47 results about "Membrane function" patented technology

A nutritional supplement composition for normalizing impaired or deteriorating neurological function in humans is composed of: at least one agent which promotes synthesis of ATP and/or creatine phosphate in the body, at least one antioxidant for scavenging free radicals in at least one pathway in the body; at least one agent for normalizing or maintaining membrane function and structure in the body; at least one agent for normalizing or maintaining normal neurotransmitter function in the body; at least one agent for down-regulating cortisol action; and at least one agent for suppressing activation of apoptotic pathways in the body. The composition may further contain one or more of: at least one agent for suppressing inflammation in the body; at least one agent for normalizing or maintaining vascular wall function and structure in the body; at least one agent for normalizing or maintaining function of nerve growth factors and/or neurotropic factors in the body; at least one agent for suppressing toxic metal ionic effects; at least one agent for normalizing or maintaining methyl metabolism in the body; at least one agent for normalizing or maintaining metabolism of insulin and glucose in the body; and at least one agent for up-regulating activity of heat shock proteins in the body. A method for normalizing impaired neurological function in humans modulating nutrient partitioning in a human involves administering the aforementioned composition to the human, preferably on a daily basis, for a therapeutically effective period of time. Preferably, the method further involves having the human follow a stress reduction program, and/or a cognitive retraining program, and/or a dietary program designed to maximize insulin and glucose metabolism.

Embodiments of the invention are related to anion exchange membranes used in electrochemical metal-air cells in which the membranes function as the electrolyte material, or are used in conjunction with electrolytes such as ionic liquid electrolytes.

Disclosed are a novel bionic hepatic tissue engineering scaffold and a interface, and producing method thereof, comprising designing a hepatic tissue engineering scaffold imitating natural hepatic lobule structure, and arranging two separate sets of micro duct structure and a interface thereof for hepatocytes and endothelial cells inside the scaffold. The micro duct interface of endothelial cells can be connected with blood vessels in the nature liver, or with the circulatory system of a bioreactor. The hepatocyte micro duct structure is used for accelerating hepatocyte diffusion when perfusing hepatocytes. A mono-layer flow passage and a interface are produced by press print method, and then pore space between two micro duct structures is formed by freeze drying, so that the porosity factor of the material is increased to make the material have certain semi-permeable membrane function. The three-dimensional scaffold and the interface thereof with hepatocyte micro duct structure and endothelial cell micro duct structure are produced by lamination bonding process.

The invention discloses an expression structure method for constructing Glial cell line-Derived Neurotrophic Factor (GDNF) fusing penetrating peptides, the purification of an expressed protein product and the significance thereof, which is mainly characterized in that (1) GDNF parent is a human source mature type; (2) the N-tail end of the GDNF is fused with PEP-1 penetrating peptides comprising the 21 amino acid; and the expression product of the constructed penetrating peptides GDNF fusing the gene expression plasmid has the membrane penetrating function and biological function of GDNF and can be clinically applied in the treatment of the related diseases.

The invention discloses a GO (graphene oxide) and g-C3N4 composite modified membrane material. A preparation method includes steps: activating an original membrane to recover original membrane flux; adding a surfactant into GO and g-C3N4 mixed dispersion liquid to obtain mixed liquid; soaking the activated original membrane into the mixed liquid to realize ultrafiltration adsorption, and soaking the membrane into aniline hydrochloric acid solution; taking out after soaking is finished, and soaking in hydrochloric acid solution of ammonium persulfate immediately to enable interface polymerization reaction; finally, drying the membrane to obtain the composite modified membrane material. By an ultrafiltration adsorption and interface polymerization combined modification method, GO and g-C3N4are combined for surface composite modification of the membrane material, and a visible light responsive catalytic modified membrane is developed. The novel modified membrane is low in preparation cost and recyclable, pollution resistance is remarkably improved, firmness in modifying agent and photocatalyst loading is achieved, the visible catalytic performance and hydrophilic performance are remarkably enhanced, the forbidden bandwidth of a membrane function layer is decreased, the problem of secondary pollution is avoided, and a promising application prospect is achieved.

The invention discloses a liquid membrane extraction method by taking a hollow fiber composite membrane as a liquid membrane carrier. According to the liquid membrane technology, the hollow fiber composite membrane serves as the liquid membrane carrier, an extract phase is filled and attached to the gap and surface of the hollow fiber composite membrane to form the liquid membrane, a feed liquid phase solution and a reverse extraction phase respectively flow through two sides of the carrier, and the separation effect of in-step extraction and reverse extraction is realized through the liquid membrane function. The hollow fiber composite membrane consists of a braided tube layer and a polymer membrane layer; and meanwhile, the extraction phase and the feed liquid phase are fully mixed before entering the membrane by utilizing a mixer, the dispersing effect of the extraction phase liquid drops in the feed liquid phase is improved, the contact probability of the liquid membrane and the feed liquid solution is enhanced, and the mass transfer efficiency is improved. The imbalanced extraction realized by the liquid membrane technology is utilized, the problems that the liquid membrane attachment amount is small, the liquid membrane is instable, the mass transfer efficiency is low and the like in the hollow fiber supported liquid membrane and the liquid membrane updating technology are solved, the mass transfer coefficient and liquid membrane flux are improved, and the magnitude order of the mass transfer coefficient is 10-5.

The invention belongs to the field of membrane separation and relates to a ceramic base carbon nano tube inorganic composite membrane and a preparation method thereof. According to the invention, a carbon nano tube is used as a membrane function layer, porous ceramic is taken as a base body, superpolymer is taken as a reinforcement material, and a method of coating, dipping and reinforcing, and high temperature carbonizing is adopted, so that the ceramic based carbon nano tube inorganic composite membrane of which the pore diameter is controllable and the porosity factor is 70 to 90 percent is obtained. The ceramic base carbon nano tube inorganic composite membrane has excellent adsorptive property and electric conductivity, and has high membrane permeability and selectivity. According to the invention, loss of porosity factor during the traditional membrane preparation process can be avoided, the mechanical property of the membrane is enhanced, and the preparation method has the advantages that the preparation technology is simple and mass production is facilitated.

The invention discloses a restructuring protein with phenotypic knock-up effect for chemotactic factor acceptor CXCR4 and constructing method, which is characterized by the following: proceeding twice genetic reform for restructuring muton SDF-1/54R of SDF-1 alpha with CXCR4 antagonistic active; constructing the restructuring protein 54R/Tat/KDEL with SDF-1/54R, high effective wearing film carrier Tat(47-57) and endoplasmic reticulum locating fragment KDEL; utilizing high effective wearing film function of Tat(47-57) and endoplasmic reticulum locating function of KDEL; leading CXCR4 specific antagonist SDF-1/54R into breast cancer cell; reaching the goal of phenotype knock up film surface CXCR4; laying necessary work foundation for blocking-up breast cancer transition.

The invention belongs to the field of a plant cell engineering technology and molecular biology and relates to a method for building a Chinese cabbage genetic transformation system by cell-penetrating peptide and microspore culture. The method comprises carrying out in-vitro synthesis of a transfection complex by film-penetrating functions of cell-penetrating peptide, adding the transfection complex into a separated microspore suspension liquid, preparing a regeneration plant by a free microspore culture technology and carrying out identification on the regeneration plant. The method builds the Chinese cabbage genetic transformation system based on free microspore culture, provides a study platform for Chinese cabbage genetic breeding and lays the method foundation of Chinese cabbage functional genomics.

The invention provides a method for detecting the injury of the mitochondria of the sperms of fishes, which relates to an aquaculture technology and needs to provide a method for detecting the injury of the mitochondria of the sperms of fishes. In the invention, the sperms of the fishes with a certain number are collected. The method is characterized by comprising the following steps of: after washing a sperm specimen by using PBS, centrifuging by 300*g for 5min; and suspending by the PBS, precipitating the sperms, regulating the density of the sperms to be 1*106/ml, adding Rhl23, hatching for 10min in a water bath with the temperature of 37 DEG C, centrifuging, removing supernatant, washing by the PBS repeatedly, centrifuging, suspending by the PBS, adding PI and dyeing for 5min. The sperms with the normal mitochondria and the injured mitochondria are dyed by adopting a fluorescent double-dyeing method and are directly detected by using a flow type cell analyzer after being preprocessed, and the sperms with favorable mitochondrial membrane functions, the sperms with lost mitochondrial membrane functions and the sperms with necrosis can be quantitatively distinguished.

The invention provides a regulation and control method of a quantum well and quantum dot material energy band structure. The regulation and control method comprises the following steps: step 1, sequentially growing a sacrificial layer, a stress introduction layer and a quantum structure film functional layer on a substrate by using a vacuum deposition method; step 2, etching the stress introduction layer and the quantum structure film function layer to the sacrificial layer by using wet etching or dry etching through photoetching an opening area of the sacrificial layer; step 3, corroding a part of the sacrificial layer through the opening area by using a chemical method, releasing the stress introduction layer and the quantum structure film functional layer, and forming a curled structure or a folded structure by the stress introduction layer and the quantum structure film functional layer through prestress release; and step 4, preserving the device with the curled structure or the folded structure by using a supercritical drying method. The quantum structure film functional layer is made of a quantum well material or a quantum dot material, and in the step 3, different curled structures or folded structures are obtained through different corrosion parameters.

The invention discloses a planting method of a selenium-enriched Luhe green plum. The planting method comprises the steps: uniformly mixing miscellaneous manure or composted human and animal manure, phosphorus powder, lime and surface soil, and carrying out refilling to prepare a planting substrate; and then, selecting plants, and carrying out field planting and water and fertilizer management. Manure such as foliage top-dressing and calcium is replenished during the growth period of the Luhe green plum, so that green plum plants are promoted to be heightened, the quality and amount of fresh roots are improved, it is beneficial to the growth and development, and the economic benefit of green plum production can be obviously increased; an artificial chemical fertilizer is replaced with a natural nutrient substance contained in an extract, and the natural nutrient substance is beneficial to the absorption of the plants and has no hazards to the environment; and the effect of a cell for removing superoxide radicals is improved, the plasma membrane function is protected, and fruit senescence is delayed. Therefore, a high-quality selenium-enriched Luhe green plum product is obtained.