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89results about How to "Prevent embolism" patented technology

Sticky dilatation balloon and methods of using

The present invention involves an expandable element with an outer sticky surface. The expandable element may be in the form of a balloon with deflated and inflated configurations. The expandable element serves to both dilate a lumen in a blood vessel thereby opening it and to exert force upon the sticky surface in order to press it into apposition against a vessel wall. The outer sticky surface may be provided directly upon the expandable element or on a separate outer sheath that conforms to and follows the contours of the expandable element. The sticky surface may take the form of a biochemical composition and / or a mechanically abrasive structure such as microhooks, hairs, mesh netting, etc. Optionally, additional expandable elements may be provided proximal and distal to the main element to occlude blood flow on either side of a lesion in order to better trap emboli for collection.
Owner:SPECIALIZED VASCULAR TECH

Embolic protection apparatus with vasodilator coating

An apparatus for temporary prevention of embolization in a human blood vessel. The apparatus comprises a body that is transformable between a radially collapsed configuration and a radially expanded configuration sized and shaped for sealing against an inner wall of the vessel to at least partially obstruct fluid flowing there through, the body having a vasodilator coating.
Owner:MEDTRONIC VASCULAR INC

Preparation method of biodegradable medicine composite macromolecular scaffold material

A preparation method of biodegradable medicine-compounded macromolecular scaffolding material includes the following steps: dissolving macromolecular polylactic acid, polycaprolactone and restenosis-resisting medicine in the solvent, pouring the prepared solution into a container for film-forming, making the said film into filament, dipping the said filament in the mixed solution prepared with L-lactic acid and diglycolide copolymer, solvent and restenosis-resisting medicine and drying in the air or freeze-drying, then soaking the said filament in anticoagulative solution, drying in the air, making filament wind round the mould, thermosetting and forming so as to obtain the invented product. The described solvent is chloroform, 1,4-dioxane and dimethyl sulfoxide, the restenosis-resisting medicine is taxol, taxadter, arotinoid ethylester, probucol, dectan and cilomosi, and the anticoagulative solution is prepared with carboxylated sulfurnic aid esterified chitin aqueos solution or heparin sodium aqueos solution and acetone through the process of mixing and solvation reaction.
Owner:TSINGHUA UNIV +1

Temporary valve and valve-filter

ActiveUS20140277096A1Reduce time pressurePreventing wide open regurgitationHeart valvesDilatorsBlood flowBiomedical engineering
A temporary percutaneous valve-filter device having valve portions non-porous to blood and filter portions non-porous to emboli but at least in part porous to blood. In one embodiment, the device has a substantially flat valve unit and a substantially flat filter unit. In another embodiment, the device has at least one open umbrella deployed configuration. In one aspect, the device has a unitary construction with one umbrella canopy with one or more filter areas with flaps allowing unidirectional blood flow. In another aspect, the device has a valve unit and filter unit, the umbrella canopies oriented in opposite directions, and the valve unit “closes” and opens to allow blood to flow to one direction. Also provided is a temporary valve system, including a core having an inverted delivery configuration and everted deployed configuration, that may be used with or without a filter unit, and a method of deployment.
Owner:VALVE MEDICAL

Method and apparatus for vascular access

A method and apparatus is described that facilitates appropriate placement of a closure device and allows ease of placement with repeated access without bleeding. A suitable biocompatible polymer diaphragm such as silicone or nipple is place on the adventitia of the vessel through a small cutdown incision. The puncture surface is a diaphragm that functions as a self-sealing valve. For embodiments designed for small catheter access such as 4 to 9 Fr, this may be a polymer that elastically seals around the puncture once the catheter is removed. Especially for larger access catheters, such as 10 French to 24 French, a preformed aperture or slit may be cut into the material, allowing controlled and atraumatic penetration of the device and artery. The sealing element may also be fixed to the outside wall of the vessel with holdfasts through a method that facilitates percutaneous delivery through the use of a guiding wire. A method and apparatus is also described that minimizes the potential migration of emboli generated upstream from the access site, an anchoring cannula and method for facilitating localizing of the access device.
Owner:CHANG DAVID W

Flexible releasing conveying system

InactiveCN101496730AReduce the impact of real stateAvoid deathStentsSurgeryTransport engineeringDelivery system
The invention relates to a transportation device for inputting an intervention apparatus into a selected area of a human body. A soft disengagement transportation system comprises a transportation pin, and a transportation component for pushing the intervention apparatus to an affected part, wherein the transportation component in the transportation pin comprises a soft connecting component which is movably connected with the intervention apparatus. The transportation device is provided with the soft connecting component which is still connected with the intervention apparatus and maintains soft connection with the intervention apparatus after a rigidity connecting component disengages, the effect of tractive force on the real state of the intervention apparatus is greatly reduced; at the same time, if an intervention product falls off or the state of the product is not ideal, the device can withdraw the intervention apparatus through the soft connecting component and avoid the occurrence of death or embolism and other serious complication of a patient caused by the shedding of a blocked device.
Owner:LIFETECH SCIENTIFIC (SHENZHEN) CO LTD

Valve replacement devices and methods

An embolic material blocking catheter includes a handle assembly, an elongated element having a lumen, and a deployable embolic material blocking element. The embolic material blocking catheter is configured to accommodate insertion of a treatment catheter into the lumen to position a treatment device distal to the embolic material blocking element for administering a treatment at a treatment site and / or convey embolic material blocked by the embolic material blocking element for extraction from the patient.
Owner:EMSTOP INC

Oval Aortic Valve

An oval valve for use in transcutaneous aortic (TAVI) or mitral valve implantation or for direct access valve implantation. The oval leaflet frame or stent provides a better seal with the oval native annulus to reduce perivalvular leaks. The valve leaflets are a bileaflet configuration to provide improved leaflet coaptation independent of the amount of ovality of the native valve annulus. The bileaflet configuration is less dependent upon the diameter and perimeter of the native valve annulus and provides leaflet coaptation without intravalvular leakage.
Owner:DRASLER WILLIAM JOSEPH

Walnut oil fat emulsion and manufacturing method thereof

The invention relates to walnut oil intralipid and process for preparation, belonging to the technical field of food and drug. The formulation comprises pure walnut oil, refining lecithin, pure glycerin, caustic soda and pyrogen-free pure water. The basic preparing procedures are as follows: pure walnut oil, refining lecithin, glycerin and water are vigorously stirred into primary milk and the pH value of the primary milk is adjusted to 7.5-8.5 through little caustic soda solution, and then high-pressured and homogenized, filtered by a filter, bottled, sealed and sterilized. The walnut oil intralipid is an artificial chyle product which is prepared by simulating natural chyle granules existing in blood and can be intravenously injected as 'parenteral nutrient solution' to rescue lives of some severe patients, (such as severely burned patients, traffic accident injured patients, patients with great operations, patients with advanced tumor and cachexia, etc.) and furthermore can be used for complementarily curing some dystrophic diseases and also can be orally taken as nutrition supplementary and auxiliary treatment. The invention can increase essential energy for body metabolism, provide biological film for body and essential 'polyunsaturated fatty acid' for biologically active substance metabolism, and prevent and correct deficiency of essential fatty acid for body. The invention has a plurality of therapeutic functions of blood sugar reduction, anti-oxidative damage, anti-anaphylaxis, anti-cell senescence, and anti-cardiovascular hardness and the like, and provides a new direct and convenient way through which edible and medical walnut effective component can enter human body.
Owner:陈朝银

Exerciser beneficial for ankle pump exercises of patient with foot drop

The invention discloses an exerciser beneficial for ankle pump exercises of a patient with foot drop. The exerciser comprises a base which is horizontally arranged, wherein one end, in a length direction, of the base is provided with a supporting plate capable of rotating; a slide rail is arranged in a length direction of the supporting plate; a connecting plate is connected onto the slide rail in a sliding manner; an exercising frame is further arranged between the base and the supporting plate; one end, in a length direction, of the exercising frame is connected with the connecting plate; the other end of the exercising frame is rotatably connected with the base; one end, away from the base, of the supporting plate is provided with an operating rod used for the patient to operate; and a fixator for fixing feet of the patient is further arranged on the exercising frame. The exerciser can effectively prevent formation of thrombus, which causes embolisms of the heart, the brain and lungs, of lower extremity veins from forming, and is further beneficial for recovering limb functions of the lower limbs, so that the patient with foot drop can conveniently carry out rehabilitation training by himself or herself, and can actively participate in own limb rehabilitation of him or her, and therefore, the exerciser is high in comfort level, the cost is reduced, and the working efficiency is improved.
Owner:贾艳

Face filling agent composition for injection type cosmetic plastic surgery and preparation method of face filling agent composition

The invention discloses a face filling agent composition for injection type cosmetic plastic surgery and a preparation method of the face filling agent composition, relates to a ace filling agent composition for cosmetic plastic surgery and a preparation method of the face filling agent composition, and aims to solve the problems that conventional cross-linked hyaluronic acid is poor in cross-linking effect, a user has red and swelling inflammation, potential safety hazards can be caused, not only is a skin repairing effect not achieved, but also vascular thrombosis can be possibly caused. Theface filling agent composition for injection type cosmetic plastic surgery comprises a cross-linked hyaluronic acid composite gel, hydroxyapatite micro particles, collagen powder, cellulose ethers, an epimedium herb extract, a white peony root extract and an injection aqueous solution. The method comprises the following steps: I, weighing materials; and II, performing mixing and sterilization. The face filling agent composition for injection type cosmetic plastic surgery, which is prepared by the invention, has a use mode of being injected into dermis of a part to be filled, of a face. The invention obtains the face filling agent composition for injection type cosmetic plastic surgery.
Owner:陈勇

Safety infusion set on basis of bubble point pressure principle

The invention relates to the technical field of medical instruments, in particular to a safety infusion set on the basis of the bubble point pressure principle. The technical scheme includes that a liquid medicine filter medium with the bubble point value ranging from 7.85 to 25kPa is selected according to the bubble point pressure principle, infusion of liquid medicine is stopped automatically according to the characteristics of the liquid medicine filter medium when the liquid medicine in the infusion set drips off, so that air can be prevented from entering an infusion tube and safety is guaranteed. Further, an exhaust tube extending to an inner cavity of a dropper is arranged in the dropper, a filter medium capable of exhausting air but not draining liquid is arranged at the extending end of the exhaust tube, so that automatic exhaust is realized significantly and safely and the high-efficiency and safe air separation effect is realized since the infusion set is combined with the bubble point pressure principle.
Owner:李林风

Small and medium diameter artificial blood vessel with adjustable pressure and flow

InactiveCN102302387ASuitable for shunt selectionResilientBlood vesselsRemote controlMedicine
The invention discloses a small and medium diameter artificial blood vessel with adjustable pressure and flow. The artificial blood vessel comprises a blood vessel wall, a blood vessel cavity is in the blood vessel wall, and a pressure and flow controller capable of adjusting the diameter of the artificial blood vessel is arranged outside the artificial blood vessel. Concave and convex grains are arranged on the blood vessel wall. The pressure and flow controller comprises a fixed shell and a control spring, wherein the fixed shell takes the shape of a cylindrical structure, and the control spring is configured to be a cylindrical structure, the control spring is arranged in the fixed shell and sleeved outside of the blood vessel wall of the artificial blood vessel, the control spring is provided with a limit spring handle for adjusting the diameter of the blood vessel, and the spring handle passes through a control frame. The fixed shell is provided with position fixing holes, and the control spring is provided with position fixing holes. The fixed shell is provided with a fastener. The pressure and flow controller comprises a mechanical pressure and flow controller, an in-vitro remote control pressure and flow controller and an in-vivo induction pressure and flow controller. The blood vessel is applicable to controlling the size of fractional flow according to an induced pressure of a hepatic portal vein after a portosystemic blood vessel is anastomosed and shunted so as to ensure the hepatic portal vein perfusion pressure required by individuals.
Owner:SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY

Infusion apparatus special for indwelling catheter

The invention belongs to the technical field of medical apparatuses and instruments, and discloses an infusion apparatus special for an indwelling catheter. The infusion apparatus is composed of an infusion assembly and a positive pressure assembly, wherein the infusion assembly has the pure infusion performance or additional other performances, and the positive pressure assembly has the thrombus preventing performance. When connected with an indwelling needle for infusion and disengaged from the infusion apparatus at the end of infusion, the positive pressure assembly can be separated from the infusion assembly and can indwell on the indwelling catheter, long-acting micro slow-release infusion is achieved by means of liquid medicine left over in a positive pressure cavity of the positive pressure assembly, the indwelling catheter is made to maintain positive pressure for a long time, blood backflow can be effectively prevented, and the problem that indwelling catheter coagulation or thrombus blockage can be effectively prevented in a long-acting mode. By the adoption of the infusion apparatus, the indwelling positive pressure assembly is detached to be discarded before next infusion is carried out, and then a new infusion apparatus is connected to the indwelling catheter to be used.
Owner:李宜

Degradable chitosan-based composite hemostatic film

The invention discloses a degradable chitosan-based composite hemostatic film which comprises a base material layer and a functional layer, and is characterized in that the base material layer is degradable fiber cloth; the functional layer is composite hydrogel prepared from modified chitosan, polyethylene glycol 2000, gelatin, xanthan gum, Ag / Fe2O3 magnetic nanoparticles, forged ophicalcitum and oleamide, and the functional layer is combined with the base material layer through polydopamine. The degradable chitosan-based composite hemostatic film provided by the invention has the advantages of softness, air permeability, high safety, good mechanical properties, strong water absorption and retention capacity, capability of being tightly attached to a wound, easiness in stripping, hemostasis, good anti-infection effect and no side effect of vascular embolism.
Owner:HENAN YADU IND

Collagen fruit jelly and preparation method thereof

The invention discloses collagen fruit jelly and a preparation method thereof. Each 1000 bags of products of the collagen fruit jelly contain the following raw material and auxiliary materials, wherein the raw material comprises 1400-1600g of collagen; and the auxiliary materials comprise 3000-3500g of fructo-oligosaccharide, 700-800g of oligoiso-maltitol, 250-350g of white granulated sugar, 15-30g of konjac, 100-200g of sweet orange fruit powder, 10-25g of sucralose, 10-20g of potassium sorbate and 8500-10000g of purified water. The preparation method mainly comprises the following process steps: quality detection of the raw material and the auxiliary materials, sieving, weighing, mixing, solation, volume fixing, filling, sealing, atmospheric sterilization, cooling, forming, packaging andthe like to obtain the finished products; the collagen fruit jelly has good mouthfeel; and the production process is simple and has short time.
Owner:BRAVEIY BIOTECHNOLOGY (ANHUI) CO LTD

ICA angioplasty with cerebral protection

InactiveUS20050149103A1Reduce riskStop blood flowSurgeryDilatorsBlood flowRetrograde Flow
The present invention provides a method and device for preventing cerebral embolization during endovascular procedures in the carotid arteries. The invention comprises a guide catheter and balloon, which may selectively occlude the common carotid artery, and further comprises a wire and balloon, which may selectively occlude the internal carotid artery. Occlusion of the common carotid artery will induce retrograde flow at the site, redirecting emboli to the external carotid artery. Occlusion of the internal carotid artery reduces the risk of emboli migrating to the brain, and allows clearance of the site by antegrade blood flow from the common carotid artery. Occlusion of both the common and internal carotid arteries induces a quiescent state at the site during the procedure. Control of blood flow by selective inflation and deflation of either or both balloons, in concert with the procedures, will reduce the risk of emboli migrating to the brain.
Owner:WL GORE & ASSOC INC

A stent and a stent system

ActiveCN109700581AEnough maneuverable spaceReduce harmStentsInsertion stentDuctus arteriosus
The invention relates to a stent. The stent includes at least one degradable section zone and at least one non-degradable section zone which are connected to each other. The axial length of the at least one degradable section zone is not less than 3 mm. At least one end of the stent is provided with the non-degradable section zone the axial length of which is not less than 3 mm. The stent enablessubsequent arterial duct closing after implantation of the stent into an arterial duct without the need of taking out the stent, thus reducing the probability of harm to child patients and other complications. The invention also provides a stent system.
Owner:BIOTYX MEDICAL (SHENZHEN) CO LTD

Double-pipe and double-channel syringe and needle

InactiveCN105727401AAvoid complications of vascular embolismInjection is effective and safeInfusion syringesInfusion needlesPistonSevere complication
The invention discloses a double-tube double-channel syringe and a needle head, including a needle tube, a needle head is arranged at the front end of the needle tube, a first partition is arranged inside the needle tube along the length direction, and the needle tube is divided into a first cavity and a first cavity by the first partition. In the second cavity, the first cavity is provided with a first piston, the first piston is provided with a first piston handle, the second cavity is provided with a second piston, and the second piston is connected with a second piston handle. The two piston handles are arranged outside the second cavity; along the length direction, the needle is divided into a third cavity and a fourth cavity through the second partition, and the third cavity communicates with the first cavity; the fourth cavity communicate with the second cavity. In the present invention, the separation of the first cavity and the second cavity but the design of the needle entering the same blood vessel realizes the relatively independent injection of hyaluronic acid and blood withdrawal, which effectively avoids the most serious complication of hyaluronic acid injection, vascular embolism, and can be performed effectively and safely. Hyaluronic acid injections allow doctors and patients to perform injections with greater confidence.
Owner:NORTHWEST WOMEN & CHILDREN HOSPITAL

Fat-reducing slimming instant powder

The invention relates to a weight- and blood fat- reducing infusion prepared of pure Chinese medicinal herbs and the preparing process thereof, prepared of fifteen Chinese medicinal herbs such as Virgate Wormwood Herb, Oriental Waterplantain Rhizome, Cassia obtusifolia L, etc, by the following steps of: washing, drying, mixing and crushing->decocting->placing->concentrating->preparing soft material->making granules->drying->regulating granules->split-charging->checking->obtaining the finished products, and it relates pathogenesis of adiposity, high blood fat, diabetes and hihg blood pressure, improving micro circulation, increasing blood flow, improving blood viscosity, preventing cardio and cerebral embolism, anti-oxidizing, eliminating in vivo free radicals, reducing blood fat, clearing pulse, reducing blood pressure and sugar, reducing weight, thus having obvious clinical curative effect on patients with adiposity, high blood fat, diabetes and hihg blood pressure, and able to prevent diseases and senescence and prolong life.
Owner:黄如瑞

Traditional Chinese medicine composition capable of removing acne

The invention provides a traditional Chinese medicine health care composition capable of removing acne, which comprises the following components by weight: 5-7 parts of wild chrysanthemum flower, 3-5 parts of dahurian angelica root, 8-10 parts of honeysuckle flower and 3-7 parts of fructus forsythia. The composition effectively combines several components together, enables synergism, is capable of removing acne, and has the efficacy of treating diseases and preserving health.
Owner:梅广浦

Minimally invasive positioning tool for laparoscopic surgery and protected supporting and positioning method of tool

The invention discloses a minimally invasive positioning tool for a laparoscopic surgery and a protected supporting and positioning method of the tool, and relates to a minimally invasive positioning tool and a minimally invasive surgery method. A pneumoperitoneum operation mode of an existing laparoscopic surgery is very harmful to human bodies and large in wound, surgical difficulty and dangerousness are increased, other pneumoperitoneum modes are very harmful to patients and cause many complications, and standard operation is difficultly realized as an affected part of an abdominal cavity needs to be cut by the aid of experience of a doctor due to a narrow surgical field. A unilateral slide can be connected with a detachable base, a movable base is in sliding fit with the unilateral slide, a supporting component is arranged on the movable base, a buffer type guide head is arranged at one end of an intubation tube, a gas filled bag is arranged inside the intubation tube and communicated with a gas source, and a plurality of slot holes are formed in the intubation tube. The protected supporting and positioning method is characterized in that the gas source is started, gas flow with a gas pressure value P is led into the gas filled bag of the intubation tube, and the gas filled bag is filled with gas to form multi-point supporting or arc-shaped supporting. The minimally invasive positioning tool and the protected supporting and positioning method are used for the laparoscopic surgery.
Owner:JIAMUSI UNIVERSITY

Infusion alarm device capable of automatically prompting when infusion completes

The invention discloses an infusion alarm device capable of automatically prompting when infusion completes. The infusion alarm device comprises an infusion hanging box, and is characterized in that a spring for infusion hanging is fixedly mounted in the infusion hanging box, a metal sheet is connected to the lower end of the spring, one side of the metal sheet extends to form a contact piece, and a capacity position selection switch, namely an infusion alarm switch, which is can be adjusted up and down, is mounted on the side face of the infusion hanging box; a control box is arranged in the infusion hanging box and is connected with the contact piece and the infusion alarm switch through wires, and a power switch, a power light and a buzzer are arranged in the control box. The infusion alarm device capable of automatically prompting when infusion completes has the advantages that the situation that an infusion bottle is empty during infusion can be prevented, or air can be prevented from entering a blood vessel to result in air embolism by timely discovering that the air enters the infusion tube; the infusion alarm device is capable of reducing burden of accompanied personnel or medical personnel.
Owner:SHAANXI EYINHE ELECTRONICS

Rotary continuous venous transfusing device for small animal model

The invention relates to a medical experimental tool, in particular to a rotary continuous venous transfusing device for a small animal model, which is suitable for performing long-term durable and effective venous transfusion on a small medical experimental animal without influencing free movement of the small experimental animal in the medical experimental process. The device is formed by connecting a disposable transfusing apparatus, a heparin cap, a disposable injector needle tube and a disposable injector needle head in series in sequence, and is connected with a silicone tube; one end of a spring protecting sleeve is fixedly connected to the needle head; the needle cap is sleeved into the needle head which is connected with the silicone tube and the spring protecting sleeve; the center of a plastic fixing plate is provided with a recess; the center of the recess is provided with a hole; a hollow rivet is fixedly connected with the other end of the spring protecting sleeve by passing through the central hole of the plastic fixing plate; a triangular gap is cut on the side wall of the needle tube; and standby needle holes are formed on the periphery of the plastic fixing plate.
Owner:杨建军 +1

Valve replacement devices

An embolic material blocking catheter includes a handle assembly, an elongated element having a lumen, and a deployable embolic material blocking element. The embolic material blocking catheter is configured to accommodate insertion of a treatment catheter into the lumen to position a treatment device distal to the embolic material blocking element for administering a treatment at a treatment site and / or convey embolic material blocked by the embolic material blocking element for extraction from the patient.
Owner:EMSTOP INC

Dilator assembly

The invention relates to a dilator assembly which comprises a dilator, a dilation catheter, a sheath, a hemostasis valve, a push rod shell and a push rod. The dilation catheter is fixed at the far end of the sheath, the near end of the sheath is connected with the hemostasis valve, and the dilator can freely slide in the sheath; the dilator is jointly composed of a hollow tubular inner dilator and a tubular outer dilator arranged outside the inner dilator, the outer dilator is connected with the inner dilator in a closed mode at the tail end of the far end, an annular gap exists between the outer dilator and the inner dilator, and the annular gap is used for at least partially containing an dilation catheter. The guide-in process of the dilation catheter is safer and more effective; the locking structure is arranged at the near end of the dilator, a leading-in sheath and the dilator can be locked before the dilator enters the human body, and the dilator is prevented from sliding back and forth after the dilator enters the human body to damage the blood vessel wall or other coelomic membranes.
Owner:上海玮琅医疗科技有限公司

Nano fibrous tissue engineering blood vessel and preparation thereof

The invention relates to a tissue engineering material and a preparation method thereof, in particular to a nano fiber tissue engineering blood vessel and a preparation method thereof. The invention consists of a three-dimensional reticular non-woven film formed by an inner layer of nano fiber and an outer layer of nano fiber; the inner layer of the blood vessel is natural polymer, wherein, calculated by weight, 40 percent to 80 percent is fibroin, 20 percent to 50 percent is gelatine, 0 percent to 20 percent is extracellular matrix protein; while the outer layer of the blood vessel is synthetic polymer. The preparation method is that the natural polymer is dissolved in trifluroroethyl and other solution, while the synthetic polymer is dissolved in hexafluoroisopropanol and other solution, which are respectively prepared into spinning solution; the static electricity spinning technique is adopted to subsequently form the inner and the outer layers on a gather roller; cross-linked treatment is conducted after the inner and the outer layers are taken down, to prepare the nano fiber tissue engineering vessel. The inner layer can simulate the structure of the extracellular matrix, provide good environment for endothelial cells to grow, support adhesion, proliferation and differentiation of the cells, and is good for endothelization of the blood vessel; and the outer layer has goodmechanical performance.
Owner:SUZHOU UNIV

Preparation process of dalteparin sodium

The invention discloses a preparation process of dalteparin sodium. The preparation process comprises the following steps: preparing a heparin sodium solution, a heparin degradation fluid, a reducing solution and a crude product, refining, freeze-drying and the like. The average molecular weight of the obtained product is 5,500 to 6,500, the peak molecular weight is 3,500 to 6,000, a component with the molecular weight of less than 3,000 is not greater than 13% , a component with the molecular weight of greater than 8,000 is not greater than 15%, anti-Xa activity is more than or equal to 130IU / mg. The invention has the advantages of rich source of raw materials, high yield, stable and reliable quality, high purity, low cost, simple process, easiness in operation and no waste discharge. The dalteparin sodium has the anticoagulant, antithrombotic, anti-tumor, anti-inflammatory, anti-allergy and blood lipid regulating effects, thereby having a significant curative effect. The dalteparin sodium can be used for preventing preoperative and postoperative thrombosis of general surgery, orthopedic surgery and neurosurgery, effectively preventing venous thromboembolism of ischemic stroke patients, greatly reducing the risk of stroke, effectively preventing the solidification caused by extracorporeal circulation of blood, effectively preventing the instable coronary heart disease, and having a wide usable range.
Owner:HEBEI CHANGSHAN BIOCHEM PHARMA

Experimental method for preventing generation and growth of liver cancer by using umbilical cord mesenchymal stem cells

The invention relates to an experimental method for preventing generation and growth of liver cancer by using umbilical cord mesenchymal stem cells. For the first time, an application of the umbilicalcord mesenchymal stem cells to prevent the generation and growth of liver cancer is provided. The UC-MSCs cell preparation method is provided, and the experimental data of the dose of 1*104 cells / treatment course and administration method of the UC-MSCs cells for preventing liver cancer are provided. A UC-MSCs preparation is transplanted firstly, then the liver cancer cells are implanted, and thetumor growth of NOD / SCID mice is observed and compared, the method proves that the umbilical cord mesenchymal stem cells can prevent the generation and development of liver cancer and the dosage of UC-MSCs is provided, the self-renewal and damage repair functions of UC-MSCs in the body's adult organ tissue can be maximized, the body's immunity is improved, and the generation of liver cancer can be prevented, which is beneficial to play a more significant and stable role in later research and clinical applications.
Owner:TIANJIN KANGTING BIOLOGICAL ENG GRP CO LTD
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