44 results about "PN - Parenteral nutrition" patented technology

Bioavailable iron-containing parenteral nutrition compositions are provided that are physico-chemically stable. Iron is present in the form of soluble ferric pyrophosphate. Methods of preparation and use of the compositions are provide, as well as kits.

The invention relates to a stable compound containing a plurality of vitamins and the method for preparing same. The compound comprises at least four kinds of fat-soluble vitamin, cholate, phosphatide and carriers or findings acceptable by pharmacy. The compound also comprises water soluble vitamins. The compound is a clear and transparent solution. The preparing method comprises: (1) dissolving the fat-soluble vitamin with liquid containing ethanol; (2) removing ethanol. The compound is used as nutriment for patients.

The present invention relates to structured triglyceride, to parental nutrition emulsions comprising same, and use thereof. In particular, the invention relates to structured triglycerides comprising at least one medium chain C6-C12 fatty acid and at least one fatty acid selected from the group consisting of long chain C14-C18 or very long chain C20-C22 fatty acids, preferably each fatty acid is present in a predetermined position of the glycerol backbone. The parenteral nutrition emulsions are particularly useful for nourishing preterm-and term-infants, children, critically ill patients, and cancer patients.

The invention belongs to a parenteral nutrition infusion pump, an extrusion device which respectively extrudes three infusion tubes is arranged in a housing, a fixing slot for fixing the three infusion tubes is arranged in the housing, a bubble detector, a pressure detector and a liquid stopping clip are arranged on the housing at the output end of the infusion tubes, a left housing cover and a right housing cover which are opened to two sides are arranged at the upper end of the housing, and a liquid crystal display screen and a control keyboard are arranged on one housing cover. The parenteral nutrition infusion pump can rapidly and safely complete the three-channel infusion process and have the advantages of simple structure, time-saving and effort-saving properties, safety, sanitation, convenient use and good effect.

The present invention is one kind of three-cavity packed injection composition, and has medium / long chain fatty milk injection, compound amino acid injection and glucose injection packed separately in three diaphragm separated cavities. Before intravenous infusion, the medium / long chain fatty milk injection, the compound amino acid injection and the glucose injection are squeezed out and mixed in common operation condition. The injection composition can be used to patient for meeting the requirement in protein and saccharide.

The invention relates to walnut oil intralipid and process for preparation, belonging to the technical field of food and drug. The formulation comprises pure walnut oil, refining lecithin, pure glycerin, caustic soda and pyrogen-free pure water. The basic preparing procedures are as follows: pure walnut oil, refining lecithin, glycerin and water are vigorously stirred into primary milk and the pH value of the primary milk is adjusted to 7.5-8.5 through little caustic soda solution, and then high-pressured and homogenized, filtered by a filter, bottled, sealed and sterilized. The walnut oil intralipid is an artificial chyle product which is prepared by simulating natural chyle granules existing in blood and can be intravenously injected as 'parenteral nutrient solution' to rescue lives of some severe patients, (such as severely burned patients, traffic accident injured patients, patients with great operations, patients with advanced tumor and cachexia, etc.) and furthermore can be used for complementarily curing some dystrophic diseases and also can be orally taken as nutrition supplementary and auxiliary treatment. The invention can increase essential energy for body metabolism, provide biological film for body and essential 'polyunsaturated fatty acid' for biologically active substance metabolism, and prevent and correct deficiency of essential fatty acid for body. The invention has a plurality of therapeutic functions of blood sugar reduction, anti-oxidative damage, anti-anaphylaxis, anti-cell senescence, and anti-cardiovascular hardness and the like, and provides a new direct and convenient way through which edible and medical walnut effective component can enter human body.

The invention relates to a venous transfusion drug dispensing center, and belongs to a medical facility in a hospital. According to the technical scheme, the venous transfusion drug dispensing centercomprises a cleaning area, an auxiliary working area and a living area; the cleaning area comprises a dispensing room which is separated from each other and sealed in space, and the dispensing room isdivided into a dispensing room of antibacterial and hazardous drugs and a dispensing room of ordinary drugs and parenteral nutrition; the auxiliary working area is further provided with a matched finished-product transfusion review area, a drug and material storage room, a verification party printing room, a dispensing preparation room, a finished-product verification room, a packaging room and ageneral dressing functional room, and isolation facilities need to be arranged in areas with different cleanliness levels to prevent cross contamination. According to the venous transfusion drug dispensing center, a biosafety operating platform required by negative pressure and conventional transfusion dispensing are uniformly arranged in the venous transfusion dispensing center, the quality of afinished transfusion is ensured, the occupational injury is reduced, the air conditioning division management of the conventional dispensing environment and negative pressure dispensing environment is adopted, and the leakage of a toxic and harmful chemical drug preparation is avoided.

A parenteral nutritional diagnostic system, apparatus, and method are disclosed. In an example embodiment, a parenteral nutritional diagnostic apparatus determines muscle quantity and muscle quality of a patient's psoas muscle to determine a nutritional status of the patient. An image interface is configured to receive a medical image including radiodensity data related to imaged tissue of the patient. The apparatus also includes a processor configured to use the medical image to determine a tissue surface area for each different value of radiodensity and determine a distribution of the tissuesurface area for each radiodensity value. The processor is configured to determine muscle quality by locating a soft tissue peak within the distribution that corresponds to a local peak in at a region related to at least one of muscle tissue, organ tissue, and intramuscular adipose tissue. The processor determines the nutritional status of the patient based on soft tissue peak.

The invention relates to a high-amino-acid, low-lipid and low-carbohydrate parenteral nutrition solution for administration to obese intensive-care patients, and to a three-chamber pouch which comprises the amino acid component, the carbohydrate component and the lipid component of the parenteral nutrition solution separately in three different chambers.

The present disclosure relates to a sterile medical product for parenteral nutrition comprising a polymeric container having at least a first and a second chamber which are separated by a non-permanent peel seal, wherein the first chamber contains a composition of amino acids and optionally electrolytes, and wherein the second chamber contains a dextrose solution, and wherein the product is characterized by a high protein (nitrogen) content per volume. The reconstituted solution is configured to be administered peripherally or centrally for the treatment of patients suffering from malnutrition and / or having a need for increased uptake of amino acids.

The invention belongs to the technical field of nutrient solution preparation, and particularly relates to a parenteral nutrient solution preparation device and a preparation method thereof. The device comprises an outer cylinder and an injection module, the injection module is clamped to the top of the outer cylinder, and a second protective cover is fixedly connected to the outer side of the outer cylinder; in the present invention, a first fan-shaped cavity, a second fan-shaped cavity and a third fan-shaped cavity are formed in the top of a mixing module; different kinds of liquid are respectively injected into the three fan-shaped cavities through the injection pipes; then, the mixed liquid is introduced into the mixing module to be stirred; the relative positions of a first-stage mixing cylinder, a second-stage mixing cylinder, a third-stage mixing cylinder and a fourth-stage mixing cylinder are adjusted through the output end of an electric push rod, the mixing uniformity degreeof nutrient solutions in the mixing module can be improved, redundant air in the mixing module can be exhausted according to the preparation amount of the nutrient solutions, the probability that impurities in the air pollute the nutrient solutions is reduced, and the preparation quality of the nutrient solutions is improved.

The invention discloses a total parenteral nutrient solution preparation device, and relates to the technical field of parenteral nutrient solution preparation. The device comprises a quantifying mechanism, a preparing mechanism, a stirring mechanism, a fixing mechanism and a shaking-up mechanism. The bolt is fixedly arranged on the inner surface of the clamping groove and penetrates through the inserting groove, and the outer surface of the threaded shaft is in threaded connection with the end cover, wherein the threaded shaft is rotatably arranged above the piston, the driving wheel is arranged on the outer surface of the sleeve shaft, the elastic piece is arranged on the outer surface of the pressing plate, and the transmission block is arranged at one end of the transmission rod. By arranging the quantifying mechanism, the preparing mechanism, the stirring mechanism, the fixing mechanism and the shaking-up mechanism, medicine can be conveniently and quantitatively injected, the medicine can be conveniently injected, stirring and uniform mixing are convenient, a nutrition bag can be conveniently fixed, a nutrient solution can be automatically shaken up, and the labor intensity of workers is reduced. Therefore, preparation operation of the nutrient solution is greatly facilitated, the preparation efficiency can be improved to a certain extent, and the device is suitable for large-scale preparation.

GLP-2 analogs, such as teduglutide, and fusion proteins of GLP-2 with immunoglobulin are administered before, during or after surgery, particularly resection of the small intestine. When short bowel syndrome develops after surgical resection of the small intestine, parenteral nutrition is usually necessary to compensate for reduced absorption of water and nutrients across the small intestine. GLP-2 analogs and GLP-2 fusion proteins promote growth of small intestine, improve nutrient absorption and can reduce the need for parenteral nutrition after surgery.

The invention relates to a prescription information pushing method and device based on parenteral nutrition and computer equipment. The method comprises the following steps: acquiring a parenteral nutrition prescription pushing task, wherein the parenteral nutrition prescription pushing task carries a patient identifier; acquiring patient information corresponding to the patient identifier, and determining a corresponding energy factor according to the patient information; calling an index matching model, wherein the index matching model is established by performing big data analysis based onhistorical patient information and historical prescription information; matching the patient information according to the index matching model to obtain reference quantities corresponding to a plurality of nutrition index items; determining a target amount corresponding to the nutrition index item based on the energy factor and the reference amount; and generating prescription information according to the target quantity, and pushing the prescription information to a corresponding terminal. By adopting the method, the time cost for determining the prescription information based on parenteral nutrition can be saved, and the workload of doctors is reduced.

The invention belongs to the application of a computer technology in a clinical technology, and particularly relates to the field of parenteral nutrition intervention, more particularly to an intelligent parenteral nutrition physician order system. The intelligent parenteral nutrition physician order system comprises a data docking module, an automatic prescription generation module and a prescription auditing control module. After a technical scheme disclosed by the invention is adopted, a parenteral nutrition prescription can be automatically generated without manually inputting information,so the processes of manual inputting, manual calculation and the like are avoided, and the safety, effectiveness and reasonability of the parenteral nutrition prescription are ensured. Meanwhile, dueto the fact that automatic monitoring can be achieved, the problems of hysteresis quality and the like of manual monitoring are avoided, and the safety and effectiveness of the parenteral nutrition prescription can be further improved. In addition, the technical scheme provided by the invention can effectively promote automated development of parenteral nutrition.

The invention relates to a high-amino-acid, low-lipid and low-carbohydrate parenteral nutrition solution for administration to obese intensive-care patients, and to a three-chamber pouch which comprises the amino acid component, the carbohydrate component and the lipid component of the parenteral nutrition solution separately in three different chambers.

The present disclosure relates to parenteral nutrition formulations, including ready-to-use parenteral nutrition formulations which are reconstituted from multi-chamber containers and amino acid formulations. More particularly, the present disclosure is directed to formulations comprising butyrate derivatives, specifically arginine butyrate, for use with adult or pediatric patients. The disclosure further provides for methods of reducing or preventing systemic and local inflammation of patients receiving parenteral nutrition, and methods of maintaining or ameliorating their systemic immunity and local immunity, as well as the patients' gut barrier functions.

GLP-2 analogs, such as teduglutide, and fusion proteins of GLP-2 with immunoglobulin are administered before, during or after surgery, particularly resection of the small intestine. When short bowel syndrome develops after surgical resection of the small intestine, parenteral nutrition is usually necessary to compensate for reduced absorption of water and nutrients across the small intestine. GLP-2 analogs and GLP-2 fusion proteins promote growth of small intestine, improve nutrient absorption and can reduce the need for parenteral nutrition after surgery.

The invention discloses a high-efficiency intelligent medicine and parenteral nutrition product automatic checking and returning function machine, which includes a feeding conveyor belt, an outgoing conveyor belt, a returning conveyor belt and a control computer; the intersection of the feeding conveyor belt, the outgoing conveyor belt and the returning conveyor belt Set up the detection module. In the present invention, the dispensing of the medicine is arranged in the form of an assembly line, the weighing and comparison of the medicine is carried out by setting a measuring scale on the tooth plate, and four cameras with different angles are used for auxiliary identification, so as to automatically detect the accuracy of dispensing the medicine. Wrong medicine can also be checked by returning to the original position by returning to the conveyor belt, which greatly improves the efficiency and accuracy of dispensing medicine and reduces labor costs.

The invention relates to the technical field of gastrointestinal cancer cell postoperative monitoring, in particular to gastrointestinal cancer cell postoperative rehabilitation monitoring equipment based on monolithic medical association.The gastrointestinal cancer cell postoperative rehabilitation monitoring equipment comprises an information monitoring module, a medical analysis module, a review planning module and a doctor's advice nursing module; the monitor is used for monitoring frequency spectrum information of gastrointestinal cancer cells, the medical analysis module comprises a correlated medical library and a monitoring analysis unit, and the monitoring analysis unit is used for analyzing and processing the frequency spectrum information according to logic rules of the correlated medical library to generate corresponding monitoring result information. The gastrointestinal cancer cell postoperative rehabilitation state is accurately monitored and analyzed, corresponding review plan information, medical advice application antibacterial drug information and parenteral nutrition nursing information can be pushed according to the monitoring result information, the auxiliary guiding effect is achieved for gastrointestinal cancer cell postoperative rehabilitation medical care, and the gastrointestinal cancer cell postoperative rehabilitation state can be accurately monitored and analyzed. The monitoring effect of the postoperative rehabilitation state of gastrointestinal cancer cells is improved.

The present disclosure relates to a sterile medical product for parenteral nutrition comprising a polymeric container having at least a first and a second chamber which are separated by a non-permanent peel seal, wherein the first chamber contains a composition of amino acids and optionally electrolytes, and wherein the second chamber contains a dextrose solution, and wherein the product is characterized by a high protein (nitrogen) content per volume. The reconstituted solution is configured to be administered peripherally or centrally for the treatment of patients suffering from malnutrition and / or having a need for increased uptake of amino acids.

A composition for use in the treatment of a patient suffering from or being at risk of developing a gastrointestinal disorder is disclosed. The composition is an aqueous solution for injection comprising arginine butyrate in a concentration of from 150 mg / L to 5500 mg / L of the composition. A method of treating a patient suffering from or being at risk of developing a gastrointestinal disorder by administering the related compositions is also disclosed.

Container for a mixing system being filled with liquid parenteral nutrition and comprising a male connector and a female connector is disclosed. The male connector is placed on the opposite side of the container compared to the female connector and the male connector and the female connector are embodied to be mechanically engageable with each other and to engage a mechanical connection with a male connector or a female connector respectively of another container and to form a channel, which enables the passage of liquid. At least two containers form a modular system for parenteral nutrition.

The invention relates to non-systemic TGR5 agonist useful in the treatment of chemotherapy-induced diarrhea, diabetes, Type II diabetes, gestational diabetes, impaired fasting glucose, impaired glucose tolerance, insulin resistance, hyperglycemia, obesity, metabolic syndrome, ulcerative colitis, Crohn's disease, disorders associated with parenteral nutrition especially during short bowel syndrome, and irritable bowel syndrome (IBS), and other TGR5 associated diseases and disorders, having the Formula:where R1, R2, R2′, R3, R4, X1, X2, X3, X4, Q, and n are described herein.

There is a need to increase protein synthesis in subjects receiving parenteral nutrition. The present disclosure provides oxidized glutathione (GSSG) or a GSSG analog as a supplement for parenteral nutrition to maintain, promote or increase protein synthesis in a subject receiving parenteral nutrition. The present disclosure also provides a parenteral nutrition solution as well as therapeutic uses of the parenteral nutrition supplement or the parenteral nutrition solution.