36results about How to "Reduce wet weight" patented technology

The invention relates to a pharmaceutical compound and a preparation method and a preparation thereof, in particular to a pharmaceutical compound for curing prostatitis and prostate hyperplasia and a preparation method and a preparation thereof. The pharmaceutical compound is prepared by the following traditional Chinese medicine raw materials according to the parts by weight: 60-100 parts of wuling powder, 20-80 parts of zedoary, 20-80 parts of fritillaria thunbergii and 20-40 parts of alisma orientale. The invention also discloses the preparation method and the preparation of the pharmaceutical compound. The pharmaceutical compound and the preparation thereof have good curative effects to prostatitis and prostate hyperplasia without side effects.

The invention relates to a disease preventing and curing medicinal mouth-muffle and a medicinal composite. The disease preventing and curing medicinal mouth-muffle (1) comprises a mouth-muffle body (2), one surface of the mouth-muffle body (2) is provided with an insert pocket (3), and a powder bag (4) which packages the medicinal composite is placed in the insert pocket (3). The medicinal composite comprises the following Chinese herbs by weight: 2.2 percent of chrysanthemum and muskiness, 4.2 percent of cinnamon, good ginger, long pepper, radix aconite, frankincense, myrrh and clove, 5.0 percent of vermilion, 6.4 percent of asarum, eaglewood, croton, resina draconis, early plum flowers and rhizoma ligustici wallichii and 7.6 percent of tooth soap, arsenic sulphide and brain sand. The disease preventing and curing medicinal mouth-muffle internally carries the medicinal composite which plays a role during the mouth-muffle wearing process, thereby having disease prevention and cure and being simple and direct and also effective in treatment.

The invention relates the use of codonopsis pilosula and astragalus root composition in treating ischemic heart diseases, wherein the composition has functions for treating myocardial ischemia, myocardiac infarction, myocardiopathy, and for treating thrombogenesis, lowering blood viscosity, and reducing platelet aggregation.

The invention relates to a medicinal preparation for treating benign prostate hyperplasia and process for its preparation, wherein the medicament is prepared from astragalus root, peach kernels, zedoary, rhubarb horsetails, poria cocos, coix seed, motherwort, selfheal, Cinnamomum cassia, root of ballon flower, subprostrate sophora root, achyranthes and cyathula root, and medicinal auxiliary materials.

The invention relates to a gallbladder wood leaf composition containing strictosamide. The gallbladder wood leaf composition is characterized in that the gallbladder wood leaf composition is prepared by combining alkaloid and flavonoid extracted from gallbladder wood leaf; the alkaloid contains strictosamide,10-hydroxy-strictosamide and short snakeroot glucoside; the flavonoid contains kaempferol-3-O-rutinoside and rutin; and the total weight of the three alkaloid and flavonoid is 50-98% of that of the composition, and the ratio of the total weight of the three alkaloid and the total weight of the flavonoid is (10-0.7):(0.5-10). The invention also discloses a preparation of the composition. The composition provided by the invention can play the role of clearing away heat and toxic materials and relieving swelling and pain, and can treat diseases such as acute tonsillitis, acute pharyngitis, acute conjunctivitis, upper respiratory tract infection or chronic pelvic inflammatory disease and appendagitis; and can cure slight and medium pain.

The invention discloses 3D flame-retardant fabric and a heat protection garment thereof. The fabric comprises a single-layer portion and a double-layer portion which are in parallel and alternate arrangement. The fabric is made of high-performance flame-retardant yarns and flame-retardant elastic covering yarns, and is formed through interweaving of the yarns by a weaving or warp knitting technology according to a weave diagram. The double-layer portion comprises a surface layer and an inner layer which are completely separated from each other. The inner layer is made of the high-performance flame-retardant yarns and the flame-retardant elastic covering yarns. The surface layer is made of the high-performance flame-retardant yarns. Through arraying of connection joints of the single-layerportion and the double-layer portion under the action of the flame-retardant elastic covering yarns, the surface layer and the inner layer are different in stress rebound resilience of raw materials,and are separated from each other, so that a 3D air cavity protrusion structure is formed at the separation position. The heat protection garment comprises the 3D flame-retardant fabric, or comprisesa heat-insulating comfort layer, a waterproof breathable layer and a flame-retardant outer layer from inside to outside sequentially. The heat-insulating comfort layer, the waterproof breathable layerand the flame-retardant outer layer are made of the 3D flame-retardant fabric.

The invention discloses Chuzhou chrysanthemum general flavone grains, which are formed by the following raw materials in weight ratio of sucrose powder to dextrin to dry Chuzhou chrysanthemum general flavone extract powder of (0.5-1.5): (1.5-2.5): (0.5-1.5). The Chuzhou chrysanthemum general flavone is prepared into a granular formulation and the granular formulation has the good molding performance; the performance, the granularity, the water, the dissolubility and the like meet the requirements; the quality is controllable and the stability is good; commodity chrysanthemums are prevented from color change and smell loss in a storing process; the content of effective components is not reduced; and a phenomenon that the color of separated parts in an immersing process becomes green is avoided. The Chuzhou chrysanthemum general flavone grains can obviously delay blood caking time of rats with blood stasis due to cold accumulation, reduce the length, and dry and wet weights of in-vitro thrombus, reduce deposition of red blood cells, decrease red blood cell settling speed and raise the NO content of blood serum. The product has the characteristics of convenience for carrying and drinking, easiness for storing, no toxic or side effect, capabilities of preventing, treating and improving abnormal conditions of hemorheology of the rats with the blood stasis, and the like.

The invention discloses a synthetic method of a ferulic acid derivative, which comprises the steps of adding 10-20 g of ferulic acid ethyl ester and 30-100 ml of tetrahydrofuran into a reaction vessel; stirring to completely dissolve the ferulic acid ethyl ester in the tetrahydrofuran; adding 8-20 g of anhydrous sodium carbonate in the above mixture; adding 5-15 g of acetic anhydride in a hopper; slowly adding acetic anhydride in a normal-temperature water bath; stirring and heating the mixture at 30-55 DEG for 5 to 2 hours; adding 30-100 ml of purified water; stirring the mixture and collecting the organic horizon; leaching and drying the solid compound to obtain acetyl ferulic acid ethyl ester as shown in the formula (I), wherein R1 and R2 are respectively C1-10 alkyl. According to the compound as shown in the formula (I), ferulic acid molecule is used as the base. By modification or reconstruction of the side-chain structure of the ferulic acid molecule, stability of ferulic acid is raised, and its pharmacological effects are substantially enhanced.

GLP-2 analogs, such as teduglutide, and fusion proteins of GLP-2 with immunoglobulin are administered before, during or after surgery, particularly resection of the small intestine. When short bowel syndrome develops after surgical resection of the small intestine, parenteral nutrition is usually necessary to compensate for reduced absorption of water and nutrients across the small intestine. GLP-2 analogs and GLP-2 fusion proteins promote growth of small intestine, improve nutrient absorption and can reduce the need for parenteral nutrition after surgery.

The invention relates to a solar cell with three gate electrode structures. A front face gate line structure comprises three symmetrical primary gate lines and a plurality of evenly distributed secondary gate lines perpendicular to the primary gate lines, one primary gate line is located on the center line of a silicon wafer, and the two ends of each primary gate line and the part, connected with the corresponding primary gate line, of each secondary gate line are respectively of a gradual change type structure. A back face structure comprises three primary gate lines corresponding to the front face gate lines, and asymmetric direction signs smaller than the width of the gate lines exist in the grate line direction. According to the gradual change type structures of the two ends of the primary gate lines, the two ends of each primary gate line gradually narrow down and are of a trapezoid gradual change stricture. According to the gradual change stricture of each secondary gate line, in the junction of the secondary gate line and the corresponding primary gate line, the width of the position, close to the corresponding primary gate line, of the secondary gate line is large, the secondary gate line gradually narrows down when far away from the corresponding primary gate line, and when the secondary gate line reaches a certain length, the width of the secondary gate line is the smallest and will no longer change. The solar cell with the three gate electrode structures can lower cell cost, improve the efficiency of solving problems, and improve the efficiency of a battery piece to a certain extent.

The invention relates to Qishenmai, a traditional Chinese preparation for treating coronary disease and angina pectoris and process for preparation, and provides a Qishenmai injection, wherein the preparation process includes, merging ophiopogon root, pseudo-ginseng, root of American ginseng or American ginseng leaves proportionally, or extracting by boiling with water respectively, removing impurities through ethanol deposition, refining with big hole resin columns, purging with ethanol again, collecting the eluent, filtering, thus preparing pharmacologically acceptable freeze dried, tablet, granule, drop pill, electuary, fluid preparation, powder injection, pill, capsule and suspending agent, or solid dosage forms such as spray and aerosol suitable for local administration.

The invention provides a medicinal liquor for alleviating clinical symptoms of reddening and swelling and heat pain. The medicinal liquor has a formula containing 400-600 parts by weight of alcohol and the following medicinal materials immersed in the alcohol in parts by weight: 2-4 parts of rheum officinale, 2-4 parts of scutellaria baicalensis, 2-4 parts of phellodendron, 2-4 parts of coptis, 2-4 parts of garden burnet, 2-4 parts of white peony root, 4-6 parts of salvia miltiorrhiza and 4-6 parts of safflower. The medicinal liquor for alleviating the clinical symptoms of reddening and swelling and heat pain has substantial treatment effect, simple material selection and no toxic and side effects during clinical use.

The invention discloses a composition for inhibiting benign prostatic hyperplasia, which belongs to the field of healthy food. The composition comprises the following components: mixed tocopherol, lycopene, phytosterol ester and turmeric. The content of curcumin in the turmeric is 40 to 60 percent. The turmeric, lycopene, mixed tocopherol and phytosterol ester are compounded, through the synergistic effect of the components, benign prostatic hyperplasia can be effectively inhibited, and the effect is better than that of single use. In addition, the composition for inhibiting benign prostatic hyperplasia is high in safety and free of toxic and side effects. The invention further provides a preparation method of the composition for inhibiting benign prostatic hyperplasia, and the preparation method is simple in preparation process and can be used for industrial mass production. The invention also provides application of the composition for inhibiting benign prostatic hyperplasia in preparation of a product healthy food for inhibiting benign prostatic hyperplasia.

The invention discloses a novel application of an alchornea trewioides extract in the pharmacy field, and in particular, an application of an alchornea trewioides extract in preparing drugs for treating nonbacterial prostatitis; and an application of an alchornea trewioides extract in preparing drugs for treating nonbacterial prostatic hyperplasia; In addition, the invention also discloses a drug composition for treating nonbacterial prostatitis and prostatic hyperplasia with the alchornea trewioides extract as an active component. Through experiment, the applicant finds that the alchornea trewioides extract can significantly decrease the prostate wet weight and the prostate index of a model animal, has a good inhibition effect on prostate glandular swelling of a nonbacterial prostatitis model rat, can improve blood circulation and promote the softening of the prostate glandular texture, and can mitigate interstitial hyperemia, edema, inflammatory cell infiltration and cell degeneration of prostate cells. Compared with existing and common western medicine, the alchornea trewioides extract has comparable or even better efficacy and less toxicity, and is safer for medication.

The invention relates to the technical field of medicine research and development, in particular to application of a flavone derivative in preparation of a medicine for preventing or treating acute lung injury and / or acute respiratory distress syndrome, the flavone derivative has a structure shown as a formula I, R1 is selected from one of H, C1-C8 alkyl and C3-C10 cycloalkyl, R2 is selected from one of C1-C8 alkyl and C3-C10 cycloalkyl, and R3 is selected from one of C1-C8 alkyl and C3-C10 cycloalkyl. And R2 is selected from aryl groups of C5-C20 or substituted aryl groups of C5-C20. The flavone derivative provided by the invention can obviously inhibit inflammatory response, inhibit release of inflammatory factors, reduce the content of inflammatory factors in alveolar lavage fluid and serum, obviously inhibit pulmonary edema, reduce generation of pulmonary effusion, reduce lung wet weight and inhibit the rising degree of the ratio of the lung wet weight to the lung dry weight caused by acute lung injury; therefore, the effects of resisting inflammation and inhibiting lung edema are achieved.

The invention relates to a medicine for treating benign prostatic hyperplasia and a preparation method thereof. Composed of pharmaceutical excipients. The preparation method is to crush cinnamon, rhubarb, coix seed, and peach kernel into fine powder; extract volatile oil from curcuma decoction pieces; Decoction pieces, zedoary dregs, water-extracted filtrate and astragalus ethanol liquid are combined and concentrated to make a dry paste, crushed, sieved, added zedoary volatile oil and fine powder of cinnamon and other drugs, and made into various preparations with medicinal excipients. The preparation can obviously inhibit the hyperplasia of prostate tissue induced by testosterone, significantly reduce the wet weight and dry weight of each leaf of the prostate, has no obvious toxic effect, and is safe and reliable; the preparation method has high bioavailability, good drug effect, stable quality and easy control.

The invention discloses application of prinsepia utilis royle in an anti-benign prostatic hyperplasia drug. Leaves of prinsepia utilis royle are dried under the temperature of 40 DEG C to constant weight, the leaves of prinsepia utilis royle are soaked into water with the weight being 8-16 times that of the leaves of prinsepia utilis royle for 0.5-1 h, reflux extraction is performed for 1-2 h, after filtering is performed through three-layer gauze, filtering is performed through a 100-mesh screen cloth, water with the weight being 8-14 times that of medicinal materials is added into residues to be subjected to reflux extraction, medicine liquid is filtered out, and filtrates are combined. The prinsepia utilis royle extract can treat hyperplasia of prostate, improve the estrogen / androgen proportion mainly by lowering the androgen level and enhance the body oxidation resistance.

The invention discloses a chrysanthemum total flavone granule, which is made of the following raw materials in the weight ratio: sucrose powder: dextrin: dry extract powder of the total flavonoids of chrysanthemum = 0.5-1.5: 1.5-2.5: 0.5-1.5 . The present invention prepares chrysanthemum total flavonoids into granules. The granules have good formability, properties, particle size, water content, solubility, etc. all meet the requirements, and the quality is controllable and the stability is good. The color changes, the smell is lost, the content of active ingredients decreases, and the color of the item in the soaking process does not turn green. Chuju total flavonoids granules can significantly prolong the coagulation time of rats with cold coagulation and blood stasis syndrome, reduce the length of thrombus in vitro and dry and wet weight, reduce hematocrit, slow down erythrocyte sedimentation rate, and increase serum NO content. The product is easy to drink and carry, easy to store, has no toxic and side effects, and has the characteristics of preventing, treating and improving abnormal blood rheology in rats with blood stasis.

The invention relates to the technical field of medicine research and development, in particular to application of a flavone C-glycoside compound in preparation of medicine for preventing or treating acute lung injury and / or acute respiratory distress syndrome, the flavone C-glycoside compound has a structure shown in the following formula, R1-R8 are defined in the specification, and the flavone C-glycoside compound has a structure shown in the specification. The flavone C-glycoside compound provided by the invention can obviously inhibit inflammatory response, inhibit release of inflammatory factors and reduce the content of inflammatory factors in alveolar lavage fluid and serum, and also can obviously inhibit pulmonary edema, reduce generation of pulmonary effusion and reduce wet weight of lungs; the increasing degree of the ratio of wet weight to dry weight of lung caused by acute lung injury is inhibited, so that the effects of resisting inflammation and inhibiting lung edema are achieved.

The invention discloses an active component for treating prostatic hyperplasia. The active component is beta-sitosterol-3-O-beta-D-glucoside, and is prepared through extracting a Long Stephania Herb medicinal material by using ethanol, and separating and purifying by using macro-porous resin and silica gel. The invention also discloses a medicine for treating prostatic hyperplasia. The medicine contains the active component. The beta-sitosterol-3-O-beta-D-glucoside can obviously reduce the prostate wet weight, the prostate volume and the prostate index of prostatic hyperplasia mice, has an obvious prostatic hyperplasia treatment effect, and has small toxic side effects.

The invention discloses a novel ferulic acid derivative, its application and a synthetic method thereof. The novel ferulic acid derivative is a compound as shown in the formula (I), wherein R1 and R2 are respectively C1-10 alkyl. According to the compound as shown in the formula (I), ferulic acid molecule is used as the base. By modification or reconstruction of the side-chain structure of the ferulic acid molecule, stability of ferulic acid is raised, and its pharmacological effects are substantially enhanced.

The invention provides a medicinal liquor for alleviating clinical symptoms of reddening and swelling and heat pain. The medicinal liquor has a formula containing 400-600 parts by weight of alcohol and the following medicinal materials immersed in the alcohol in parts by weight: 2-4 parts of rheum officinale, 2-4 parts of scutellaria baicalensis, 2-4 parts of phellodendron, 2-4 parts of coptis, 2-4 parts of garden burnet, 2-4 parts of white peony root, 4-6 parts of salvia miltiorrhiza and 4-6 parts of safflower. The medicinal liquor for alleviating the clinical symptoms of reddening and swelling and heat pain has substantial treatment effect, simple material selection and no toxic and side effects during clinical use.

The invention discloses an application of arctiin in preparation of a medicine for treating prostatic hyperplasia. Arctiin is a main active substance in fructus arctii, and it is found that arctiin can significantly reduce the wet weight and prostate index of prostate of a model animal and can be applied to treatment of prostatic hyperplasia. The arctiin is definite in curative effect and small in toxic and side effects, is expected to be developed into the prostatic hyperplasia medicine, and has a wide medical application prospect.

The invention relates to the technical field of medicines, in particular to application of a methyl flavonoid compound in preparation of a medicine for preventing or treating acute lung injury and / or acute respiratory distress syndrome. The methyl flavonoid compound provided by the invention has a structure as shown in the following formula: the methyl flavonoid compound can obviously inhibit inflammatory response, inhibit release of inflammatory factors IL-1beta, IL-6, TNF-alpha and MPO, reduce the content of inflammatory factors in alveolar lavage fluid and serum of mice with acute lung injury, and also can obviously inhibit pulmonary edema, so that the methyl flavonoid compound can be used for treating acute lung injury. The traditional Chinese medicine composition disclosed by the invention can be used for reducing the generation of lung effusion, reducing the wet weight of the lung and inhibiting the rising degree of the ratio of wet weight to dry weight of the lung caused by acute lung injury, so that the effects of resisting inflammation and inhibiting lung edema are achieved, the acute inflammatory injury of the lung can be effectively reduced, respiratory distress is delayed or weakened, and the symptoms of severe and critical patients are relieved; the medicine can be used for preventing or treating acute lung injury.

The invention relates to a disease preventing and curing medicinal mouth-muffle and a medicinal composite. The disease preventing and curing medicinal mouth-muffle (1) comprises a mouth-muffle body (2), one surface of the mouth-muffle body (2) is provided with an insert pocket (3), and a powder bag (4) which packages the medicinal composite is placed in the insert pocket (3). The medicinal composite comprises the following Chinese herbs by weight: 2.2 percent of chrysanthemum and muskiness, 4.2 percent of cinnamon, good ginger, long pepper, radix aconite, frankincense, myrrh and clove, 5.0 percent of vermilion, 6.4 percent of asarum, eaglewood, croton, resina draconis, early plum flowers and rhizoma ligustici wallichii and 7.6 percent of tooth soap, arsenic sulphide and brain sand. The disease preventing and curing medicinal mouth-muffle internally carries the medicinal composite which plays a role during the mouth-muffle wearing process, thereby having disease prevention and cure andbeing simple and direct and also effective in treatment.

The invention relates to the technical field of medicine research and development, in particular to application of a flavonoid compound in preparation of a medicine for preventing or treating acute lung injury and / or acute respiratory distress syndrome, the flavonoid compound has a structure as shown in a formula I, r1 is selected from H, a hydroxyl group, an alkyl group of C1-C8, a cycloalkyl group of C3-C10, an alkoxy group of C1-C8 and a glycosyl residue of C4-C20; r2 and R3 are independently selected from one of H, a hydroxyl group, an alkyl group of C1-C8, a cycloalkyl group of C3-C10 and an alkoxy group of C1-C8; and R4 is selected from an aryl group of C5-C20 or a substituted aryl group of C5-C20. The flavonoid compound can obviously relieve inflammatory response of mice with acute lung injury, reduce the ratio of wet weight to dry weight of lungs, inhibit lung edema caused by acute lung injury while resisting inflammation, and can be used as a potential medicine for preventing or treating acute lung injury.

The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicinal composition as well as a preparation method and an application thereof. The traditional Chinese medicinal composition is prepared from pseudo-ginseng, radix puerariae, radix paeoniae rubra, safflower carthamus, peach kernels, herba siegesbeckiae, dragon's blood, hematoxylon, rhizoma chuanxiong, earthworm, leech and radix achyranthis bidentatae. The preliminary pharmacodynamics study proves that the traditional Chinese medicinal composition and a medicine provided by the invention have obvious antithrombus effects (P is smaller than 0.05) in the aspects of prolonging the in-vivo thrombogenesis time, reducing the in-vitro thrombus wet weight and dry weight, and inhibiting the platelet aggregation effect, and therefore, the traditional Chinese medicinal composition has an obvious antithrombus curative effect (P is smaller than 0.05).

The invention relates to the technical field of medicine research and development, in particular to application of an isopentenyl flavonoid compound in preparation of a medicine, the medicine can be used for preventing or treating acute lung injury and / or acute respiratory distress syndrome, the isopentenyl flavonoid compound has a structure as shown in a formula 1, and definitions of R1-R10, M, X and k are recorded in the specification. The isopentenyl flavonoid compound provided by the invention can obviously inhibit inflammatory response, inhibit release of inflammatory factors, reduce the content of inflammatory factors in alveolar lavage fluid and serum, and also can obviously inhibit pulmonary edema, reduce generation of pulmonary effusion and reduce wet weight of lungs, so that the lung quality is improved. The increasing degree of the ratio of wet weight to dry weight of lung caused by acute lung injury is inhibited, so that the effects of resisting inflammation and inhibiting lung edema are achieved.