260 results about "Functional modification" patented technology

The invention discloses a preparation method and an application of a nano material monolithic column immobilized enzyme biological micro-reactor. The preparation method comprises the following steps of firstly, preparing a porous organic polymer monolithic column by using a mixed solution of a functional monomer, a crosslinking agent, a pore forming agent and an initiating agent through in-situ thermal-initiated or light-initiated polymerization in the column, and then bonding a nano material after functional modification to obtain a nano material monolithic column; and secondly, realizing immobilization of the enzyme on the monolithic column by using the nano material as an intermediate ligand to obtain the nano material monolithic column immobilized enzyme biological micro-reactor. The biological micro-reactor is successfully applied to proteomic analysis, medicament chiral resolution and catalyzed ester exchange reactions. The biological micro-reactor disclosed by the invention has the following advantages that the preparation method is simple, the immobilization amount of the enzyme is large, the catalytic activity is high, the enzymolysis speed is high, the efficiency is high, the service life is long, and the biological micro-reactor can be reused.

The invention discloses a preparation method of a magnetic antiphase demulsifier. The preparation method is characterized by firstly, preparing monodisperse ferroferric oxide magnetic microspheres by a hydrothermal method; secondly, coating a layer of thin silicon dioxide on the surfaces of the monodisperse ferroferric oxide magnetic microspheres, synthesizing magnetic microspheres with nuclear shell structures, performing group functional modification on the nuclear shell magnetic microspheres by using a silane coupling agent KH560; at last, performing grafting reaction by using the activity of functional groups and an antiphase demulsifier to obtain the magnetic antiphase demulsifier; the magnetic antiphase demulsifier prepared by the preparation method can improve the efficiency of original antiphase demulsifiers and has the characteristics of easy separation, high oil removing rate, obvious separation effect to oil-containing sewage, little use amount and high efficiency.

The invention discloses a carrier for immobilization as well as a preparation method thereof and immobilized beta-glucosaccharase. The carrier for the immobilization comprises magnetic nano particles, a carboxyl-rich composite material and transitional metal ions, wherein the carboxyl-rich composite material wraps the surface of the magnetic nano particles to form a carboxyl-rich shell, carboxyl on the surface is complexed with the transitional metal ions, and the transitional metal ions are combined with to-be-immobilized enzyme through a metal ion coordination bond. The preparation method comprises the following steps of (1) preparing the magnetic nano particles; (2) carrying out hydroxyl functional modification for the particles; (3) carrying out epoxy functional modification for the particles; (4) carrying out carboxyl functional modification for the particles; (5) complexing the particles with the transitional metal ions. The functional carrier is combined with beta-glucosaccharase through the metal coordination bond to obtain immobilized beta-glucosaccharase. The biological enzyme is firm in combination, high in enzyme activity, strong in operation stability and suitable for the mass production.

The invention discloses a preparation method and application of a three-dimensional graphene electrode for an electrochemical biosensor. The preparation method comprises the following steps of: fixing spongy graphene in which industrially produced foam nickel is taken as a substrate and which has a three-dimensional structure and is synthesized through chemical vapor deposition on a glass or quartz sheet; connecting the spongy graphene with the three-dimensional structure and a wire by using a silver conductive adhesive; and coating organic silica gel on a connection point of the metal wire and the graphene for insulation to obtain a spongy graphene electrochemical electrode with the three-dimensional structure. The three-dimensional spongy graphene electrode has the outstanding characteristics of high conductivity, high specific surface area, high electrochemical stability and the like, is easily subjected to surface functional modification, and has high detection sensitivity to dopamine and nicotinamide adenine dinucleotide; and a highly sensitive electrochemical biosensor for non-enzymatically and selectively detecting glucose can be obtained after the surface of the electrode is modified by Co3O4.

The invention relates to a mixed matrix type cation exchange membrane and a preparation method thereof. The cation exchange membrane takes a sulfonated modified polymer material as a substrate and isdoped with Schiff base type covalent organic framework materials loaded with different functional groups. The preparation method comprises the following steps of: sequentially performing monomer preparation and polymerization of a covalent organic framework material, sulfonation modification of a polymer, uniform mixing of the covalent organic framework material and a sulfonated polymer, and flow-spreading film formation; and finally, performing acid treatment to obtain the cation exchange membrane. The covalent organic framework material can effectively improve the vanadium resistance of themembrane based on the rigid porous structure; the organic porous structure of the covalent organic framework and the different functional modifications can partially compensate the loss of membrane proton conductivity caused by the introduction of particles; the rigid framework can obviously inhibit the swelling in the membrane and can improve the tensile strength of the membrane; COFs is composedof organic structures and can promote compatibility between sulfonated polymers and covalent organic framework materials; and moreover, the polymer as the substrate can improve the film forming performance of the covalent organic framework material, so that the covalent organic framework material has the better mechanical strength.

The invention relates to a functional improvement method of woods, in particular to a manufacturing method of a carbonization heat treatment-modified solid wood flooring, belonging to the technical field of functional modification of the woods and wood product processing. The technical solution for the manufacturing method comprises the following steps: (1) a solid wood flooring blank manufacturing step; (2) a drying step; (3) a carbonization heat-treatment improving step; and (4) a solid wood flooring manufacturing step. Due to the technical solution for the manufacturing method of a carbonization heat treatment-modified solid wood flooring, a production method of a solid wood flooring designed special for fast-growing woods while the existing technical problems are solved. Compared with the prior art, the manufacturing method has the advantages of simple production process, short production cycle, low energy consumption, low production cost and the like, and technical indexes of obtained solid wood flooring made of fast-growing woods achieve the national standard quality requirement.

The invention discloses a cross-linked hollow fiber anion exchange membrane and a preparation method thereof. The preparation method is characterized by comprising the steps that an aromatic polymer subjected to halomethylation is dissolved in an organic solvent, and a membrane casting solution is formed; the membrane casting solution is subjected to dry-wet spinning, a hollow fiber basement membrane is obtained, cross-linking and positively charged modification are conducted on the hollow fiber basement membrane through a one-step or two-step method, and the cross-linked hollow fiber anion exchange membrane is obtained finally. According to the cross-linked hollow fiber anion exchange membrane and the preparation method thereof, the basement membrane and a modified functional agent which are high in activity are selected, and by means of a nucleophilic substitution reaction between the basement membrane and the modified functional agent, functional modification to the basement membrane can be achieved under a very mild condition. The method has the advantages of being simple in process and low in cost, and meanwhile the prepared membrane has a good diffusion permeability property and has a large-scale application prospect in the field of acid recovery.

The invention discloses a multi-element functional modification polyvinyl alcohol-based lithium ion battery aqueous binder and application of the binder in an electrochemical energy storage device. According to the binder, polyvinyl alcohol is taken as substrate, and hydrophilic monomers and oleophylic monomers are taken as functional modification monomers. Through adoption of Michael addition reaction modification preparation, the binder has good water solubility, elasticity and bonding performance. Through application of the binder in the preparation process of the lithium ion battery electrode plate, the homogeneity of electrode slurry can be improved. Therefore, the electrode slurry can form film on a current collector evenly and flatly, the material of the electrode plate will not fall off, the capacity will not be reduced, the high rate capability and circulation stability of the lithium ion battery cathode and anode materials can be greatly improved, and the service life of the battery can be effectively extended.

The invention discloses a functional polymer containing phosphorylcholine and PEG and a method for forming a biological pollution resistant interface. The polymer is a functional polymer that contains multiple function groups on a side chain and has a controllable proportion; a PEG flexible chain with larger steric hindrance and outer cell membrane phosphorylcholine hydrophilic group interact to achieve good anti-pollution effect; the polymer contains less than 10% of catechol group, and can be strongly combined with surfaces of various polydopamine-mediated base materials to form a stable hydrophilic monomolecular coating, so that the functional modification of material surfaces is implemented. The method for forming coatings is simple; the coatings can exist on the surface of any base material, so that the ability of resisting adhesion and pollution of multiple biological ingredients of the material surface is improved.

The invention discloses a new synthesis method of a polyaniline/carboxylated graphene composite material and belongs to the technical field of composite materials. Firstly, functional modification is conducted on the surface of graphite oxide through NaOH and monochloroacetic acid to convert an epoxy group, a hydroxide group and other oxygen-containing groups on the surface of graphite oxide into carboxyl groups; secondly, graphite oxide is wrapped by a surfactant, and then the carboxyl groups are grafted onto the edge of graphite oxide together with diazonium salt, and carboxylated graphene is obtained; lastly, the carboxylated graphene and an aniline monomer are polymerized, and the polyaniline/carboxylated graphene composite material is prepared. According to the composite material, polyaniline is loaded on the surface of graphene and connected with graphene under the action of a covalent bond; the composite material has a large specific surface area, a novel structure and good electrochemical properties, mechanical properties and chemical stability, and can be used for preparing a supercapacitor, a selective absorbent for specific ions, a catalyst and the like.

The invention relates to a functional separator for a lithium sulfur battery, and a preparation method and application thereof, belonging to the technical field of electrochemistry. The functional separator of the invention is composed of a polymer separator matrix and a functional modification layer applied one side surface of the polymer separator matrix, wherein the functional modification layer comprises a binder, a conductive carbon material and a dendritic branched macromolecule. The adhesive of the invention has good adhesion and high stability. The conductive carbon material has a veryhigh electron conduction rate, can improve the utilization rate of the active substance and greatly reduce the internal impedance of the battery. The dendritic branch macromolecule contains more organic functional groups, the dendritic branched macromolecule has chemisorption to the polysulfide generated in the sulfur positive electrode region during the cycle, and the carbon material has physical adsorption to the dissolve polysulfide, thereby effectively inhibiting the shuttle effect in the lithium-sulfur battery. Therefore, the lithium sulfur battery prepared using the functional separatordescribed in the present invention exhibits excellent cycle performance and rate performance.

The invention discloses graphene modified waterborne polyurethane resin and a preparation method thereof. The preparation method specifically includes: subjecting graphene oxide obtained through a Hummers method to functional modification and dispersing to obtain a high-concentration graphene aqueous dispersion; adding polyester polyol (or polyether polyol) and a hydrophilic chain extender which are of formula ratio into the graphene aqueous dispersion, evenly stirring, and removing moisture under a vacuum condition; feeding nitrogen immediately after the vacuum condition is ended, adding diisocyanate of formula ratio, performing heating and stirring reaction for a certain time, then stopping nitrogen feeding, and adding a neutralizing agent; adding deionized water, performing high-speed dispersing for a certain time, then adding a small-molecule chain extender to perform reaction, and discharging. The preparation method has the advantages that the method is simple and controllable inoperation and capable of easily preparing and synthesizing the graphene modified waterborne polyurethane resin in a large-batch manner; the graphene modified waterborne polyurethane resin prepared bythe method is good in adhesive force, corrosion resistance and impact resistance and widely applicable to fields such as the marine field, steel structures, anti-static coating, conductive coating andantifouling and waterproof coating.

The invention provides a carbon material film with high electric conductivity, heat conductivity and strength and a preparing method thereof. The carbon material film is prepared according to the steps of adding functional carbon material powder and a dispersant to a solvent to be mixed and stirred; adding a binder and a plasticizer, and conducting mixing to obtain uniform and stable slurry; forming a blank film; placing the blank film in the solvent for reaction; evaporating the solvent; increasing temperature to 1000-3000 DEG C for sintering lasting 1-10 h to obtain the carbon material film. Through functional modification and then tape-casting and sintering of the surface of the carbon material, active groups between different sheets of the carbon material react with one another to form chemical bonds, and a carbon net stable structure is formed finally so that different sheets of the carbon material can be connected in the true sense. In this way, the mechanical strength, electric conductivity and heat conductivity of the carbon material film are improved greatly.

A polystyrene microsphere is provided. The polystyrene microsphere is micron or nano-scale, and the surface of the microsphere is coated with a polyacrylic resin Eudragit. The polystyrene microsphereof the present invention is a polystyrene microsphere with very low non-specific adsorption, and the surface of the microsphere contains a functional group carboxyl group, so that further functional modification of the surface of the polystyrene microsphere is not required, the operation is further greatly simplified, and the loss is reduced.

The invention belongs to the technical field of inorganic materials and bioanalysis and in particular relates to an aminophenylboronic acid surface-modified nano-carbon material, as well as a preparation method and application thereof. According to the invention, an available nano-carbon material is subjected to carbodiimide reaction on the basis of acid treatment. Firstly, the surface of the nano-carbon material is modified by polylysine and polyethylene glycol/diglycolic acid, then the nano-carbon material reacts with aminophenylboronic acid for surface functional modification of the nano-carbon material. The synthesis method provided by the invention is simple and efficient. The prepared aminophenylboronic acid-functionalized nano-carbon material, as a nano-adsorbent, has a large specific surface area and strong selective specificity, exhibits better dispersibility and stability in aqueous solutions, and can rapidly achieve the effect of specifically separating and concentrating glycopeptide/glycoprotein. The material is significant in use value and application prospects in the glycoprotein proteomics field and the like.

The invention discloses a composite particle with multiple core-shell structures. The composite particle uses inorganic silica nanoparticles as a core, uses an organic acrylate polymer as a middle layer, and uses a carbon nanotube adsorption layer as a shell. The invention also discloses a preparation method for the composite particle, first nano-silica is synthesized through a Stober method, thenthe surface of nano-silica is coated with an acrylate polymer layer based on a dispersion polymerization method, and an initiator that can be subjected to hydrolytic ionization is used to achieve coating of the nano silica surface with the polymer and charge modification in one step, then further carbon nanotubes are adsorbed through electrostatic self-assembly. The invention provides the composite particle with multiple core-shell structures and the preparation method thereof, the preparation process is green and efficient, and does not need complicated functional modification, and the prepared composite particle has excellent overall performance.

The invention provides a composite zinc cathode with an inorganic functional modification layer in a water system battery and a preparation method thereof, and application of a composite zinc cathodewith an inorganic functional modification layer in a water system battery. The composite zinc cathode comprises a base layer and a modification layer located on the base layer; the material of the base layer is metal zinc or zinc alloy, and the material of the modification layer comprises ceramic powder and an electronic conductive material.

The invention discloses organic silicone modified styrene-butadiene latex and a preparation method thereof. By adopting a core-shell emulsion polymerization process, the latex takes deionized water as a dispersion medium, and butadiene and styrene as main monomers, adopts an organic silicone monomer for functional modification, and uses reactive emulsifiers, such as allyl ether sulfonates, acrylamide sulfonates, maleic acid derivatives and the like. The particle size of the latex is 120-150nm; the particle size distribution presents relatively narrow monodispersion; the liquidity is good; the viscosity is appropriate; the latex has very good mechanical stability and chemical stability, remarkable improvements on alkali resistance, water resistance, yellowing resistance and the like, and particularly solves the defects that present acrylate emulsion in the market is not good in alkali resistance or water resistance when used on a textile coating of a fiberglass mesh, the coating yellows easily, and the present acrylate emulsion is sticky when heated and fragile when cooled, therefore, the comprehensive performance of the latex is greatly superior to those of the commonly used acrylics and modified emulsion.

The invention discloses a portable sensing system for early diagnosing liver cancer and functional modification method of the portable sensing system. The system comprises a micro cantilever array sensing unit, a surface modifying layer, an encapsulation shell, a driving module and a digital display interface processing circuit, wherein the micro cantilever array sensing unit is used for converting a mechanical signal of a cantilever into an electric signal and outputting the electric signal to a digital display interface processing circuit; the surface modifying layer grows on the surface of the micro cantilever array sensing unit and is used for functionalizing the surface of the micro cantilever array sensing unit so that the micro cantilever array sensing unit is capable of combining with a liver cancer landmark antigen specificity; the encapsulation shell is used for protecting the micro cantilever array sensing unit and providing a biochemical reaction sample inlet/outlet and a reaction chamber; the driving module is used for providing a resonant drive signal; and the digital display interface processing circuit is used for obtaining and outputting the liver cancer landmark quality according to the variation of resonant frequency of the micro cantilever. According to the system and method provided by the invention, the early screening of the liver cancer is possible, and the important significance is provided for early diagnosing and early treating the liver cancer and improving the survival rate of the liver rate.

The present invention relates to D. melangaster insulin-like genes and methods for identifying insulin-like genes. The methods provide nucleotide sequences of D. melangaster insulin-like genes, amino acid sequences of their encoded proteins, and derivatives (e.g., fragments) and analogs thereof. The invention further relates to fragments (and derivatives and analogs thereof) of insulin-like proteins which comprise one or more domains of an insulin-like protein. Antibodies to an insulin-like protein, and derivatives and analogs thereof, are provided. Methods of production of an insulin-like protein (e.g., by recombinant means), and derivatives and analogs thereof, are provided. Further, methods to identify the biological function of a D. melangaster insulin-like gene are provided, including various methods for the functional modification (e.g., overexpression, underexpression, mutation, knock-out) of one or more genes simultaneously. Still further, methods to identify a D. melangaster gene which modifies the function of, and/or functions in a signaling pathway with an insulin-like gene are provided. The invention further provides uses of Drosophila insulin-like nucliec acids and proteins, e.g., as media additives, and as pesticides.

The invention disclose a method utilizing a nano-channel sensor modified by a nucleic acid probe having a super sandwich structure to high-sensitively and high-specifically detect Zn2+. The method comprises the following steps: (1) preparing a polymer nano channel; (2) designing a nucleic acid probe with a super sandwich structure, wherein the probe has a specific recognition function on Zn2+; (3) carrying out functional modification on the nano channel; (4) carrying out Zn2+ quantitative detection. The invention provides a novel method for detecting specific ions. The detection sensitive of Zn2+ can reach 1 nM, the specificity is high, other ions can be well identified, moreover, the sensor has a stable property, and the repeatability is high.