and method thereof
ActiveCN111562167AImprove collection efficiencyReduction of residuesWithdrawing sample devicesPreparing sample for investigationSaliva collectionEngineering
The invention relates to a saliva collector which comprises a bracket. A disposable saliva collecting mechanism and a liquid receiving pipe are detachably arranged on the bracket; and the upper end ofthe bracket is connected with a VR assembly through a longitudinal supporting frame. A smell emitting mechanism and a controller are also arranged on the supporting frame. The saliva collecting mechanism comprises a buccal unit and an inclined liquid collecting pipe which are connected with each other; the lower end of the interior of the liquid collecting pipe is coaxially and rotationally connected with an inner ring; a connecting piece detachably connected with the liquid receiving pipe is arranged at the lower end of the inner ring, and a spiral scraping piece for scraping saliva on the inner wall of the liquid collecting pipe is arranged at the upper end of the inner ring; the liquid receiving pipe is obliquely arranged on the bracket, a rotating assembly for driving the liquid receiving pipe to rotate axially is arranged on the bracket, and the rotating assembly is controlled by a controller; the upper end of the liquid collecting pipe is connected with a liquid injection pipe,an injection pump assembly for injecting saliva preservation liquid into the liquid injection pipe is arranged on the bracket, and the injection pump assembly is controlled by a controller. The detection process is very comfortable, the saliva collection efficiency is high, saliva residues are reduced, and the sampling success rate is guaranteed.
Owner:SHENZHEN AIMIGENE TECH CO LTD
Heating Element for Reducing Foaming During Saliva Collection
InactiveUS20140360509A1Easy to collectReduced and eliminated formationMedical devicesSnoring preventionSaliva collectionEngineering
A saliva collector comprises a reservoir and a flow path from an inlet to an outlet on the reservoir. A heating element is disposed along the flow path. The heating element applies heat to force bubbles and foam present in the air aspirated from a patient's oral cavity to collapse. The collapsed bubbles and foam evaporate or drain into the reservoir bottom as liquid saliva.
Owner:APNICURE
Apparatus for detecting and analyzing oral inner ambient of patient via oral tracheal cannula
PendingCN107095652AAccurate assessmentAccurate analysisSurgeryVaccination/ovulation diagnosticsSaliva collectionMedicine
The invention discloses an apparatus for detecting and analyzing oral inner ambient of a patient via an oral tracheal cannula; the apparatus comprises a computer, a data processor, a scanning device, a travel cart and a saliva collection device; the data processor and the scanning device are connected with the computer, and the computer, the data processor and the saliva collection device are arranged on the travel cart; during detection, medical staff holds the scanning device by hand to scan the patient's lips, gums, oral mucosae, tongue and teeth, a saliva collection bottle is used to collect the patient's saliva, the data processor analyzes scanning results and saliva results, and the medical staff provides nursing for the patient according to obtained assessing results, nursing frequency and nursing time. The apparatus allows the oral ambient to be accurately assessed and analyzed so as to formulate nursing frequency and nursing time and to assist clinical nurses in formulating a reasonable oral care plan according to the oral inner ambient of the patient, thereby decreasing chances for the patient to suffer VAP (ventilator-associated pneumonia).
Owner:JILIN UNIV FIRST HOSPITAL
Saliva collection, processing, stabilization, and storage method
ActiveUS10023903B2Microbiological testing/measurementPreparing sample for investigationSaliva sampleCell free
Owner:RGT UNIV OF CALIFORNIA
Devices and methods for collecting saliva samples from the oral cavity
Owner:JOHNSON & JOHNSON CONSUMER COPANIES
Saliva detector
PendingCN107688088AReduce viscosityReduce high tensionBiological testingSaliva collectionPositive pressure
The invention relates to a saliva detector and belongs to the field of detection equipment. The detector comprises a saliva collecting device; the saliva collecting device is provided with a first accommodating cavity, a second accommodating cavity and a test strip mounting hole communicated with the second accommodating cavity; the saliva detector also comprises a positive pressure driving deviceand a saliva filtering device assembled to the saliva collecting device; the positive pressure driving device closes the first accommodating cavity and slides along the first accommodating cavity; thesaliva filtering device is used for filtering liquid in the first accommodating cavity and is communicated with the second accommodating cavity; the liquid is used for reacting with an immune colloidal gold test strip assembled in the test strip mounting hole. The saliva detector provided by the invention integrates saliva collection, pretreatment and inspection, and has the advantages of simplestructure, convenience and quickness in operation, no limitation imposed by site and other factors, fast detection, high sensitivity, high specificity and high safety.
Owner:浙江诺迦生物科技有限公司
Diagnostic device and method for sensing hydration state of a mammalian subject
Timed sensing of collection of saliva in a liquid collection element of predetermined volumetric capacity may be used to determine salivary secretion rate, as may be indicative of state of euhydration or dehydration. Sensing of salivary flow rate may be further augmented by sensing concentration of at least one analyte in saliva (e.g., with an immunochromatographic assay performed in a lateral flow device) in order to determine a state of euhydration or dehydration. Production of saliva may be stimulated, and collected saliva may be analyzed to generate an analyte detection signal that indicative of presence and / or correlative of concentration of at least one analyte in the collected saliva to sense a state of euhydration or dehydration.
Owner:HYDRADX
Swallowing rehabilitation device for patient with cerebral infarction
The invention discloses a swallowing rehabilitation device for a patient with cerebral infarction, belonging to the technical field of rehabilitation instruments. The swallowing rehabilitation device for the patient with cerebral infarction comprises a fixing disc, a buccal device, a swallowing assisting device and a saliva collecting device, wherein the saliva collecting device, the swallowing assisting device and the buccal device are arranged on the fixing disc; the saliva collecting device is composed of a second rubber ball, a second hose and a saliva storage bottle; the fixing disc is of an annular hollow structure; water pumping openings are distributed in the peripheral face of the fixing disc and communicates with the interior of the fixing disc; one end of the second hose communicates with the interior of the fixing disc; and the other end of the second hose is connected with the second rubber ball. The swallowing rehabilitation device is simple and reasonable in structure, can effectively help a patient to carry out swallowing rehabilitation, solves the problem that when the patient carries out swallowing rehabilitation training, saliva flows out of the mouth and is difficult to clean by medical staff, and thus reduces the workload of the medical staff.
Owner:JILIN UNIV FIRST HOSPITAL
Determination method of formaldehyde-DNA adducts in saliva
InactiveCN105938124AOptimizing Chromatographic ConditionsOptimize detection conditionsComponent separationChromatographic separationHydrolysate
Provided is a determination method of formaldehyde-DNA adducts in saliva, namely the determination method of HOMe-dA and HOMe-dG in the saliva; the determination method includes the steps: collecting the saliva by using an OG-500 saliva collection tube, carrying out DNA extraction on the saliva, carrying out enzyme hydrolysis of the DNA solution, and successively adding a stable isotope internal standard, a reducing agent NaBH3CN and a DNA hydrolase; and carrying out solid-phase extraction of the hydrolysate with a Strata-X small column, collecting an eluted liquid, nitrogen-blowing to be dried at room temperature, redissolving in a methanol aqueous solution, introducing into an LC-MS / MS system, analyzing, and accurately detecting the content levels of Me-DA and Me-dG. The stable isotope is used as an internal standard quantitative analysis material, so the error caused by the sample pretreatment process can be reduced, and the selectivity, accuracy and sensitivity of the method can be improved by tandem mass spectrometry. Through selection and optimization of the chromatographic column and the elution conditions, the chromatographic separation process is relatively improved, the time of chromatographic analysis is shortened, and the consumption amount of an organic solvent is decreased.
Owner:CHINA NAT TOBACCO QUALITY SUPERVISION & TEST CENT
Monitoring cyclosporine in saliva
InactiveUS20080255765A1Promote recoveryImprove consistencyPreparing sample for investigationCyclic peptide ingredientsVenous accessBound drug
Saliva offers an alternative specimen for the therapeutic monitoring of cyclosporine (CsA) in children and patients with difficult venous access. For a highly protein-bound drug such as CsA, saliva provides a practical approach for measuring the unbound concentration. Liquid chromatography-tandem mass spectrometry (LC-MS / MS) is ideally suited for the measurement of drugs in saliva. A solid-phase extraction technique, analytic liquid chromatography over an Aqua Perfect column, maintained at 65° C., and electrospray tandem mass spectrometry were used to quantify CsA in saliva. The method used cyclosporine C (CsC) as the internal standard. Mobile phase comprised of a 97:3 voL mixture of methanol and 30 mmol / L ammonium acetate at a flow rate of 0.5 mL / min. Chromatograms using mass transitions of m / z 1219.9→m / z 1202.9 for CsA and m / z 1235.9→m / z 1218.9 for CsC were obtained. The calibration curve was linear from 1 to 300 μg / L with correlation coefficient values ranging from 0.9732 to 0.9968). The lower limit of quantification was 1 μg / L and limit of detection was 0.6 μg / L with an average extraction recovery of 84.7±2.6% for CsA and 93.7±4.4% for CsC from the saliva matrix. The accuracy of the method ranged from 92% to 104.7%, and the intra- and interim coefficients of variation were 6.9-12.2% and 8.3-12.1%, respectively. The correlation coefficient value between the CsA concentration measurements in 15 paired blood-saliva samples from kidney transplant recipients was 0.695 (P=0.006). The noninvasive and simple method of saliva collection coupled with the LC-MS / MS quantification technique for CsA analysis would generate novel data that could benefit patients undergoing CsA therapy.
Owner:BOARD OF GOVERNORS FOR HIGHER EDUCATION STATE OF RHODE ISLAND & PROVIDENCE PLANTATIONS
Animal saliva sampling equipment for veterinarians
InactiveCN113425330AAvoid harmPrevent outflowSurgeryVaccination/ovulation diagnosticsAnimal scienceCrop livestock
Owner:滑县动物疫病预防控制中心
Saliva collection and detection device
PendingCN111728647ALow costEasy to getMaterial analysis by observing effect on chemical indicatorChemiluminescene/bioluminescenceSaliva collectionEngineering
The invention discloses a saliva collection and detection device. The saliva collection and detection device comprises a casing, a collection assembly and a collection assembly, wherein the casing comprises an upper casing and a lower casing; the collection assembly is arranged on the lower casing; the detection assembly is arranged in the downstream position of the collection assembly; the collection assembly includes a three-way channel, the three-way channel includes a control channel, an inlet channel and a connecting channel which communicate with one another, the control channel is connected with a control component through the upper casing, and in the three-way channel, a three-way valve is arranged in the communication position of the control channel, the inlet channel and the connecting channel. The saliva collection and detection device has the advantages as follows: through cooperation of the three-way channel with the three-way valve, people can stably collect saliva into the device when performing saliva detection, the operation method is simple, the problem of saliva collection can be avoided, besides, the control component is arranged, saliva enters the device smoothly for detection by using pressure change, and the stability of the device is improved.
Owner:HANGZHOU INSPIRED BIOTECH INC
Respirator to Accommodate Facial Hair
PendingUS20210339056A1Small and portableLight weightBreathing filtersBreathing masksMouth piecePhysical medicine and rehabilitation
The present invention provides an exemplary respirator which may be worn effectively by individuals with beards or other non-conventional facial features such as deep scars. The respirator preferably comprises a means to either seal or plug the user's nose to prevent the user from breathing air in through their nose and also a main housing further comprising a mouth piece, a filter housing, a saliva collector, means for attaching a strap to the main housing, and a strap to keep the mask positioned properly on the user's face. The filter housing is preferably sized to accommodate a removeable dust cartridge and a removeable fume cartridge.
Owner:ALLGEIER JOSEPH R
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