The invention relates to an
integrated circuit core particle time sequence optimization method and device, equipment and a medium. Analyzing the
time sequence of the
core particle according to the total negative
time sequence margin of all paths generated by the OpenSTA tool on the establishment time, the total negative time sequence margin of all paths on the
retention time, the negative time sequence margin of all paths under the worst establishment time and the negative time sequence margin of all paths under the worst
retention time; when a violation occurs, the preliminary
core particle division scheme is readjusted to determine an iterative division scheme until the time sequence of the core particles meets the requirement; and when the iteration division scheme meets the time
sequence optimization requirement, recording and storing the current iteration division scheme, and continuing to perform regular division on the
integrated circuit modules at the same level until all the preliminary core particle division schemes at the level are completely traversed. The design period can be greatly shortened, and
automation and flexibility can be remarkably improved.