Chinese medicinal compound preparation for osteoporosis and preparation method thereof

A technology for osteoporosis and compound preparations, applied in the medical field, can solve problems such as unrelated research, achieve the effects of improving bone quality, treating and preventing osteoporosis, and promoting bone tissue formation

Inactive Publication Date: 2018-11-02
FIRST AFFILIATED HOSPITAL GUIYANG UNIV OF CHINESE MEDICINE
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] Although Yaobi Zhitong decoction can regulate the activation of BMP pathway, there is no relevant research on the mechanism of its activation of BMP-2 / Smad pathway to promote osteogenic differentiation.

Method used

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  • Chinese medicinal compound preparation for osteoporosis and preparation method thereof

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Embodiment Construction

[0027] In order to make the object, technical solution and advantages of the present invention more clear, the present invention will be further described in detail below in conjunction with the examples. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.

[0028] The traditional Chinese medicine compound preparation for osteoporosis provided by the embodiments of the present invention consists of 400-600 parts of drynariae, 300-500 parts of Clematis, 400-600 parts of Angelica sinensis, 300-500 parts of Rhizoma Chuanxiong, 400-600 parts of peony, 300-500 parts of corydalis, 280-380 parts of dog spine, 280-380 parts of Eucommia ulmoides and 100-180 parts of licorice.

[0029] The traditional Chinese medicine compound preparation for osteoporosis provided by the embodiment of the present invention consists of 420 parts by weight of drynariae, 333 parts of clematis, 420 parts of ...

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Abstract

Belonging to the field of medical technology, the invention discloses a Chinese medicinal compound preparation for osteoporosis and a preparation method thereof. The Chinese medicinal compound preparation for osteoporosis is composed of, by weight part, drynaria rhizome, clematis root, Chinese angelica, Ligusticum wallichii, radix paeoniae rubra, rhizoma corydalis, rhizoma cibotii, eucommia and licorice. The invention also discloses a preparation method. By adopting the technologies and methods of modern cytobiology and molecular biology, from the aspects of molecule, cell, tissue, overall animal level and the like, the invention proves that waist impediment analgetic decoction can regulate BMP-2 / Smad pathway to inhibit senile osteoporosis. The successful completion of the invention can provide a new strategy for prevention and treatment of senile osteoporosis.

Description

technical field [0001] The invention belongs to the technical field of medicine, and mainly relates to a Chinese medicine compound preparation for osteoporosis and a preparation method thereof. Background technique [0002] At present, the existing technologies commonly used in the industry are as follows: [0003] Osteoporosis (Osteoporosis, OP) is a systemic skeletal disease characterized by a decrease in bone tissue content and a degeneration of bone microstructure caused by a variety of reasons, resulting in increased fragility and reduced strength of the bone, leading to a systemic skeletal disorder that is prone to fractures. disease. In particular, osteoporosis caused by senile diabetes and postmenopausal osteoporosis have become the biggest victims of the disease. At present, the pathogenesis of osteoporosis involves multiple levels and links, including osteoblast differentiation, bone microstructural degeneration, and osteopenia. None of the existing treatment me...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/716A61P19/10
CPCA61K36/12A61K36/126A61K36/232A61K36/236A61K36/46A61K36/484A61K36/65A61K36/66A61K36/71A61K36/716A61K2236/331A61K2236/39A61P19/10A61K2300/00
Inventor 沈骏
Owner FIRST AFFILIATED HOSPITAL GUIYANG UNIV OF CHINESE MEDICINE
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