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Methods for making and using composites, polymer scaffolds, and composite scaffolds

The present invention relates to methods of making and using composites and scaffolds as implantable devices useful for tissue repair, guided tissue regeneration, and tissue engineering. In particular, the present invention relates to methods of making and using compression molded resorbable thermoplastic polymer composites which can be subsequently processed with non-organic solvents to create porous, resorbable thermoplastic polymer scaffolds or composite scaffold with interconnected porosity. Furthermore, these composites or scaffolds can be coated with an organic and / or inorganic material.
Owner:LOREM VASCULAR PTE LTD

Systems and methods for manufacturing liposomes

The present invention provides apparatus and processes for producing liposomes. By providing a buffer solution in a first reservoir, and a lipid solution in a second reservoir, continuously diluting the lipid solution with the buffer solution in a mixing chamber produces a liposome. A therapeutic agent, such as nucleic acid, is included in one of the buffer solution or the lipid solution. Upon mixing a liposome encapsulating the therapeutic product is substantially instantaneously formed. Thereafter the liposome solution formed is immediately diluted with buffer solution to enhance homogeneity and maintain small particle size.
Owner:ARBUTUS BIOPHARMA CORPORAT ION

Controlled architecture ceramic composites by stereolithography

A process for producing a ceramic composite having a porous network. The process includes providing a photocurable ceramic dispersion. The dispersion consists of a photocurable polymer and a ceramic composition. The surface of the dispersion is scanned with a laser to cure the photocurable polymer to produce a photocured polymer / ceramic composition. The photocured composition useful as a polymer / ceramic composite, or the polymer phase can be removed by heating to a first temperature that is sufficient to burn out the photocured polymer. It is then heated to a second temperature that is higher than the first temperature and is sufficient to sinter the ceramic composition to produce a purely ceramic composition having a porous network.Preferably and more specifically, the process uses a stereolithographic technique for laser scanning. The process can form a high quality orthopedic implant that dimensionally matches the bone structure of a patient. The technique relies upon laser photocuring a dense colloidal dispersion into a desired complex three-dimensional shape. The shape is obtained from a CAT scan file of a bone and is rendered into a CAD file that is readable by the stereolithography instrument. Or the shape is obtained directly from a CAD file that is readable by the stereolithography instrument.
Owner:UNITED STATES SURGICAL CORP +2

Customized prosthesis and method of designing and manufacturing a customized prosthesis by utilizing computed tomography data

A method of making an acetabular prosthesis includes acquiring a first set of data defining in three dimensions at least a portion of a bone of a patient. A second set of data is computed based upon the first set of data. The prosthesis is manufactured to include an acetabular cup and an attachment part extending therefrom. The manufacturing step includes the step of forming the attachment part based on the second set of data.
Owner:DEPUY PROD INC

Rapid prototyping and manufacturing system and method

A stereolithography apparatus having a resin vat with resupply containers in one-way flow communication and a leveling container in two-way flow communication, an automatic offload cart to remove and replace build support platforms, an elevator assembly for supporting and releasably retaining a build platform removably attached to the stereolithography apparatus frame such that elevator forks supporting the build platform can be released into the vat and removed from the stereolithography apparatus with the vat, and a recoater assembly and recoater blade for mapping the resin surface in the vat and applying a fresh coating of resin to a cross-section being built in the vat.
Owner:3D SYST INC

Implantable sling having bladder support

ActiveUS20050080317A1Sufficient degree of supportEliminate dependenciesAnti-incontinence devicesWound clampsUrethraCystocele repair
Surgical implants operative to simultaneously function as a pubovaginal sling for the treatment of incontinence and as a support member to effectuate cystocele repair. The implant comprises a first sling portion operative to be positioned beneath the urethra, per conventional pubovaginal sling surgery. The implant further includes a second bladder support portion extending from the sling support portion that is oriented to extend beneath and be surgically attached to a portion of the bladder to thus enable the same to be supported to a degree necessary to effectuate cystocele repair. The implant may be fabricated from a unitary piece of harvested tissue, synthetic material or combinations thereof. Preferably, the sling portion of the implant is fabricated from a synthetic material whereas the bladder support portion of the implant comprises a segment of harvested tissue sewn to the sling portion.
Owner:CALDERA MEDICAL

Rapid manufacturing of porous metal prostheses

An orthopaedic prosthesis and a method for rapidly manufacturing the same are provided. The orthopaedic prosthesis includes a solid bearing layer, a porous bone-ingrowth layer, and an interdigitating layer therebetween. A laser sintering technique is performed to manufacture the orthopaedic prosthesis.
Owner:ZIMMER INC

Rapid prototyping and manufacturing system and method

A stereolithography apparatus having a resin vat with resupply containers in one-way flow communication and a leveling container in two-way flow communication, an automatic offload cart to remove and replace build support platforms, an elevator assembly for supporting and releasably retaining a build platform removably attached to the stereolithography apparatus frame such that elevator forks supporting the build platform can be released into the vat and removed from the stereolithography apparatus with the vat, and a recoater assembly and recoater blade for mapping the resin surface in the vat and applying a fresh coating of resin to a cross-section being built in the vat.
Owner:3D SYST INC

High-resolution rapid manufacturing

The present invention is a method for forming an object, the method comprising jetting a first material to form a plurality of layers that define a support structure increment, and extruding a second material to form a layer of the object. The layer of the object substantially conforms to an interior surface of the support structure increment.
Owner:STRATSYS INC

High-resolution rapid manufacturing

The present invention is a method for forming an object, the method comprising jetting a first material to form a plurality of layers that define a support structure increment, and extruding a second material to form a layer of the object. The layer of the object substantially conforms to an interior surface of the support structure increment.
Owner:STRATSYS INC

Method for quick-speed preparing aerogel by hydro-thermal synthesis at low cost

The invention discloses a method for preparing aerogel materials by combining hydrothermal synthesis technology and sol-gel technology. The prepared aerogel comprises one or more of alumina aerogel, silica aerogel, zirconia aerogel and titania aerogel. The method comprises the following steps: mixing a reactant and a structure-directing agent according to certain proportion, and adding a pH value control agent to adjust the pH value; sealing hydrothermal reaction equipment, heating the mixture to be between 50 and 280 DEG C, making the mixture stand for 0 to 72 hours, raising the temperature to be between 60 and 300 DEG C, and continuously reacting for 0.1 to 72 hours; and cooling gel, taking out the gel, drying the gel and obtaining the aerogel. Compared with the prior art, the method has low reaction temperature and pressure, small equipment investment and simple and controllable technology, reduces potential safety hazards, greatly improves the preparation speed of the aerogel, saves the production cost, and is favorable to realize commercial mass production.
Owner:纳诺科技有限公司 +1

Rapid prototyping and manufacturing system and method

A stereolithography apparatus having a resin vat with computer controlled heating elements responsive to thermistors for controlled preheating of the resin vat, an elevator assembly for supporting and releasably retaining a build platform removably attached to the stereolithography apparatus frame such that elevator forks supporting the build platform can be released into the vat and removed from the stereolithography apparatus with the vat, and a recoater blade that can be removed and accurately installed by hand, thus providing that all wetted components can be quickly and efficiently removed and installed and enabling rapid changeover from spent resin to fresh resin and minimizing apparatus downtime between stereolithography operations.
Owner:3D SYST INC

Integrated Leadframe And Bezel Structure And Device Formed From Same

An integrated leadframe and bezel structure includes a planar carrier frame, a plurality of bonding leads, a die pad region, and a bezel structure. The bezel structure includes a bending portion shaped and disposed to facilitate a portion of said bezel structure being bent out of the plane of said carrier frame. A sensor IC may be secured to the die pad region, and wire bonds made to permit external connection to the sensor IC. The bezel structure includes portions which are bent such that their upper extent is in or above a sensing surface. The assembly is encapsulated, exposing on the top surface part of the bezel portions and the upper surface of the sensor IC, and on the bottom surface the contact pads. Two or more bezel portions may be provided, one or more on each side of the sensor IC.
Owner:APPLE INC

Rapid prototyping and manufacturing system and method

A stereolithography apparatus having a resin vat with resupply containers in one-way flow communication and a leveling container in two-way flow communication, an automatic offload cart to remove and replace build support platforms, an elevator assembly for supporting and releasably retaining a build platform removably attached to the stereolithography apparatus frame such that elevator forks supporting the build platform can be released into the vat and removed from the stereolithography apparatus with the vat, and a recoater assembly and recoater blade for mapping the resin surface in the vat and applying a fresh coating of resin to a cross-section being built in the vat.
Owner:3D SYST INC

Apparatus and Method for Solar Cells with Laser Fired Contacts in Thermally Diffused Doped Regions

This invention relates to an apparatus and a method for solar cells with laser fired contacts in thermally diffused doped regions. The cell includes a doped wafer and a plurality of first highly doped regions having a first conductivity type. The cell also includes a plurality of second highly doped regions having an opposite conductivity type from the first conductivity type and a passivation layer disposed over at least a portion of each the plurality of first highly doped regions and the plurality of second highly doped regions. The cell also includes a network of conductors having a first conductor and a second conductor, and a plurality of contacts electrically connecting the first highly doped regions with the first conductor and electrically connecting the second highly doped regions with the second conductor.
Owner:BP CORP NORTH AMERICA INC

An aerosol generating device and system with improved airflow

There is provided an aerosol generating system comprising: an aerosol-forming article comprising an aerosol-forming substrate and a mouthpiece portion for allowing a user to draw air through the substrate; and an aerosol generating device, the device comprising a housing having proximal and distal ends and comprising at least one external surface and one internal surface, the internal surface defining an open ended cavity at the proximal end of the housing in which the aerosol-forming substrate is received, the cavity having a longitudinal extent between its proximal and distal ends, a heater element within the cavity configured to heat an aerosol-forming substrate received in the cavity, and an air inlet; wherein the system comprises a first air flow channel extending from the air inlet to a distal end of the cavity, wherein the first air flow channel extends between the heater and the external surface of the housing along at least a portion of the longitudinal extent of the cavity, and a second air flow channel extending from the distal end of the cavity to the mouthpiece portion.
Owner:PHILIP MORRIS PROD SA

System, Method and Apparatus for Producing Fire Rated Doors

The present invention provides a system, method and apparatus for producing fire rated doors having added strength, better finishing and low cost manufacturing flexibility. The fire rated doors are made from two panels “sandwiched” together. An optional interior layer (e.g., fire resistant material, lead sheeting, steel or Kevlar) can be added between the door panels for various purposes. Splines, stiles or sticks are inserted in longitudinal channels in the door panels to provide assistance in aligning the door panels and greater hardware holding strength. An intumescent banding material concealed by a banding material around the perimeter of the door seals the door within its frame during a fire. The door design and the automated manufacturing process provide greater design choice, reduced cost and faster fabrication.
Owner:POLYMER WOOD TECH

Droplet Operations Platform

The invention relates to a droplet actuator device and methods for integrated sample preparation and analysis of a biological sample. A droplet actuator device is provided for conducting droplet operations. The droplet actuator device may include a bottom substrate and a top substrate separated from each other to form a gap therebetween; an arrangement of droplet operations electrodes arranged on one or both of the bottom and / or top substrates for conducting droplet operations thereon; a reagent storage layer comprising one or more compartments bound to the top substrate; and one or more openings arranged to provide a fluidic path from the one or more compartments into the gap, upon breach of a breachable seal separating the one or more compartments and openings.
Owner:ADVANCED LIQUID LOGIC

Coatings with cross-linked hydrophilic polymers

The present invention relates to a process for permanently coating the inner surface of columns, capillaries and microchannel systems with hydroxylic polymers, such as polyvinyl alcohol, and to the thus prepared columns, capillaries and microchannel systems and their use.
Owner:AGILENT TECH INC

Multi-beam laser scanning system and method

A multi-beam laser scanning system comprising a laser, a beam splitter, a first scanning unit, a second scanning unit, and a control unit is disclosed herein. The laser is used for generating an initial laser beam. The beam splitter is used for splitting the initial laser beam into a first laser beam and a second laser beam. The first scanning unit is used for deflecting the first laser beam along a desired direction. The second scanning unit is used for deflecting the second laser beam along a desired direction. The control unit is coupled to the first and second scanning units and arranged to output control signals to the first and second scanning units to manufacture an object.
Owner:GENERAL ELECTRIC CO

Method and device for producing a component of a turbomachine

The invention relates to a method for producing a component (10) of a turbomachine, especially a structural part of a turbine or a compressor, the method being a generative production method for the layer-by-layer buildup of the component (10). After production of one or more successive component layers pressure is applied to at least sections of the surface of the most recently produced component layer (12), the pressure being induced by laser or plasma. The invention further relates to a device for producing a component (10) of a turbomachine, especially a structural part of a turbine or a compressor, the device (26) comprising at least one powder feed (28) for the deposition of at least one powder component material (16) onto a component platform, at least one radiation source (14) for a local layer-by-layer fusion or sintering of the component material (16) and at least one laser radiation source (20) or at least one plasma impulse source.
Owner:MTU AERO ENGINES GMBH
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