197 results about "Fluid specimen" patented technology

The invention relates to the technical field of flow measurement, in particular to a particle energy type high-frequency on-line three-phase flow metering method, which comprises the following steps: acquiring three-phase flow information, microwave signal intensity curves and environmental information parameters of a plurality of fluid samples, determining interfered categories, fitting sample curves, determining interfered characteristic fluid samples, and calculating the particle energy type high-frequency on-line three-phase flow according to the interfered characteristic fluid samples. The method comprises the following steps: acquiring a microwave signal intensity curve of a to-be-measured fluid by utilizing microwave irradiation, preliminarily determining and judging whether three-phase flow information of the to-be-measured fluid is accurate or not, determining whether to calibrate and compensate the microwave irradiation or not, selecting output information based on a comparison condition of the three-phase flow information, or giving out an abnormal early warning to a metering environment, and further, outputting the output information. According to the invention, abnormal risk identification is rapidly carried out according to the specific environment condition of the mixed fluid, the measurement mode is adaptively optimized, and the detection precision of three-phase flow information is improved.

The utility model provides a microfluid sample detection device which comprises a fluid inlet, a microfluid channel, a fluid outlet, a reaction area, a liquid collecting area, a pump body and a valve body, the valve body comprises a substrate, a double-sided colloid and a flexible diaphragm, a cavity is formed between the upper surface of the plastic substrate and the lower surface of the flexible diaphragm, the cavity is opened when the flexible diaphragm is loosened, and the cavity is closed when the flexible diaphragm is tensioned; the valve body comprises a first valve body, a second valve body, a third valve body and a fourth valve body, the second valve body and the third valve body are arranged between the pump body and the microfluid channel and located on the downstream portion of the first valve body, and the working states of the third valve body and the fourth valve body are opposite. Moreover, the parallel scheme further comprises a conductive system composed of electrodes, the conductive system at least comprises two electrodes, and the electrode sensing ends are located at the two ends of the reaction area respectively. The microfluidic sample detection device is loaded in a detection device to form a microfluidic sample detection system.

A sensor assembly for analysis of physical parameters and chemical constituents of small volume samples of bodily fluids. Disclosed herein is a sensor panel with an upper surface and a lower surface and at least one analyte sensor located on the lower surface. The sensor assembly also includes an optional adhesive layer and a contoured fluid pathway cutout. The upper surface of the adhesive layer is secured to the lower surface of the sensor panel. The sensor assembly also includes a sensor cartridge base with a fluid inlet and outlet and a contoured fluid pathway extending between the inlet and the outlet. The contoured fluid pathway mirrors the shape and span of the contoured fluid pathway cutout of the adhesive layer. As a fluid sample is input at the fluid inlet, the fluid traverses along the fluid pathway in contact with the at least one analyte sensor.

The utility model provides a microfluid sample detection device and a microfluid sample detection system. The microfluid sample detection device comprises a fluid inlet, a microfluid channel, a fluid outlet, a reaction area, a liquid collecting area, a pump body, a valve body and a lock body, the valve body comprises a substrate, a double-sided colloid and a flexible diaphragm, a cavity is formed between the upper surface of the plastic substrate and the lower surface of the flexible diaphragm, the cavity is opened when the flexible diaphragm is loosened, and the cavity is closed when the flexible diaphragm is tensioned; the valve body comprises a first valve body and a second valve body, the second valve body is arranged on the downstream of the first valve body, and the working states of the first valve body and the second valve body are opposite; the lock body is arranged on the downstream of the second valve body. Moreover, the parallel scheme further comprises a conductive system composed of electrodes, the conductive system at least comprises two electrodes, and the electrode sensing ends are located at the two ends of the reaction area respectively. The microfluidic sample detection device is loaded in a detection device to form a microfluidic sample detection system.

A method includes determining whether a variation in probe radiation intensity meets a stability criterion; directing the probe radiation through a probe, when the probe is disposed at a first position, defining a first path length L1 of the probe radiation through the fluid sample; measuring a transmitted intensity I1 of the probe radiation after passing through the fluid sample when the probe is disposed at the first position; directing the probe radiation through the probe when the probe is disposed at a second position, defining a second path length L2 of the probe radiation through the fluid sample; measuring a transmitted intensity I2 of the probe radiation after passing through the fluid sample when the probe is disposed at the second position; and determining a concentration C of a material in the fluid sample based upon L1, I1, L2, and I2, when the stability criterion is met.

A sample monitoring structure includes fluorescently-labeled hydrogel that is size-responsive to changes in one or more properties of aqueous liquid medium contacted with the sample monitoring structure. An intensity of a fluorescent emission from the sample monitoring structure changes with changes in the size of the fluorescently-labeled hydrogel. The sample monitoring structure is advantageously used in automated processing and analytical evaluation of large numbers of fluid samples over extended periods of time analytical evaluation systems, including flow cytometry systems, live cell imaging and analysis systems and parallel bioreactor system. The sample monitoring structure may be in a form of sample monitoring beads for addition to liquid media of fluid samples subjected to analytical evaluation.

A fluid flushing system includes a sampling port comprising a sampling conduit configured to dispense a sample of a fluid in the fluid routing assembly; a valve configurable in an open valve configuration, wherein the fluid is permitted to flow through the fluid flushing system, and a closed valve configuration, wherein the fluid is prohibited from flowing through the fluid flushing system; and a backflow preventer disposed between the sampling port and the valve, the backflow preventer configured to allow the fluid to flow in a first direction through the fluid flushing system towards the valve and to prevent the fluid from flowing in an opposite second direction through the fluid flushing system towards the sampling port.

A system includes a pipeline for flowing a fluid therein and a multiphase sampler fluidly coupled to the pipeline. The multiphase sampler includes an inlet to receive a fluid sample of the fluid from the pipeline, a Tesla valve(s) coupled between the pipeline and the inlet of the multiphase sampler to direct a flow of the fluid sample into a sensing section, and an outlet to return the fluid sample back into the pipeline. The sensing section includes at least one sensor to determine a water-cut of the fluid sample. A method includes flowing a fluid through a pipeline, streaming off a fluid sample from the fluid into an inlet of a multiphase sampler, determining a water-cut of the fluid sample in a sensing section of the multiphase sampler, and directing the fluid sample back into the pipeline.

The application belongs to the technical field of biology and specifically relates to a method for analyzing glycans on single extracellular vesicles in a fluid sample. The method uses magnetic nanoparticles to capture and manipulate EVs, based on the specific affinity of lectins for specific glycan structures, uses polydisperse microdroplets to separate the captured EVs, realizes local signal amplification in the droplets through enzymatic reaction, adopts fluorescence microscopy to collect images of the droplets, and thus realizes identification and analysis of the glycan components on single EVs. The preparation process of the microdroplets formed by the oscillating emulsification method of the application makes the entire detection process more simple and fast, does not require any microfluidic chip and special device, and can be completed in a centrifugal tube, and all the microdroplets are generated in parallel and quickly, and the amount of microdroplets can be flexibly expanded. Moreover, compared with the traditional ELISA, the method has high sensitivity, low detection limit and small sample consumption.

The present invention provides a device for detecting a substance to be analyzed in a fluid sample, the device comprising: a housing having an upper card and a lower card, the lower card being provided with a support structure for supporting a lateral flow test element, the lateral flow test element being provided for detecting a substance to be analyzed in a liquid sample, the supporting structure comprises an applying pad for receiving a liquid sample, the supporting structure comprises a supporting mechanism for supporting the whole sample applying pad, and the partial structure for supporting the sample applying pad is inclined.

The present invention provides a carrier, which includes a channel for accommodating a test strip. One end of the channel is closed and the other end has an opening, and the fluid sample to be detected can enter the channel through the opening. Wherein, a flood prevention structure is included in the channel. By changing the channel in the carrier structure, the flood phenomenon of the test strip can be prevented and the error rate can be reduced.

The present disclosure relates to a sensor device for an analyser apparatus configured to analyse parameters of medical fluid samples. The sensor device comprises: a measurement chamber defining an interior volume for receiving a fluid to be analysed; a chamber inlet and a chamber outlet, each respectively providing a respective fluid passage to the interior volume; a reference electrode arranged in fluid communication with the interior volume; and one or more ion-selective analyte sensors, wherein each of the analyte sensors comprises a sensor electrode and an ion-selective sensor membrane arranged between the interior volume and the sensor electrode. The sensor device further comprises a sulfur-reactive element arranged in fluid communication with the interior volume to thereby fluidly contact the fluid to be analysed when the interior volume receives the fluid to be analysed. The disclosure further relates to an analyser apparatus and use of a sulfur-reactive element.

The invention belongs to the technical field of sampling, and particularly relates to a ball valve convenient for online maintenance, which comprises a sampling ball valve, the sampling ball valve comprises a connecting shell and a sampling shell mounted below the connecting shell, a sampling bottle is movably mounted below the sampling shell, and an upper sealing ring and a lower sealing ring are fixedly mounted at the inner top of a sampling cavity. A valve ball is rotatably installed between the upper sealing ring and the lower sealing ring, a water inlet and outlet pipe is fixedly installed on the two sides of the sampling shell, the valve ball comprises a fluid passing body and an abutting cover, and through rotation of the valve ball, fluid in the fluid passing body can enter a sampling bottle installed on the sampling shell through a sampling cavity and the valve ball to be subjected to subsequent detection work; purified water enters from one group of water inlet and outlet pipes and then flows out from the other group of water inlet and outlet pipes through the valve ball and the interior of the sampling cavity where the valve ball is located, so that the originally retained fluid is reduced, the online cleaning and maintenance function is deepened, and the quality of a fluid sample sampled next time is ensured.

The present application provides a kind of microfluidic sample detection device and microfluidic sample detection system, and detection equipment and microfluidic detection device electrode electrically / signal connection forms microfluidic sample detection system.Microfluidic sample detection device, including fluid inlet, microfluidic channel and fluid outlet, and reaction zone, liquid collection area, first pump body, first valve body, second valve body, third valve body and fourth valve body, the working state of third valve body and fourth valve body is opposite.First pump body, when being communicated with microfluidic channel, provides driving force for the flow of microfluidic sample;Second valve body, it is located between first pump body and microfluidic channel, and located downstream of first valve body;Third valve body, it is located between first pump body and microfluidic channel, and located downstream of second valve body.First pump body can be communicated with microfluidic channel by second valve body or / and third valve body.

Systems and methods for analysing a fluid are disclosed, including a fluid sample delivery apparatus. The system includes a sensing element configured to respond to at least one analyte in a sample of fluid. A detector is provided, configured to sense the response to the analyte by the sensing element. The fluid sample delivery apparatus includes a dosage needle configured to deliver the sample of fluid to the sensing element, at least one pump configured to control flow of fluid through the dosage needle, and at least one actuator configured to move the dosage needle relative to the sensing element. At least one controller is provided, configured to control the at least one pump and the at least one actuator.

A container assembly for collecting a fluid specimen including a collection container having a first end, a second end, and a sidewall extending therebetween and defining a chamber for receiving the fluid specimen. The container assembly may include a container lid couplable to the collection container to at least partially close the first end thereof. The container lid may include a sealing interface configured to at least partially contact the collection container when the container lid is coupled to the collection container. The sealing interface may include a textured sealing surface region configured to allow air into or out of the container assembly when the container lid is coupled to the collection container, while maintaining a substantially fluid-tight seal between the container lid and the collection container.

The disposable fluid sampling device comprises a body fluid sampling device, and optionally comprises a body fluid sampling device for automatic sampling; and optionally an analysis device for analyzing the fluid using one or more droplets of the sampled fluid; the invention relates to a device for analyzing a fluid sample, comprising at least one vacuum tube or vacuum source, and an interface for at least one sample tube or medical analysis tube adapted to be filled with a fluid sample for analysis at a point of care or in a medical laboratory, the device comprising an interface for at least one vacuum tube or vacuum source, the vacuum tube or vacuum source is adapted to provide a suction force required to fill the at least one sample tube with a fluid.

A method for delivering a fluid sample through a channel of a diagnostic consumable is disclosed. The method includes receiving the diagnostic consumable in a reader comprising a delivery system, operatively connecting the delivery system to the channel, and applying pressure pulses to the channel at a predetermined frequency. A reader for reading a diagnostic consumable is also disclosed.

Apparatuses and methods related to a point-of-care portable assay device are described herein. In an embodiment, a device for analyzing a fluid sample includes a fluid actuation source configured to engage a port on a test card. The fluid actuation source is configured to apply pressure to the port to cause the fluid sample to move along a microchannel of the test card to enable one or more assays to be performed. The device also includes a controller configured to receive an indication as to which one or more assays are to be performed, cause the fluid actuation source to move the fluid sample into one or more regions on the test card, cause a plurality of electrical contacts to provide power to the test card for performing the one or more assays, and determine at least one test result based on the performed assays.

In an embodiment, a fluid concentration measurement system is disclosed. The measurement system comprises a sensor device comprising a sampling and measurement unit that is configured for insertion into a fluid stream. The sampling and measurement unit is configured to obtain a fluid sample from the fluid stream and to mix a reagent with the fluid sample to form a mixed sample. The sensor device further comprises a light source that is configured to illuminate the mixed sample and an optical sensor. The optical sensor is configured to receive light from the mixed sample based at least in part on the illumination of the mixed sample and generate sensor data based on the received light. The measurement system further comprises at least one processor that is configured to obtain the sensor data and determine a concentration of a target analyte in the fluid stream based on the sensor data.

A hematology analyzer for analyzing a fluid sample and comprising a frame body defining a first axis (X-X′) and a second axis (Y-Y′), a cartridge unit having a first compartment containing the fluid sample and a second compartment containing a cleaning fluid, a fluid analysis module comprising a first probe and a second probe, a first transmission unit configured to hold and move the cartridge unit along the first axis (X-X′) to align the first compartment and the second compartment with the first probe and the second probe, respectively, and a second transmission unit configured to move the fluid analysis module along the second axis (Y-Y′) such that the first probe and the second probe pierce the first compartment and the second compartment, respectively.

Monitoring device, system and method for detecting an element in a fluid. The monitoring device (1) comprises a particle sensor (139), a VOC sensor (132) that includes a compartment (131), a lens (133) and a laser emitter (135) and a concave mirror (134) optically coupled with the lens (133). The particle sensor (139) electrostatically filters particles in a fluid sample (101b), provides a filtered fluid sample (101a) to the compartment (131), and provides particle data in the fluid sample. The concave mirror (134) concentrates laser light refracted by the filtered fluid sample (101a) in the compartment (131) and directs said concentrated laser light to a measurement area (132a) of the VOC sensor (132). The VOC sensor (132) collects spectrophotometric data (102a) based on Raman spectrography on the filtered fluid sample (101a) from the compartment (131).

An apparatus and method for image analysis of a fluid sample on a test card are disclosed. An example apparatus for analyzing a fluid sample includes a camera imaging device configured to record a plurality of images of the fluid sample while located within a target zone of a fluid microchannel of a test card. The example apparatus also includes a controller configured to perform a cytometry analysis on the fluid sample to determine whether the fluid sample tests positive or negative for a bacteria or virus.

The present invention provides a device for collecting and detecting analyte in a fluid sample, the device comprising: a fluid sample collecting element; a test element carrier; and a retaining element, wherein the test element carrier is located in the retaining element. In a preferred embodiment, the fluid sample collecting element comprises an absorbing element and a grasping portion, wherein the grasping portion comprises a retaining structure that cooperates with the retaining element to allow the fluid sample collecting element to be separated from the retaining element.

A bioelectrical sensor for detecting one or more pathogens in a fluid sample is provided. The bioelectrical sensor receives a fluid sample comprising one or more pathogens, and detects the one or more pathogens using a series of chemical reactions. The series of chemical reactions include a detection step in which a detector organism detects a pathogen upon coming into contact with and / or to within a certain proximity of the pathogen, and a reporting step in which a reporter organism responds to the detection by generating an electrical signal comprising information about the detected pathogen. The electrical signal may then be transmitted to a computing device, which may identify the pathogen by mapping the generated electrical signal to a known pathogen.

Various devices, systems and methods for detecting infectious agents or determining a susceptibility of an infectious agent to an anti-infective are described herein. One example method comprises introducing a fluid sample to a surface; exposing the surface to a solution; sampling the solution after exposing the solution to the surface; and detecting a change in an electrical characteristic of a sensing device exposed to the solution sampled corresponding to a presence of the infectious agent in the fluid sample.

Attachment devices for releasable coupling to a fluid dispensing device are provided. The attachment devices include a hollow body comprising a collar portion and a barrel portion extending from the collar portion. The barrel portion has an end portion having a closed end and at least one side opening. Longitudinally positioned along the exterior surface of the barrel is at least one rib branching upwards into two rib branches. When coupled to a fluid dispensing device, the assembly can be used to obtain a fluid sample. Thereafter the assembly can be used to dispense the fluid sample into an assay vessel so that the fluid sample can then be assayed. Methods for operating the attachment devices, and assemblies containing the attachment devices are also provided.

An endotracheal tube apparatus is provided which comprises an endotracheal tube insertable into a trachea of a patient, wherein the endotracheal tube has a sidewall and includes a first passageway, wherein the first passageway is a ventilation passageway to provide ventilation to the patient; a fluid sampling port connected to the sidewall of the endotracheal tube; the fluid sampling port including a fluid sampling passageway, the fluid sampling passageway to obtain a fluid sample comprising one or more gases exhaled from the patient; and the fluid sampling port including a connector to connect the fluid sampling port to an analyzer to detect a presence of carbon dioxide gas in the fluid sample.