7results about How to "Avoid combining" patented technology

This invention relates to the field of halloysite (HNTs) applications and discloses a preparation process for a brain delivery system based on halloysite HNTs. The process involves co-incubating halloysite with Aβ fibers (senile plaques) in vitro to provide the halloysite's role in degrading Aβ fibers (senile plaques). The halloysite undergoes tubularization and amino modification, followed by NHS-PEG processing. 5000 -MAL binds the RVG29 peptide to the surface of HNTs; NHS-PEG 5000 The NHS group in the MAL reacts with the amino group of halloysite after amination to form a stable amide bond, and the MAL group reacts with the thiol group of the RVG29 peptide to form a stable thioether bond, thereby achieving the modification of halloysite with the RVG29 peptide. Utilizing the positive charge of the halloysite lumen, negatively charged siRNA is directly loaded into the tube through electrostatic interaction to prepare SH-RVG / siRIPK1 material, which has the dual effects of degrading Aβ fibers (senile plaques) and slowing down neuronal death, and can be used for the treatment of AD.

This invention belongs to the field of detection technology, specifically relating to a method for detecting the heavy metal content in food additives. The detection method includes the following steps: (1) sample pretreatment; (2) preparing a series of heavy metal standard solutions of different concentrations, testing their net strength using an ICP-MS instrument, and obtaining a standard working curve; (3) testing the net strength of the sample solution and blank solution using an ICP-MS instrument, and obtaining the concentration of heavy metals in the food additives by combining the standard working curves, and further obtaining the content of heavy metals in the food additives. The detection method of this invention can be used to detect the heavy metal arsenic in compound meat product thickeners. Through enzymatic hydrolysis-assisted extraction and ultrasonic synergistic extraction, gradient ultrasound combined with temperature control is used to further destroy the sample structure and improve the arsenic dissolution efficiency; EDTA and citric acid are used to complex metal ions, and multiple components synergistically reduce the fixation effect of other ions on arsenic. Through synergistic effect, the accuracy of the detection results is improved.

The invention relates to the technical field of heavy oil thermal recovery reagents, in particular to a strong emulsion system for assisting viscosity reduction and plug removal as well as a preparation method and application thereof. The strong emulsion system is prepared from the following raw materials in percentage by mass: 2%-10% of sorbitol dehydrated ester mixture, 5%-10% of 120 # solvent oil, 3%-6% of alcohol ether carboxylate, 0.5%-1.0% of ethylene glycol tert-butyl ether, 5%-10% of organic acid, 3%-6% of polybasic polycarboxylic acid, 3%-6% of villiaumite, 1%-2% of imidazoline corrosion inhibitor, 1.0%-3.0% of functional additive and 46%-76% of water. The strong emulsion system can perform deep plug removal on an underground reservoir and prevent organic acid of the strong emulsion system from being combined with heavy components in the thick oil so as to avoid formation of acid sludge, so that the plug removal effect of the strong emulsion system can be improved.

The application belongs to the technical field of biological detection, and aims at solving the single color change mode and poor sensitivity of the current ELISA kit, and provides CMO nano-oxidase, a CMO-OVA-MC-LR probe, a kit, a preparation method and application thereof.The CMO nano-oxidase is a raspberry-shaped Co-doped Mn3O4 oxidase, the nano-oxidase is a two-heterojunction CMO of Co3O4 and Mn3O4 synthesized by one-pot hydrothermal method, and the particle size is 110-140 nm.The detection limit of the enzyme-linked immunosorbent kit constructed by the application for microcystin LR (MC-LR) is 0.505 ng / mL, and the quantitative range is 0.195-100 ng / mL.Benefiting from the strong catalytic activity and good biocompatibility of the nano-enzyme, the label and signal response mode open up a new way for the sensitivity improvement of the immunosensor determination, and are conducive to further expanding the application of the immunosensor.

The utility model discloses a kind of dioxin processing devices of waste incineration, including heat exchange mechanism, dust removal mechanism, incineration mechanism, cooling mechanism, spraying mechanism and activated carbon adsorption mechanism which are sequentially arranged, characterized in that, the incineration mechanism includes incinerator (1), incinerator (1) is sequentially provided with primary incineration bin (2) and secondary incineration bin (3) with waste gas operating direction, primary incineration bin (2) front end is equipped with atomizing oil atomizer (4) and the air inlet pipe (5) directly connected with the air outlet of dust removal mechanism, the air inlet of atomizing oil atomizer (4) is connected with the air outlet of dust removal mechanism, atomizing oil atomizer (4) oil inlet is connected with oil tank (6), secondary incineration bin (3) side is equipped with combustible gas inlet (7), primary incineration bin (2) and secondary incineration bin (3) bottom are equipped with oxygen supply pipe (8).It can improve dioxin reaction effect, and reduce the possibility of generating again.

The utility model provides glue-free formaldehyde-removing composite cloth and a glue-free formaldehyde-removing mattress. The glue-free formaldehyde-removing composite cloth comprises a first cloth layer, a second cloth layer and a formaldehyde catalytic powder layer located between the first cloth layer and the second cloth layer, wherein a plurality of hot melting bonding points are arranged on one side, facing the second cloth layer, of the first cloth layer, and the hot melting bonding points are bonded with the second cloth layer in a hot melting manner, so that the formaldehyde catalytic powder layer is sealed between the first cloth layer and the second cloth layer. According to the utility model, large-area gluing is replaced by the point-shaped hot melting combination part, so that the influence of an adhesive on the contact area of catalytic powder is avoided, the powder can be effectively sealed, catalytic components are prevented from falling off, the formaldehyde removal service life is lasting and efficient, and meanwhile, the production efficiency is improved.

The application discloses a kind of azahemicyanine dyes and application thereof, compared with the dye similar to the function of novel azahemicyanine dye molecule provided by the application, the application can effectively prevent the non-specific combination of serum albumin and hemicyanine dye, and the stability, fluorescence quantum yield and stoke shift of the hemicyanine dye are enhanced;The dye synthesis step provided by the application is simple, easy to purify, and has high yield;By introducing six-membered heterocyclic ring into the side chain of azahemicyanine dye, the combination with protein is effectively avoided, the false positive interference of serum albumin on dye fluorescence signal is excluded, and kidney targeting is realized, and the high fidelity of imaging is improved;The probe NA-H2S2 synthesized based on the dye NA-6 provided by the application is used for rapid detection of the change of H2S2 concentration;The synthesis step of the dye molecule is simple, easy to purify, has excellent imaging performance, fluorescence signal is not interfered by serum albumin, and is suitable for high-fidelity imaging of kidney.