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Walnut oil fat emulsion and manufacturing method thereof

A fat emulsion, walnut oil technology, applied in the direction of antitoxin, pharmaceutical formula, emulsion delivery, etc., can solve the problems such as research reports and patents of walnut oil that have not yet been seen

Inactive Publication Date: 2008-04-30
陈朝银
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But up to now, do not see the research report and the patent that walnut oil is used as fat emulsion as yet

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Formula: pure walnut oil 100g / l, refined lecithin 11g / l, anhydrous glycerin 22g / l, appropriate amount of sodium hydroxide, the rest is pure water without pyrogen.

[0025] 1. Preparation of water phase solution: add glycerin to pyrogen-free pure water in a steam jacketed pot, stir and dissolve to form a water phase;

[0026] 2. Preparation of oil phase solution: In a steam jacketed pot, heat the refined walnut oil to 70°C, stir and add refined lecithin until it dissolves to form an oil phase;

[0027] 3. Primary milk preparation: slowly add the oil phase to the strongly stirred water phase and continue to vigorously stir for 10 minutes to form primary milk;

[0028] 4. Adjust the pH of the primary milk to 7.2 with a small amount of sodium hydroxide solution;

[0029] 5. Use a high-pressure homogenizer to homogenize the primary milk repeatedly, and adjust the homogenization pressure to 600kg / cm in the first stage 2 Homogenize 1-2 times, the homogenization pressure of the sec...

Embodiment 2

[0032] Formula: 200g / l of refined walnut oil, 12g / l of refined lecithin, 18g / l of anhydrous glycerin, appropriate amount of sodium hydroxide, and the rest is pure water without pyrogen.

[0033] 1. Preparation of water phase solution: add glycerin to pyrogen-free pure water in a steam jacketed pot, stir and dissolve to form a water phase;

[0034] 2. Preparation of oil phase solution: In a steam jacketed pot, heat the refined walnut oil to 80°C, stir and add refined lecithin until it dissolves to form an oil phase;

[0035]3. Primary milk preparation: slowly add the oil phase to the strongly stirred water phase and continue to vigorously stir for 10 minutes to form primary milk;

[0036] 4. Adjust the pH: adjust the pH of the primary milk to 8 with a small amount of sodium hydroxide solution;

[0037] 5. Homogenization: Use a high-pressure homogenizer to homogenize the primary milk repeatedly, and adjust the homogenization pressure to 590kg / cm in the first stage 2 Homogenizing for...

Embodiment 3

[0041] Formula: pure walnut oil 300 g / l, refined lecithin 13 g / l, anhydrous glycerin 16 g / l, appropriate amount of sodium hydroxide, and the rest is pure water without pyrogen.

[0042] 1. Preparation of water phase solution: add glycerin to pyrogen-free pure water in a steam jacketed pot, stir and dissolve to form a water phase;

[0043] 2. Preparation of oil phase solution: In a steam jacketed pot, heat the refined walnut oil to 90°C, stir and add refined lecithin until it dissolves to form an oil phase;

[0044] 3. Primary milk preparation: slowly add the oil phase to the strongly stirred water phase and continue to vigorously stir for 10 minutes to form primary milk;

[0045] 4. Adjust the pH: adjust the pH of the primary milk to 8.5 with a small amount of sodium hydroxide solution;

[0046] 5. Homogenization: homogenize the primary milk with a high-pressure homogenizer, first adjust the pressure to 590kg / cm 2 Homogenize for 1 to 3 times, then adjust the pressure to 150kg / cm 2...

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PUM

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Abstract

The invention relates to walnut oil intralipid and process for preparation, belonging to the technical field of food and drug. The formulation comprises pure walnut oil, refining lecithin, pure glycerin, caustic soda and pyrogen-free pure water. The basic preparing procedures are as follows: pure walnut oil, refining lecithin, glycerin and water are vigorously stirred into primary milk and the pH value of the primary milk is adjusted to 7.5-8.5 through little caustic soda solution, and then high-pressured and homogenized, filtered by a filter, bottled, sealed and sterilized. The walnut oil intralipid is an artificial chyle product which is prepared by simulating natural chyle granules existing in blood and can be intravenously injected as 'parenteral nutrient solution' to rescue lives of some severe patients, (such as severely burned patients, traffic accident injured patients, patients with great operations, patients with advanced tumor and cachexia, etc.) and furthermore can be used for complementarily curing some dystrophic diseases and also can be orally taken as nutrition supplementary and auxiliary treatment. The invention can increase essential energy for body metabolism, provide biological film for body and essential 'polyunsaturated fatty acid' for biologically active substance metabolism, and prevent and correct deficiency of essential fatty acid for body. The invention has a plurality of therapeutic functions of blood sugar reduction, anti-oxidative damage, anti-anaphylaxis, anti-cell senescence, and anti-cardiovascular hardness and the like, and provides a new direct and convenient way through which edible and medical walnut effective component can enter human body.

Description

Technical field [0001] The invention relates to a walnut oil fat emulsion and a manufacturing method thereof. The walnut oil fat emulsion can increase the energy necessary for the body's metabolism, and can provide the body with "polyunsaturated fatty acids" required for the metabolism of biofilms and biologically active substances to prevent And to correct the lack of essential fatty acids in the body, and have a variety of therapeutic effects such as lowering blood fat, lowering blood sugar, anti-oxidation damage, anti-allergic, anti-cell aging, and anti-cardiovascular sclerosis. It is suitable for intravenous injection or oral administration. It belongs to medicine and food technology. field. Background technique [0002] The concept of fat emulsion began in the 1960s. At that time, in order to rescue the lives of some critically ill patients (such as severe burn patients, traffic accidents injured, undergoing major surgery, patients with advanced tumors and cachexia, etc.) "I...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/52A61K9/107A61P3/02A61P3/06A61P3/10A61P9/10A61P37/08A61P39/06A61K131/00
Inventor 陈朝银赵声兰
Owner 陈朝银
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