The invention relates to a multi-objective optimization data transmission method based on a mobile node locus. According to the method, movement statistical information of mobile nodes and locus information of a large number of real mobile nodes are used for obtaining auxiliary data and transmitting corresponding data, a transmission problem of data packages is mapped to be the multi-objective Markov decision-making process, the Markov decision-making process is solved, so that objective functions of multiple route indexes are optimized, finally the data packages are transmitted according to the optimal forwarding policy obtained through a solution, and therefore an efficient wireless self-organizing network data transmission method from the mobile nodes to the mobile nodes is achieved, wherein the method is also suitable for data transmission from the mobile nodes to a base station and from the base station to the mobile nodes. According to the multi-objective optimization data transmission method, application modes and fields are wide, multiple data transmission indexes are optimized, so that the delivery rate is increased, the data transmission efficiency is improved, the data transmission error rate and consumed network resources are reduced, and therefore the better communication effect is achieved.