31 results about "Saliva collection" patented technology

The invention belongs to the technical field of medical body fluid sample collection, and provides an integrated saliva collection filter which comprises a collection tube, a sponge rod used for collecting saliva is detachably connected in the collection tube through an extrusion part, a filter assembly is arranged at one end of the collection tube, and the liquid inlet end of the filter assembly corresponds to the sponge rod; the flexible liquid storage mechanism comprises a liquid mixing assembly, the liquid mixing assembly is connected with the collecting pipe through a connecting base, a spring microbead one-way valve assembly and a buffer liquid storage assembly are arranged in the connecting base, and the liquid outlet end of the spring microbead one-way valve assembly is communicated with the liquid mixing assembly; the liquid outlet end of the filtering assembly is communicated with the liquid mixing assembly through a spring microbead one-way valve assembly, and an automatic liquid leakage assembly is arranged between the buffer liquid storage assembly and the filtering assembly. Saliva collection, filtration and buffer solution mixing can be completed in one step, and the device is small in size, convenient to store and transport, capable of being integrally discarded after being used, environmentally friendly and efficient.

The invention discloses a biomedicine-based macaque saliva detection analyzer, and relates to the technical field of macaque saliva detection.The biomedicine-based macaque saliva detection analyzer comprises a machine body and a display screen, the display screen is arranged on the surface of the machine body, a receiver is arranged at the front end of the machine body, and the receiver detects collected saliva and displays a detection result on the display screen; the surface of the receiver is connected with an absorption pipe, clamping rods are rotatably installed on the two sides of the bottom of the machine body, an air cylinder is installed at the bottom of the machine body, macaque saliva is collected through the absorption pipe, it is ensured that a safe distance is kept between a collector and a macaque during saliva collection, and a medical sponge is used for smearing a phagostimulant to attract the macaque to actively chew; saliva secreted when the macaque chews is collected and detected in time through the absorption tube, struggling of the macaque in the saliva collection process is avoided, the personal safety of collection personnel is guaranteed, the components of the collected saliva are stable, and the accuracy of a detection result is guaranteed.

The utility model discloses a saliva sampler, which belongs to the field of animal saliva collection, and comprises a sampling piece, a collecting tube, a liquid containing tube and an isolating piece, the sampling piece is used for collecting saliva, a first containing cavity for placing the sampling piece is arranged in the collecting tube, the liquid containing tube comprises a soft liquid containing part, and the isolating piece is arranged in the liquid containing part. A second containing cavity used for containing sample preservation liquid is formed in the liquid containing part, the liquid containing part is detachably connected with the collecting pipe, the isolation piece comprises an isolation body and an easy-to-fold rod which are connected, the isolation body is connected to the open end of the second containing cavity in an isolated mode, and the easy-to-fold rod stretches into the second containing cavity. The liquid containing part is configured to be bent to push the easy-to-fold rod to tear the connecting part of the easy-to-fold rod and the isolation body when being subjected to external force so as to communicate the first containing cavity with the second containing cavity. According to the utility model, through an integrated sealed sample treatment mode, the pollution to human and environment in a pretreatment process before collection and inspection of a sample is reduced, so that the operation of an inspector is more simplified and normative.

The utility model relates to an anti-pollution saliva collection detector, and relates to the field of saliva detectors. The device comprises a detection piece and a sampling piece, the detection piece comprises a shell, the bottom surface of the shell is open, a bottom plate is assembled at the open end of the shell, a mounting groove is formed in the top surface of the bottom plate, a detection card is horizontally placed in the mounting groove, a funnel-shaped sample adding hole is formed in one side of the top surface of the shell in a penetrating manner, and the bottom surface of the shell is provided with an opening; a display hole is formed in the other side of the top surface of the shell in a penetrating manner, and the display hole corresponds to the detection card display area. The capacity of the sample adding hole is large, enough saliva samples to be detected can be collected, meanwhile, the situation that the saliva samples overflow during detection is avoided, and the detection result is affected by sample pollution possibly caused by sample overflow which pollutes test paper in other areas or makes contact with a detector shell; the hidden danger of sample overflow is solved by an enlarged containing area of a liquid collecting area of the sample adding hole and a funnel-shaped hole.

The utility model discloses a tongue blocking plate with a saliva suction function, and relates to the technical field of tongue blocking plates, the tongue blocking plate comprises a tongue blocking part, an arm part extending outwards along an arc track is integrally formed on the end face of the tongue blocking part, and a saliva collecting cavity sunken inwards is formed in one side of the tongue blocking part; the filtering part is fixedly arranged at the end part of the saliva collecting cavity; the saliva suction structure is arranged at the bottom of the saliva collection cavity, and the saliva suction structure penetrates through the arm part and is communicated with the outside. According to the spittle extractor, the arm part and the spittle collecting cavity are matched to extrude the side face of the tongue, and meanwhile, the filtering piece and the spittle extracting structure are matched, so that spittle accumulated in the spittle collecting cavity can be extracted through negative pressure provided by the outside when the tongue is extruded by the arm part; the baffle plate can absorb saliva while blocking the side wall of the tongue, so that the functionality of the tongue baffle plate in use is increased, and the convenience and efficiency of oral treatment of a patient are improved.

The invention belongs to the technical field of saliva detection, and particularly relates to a saliva acquisition electric signal monitoring system and an intelligent acquisition method.The saliva acquisition electric signal monitoring system comprises a saliva quantitative acquisition unit and a central processing unit which are electrically connected with each other; the saliva quantitative collection unit comprises a flow control module, an impedance detection module and a volume detection module; the central processing unit generates a starting instruction according to an initial signal of the impedance detection module and / or the volume detection module and sends the starting instruction to the flow control module to start collection; in the acquisition process, receiving an impedance signal and a volume signal in real time; and calculating a quality parameter for evaluating the quality of the saliva based on the impedance signal, and dynamically generating a flow regulation instruction to the flow control module based on the volume signal and the quality parameter, so that the saliva collection process meets the preset volume and quality requirements. Accurate control of the collection amount, effective improvement of the electric signal collection quality and intelligence and self-adaption of the collection process can be achieved, and the requirement for high-precision medical detection is met.

The utility model relates to saliva packaging ware technical field, and disclose a saliva enzyme control self -folding packaging ware, the rubber or silica gel sealing ring of inside preset in the existing technology generally relies on the sealing cover, the extrusion effect of screwing with the cover body is used, let sealing ring and pipe mouth adhere to form seal, the sealing function is relatively simple, the utility model discloses through setting up reinforcing component, after saliva collection good will join in the packaging pipe body, then again the sealing cover body rotation installation is to the packaging pipe body, to constitute the complete packaging ware, the saliva that adds to the packaging pipe body will continue to degrade support film body, through the stress difference of support film body degradation, make the packaging pipe body along the crease folding, the process of folding boss body moves to the sealing cover body place, finally make boss body insert to the concave platform body and take place slight deformation, to this increase the sealing performance of whole device.

This utility model discloses a saliva specimen collection device, including a collector and a collection tube. The side wall of the collector protrudes outward to form a collection chamber. The collector is provided with a saliva discharge port, which is equipped with a piston cap. A flow guide groove is provided inside the collector, and the saliva discharge port communicates with the flow guide groove, which in turn communicates with the collection chamber. The bottom surface of the flow guide groove is a flow guide slope, which gradually slopes downward from the saliva discharge port to the collection chamber. A puncture needle is installed in the collection chamber, with its lower end located at the bottom of the collection chamber. The collection tube has a plunger, and the upper end of the puncture needle is inserted into the plunger, with the upper end of the puncture needle located at the upper end of the inside of the collection tube. In this utility model, saliva is discharged from the saliva discharge port into the flow guide groove and then enters the collection chamber. By squeezing the squeeze ball, the saliva in the collection chamber is forced from the puncture needle into the collection tube, thus facilitating saliva collection.

The invention discloses an animal non-invasive sampling device and a sampling method thereof.The animal non-invasive sampling device comprises a sampling carrier unit, a basic sampling channel is formed in the surface of the sampling carrier unit, an electric rotating shaft is arranged on the inner wall of the basic sampling channel, and a transmission channel is formed in one side of the sampling carrier unit; a conveying channel is formed in the upper portion of the machine body, a storage system is arranged at one end of the conveying channel, a controller terminal is arranged on the outer side of the storage system, and an air heating system is arranged at the top end of the storage system.The device supports collection of multiple types of samples, targeted collection of four kinds of samples can be achieved by switching an excrement collection head, a hair adhesion head, a saliva trapping head and a urine suction head, and the operation is simple and convenient. The sampling head is detachable and replaceable, has an anti-pollution design to guarantee the purity of samples, adapts to a multi-habitat use scene, is equipped with three adapters, namely a trunk clamping piece, a ground fixing bracket and a cave hiding box, and can meet the deployment requirements of habitats of different animals such as tree-dwelling terrestrial cave living and the like.

A saliva-collecting materials, which enable simple and non-invasive saliva collection, was found. It can be used without any processing. That is, determination of occult blood in saliva and measurement of inflammatory lactoferrin polypeptide concentration in saliva are performed only by centrifuging the saliva-collecting materials. With the above contents, a determination method, which enables pathological classification of periodontal disease in humans and animals, is provided. Saliva is collected noninvasively by selecting and using a non-woven fabric, which can be quantitatively collected. After collecting the saliva, the non-woven fabric is set in a filter and centrifuged, and the blood components remaining on the non-woven fabric after centrifugation are visually observed to detect salivary occult blood. In addition, by measuring the I-Lf concentration in the liquid phase sample after centrifugation, it is possible to classify the periodontal disease according to the pathology.

The cleaning device comprises a box body, an operation groove is formed in the box body, a cleaning box is arranged in the operation groove, when livestock is treated, part of treatment needs to collect saliva of the livestock in advance, the device is moved to the position close to the livestock, a cotton rope is adjusted to enable the livestock to bite the cotton rope, then a rocker is rotated to collect the cotton rope, and the cleaning box is arranged in the cleaning box. Saliva is scraped under the action of a scraping plate, the saliva flows into a collecting cup through an L-shaped groove to complete saliva collection, then pressure is applied to a T-shaped pressing rod while a top cover is closed, an L-shaped sliding block moves downwards to be inserted into a cleaning box, and a sliding barrel, a first U-shaped frame, a winding roller, a cotton rope and the scraping plate are driven to be inserted into the cleaning box; the ultrasonic generator and the ultraviolet lamp are turned on for disinfection, guarantee is provided for reuse of the cotton rope, the saliva obtained next time is prevented from being polluted, the device enables collection of the livestock saliva to be easier, operation is easy, the cotton rope can be reused, cost can be reduced, time can be shortened, and working efficiency is improved.

A saliva collection device (1) for collecting a saliva sample of a user comprising handhold means (2) and an absorbent saliva collection pad (8) secured to a first end (4) to extend in a longitudinal direction (L). The collection device further comprises a pad protecting cover (10), releasably secured to the handhold means (2) in a pad covering position, in which the pad (8) is protected from deformation during a saliva sample collection procedure, and being movable relative to the handhold means (2), out of the pad covering position, to a pad releasing position, to extract the saliva sample. The protecting cover (10) further comprises a plurality of first inlet through holes (12) to provide a fluidical connection during the saliva sample collection procedure. The invention further relates to a saliva extraction device (100) for extracting a saliva sample from a saliva collection device (1) according to the invention.

The saliva suction tube comprises a saliva suction tube body, the outlet end of the saliva suction tube body is connected with a negative pressure saliva collecting box, the inlet end of the saliva suction tube body is communicated with a saliva suction plug, a plurality of holes are formed in the saliva suction plug, and the saliva suction tube body is composed of a longitudinal flexible rubber hose and a transverse flexible rubber hose. And the longitudinal flexible rubber hose and the transverse flexible rubber hose are connected through a bent pipe. The end, inserted into the oral cavity, of the saliva suction tube adopts a plurality of small holes to replace a large hole, so that negative pressure cannot be concentrated on the large hole and is dispersed by the small holes, saliva can be sucked, and damage of the negative pressure to oral mucosa can be prevented.

The application relates to the technical field of saliva collection, in particular to a saliva collector capable of preventing splashing, which comprises an outer pipe body and a contact cover installed above the outer pipe body, a sealing block is fixed to the upper inner side wall of the outer pipe body, a mouth tube is fixedly penetrated in the middle inner part of the sealing block, a self-locking sealing assembly is installed in the mouth tube, a piston assembly is connected to the lower inner part of the outer pipe body, and a flow guide cover is fixedly penetrated in the middle inner part of the piston assembly. The saliva collector capable of preventing splashing can avoid saliva splashing on the skin around the lips by spitting saliva into the mouth tube, thus avoiding the need for finding a paper towel to wipe the facial skin in the later stage, and avoiding the reduction of the collection amount of saliva samples due to splashing, so that the saliva collector can well collect the body sample saliva, facilitating the diagnosis of diseases through saliva analysis in the later stage, and thus the saliva collector can be well used in the biomedical engineering industry field.

The utility model relates to the technical field of bite devices, and discloses a gastroscope bite device set which comprises a bite tube, the bite tube is fixedly installed on the inner side of the center of a blocking piece, an elastic band is fixedly installed on the outer side of the blocking piece, and a collecting assembly is arranged on the bite tube. According to the gastroscope mouthpiece set, in order to better collect saliva and improve the applicability of the set body, the collecting assembly is arranged, when an outer ring is rotated on the outer side of an inner ring, an outer ring limiting block is made to rotate on an inner ring limiting block, so that a U-shaped frame can be conveniently rotated, the position of the U-shaped frame can be fixed, and the use is convenient. By matching with a round rod and a moving block, when a threaded sleeve is screwed to be close to a U-shaped frame on the outer side of a threaded rod, the inclined state of a flow guide arc-shaped plate can be fixed, saliva collection can be well carried out by matching with an arc-shaped clamping block and a saliva collection bag, meanwhile, the suit can also adapt to the sitting posture or the lying posture of a user, and then the applicability of the suit body can be improved.

The present application relates to the field of living extraction technology, in particular to a leech living body collection and anticoagulant activity substance synchronous extraction process, which comprises the following steps: a large number of living leeches are poured into a shunt box and are shunted by a shunt channel and then fall into a row of a plurality of object cavities; a motor drives a transfer cylinder to rotate intermittently to pick up the living leeches, and the transfer cylinder adsorbs the leeches; when the leeches fall into a plurality of collection cavities of a collection box, the leeches are attracted by a blood-containing artificial membrane and bite, and the saliva is secreted by the current stimulation of an electrode sheet; the saliva flows into a liquid collecting box and is filtered by a filter membrane in the liquid collecting box, the filtered saliva is directly introduced into a low-temperature container through a bottom port connecting pipeline of the liquid collecting box for collection, and the leech anticoagulant is obtained by centrifugal impurity removal. The funnel structure of the shunt box is combined with the flow guide sleeve to increase the single processing capacity, the air pressure adsorption and the intermittent rotation mechanism of the transfer cylinder are used to complete individual transfer, and the electrode sheet and the artificial membrane integrated stimulation system are used to achieve directional saliva collection.

The invention discloses a one-way micro-fluidic continuous detection device for oral saliva, and belongs to the technical field of saliva collection and detection, the one-way micro-fluidic continuous detection device comprises a detection shell, a saliva storage mechanism is arranged in the detection shell, the saliva storage mechanism comprises a saliva bin arranged in the detection shell, two sides of the saliva bin are respectively provided with an inlet and an outlet, and the saliva bin is communicated with a detection mechanism. Through the integrated design of the saliva storage mechanism and the detection mechanism, continuous collection and detection of oral saliva are achieved, and the complexity of traditional one-time sampling is avoided; the detection mechanism is communicated with the saliva bin to ensure the freshness of the sample; the whole structure is integrated in the detection shell, miniaturization of the device is achieved, and the device can be conveniently used in the oral cavity or in a portable mode.

The utility model relates to a saliva collector, which belongs to the technical field of oral environment and comprises a storage box and a sealing cover plate hinged to the top of the storage box, and a saliva collecting device is arranged in the storage box and comprises a mounting cylinder arranged in the storage box. The interior of the mounting cylinder is in threaded connection with a collecting cylinder extending to the bottom of the mounting cylinder, and a pressing handle is arranged at the top of the mounting cylinder. According to the saliva collector, by arranging the collecting cotton ball, saliva in the oral cavity of a collected person can be conveniently absorbed, meanwhile, saliva in the oral cavity of an animal can be conveniently collected, then by arranging a pressing handle, an extrusion plate and a filter screen, the saliva absorbed by the collecting cotton ball can be extruded out, and meanwhile the saliva flows into the collecting barrel through the filter screen to be collected; by arranging the saliva preserving fluid, saliva can be preserved for a long time, and the saliva collecting device is easy to operate and can be suitable for people and animals.

Provided is a determination method with which it is possible to find a saliva collection member achieving simple and noninvasive collection, and by simply subjecting the collection member after saliva collection to centrifugal separation without any special treatment, occult blood in saliva can be determined and inflammatory-inducing lactoferrin polypeptide concentration in the saliva can be measured, enabling disease state classification of a periodontal disease in humans and animals.　In this invention, saliva is noninvasively collected by selecting and using a nonwoven cloth capable of quantitatively collecting saliva. The nonwoven cloth after the collection is set to a filtration device to apply centrifugal separation. A blood component remaining on the nonwoven cloth after the centrifugal separation is visually observed to detect occult blood in the saliva. Moreover, by also measuring the I-Lf concentration in the liquid phase specimen after the centrifugal separation, it is possible to classify the condition into the appropriate one of periodontal disease states.

The utility model relates to the technical field of saliva collection, and discloses a multipurpose saliva collector which comprises a collecting pipe and a collecting hopper, a threaded sleeve is arranged at one end of the top of the outer side of the collecting pipe, and a filtering mechanism which is connected with the threaded sleeve and extends to the inner side of the collecting pipe is arranged on the outer side of the collecting pipe. The multipurpose saliva collector comprises a collecting hopper and a filtering mechanism, the collecting hopper is arranged at the top of the filtering mechanism, fixing mechanisms are arranged on the left side and the right side of the filtering mechanism, and a sealing mechanism connected with the top of the collecting hopper is arranged between the two fixing mechanisms. The filter mechanism is arranged to filter food residues in saliva, and then the sealing mechanism is mounted through the fixing mechanism, so that the saliva is effectively prevented from being polluted, the purpose of filtering the food residues through the filter structure is achieved, and the purpose of preventing the saliva from being polluted through the sealing structure is achieved.

A system with a saliva sampling device configured to be worn in a patient's mouth. The saliva sampling device is a polymer retainer or polymer orthodontic appliance. A saliva analysis engine is used to associate one or more analytes from one or more saliva samples with one or more health attributes. A health monitoring engine updates the patient's health profile based on the associated health attributes.

The utility model provides an integrated device for collecting and detecting saliva, and relates to the technical field of sampling and detection.A sampling head on a sampling plate is contained in the mouth for sampling, the sampling head sucks a saliva sample, after sampling is completed, the sampling plate is rotated into a containing groove in an upper plate, then a sliding cover slides relative to the upper plate, the sliding cover abuts against the sampling plate, and the saliva sample is collected and detected. The sampling plate is tightly pressed, the sampling head is extruded, so that a saliva sample sucked by the sampling head flows out to be in contact with the testing element on the lower plate, and plate running detection can be carried out, so that the technical problem that the risk of virus transmission is increased due to the split design of sample sampling and testing in the prior art is solved.

The application provides a saliva collection microfluidic device, which comprises a sampling module, a bubble capturing module, a vacuum module and a detection module. A capillary channel in the sampling module is connected with a collection chamber and a detection chamber, and the detection module is arranged in the detection chamber. Meanwhile, the vacuum module is arranged at least around the detection chamber, so that the flow of the liquid to be detected between the collection chamber and the detection chamber is smooth under the dual action of capillary force and negative pressure of the vacuum chamber. In addition, the bubble capturing module is arranged above the capillary channel to capture bubbles in the saliva sample, so as to eliminate the influence of the bubbles on the detection system. A semi-permeable membrane is arranged above the collection chamber to realize filtration pretreatment of the saliva sample, so as to reduce the viscosity of the saliva and realize filtration of interfering substances. The collection process of the saliva collection microfluidic device is efficient, easy to integrate and widely applicable, so as to improve the accuracy and sensitivity of detection. The application further provides a preparation method of the saliva collection microfluidic device.

The invention discloses a rapid sampling device for livestock and poultry respiratory diseases and a pathogenic bacterium detection method, and relates to the technical field of livestock and poultry disease sampling, the rapid sampling device comprises a syringe, a first piston disc is arranged at the position, close to the front side, of an inner cavity of the syringe, and the outer side edge of the first piston disc is attached to the side wall of the inner cavity of the syringe; a cross-shaped groove is formed in the rear end of the syringe, a cross-shaped rod is fixedly connected to the rear side of the first piston disc, the rear end of the cross-shaped rod penetrates through the cross-shaped groove and is fixedly connected with a movable disc, a collecting bag is arranged in an inner cavity of the syringe, and the front side of the first piston disc is attached to the surface of the collecting bag. Through mutual cooperation of the injection cylinder, the swab, the arc-shaped swing plate, the collection bag and other structures, the device can sample nasal cavity, throat and pharynx, nasal liquid or saliva, the swab can be conveniently mounted and dismounted, the nasal liquid or saliva can be conveniently collected and packaged, and the reuse efficiency of the device is improved.

The invention relates to a reusable salivary test device (100) for measuring a plurality of different metabolic parameters of the human body, said device comprising at least one saliva collection carrier (10) and a plurality of sensors (20); each sensor (20) comprising at least one reference electrode (RE) and at least one working electrode (WE) in direct proximity to said reference electrode, each sensor being configured to measure a subset of parameters from among said parameters, and each sensor being separate from the other sensors (20).

The utility model discloses a saliva collection and detection integrated device, a saliva collection and detection integrated device, including the funnel for the collection saliva and the detection card, the detection card includes the cavity and sets up the detection component in the cavity, the drainage port of funnel has the thread of mutual cooperation with detection card, to make the funnel with the cavity intercommunication, the drainage port of funnel is provided with check valve membrane, the utility model discloses the collector sets up the funnel type entrance, and the user directly spits saliva and can inject the detection card through the flow guide channel, exempts the user to need to contain into the cotton stick collection step. The detection card built-in test strip and maintain hydraulic stability through the overflow hole, have convenient operation, the advantages such as anti -pollution, detection reliable.

This invention belongs to the field of saliva collection technology, specifically referring to a portable negative pressure saliva collector, comprising a dual-channel assembly, a flow rate feedback assembly, a drainage and filtering assembly, an adaptive pressure regulating assembly, a collection assembly, and a baffle assembly. The dual-channel assembly is disposed on the collection assembly, the flow rate feedback assembly is slidably disposed within the dual-channel assembly, the drainage and filtering assembly is disposed on the dual-channel assembly, the adaptive pressure regulating assembly is disposed within the dual-channel assembly, and the baffle assembly is disposed on the dual-channel assembly. This invention utilizes airflow changes during partial blockage to achieve floating adjustment of the floating piston, thereby altering the pressure difference across the drainage tube. This results in automatically increasing the pressure difference when the drainage tube is blocked and automatically restoring the pressure difference after clearing.

The invention discloses application of a reagent for detecting a methylated PTPRO gene in preparation of a product for diagnosing cancers. According to the present invention, the new marker such as the methylated PTPRO gene for cancer diagnosis is found, and by detecting the expression level of the marker, the non-invasive liquid diagnosis of cancer screening can be achieved, and different lung adenocarcinoma stages can be determined. The sample detected by the invention comprises saliva. And the saliva is easy to control and not easy to coagulate, so that the influence of anticoagulation treatment on the test result is eliminated. Meanwhile, saliva collection is non-invasive, a subject is basically free of pain and discomfort, and the method has repeatability and is safe and low in cost. According to the invention, DNA is extracted from the exosome to detect the methylated PTPRO gene, and a lipid membrane of the exosome can provide good protection for components carried by the exosome, so that the detection accuracy and stability can be maintained.

The utility model provides convenient oral cavity whole saliva collector belongs to saliva analysis technical field, include: collection pipe, inflow mouth, block up disc, air vent and support. The collection pipe bottom end is blocked, and the top is open setting. Inflow mouth is located in the one side of collection pipe top and in the collection pipe intercommunication. Block up disc is slidably arranged in the collection pipe, and the block up disc is matched with the inner wall of the collection pipe and is used for collecting the saliva of the inner wall of the collection pipe through sliding. The air vent is installed on the block up disc. The support swing setting is used for the joint timing spare on the collection pipe. The utility model provides convenient oral cavity whole saliva collector structure is relatively simple, can accurately read the amount of patient oral cavity saliva in a period of time, guarantees the accuracy of the result and is convenient to use, and the practicality is stronger.