102 results about "Nutritional Supplementation" patented technology

This invention provides a bovine colostrum IgG nutritional supplement gummies and their preparation method, belonging to the field of functional food technology. The bovine colostrum IgG nutritional supplement gummies of this invention, through precise formulation of specific components, effectively improve the dispersion uniformity of whole-fat bovine colostrum freeze-dried powder in the gummy base, significantly retaining the activity of immunoglobulin G, giving the product a stable texture and good taste; further, combined with a special process adapted to the formula, high yield and high raw material utilization are achieved in industrial production. This product combines immune nutritional supplementation with convenient consumption, making it suitable for people of all ages and possessing good market application prospects.

A method of improving flavor of a combination of a composition for increasing circulating ketone levels is disclosed. A composition containing (D)-β-hydroxybutyric acid (D-BHB), (D)-β-hydroxyvaleric acid (D-BHV), and (D)-1,3 butanediol (D-1,3BD) is disclosed. Exemplary compositions may be incorporated into food, supplement, and beverage products.

The invention provides a biological bait culture method for pond culture water. The biological bait culture method comprises the following steps: S1, building a three-dimensional culture system; s2, preparing an ecological base and a biocenosis; according to the method, by building a three-dimensional cultivation system of the bottom layer modular net cage, the water surface floating type three-dimensional cultivation frame and the intelligent regulation and control system and combining scientific configuration of ecological bases and biocenosis, the problem that bait supply is unstable in traditional cultivation is effectively solved; the light organism cultivation unit, the plant planting unit and the biological membrane carrier unit of the water surface floating type three-dimensional cultivation frame work in a layered mode, bait organisms such as chlorella, copepods and rotifers in different water layers are cultivated in a directional mode, a complete closed-loop food chain is constructed in addition to food filtering and nutrition supplementing of snails and freshwater mussels, and the bait yield per unit water body is greatly increased.

Provided herein are methods for providing personalized nutritional supplementation to a subject. Also provided are compositions of personalized nutritional supplementation for subjects in need thereof.

Provided herein are methods for preventing or treating antibiotic induced dysbiosis in a patient by administering to the subject a composition comprising a micro sphere, a bio film-generating probiotic bacterium and a prebiotic, wherein the prebiotic comprises a nutritional supplementation for the probiotic bacterium.

A method for producing a nutritional supplement from microbial cells is disclosed. The method includes culturing microbial cells to obtain a biomass, incubating the biomass by heat treatment at a temperature between 55° C. and 80° C. for an incubation time between 10 and 60 minutes, and concentrating the biomass by separating and removing the liquid phase from the solid phase to obtain a dry matter content between 2% and 40% of the total weight of the nutritional supplement. A system for producing a nutritional supplement from microbial cells using the aforementioned method is also disclosed. The system includes a bioreactor, a heat exchanger, and a separator for carrying out each step of the aforementioned method.

The application discloses a method and system for generating a compound intervention scheme based on a pre-trained model and application thereof, wherein the compound refers to a nutritional supplement, a traditional Chinese medicine, a natural product with a medicinal value to be explored, or an old drug with a new use compound, and particularly refers to a method and system for generating a personalized nutritional supplement combination intervention scheme. The method of the application can successfully quantify and characterize the action of the compound, and the method of the application can also be applied to guide the medication of patients or a clinical nutrition scheme, for example, a patient infected with a novel coronavirus.

The application discloses a tricholoma matsutake mushroom and vegetable fresh composite seasoning and belongs to the field of food seasoning processing. The seasoning contains 7-15 parts of edible mushroom composite enzymatic extract, 5-15 parts of laminaria enzymatic extract, 35-45 parts of edible salt and other raw materials in terms of mass fraction; the edible mushroom composite enzymatic extract and the laminaria enzymatic extract are respectively prepared through a two-step enzymatic process, and the edible mushroom contains multiple rare mushroom species such as tricholoma matsutake and lentinus edodes. The seasoning takes rare edible mushroom and laminaria as the umami core, and is compounded with kale powder and fruit and vegetable powder, is rich in flavor and nutrition, and has the functions of seasoning and nutrition supplementing; the umami synergy is realized through the enzymatic process, the umami strength is high, and the taste is mellow; the raw materials are natural and free of chemical synthetic umami agents, the utilization rate of the raw materials is high, the clean label trend is met, the seasoning can be applied to the field of high-end soup bases and the like, and the product has high added value.

The invention discloses a natural spray for promoting blackening of white hair and growth of hair and a preparation method of the natural spray. The spray is prepared by compounding natural plant extracts of polygonum multiflorum, cacumen biotae, black sesame, fructus viticis, angelica sinensis, ginger, ligusticum wallichii, liquorice and the like, and clove or / and cinnamon extract is creatively adopted as a natural preservative flavor enhancer. Through a multi-target synergistic system of nourishing, blood activating and infiltration promoting and activating, anti-inflammation and stability maintaining, hair follicle melanocytes can be nourished from the source, white hair can be naturally turned into black, dormant hair follicles can be effectively activated, and hair growth is promoted. Preferably, ginseng and lucid ganoderma extracts can also be added to enhance the nourishing and stability maintaining effects. The invention aims to overcome the double defects in the prior art, and provides a multifunctional spray which is 100% purely natural and does not contain any chemically synthesized dye, oxidant, hormone, chemical preservative and harmful additive. The invention aims to realize natural blackening of white hair by gradually recovering melanin synthesis of hair follicles through exogenous nutrition supplement, and effectively promote hair growth and prevent hair loss by stimulating scalp microcirculation, resisting inflammation, relieving and directly activating hair papilla cells. The invention finally provides a daily care product which integrates blackening, hair growth and maintenance, is convenient to use (washing-free after spraying) and does not need to be cleaned. All the components are natural, safe and non-irritant, and the shampoo adopts a washing-free spray design, is convenient to use and is suitable for all hair qualities.

The invention relates to the technical field of biology, and discloses application of ascaroside in anti-aging, and the ascaroside can be widely applied to the fields of anti-aging foods, nutritional supplements and medicines. The invention reveals that ascaroside asc-C9 can play a cross-species conservative anti-aging effect from insects to mammals to a fermentation system for the first time, and the mechanism of ascaroside asc-C9 comprises promotion of mitochondrial function, enhancement of fat browning, improvement of antioxidant level and maintenance of cell energy steady state; the invention provides an anti-aging active molecule which is natural in source and clear in effect and a fermentation preparation approach thereof.

Composition comprising a combination of oleuropein or metabolite thereof and taurine or functional derivative thereof are provided. The composition may be an oral nutritional composition, for example a nutritional supplement, an oral nutritional supplement, a food product, a food for special medical purpose (FSMP). The composition can be administered to an individual in need thereof for improving a physiological state linked to metabolic fatigue in one or more cells, (ii) increasing mitochondrial energy and mitochondrial calcium uptake in one or more cells, and (iii) increasing antioxidant capacity, reducing oxidative stress and / or enhancing mitochondrial function, (iv) treating or preventing a calcium deficiency / depletion disorder in an individual. Additionally or alternatively, the method can treat or prevent a mitochondria-related disease or a condition associated with altered mitochondrial function in an individual in need thereof or at risk thereof.

The invention relates to the technical field of nutritional supplement preparations for pets, in particular to a high-activity non-denatured II-type collagen pet joint dispersible tablet and a preparation method thereof. According to the technical scheme, the soft capsule is prepared from the following raw materials in percentage by weight: 4.0%-7.0% of non-modified II type collagen, 4.0%-6.0% of sodium chondroitin sulfate, 4.0%-6.0% of green lip mussel powder, 0.5%-1.5% of sodium hyaluronate, 30%-40% of microcrystalline cellulose, 12%-18% of sodium carboxymethyl starch, 15%-22% of sweet potato starch, 4.0%-6.0% of polyvinylpolypyrrolidone, 6.0%-10.0% of enzymolysis chicken liver powder, 2.0%-4.0% of yeast extract, 1.5%-3.5% of lactose goat milk powder and 0.3%-0.7% of magnesium stearate. A core active component structure is protected by virtue of nano embedding and a whole-course low-temperature process, and a dual joint maintenance path of immunoregulation and nutrition supplement is constructed.

This application relates to a bile filtration and collection device with heat preservation for bile reinfusion, belonging to the field of medical device technology. The bile filtration and collection device with heat preservation for bile reinfusion of this application includes a stirring assembly, a heating assembly, a filtering assembly, and a nutrient assembly. The stirring assembly includes a stirring drum and a stirrer, with the stirrer configured to rotate within the inner cavity of the stirring drum. The heating assembly includes a heating base disposed below the stirring drum for heating the bile within the drum. The upper end of the filtering assembly communicates with a bile drainage bag, and the lower end communicates with the inner cavity of the stirring drum for filtering the bile. The nutrient assembly is disposed around the periphery of the stirring drum for delivering nutrients into the drum. The bile filtration and collection device with heat preservation for bile reinfusion provided by this application utilizes the filtering assembly, nutrient assembly, stirring assembly, and heating assembly to perform bile filtration, nutrient supplementation, stirring, and heating, improving the convenience and comfort of bile reinfusion and enhancing the patient's treatment efficacy and comfort.

The invention discloses a full-peptide compound preparation for nourishing heart and cerebral vessels. The full-peptide compound preparation comprises a core layer and an outer coating, the core layer contains Yang tonifying and Yang recuperating decoction source small molecule peptide and modern bioactive components, and the outer layer is a moisture-proof, slow-release or enteric coating. The preparation is stable in structure and good in absorption and utilization effect, is suitable for the fields of functional foods, health foods, special diets and the like, and has a good industrialization prospect.

This invention belongs to the field of microbial technology and provides a space-mutated *Bacillus paralichrysiformis* strain with high synthetic selenocysteine ​​and high sodium selenite tolerance, obtained through space mutagenesis, and its applications. The *Bacillus paralichrysiformis* G1-m strain is deposited at the China General Microbiological Culture Collection Center (CGMCC) with accession number CGMCC No. 36525, deposited on November 11, 2025. This strain has significant core advantages: firstly, it possesses extremely high sodium selenite tolerance, able to withstand sodium selenite stress up to 440 mM; secondly, its selenocysteine ​​and nano-selenium synthesis efficiency is significantly improved, not only significantly increasing the strain's resistance threshold to selenium stress but also directionally enhancing the activity of the selenocysteine ​​biosynthetic pathway. Its application potential covers multiple fields, such as selenium-enriched probiotic preparations, nano-drug carriers, functional food additives, and high-efficiency selenium nutritional supplements, laying the foundation for the high-value utilization of selenium resources and the industrial application of functional microorganisms.

This invention provides a composition containing vitamins and minerals, comprising vitamin D, folic acid, vitamin B12, potassium, and excipients in specific proportions. The invention may also include vitamin B1 and vitamin B2. The components of this composition have a synergistic effect in preventing hypertension, particularly in preventing hypertension accompanied by elevated homocysteine ​​levels. Furthermore, this composition can also be used for targeted nutritional supplementation in specific populations.

A moisture-proof acetyl-L-carnitine, comprising not less than 10% of acetyl-L-carnitine, or a hydrochloride thereof, or a mixture of both by weight. The preparation method comprises mixing the following components by prescription amount: acetyl-L-carnitine, or a hydrochloride thereof, or a mixture of both, one or more adjuvants selected from microcrystalline cellulose, compressible starch, lactose or mannitol, one or more adjuvants selected from silicon dioxide, magnesium stearate, calcium hydrogen phosphate, calcium silicate, and micro-powder silica gel; granulating; obtaining the moisture-proof acetyl-L-carnitine. The moisture-proof acetyl-L-carnitine is formulated into a nutritional supplement, a food, a beverage, or an animal feed.

The present invention provides compositions and dosage forms for enhancing energy and reducing inflammation. In certain embodiments, an energy composition comprises citicoline and paraxanthine in a mass ratio of 10:1 to 1:10, preferably about 1:1, delivered as an oral film, capsule, or liquid; exemplary unit doses deliver about 200–300 mg citicoline and about 200–300 mg paraxanthine. In further embodiments, an anti-inflammatory composition comprises astaxanthin, L‑citrulline, glutathione, luteolin, and palmitoylethanolamide within defined mg ranges. Liposomal and spray‑dried liposomal microparticle formulations, including reconstitution parameters, are provided. The compositions yield synergistic effects relative to individual actives, as quantified by accepted models (e.g., combination index <1). Methods of manufacturing, kits, and methods of improving mental focus, physical performance, and recovery are also described.

The present invention provides a system, a kit and a use thereof for oral mucosa delivery of a composition. The composition may comprise at least two sub-compositions admixed right before dispensing to the oral mucosa. In one embodiment, the system is a pressurized system. In another embodiment, the admixed sub-compositions are atomized. In one embodiment, one of the sub-compositions comprise a beneficiary gas, such as oxygen. In another embodiment, one of the sub-compositions comprise a nutritional supplement, a nutraceutical composition, a pharmaceutical composition, or any combinations thereof.

The application discloses a kind of planting methods for improving the content of Dendrobium candidum polysaccharide, covers seedling pretreatment, substrate preparation, light temperature water stress regulation, microbial reinforcement, selenium-silicon nutrition supplement and intelligent harvesting decision.By red light / blue light combination (3:1) and pulse drought activation secondary metabolism, inoculate beta-fructan endophyte Paenibacillus polymyxa and add chelated selenium-silicon foliar fertilizer, combined with low temperature and low humidity adversity in the later growth stage, the stem polysaccharide content reaches 38%-42%.System integration LED light source, EC sensing irrigation and bacterial agent spraying equipment, realize standardization production.Embodiment shows that the method is 35-40% higher than traditional planting polysaccharide, and there is no gene editing risk, in line with GAP specification.

This invention belongs to the field of biomedical technology, specifically involving the application of the MRPL41 gene / protein in the preparation of drugs for treating age-related sarcopenia. This invention is the first to demonstrate that MRPL41 is a key rate-limiting factor in the assembly of mitochondrial ribosomes in aging muscle satellite cells, establishing it as a core target for the treatment of age-related sarcopenia. Overexpression of MRPL41 can promote the assembly of mitochondrial 55S holoenzymes, improve the translation efficiency of mitochondrial-encoded proteins, repair mitochondrial dysfunction at its source, thereby promoting muscle repair, improving muscle atrophy, and achieving the treatment of age-related sarcopenia. This invention provides a precise microscopic target for the treatment of age-related sarcopenia, overcoming the limitations of existing clinical therapies (such as hormone replacement and simple nutritional supplementation) due to significant side effects and "anabolism resistance," providing a new direction for the development of innovative drugs specifically for the treatment of age-related sarcopenia, and has excellent application prospects.

A medication dispensing device comprising a rotating platform configured for receiving a plurality of medication dispensing containments housing a plurality of pills comprising medication or supplements, and a scanner or user input for identifying the one or more medication containments and receiving data specific to the medication or supplements provided therein, wherein the medication containment has a lower surface with a dispensing opening and pill capture head sized according to at least one dimension of the plurality of pills contained therein, and a medication sweeper disposed above the pill capture head and between the plurality of pills so as to selectively direct is single pill out the dispensing opening while blocking a remainder of the plurality of pills in the containment. A motor-driven first gear is coupled to the pill capture head and medication sweeper such that rotation of the gear affects rotation of the pill capture head with respect to the medication sweeper to dispense the single pill, wherein the motor receives commands from data acquired by the scanner to affect dispensing of the single pill.

The invention relates to the technical field of application of natural active substances, in particular to application of octyl gallate in preparation of products for strengthening brain and improving intelligence. According to the application of the octyl gallate in preparation of the products for strengthening the brain and improving intelligence, the oxidative stress level of brain tissue and neuroinflammation response can be effectively relieved, and therefore learning and memory impairment and cognitive function decline caused by chronic sleep interference are improved. The invention finds that the octyl gallate as a polyphenol active substance has good intelligence-promoting and health-care effects, and can be used for preparing health-care foods, functional foods or nutritional supplements for improving learning memory and relieving cognitive dysfunction within a certain dosage range. The octyl gallate is clear in raw material source, can be obtained through natural extraction or chemical synthesis, and has the advantages of being high in safety, wide in application range, remarkable in economic value and the like.

To provide safe and effective compositions and methods for enhancing the efficacy and / or reducing the side effects of cancer chemotherapy and increasing the sensitivity of chemotherapy-resistant cancer cells.SOLUTION: Nutritional supplements comprising fish oil and selenium have been found to provide various activities that are beneficial in treating cancer and related conditions. The supplement provides a synergistic effect in reducing cancer cell growth when used in combination with a chemotherapeutic agent and can reduce growth in drug resistant cancer cells when used in combination with a chemotherapeutic agent to which the cells are resistant. Effects in reducing angiogenesis, reducing metastasis, decreasing the number of circulating cancer cells, and altering AXL signaling have also been found. The use of the supplement was found to reduce the wasting associated with cachexia and decrease circulating cytokines associated with inflammation. The overall effect was found to prolong survival in a clinical study.SELECTED DRAWING: Figure 1

A composition contains Nicotinamide and pyridoxine. The composition may be an oral nutritional composition, for example a nutritional supplement, an oral nutritional supplement, a food product, a food for special medical purpose (FSMP). The composition can be administered to an individual in need thereof orally or intravenously for preventing and / or treating sarcopenia, physical frailty, a loss of and / or improving skeletal muscle mass, lean muscle mass, skeletal muscle strength and / or skeletal muscle function.

Nutritional supplements and compositions for activating cellular signaling genes in innate inflammatory pathways are described in this application. In particular, this application describes a composition containing a solid portion comprising Bacopa monnieri extract having a least 20 percent bacosides, Silybum marianum (milk thistle) extract having 70 percent to about 80 percent silymarin, milk thistle extract, Withania somnifera (ashwagandha) extract, Camellia sinensis (green tea) extract containing at least 40 percent epigallocatechin gallate and about 98 percent polyphenols; and Curcuma longa (turmeric) extract containing at least about 95 percent curcumin. The compositions also comprise a liquid portion comprising fish collagen peptides comprising about 90 percent protein and Formosa ruby quinoa water extract containing about 10 wt % extract and about 90 wt % water. These compositions improved the skin and impacted key regulatory genes associated with several important cellular pathways. Other embodiments are also described.

The present application relates to a kind of method for extending shelf life of sweet potato leaf beverage by orange powder, the present application will be orange powder and sweet potato leaf beverage collocation, both have very good antioxidant, protect cardiovascular and cerebrovascular, improve immunity and the synergies such as nutrition supplement.If orange peel can be successfully applied to beverage, it will greatly reduce the waste of orange peel, play the role of environmental protection, and the preparation process of natural high-purity orange antioxidant is simple and economical, very suitable for the simple improvement of product and process of food enterprise.In addition, this drink has specific functional characteristics, in line with the "big health" direction of "food and medicine homology".Finally, the present application proves the antioxidant influence law of different parts of orange powder on sweet potato leaf beverage, provides a basis for the production of other natural antioxidants, and has high practical value.