308 results about "Residual solvent" patented technology

The invention relates to the technical field of toughening agents, in particular to a hyperbranched epoxy resin modified MBS toughening agent and a preparation method thereof.The preparation method comprises the following steps that (S1) a cyclotriazine compound, polyglycidyl ether and a catalyst are added into an organic solvent to be mixed, a reaction is conducted for 8-72 h at the temperature of 30-150 DEG C under the protection of nitrogen, and after the reaction is completed, alcohol precipitation and drying are conducted to obtain a hyperbranched epoxy resin modified MBS toughening agent; the hyperbranched epoxy resin is obtained; (S2) adding the hyperbranched epoxy resin into the solvent A, uniformly mixing, then adding MBS resin, stirring for 0.5-1 hour at a high speed under the condition of room temperature, then heating to 70-110 DEG C, stirring for 0.5-1 hour, and removing the residual solvent to obtain the hyperbranched epoxy resin modified MBS toughening agent, and by utilizing the hyperbranched characteristic of the resin, enabling the modified MBS toughening agent to be used for preparing the hyperbranched epoxy resin modified MBS toughening agent. The toughening effect can be achieved by adding a small amount of the toughening agent into common epoxy resin.

The invention discloses a post-treatment system and process for PBF printing plastic parts, and the post-treatment system comprises a solvent storage bottle, a part treatment assembly and a solvent recovery assembly; a solvent is stored in the solvent storage bottle; the part processing assembly is used for carrying out fairing treatment on the PBF printing plastic part; the solvent recovery assembly is used for recovering the vaporized solvent in the part treatment assembly and re-liquefying and storing the vaporized solvent; the output end of the solvent storage bottle is connected with the input end of a solvent cabin of the part treatment assembly through a peristaltic pump, and the part treatment assembly is connected with the solvent recovery assembly through a recovery valve. According to the principle that the solvent is rapidly vaporized under the pressure difference, then uniformly reaches any surface position of the workpiece and is condensed and liquefied again, the surface defects of the workpiece are gradually dissolved and leveled under the action of the solvent, then the solvent steam is liquefied and recovered again, and the residual solvent on the surface of the workpiece is removed. The common surface roughness problem of the 3D printing plastic part can be effectively improved, and the appearance quality of the part is improved.

The invention relates to the technical field of membrane separation, in particular to a composite forward osmosis membrane based on mussel bionic interface enhancement and a preparation method thereof. The preparation method comprises the following steps: immersing a base material in a dopamine hydrochloride solution for oscillation reaction to obtain a modified base material; the surface of the modified base material is coated with a membrane casting solution in a blade coating mode, then phase inversion is carried out, the residual solvent is removed, then airing is carried out, and the composite forward osmosis membrane based on mussel bionic interface enhancement is obtained. By introducing the mussel bionic polydopamine intermediate layer, the long-standing technical contradictions of poor interfacial compatibility and weak binding force between the hydrophobic substrate and the hydrophilic separation layer are ingeniously solved, and the internal concentration polarization effect is remarkably inhibited. The prepared composite membrane has the advantages of high water flux, low salt reverse flux, stable structure and the like, and has wide application prospects in the fields of water treatment and substance separation.

The invention belongs to the technical field of pharmaceutical analysis, and particularly relates to a method for determining a residual solvent in LXH-2103 by headspace gas chromatography. The determination method comprises the following steps: preparing a blank solution, a reference substance solution and a sample solution, respectively injecting the blank solution, the reference substance solution and the sample solution into a headspace for balancing, injecting the solutions into a gas chromatograph in a headspace sample injection manner, recording a chromatogram, and calculating the content according to a peak area by an external standard method; the residual solvent is absolute methanol, absolute ethyl alcohol, isopropanol, dichloromethane and methylbenzene. The method for determining the residual solvents in the LXH-2103 by using the headspace gas chromatography, provided by the invention, is high in sensitivity, good in repeatability and high in accuracy, and can be used for simultaneously detecting various residual solvents in the LXH-2103, so that the quality of the LXH-2103 is ensured, and the safety of clinical medication is improved.

The invention discloses a preparation method of a PA6 / PEO micro-nanofiber air filtering membrane with a bent form, which comprises the following steps: (1) weighing PA6 particles and PEO powder with a certain mass, and dissolving in a formic acid solution with the mass fraction of 88% to obtain a mixed solution; (2) stirring the mixed solution to obtain a PA6 / PEO spinning solution; (3) forming a fiber membrane under a room-temperature dry condition through a gas jet spinning machine; (4) drying overnight at 60 DEG C to remove the residual solvent; (5) performing heat treatment in a drying oven, and (6) at normal temperature, placing the fiber membrane subjected to heat treatment in a container, and adding deionized water to immerse the fiber membrane; (7) heating the container in a water bath, and repeating the water bath treatment twice; and (8) immediately taking out the sample after the reaction is finished, and performing vacuum drying treatment. According to the invention, oily and salty ultrafine particles can be efficiently filtered at the same time, and the technical problem that effective filtration of fine oily and salty particles is difficult to realize in the prior art is solved by optimizing the structural characteristics of the fiber membrane.

The invention belongs to the technical field of alkaline electrolyzed water, and relates to a preparation method of an LDH / PSF / PP composite anion exchange membrane, which comprises the following steps: step 1, uniformly dispersing PSF polymer molecules in a polar organic solution to form a PSF polymer solution; step 2, preparing LDH with a high specific surface area, and uniformly dispersing the LDH into the PSF polymer solution to prepare a membrane casting solution; 3, blade-coating the prepared membrane casting solution on a PP support net to form a serous membrane, and then transferring the composite membrane to a drying oven for a pre-evaporation process; step 4, transferring the pre-evaporated composite membrane into a coagulating bath for phase inversion, and curing the PSF in the coagulating bath due to solvent precipitation so as to form a solid composite membrane; and step 5, soaking the prepared solid composite membrane in deionized water to remove the residual solvent. The preparation method of the LDH / PSF / PP composite anion exchange membrane has the advantages of low surface resistance, high gas barrier property, high mechanical strength and capability of realizing large-scale preparation, and is a preparation method of the LDH / PSF / PP composite anion exchange membrane with relatively high innovativeness.

The invention discloses a preparation method and application of a polymer membrane based on solvent in-situ functionalization enhancement. The method comprises the following steps: dissolving a polymer raw material by adopting a polymerizable solvent to form a homogeneous membrane casting solution; then synchronously carrying out ultraviolet light induced polymerization on the residual solvent in the membrane in the membrane casting liquid phase separation forming process by utilizing a constant-temperature circulating coagulating bath carrying an ultraviolet light illumination system; performing drying treatment to obtain a flat plate / hollow fiber composite membrane; the method is applied to the aspects of seawater desalination, wastewater treatment, food processing, biological medicine, energy chemical industry and the like. By utilizing dual functions of the solvent, polymerized solvent molecules and macromolecular chains form a stable cross-linked interpenetrating network structure, functional design of the membrane is realized through customizability of the solvent, functionalization enhancement of the membrane is realized while the process is simplified, ultraviolet polymerization synchronously optimizes phase separation kinetics, and the performance of the membrane is improved. Uniform surface pore size distribution and efficient mass transfer channels are formed, and the advantages of high efficiency and customizability are shown.

A method for purifying sodium fluoride by using complexing crystallization belongs to the technical field of sodium fluoride purification, and comprises the following steps: preparing a dissolving solution; complexing the dissolving solution with a complexing agent to obtain a complexing solution; the complexing solution is pumped into membrane separators, the complexing solution passes through the first membrane separator, a mixed solution of complexing precipitation and a complexing agent is filtered and intercepted through a tube pass of the first membrane separator, and a filtrate enters other membrane separators through a shell pass of the first membrane separator to be subjected to multi-stage separation to obtain a membrane separation solution; performing pure crystallization on the membrane separation liquid; and centrifugally separating to obtain purified sodium fluoride, and drying the purified sodium fluoride to remove the residual solvent, thereby obtaining the high-purity sodium fluoride. According to the method, the content of cation impurities and the content of anion impurities in sodium fluoride are effectively reduced at the same time, high-purity sodium fluoride is obtained through a pure crystallization method, the centrifugal separation liquid, the complexing agent and the alcohol crystallizing agent can be recycled, and the purposes of high efficiency, environment friendliness and low cost of purification are achieved.

The invention relates to the technical field of liquid chromatographic analysis, and discloses a data acquisition method and system of a liquid chromatograph. The method comprises the following steps: extracting chromatograms without solvent residues and with known solvent residues from a historical database, and training by using a self-encoding neural network and a convolutional neural network to generate a baseline reference model and a ghost peak early warning model; obtaining solvent parameters of the previous analysis method, and calculating the residual solvent concentration through residual solvent information; inputting the residual solvent concentration into the baseline reference model and the ghost peak early warning model, and calculating to obtain a baseline drift prediction correction value and a ghost peak prediction risk area; pre-correcting the chromatographic signal acquired in real time to obtain a purified chromatographic signal; performing qualitative and quantitative analysis on the purification signal according to dynamic allocation resources of the ghost peak risk area to generate final chromatographic data; the data interference of the mobile phase residue is effectively eliminated, and the accuracy of data acquisition is improved.

The invention relates to a method for detecting residual solvent benzene in a ziprasidone hydrochloride bulk drug. According to the detection method, dimethyl sulfoxide is used as a diluent, a 2.8 mol / L potassium hydroxide solution is used as a cosolvent, and a dimethyl sulfoxide solution of high-concentration ziprasidone hydrochloride can be completely dissolved under a high-temperature heating condition, so that the sensitivity of benzene meets the requirement; and detecting the benzene in the ziprasidone hydrochloride bulk drug by using a gas chromatograph (GC-FID headspace sampling) connected with a hydrogen flame ionization detector. The detection method can be used for quantitatively detecting benzene higher than 0.4 ppm in ziprasidone hydrochloride bulk drugs. The method is high in sensitivity and practicability, and the detection process is simple and rapid.

The utility model relates to a washing, dewatering and drying device for resin particles. The washing, dewatering and drying device comprises a barrel, a filtering barrel, a spraying mechanism and a drying mechanism, and the barrel is provided with a feeding port and a drainage port; the filtering barrel is arranged in the barrel body so as to divide the interior of the barrel body into a material cavity located on the side, close to the feeding opening, of the filtering barrel and a water drainage cavity located on the side, close to the water drainage opening, of the filtering barrel; the spraying mechanism is arranged above the filtering barrel, and the drying mechanism is communicated with the material chamber. Resin particles can fall onto the filtering barrel through the feeding hole to realize dehydration; the spraying mechanism can be used for cleaning resin particles on the filtering barrel, residual solvents in the resin particles can be washed and leached out, and sewage can flow into the drainage cavity through the filtering holes and then is discharged to the outside through the drainage opening; the drying mechanism can dry resin particles in the material cavity, dewatering, cleaning and drying can be integrated, the problem that the resin particles are seriously rubbed can be avoided, the structure is simple, and the production efficiency can be improved.

The invention discloses a multilayer microencapsulated small molecule peptide liposome as well as a preparation method and application thereof. According to the invention, a'liposome-wall material 'double-embedding structure is formed by optimizing the phospholipid purity and compounding the hydrophilic wall material and the stabilizer, and a high-pressure homogenization and low-temperature spray drying combined process is adopted, so that the preparation process is green and environment-friendly. The obtained lipidosome has the characteristics of good fluidity, excellent sensory characteristics, high stability and the like, the solvent residue is far lower than the industrial standard, and the lipidosome can be widely applied to dosage forms such as tablets, capsules, solid beverages and the like. According to the technology, the production process is simplified, the use of toxic solvents is avoided, the bioavailability of the small molecule peptide is remarkably improved, and the problems of stability and production cost in industrial application are solved.

The invention belongs to the field of high polymer material synthesis, and provides a method for preparing polyphenylene sulfide from high-purity p-dichlorobenzene, which adopts the whole process design of pre-construction of a composite sulfur source intermediate, regulation and control of an end group controllable oligomerization polyphenylene sulfide intermediate, segmented polymerization of the high-purity p-dichlorobenzene and precise dehydration-washing-drying. The ultra-low impurity level of 0.05-0.25 wt% of burning residues of the polyphenylene sulfide product, the sodium ion content of 10-200 mg / kg and the chloride ion content of 10-500 mg / kg is achieved, and meanwhile the high-performance stability of the melting point of 270-300 DEG C, the gel fraction of 92-99 wt% and the water content of 0.01-0.20 wt% is kept. The problems of deep removal of inorganic ions and ash content, balance of gel fraction and processability and control of residual solvents in the traditional polyphenylene sulfide preparation process are solved, and the method has wide application value in the fields of high-performance engineering plastics, special fibers, electronic packaging materials and the like.

To provide a gravure or flexographic ink that is superior in temporal stability, blocking resistance, high-temperature laminate strength, and low residual solvent level.SOLUTION: A gravure or flexographic ink includes a urethane resin (A), wherein the breaking stress of the urethane resin (A), measured under the conditions defined below, is 10 MPa or more, and the viscosity of the urethane resin (A) at a liquid temperature of 25°C and a solid content of 30 mass%, measured in accordance with JIS K 7117-1, is 800 mPa s or more. (Stress measurement conditions) Tensile speed: 50 mm / min, Temperature: 25°C, Sample shape: thickness 0.3 mm, width 5 mm, length 20 mm.SELECTED DRAWING: None

The invention relates to the field of PCB transfer, in particular to a transfer trolley for PCB production and processing. According to the transfer trolley, a closed space is formed by a sleeve shell and an electric control lifting cabin and used for preventing harmful chemical gas from leaking outwards, hot air flow is conveyed to all layers of PCBs through an air heater so as to accelerate volatilization of residual solvents and the harmful chemical gas, then volatile matter is pumped to an activated carbon layer through an exhaust fan to be adsorbed, and through the process, the residual solvents and the harmful chemical gas can be recycled. According to the PCB stacking device, the PCB residual solvent can be rapidly volatilized and harmful gas can be collected and treated synchronously in the transferring process, and in addition, the stacking operation of all PCBs in the electric control lifting cabin can be rapidly completed by pulling open the side supporting plates between the C-shaped inserting rails; the technical problem that each PCB transfer trolley needs to be parked for a long time to wait for a PCB to wait for volatilization of a residual solvent, and the use efficiency of the PCB transfer trolley is seriously affected is solved.

The invention discloses a health food quality safety tracing system based on a block chain. According to the system, an optimization model taking health food quality risk assessment as a target is constructed; selecting the total number of bacterial colonies, the number of pathogenic bacteria, solvent residues, water activity, temperature, air pressure, granularity, mixing uniformity, effective component quantification, dissolution rate, residual oxygen amount and the like as core parameters, and constructing an optimized objective function; in addition, the system monitors and adjusts key parameters such as the temperature, the air pressure, the granularity and the residual oxygen content of the health-care food in real time through the AI driving module, and the food safety coefficient is improved; according to the invention, the conversion from passive supervision to active prevention is realized, the food qualification rate and the resource utilization rate are improved, and the method can be used for links of food production, transportation, sales and the like.

The invention discloses a polyolefin graft modification method based on coating and photochemical reaction, which comprises the following steps: step 1, raw material preparation: mixing 20-50 parts by weight of glycidyl methacrylate (GMA), 1-5 parts by weight of benzophenone (BP) and 1-2 parts by weight of triethylamine (TEA), and uniformly stirring to obtain a mixed solution; 2, coating: coating the surface of a polyolefin film with the mixed solution obtained in the step 1, wherein the coating weight is 1g / m < 2 >-3g / m < 2 >; the method has the beneficial effects that a peroxide initiator is not needed, the reaction is initiated by ultraviolet light, the reaction condition is mild, polyolefin degradation and side reaction are reduced, and the grafting rate is greater than 3.5%; ethyl acetate and other low-toxicity solvents are adopted, residual solvents can be removed through oven treatment, and the environment-friendly requirement is met; active groups such as an epoxy group are introduced into a grafted product, so that the compatibility with a polar material is remarkably improved, and the breaking strength is improved by more than 50% compared with that of common PP; the polyolefine can be used as an interface compatibilizer, a macromolecular coupling agent and the like, and the application of the polyolefine in the high-end field is expanded.

The invention provides a process flow for producing humic acid, which comprises the following steps: S1, providing raw material coal, and extracting the raw material coal to form a reaction material which is a humic acid extract; s2, carrying out solid-liquid separation on the reaction material through a horizontal screw centrifuge, so that the reaction material is divided into material slag and primary clarified liquor; s3, water is added into the material residues for washing, and a mixture of the material residues and the water is formed; and S4, separating the mixture through a horizontal screw centrifuge to form a crude material and a secondary clarified liquid. According to the technological process for producing the humic acid, by adding the horizontal screw centrifuge, efficient separation of solid material residues and clarified liquor in the humic acid extract is achieved, the yield and purity of the product are improved, and due to the fact that the material residues obtained after solid-liquid separation possibly contain residual solvents or impurities, the horizontal screw centrifuge is used for dehydration of the washed material residues, and the product yield is improved. The secondary clarified liquor capable of being prepared into a refined product is separated, and the quality and grade of the refined product are improved.

The invention relates to the technical field of stealth material preparation, in particular to a protective coating with a stealth function and a preparation method thereof.The preparation method of the protective coating with the stealth function comprises the steps that 1, matrix resin, a flame retardant, fiber filler, auxiliaries and part of solvent are premixed and dispersed, and a component A is obtained; (2) premixing and dispersing the stealth filler, the curing agent and the residual solvent to obtain a component B; and (3) uniformly mixing the component A and the component B to obtain the protective coating with the stealth function. The prepared protective coating with the stealth function is excellent in performance, and through the multiphase collaborative design of the matrix resin, the stealth filler and the flame retardant, the protective coating has excellent stealth performance and long-acting environmental stability.

The objective is to provide 5-aminolevulinic acid or its salts and a method for producing the same, which have fewer impurities and residual solvents and suppressed discoloration compared to conventional methods. The objective is to provide 5-aminolevulinic acid or its salts, wherein, based on peak area obtained by HPLC analysis, the ratio of the content of individual impurities to the content of 5-aminolevulinic acid or its salt is 0.0007 or less, and the sum of the ratios of the content of individual impurities to the content of 5-aminolevulinic acid or its salt is 0.0016 or less.

The invention discloses a crystal form and a preparation method of Alalistrum hydrochloride, the crystal form comprises a crystal form Form3, a crystal form 4 and a crystal form Form11, Alalistrum hydrochloride solids Form3 (methanol-water composite solvate), Form4 (hydrate) and Form11 can be obtained by mixing and dissolving Alalistrum hydrochloride solids and an organic solvent, and then adopting the modes of crystallization, crystal mush and volatilizing, and the Alalistrum hydrochloride solids Form3 (methanol-water composite solvate), Form4 (hydrate) and Form11 can be obtained by using the crystal form of Alalistrum hydrochloride and the preparation method of the crystal form of Alalistrum hydrochloride and the preparation method of the crystal form of Alalistrum hydrochloride. The preparation method disclosed by the invention is simple in process, strong in operability, high in yield, high in purity and good in crystallinity, and the crystal form disclosed by the invention is high in solubility, few in residual solvent and good in solid property and meets the medicinal development standard.

The utility model discloses a polymerization system for dehydration condensation reaction, which belongs to the technical field of polymer production and comprises a polymerization reaction kettle, a through hole is arranged at the top of the polymerization reaction kettle, a tower column is vertically arranged on the through hole, the tower column comprises a plurality of tower sections which are sequentially communicated from top to bottom, and fillers are arranged in the tower sections. A tower cap is arranged at the top end of the tower section located at the uppermost end of the tower column, a cooling jacket and a thermometer are arranged on the tower cap, a gas phase outlet is formed in the upper portion of the tower cap and connected with a water removal tank, a gas outlet in the top of the water removal tank is connected with a recovery device, and a vacuum pump is connected to the tail end of the recovery device in the running direction of the recovery device; the vacuum pump is connected with a PLC. By utilizing the tower column, a solvent and a monomer with high boiling points are condensed, and water and impurities with lower boiling points leave the tower column, so that the raw material waste is reduced while the reaction is promoted; a water removal tank is arranged to absorb moisture in gas, so that the moisture in the gas is prevented from condensing when residual solvents and monomers are condensed in the recovery device, and the separation effect is not influenced.

The present invention addresses the problem of providing a gas purification system that removes trace impurities in a gas. [Solution] A gas purification system (1) is provided with: a system unit (11) provided with a gas source unit (111) having a storage container, a purifier unit (113) for removing a residual solvent from a gas, and a purification unit (112) for controlling the purification operation in the purifier unit (113); an evaluation means (13) for evaluating the state of at least the purifier means (113) from at least one of the system parameters (1100), the system monitoring data (1200), and the user parameters (1300) by means of the evaluation conditions of the rule base and / or the machine learning model (131); and a control means (15) provided with a purifier control means (152) that controls the purifier means (113) on the basis of the data evaluated by the evaluation means (13).

The invention belongs to the technical field of pharmaceutical analysis, and particularly relates to a method for determining a residual solvent in LXH-1211 by adopting headspace gas chromatography. Preparing a reference solution and a test solution of the LXH-1211, respectively carrying out headspace equilibrium on the blank solution, the reference solution and the test solution, injecting the solutions into a gas chromatograph in a headspace sample injection manner, recording a chromatogram, and calculating the content of the residual solvent in the test solution by peak area according to an external standard method; wherein the residual solvent is one or more of methanol, ethanol, dichloromethane, dioxane, N, N-diisopropylethylamine or N, N-dimethylformamide. The method is high in sensitivity, good in repeatability and high in accuracy, and can be used for simultaneously detecting the contents of various residual solvents in the LXH-1211, so that the quality of the LXH-1211 is ensured, and the safety of clinical medication is improved.

The invention relates to the technical field of laser welding, in particular to self-adaptive laser welding equipment. According to the technical scheme, the device comprises a machining table, a transverse guide rail is fixedly connected to the top end of the machining table, and an adjusting frame is installed at the top of the transverse guide rail. By arranging a scraping structure, multiple sets of scraping blocks can be driven to rotate through rotation of a cleaning disc, and impurities on the surface of a metal plate are scraped through waterproof abrasive paper arranged on the scraping blocks; by arranging the softening structure, a small amount of solvent can be quantitatively added to the metal plate to soften impurities such as oil stains on the metal plate, the softening efficiency is improved by cooperating with the solvent adsorption of the erasing block, and by arranging the erasing structure, the residual solvent and impurities on the surface of the metal plate can be cleaned, so that the surface of the metal plate is kept clean and tidy; and the problem that oil stains or oxidation films on the surfaces of the metal plates can generate adverse effects on welding is solved.

This application discloses a novel tail gas absorption and desorption system for soybean oil extraction, comprising: an identification module, an absorption module, a magnetic field module, and a feeding module. The identification module is used to identify hazardous substances, and the specific identification steps are as follows: real-time acquisition of risk data, calculation of migration risk index based on risk data, and adjustment of absorption parameters according to migration risk index; acquisition of pressure data and valve status data of the absorption tower in the absorption module, calculation of escape risk index, and classification of escape risk level according to escape index; monitoring of residual solvent concentration in tail gas, adjustment of spray volume and centrifuge status according to residual solvent concentration, and automatic switching of treatment scheme according to the magnitude of migration risk index through a graded treatment mechanism, thereby achieving effective control and removal of hazardous substances in degummed oil, reducing hazardous substance residue, and improving the quality and safety of degummed oil.

The invention provides a preparation method of an organic-inorganic composite solid electrolyte membrane, which comprises the following steps: A) heating and melting an organic solid electrolyte, an inorganic solid electrolyte and a lithium salt to obtain slurry; and B) coating the surface of a substrate with the slurry, cooling, drying and stripping to obtain the organic-inorganic composite solid electrolyte membrane. According to the method for preparing the organic-inorganic composite solid electrolyte membrane in the solvent-free manner, the composite solid electrolyte membrane is prepared under the solvent-free condition, so that the problem of dependence on the solvent is solved, and the adverse effect of the existence of the residual solvent on the stability of the electrolyte is avoided. Meanwhile, the obvious negative effects of evaporation of toxic organic solvents on the environment and personal health are reduced. Compared with a single-phase electrolyte, the composite solid electrolyte membrane prepared by the invention has more excellent electrochemical performance.

The present invention provides a method for preparing spermidine, which relates to the technical field of organic synthesis. The method for preparing spermidine comprises: condensing 3-chloropropylamine hydrochloride and triphenylmethane to obtain 3-chloro-N-tritylpropylamine; condensing 3-chloro-N-tritylpropylamine and 1,4-butanediamine to obtain N 1 ‑(3‑(tritylamino)propyl)butane‑1,4‑diamine; N 1 The trityl group is removed from 1,4-(3-(tritylamino)propyl)butane to obtain spermidine hydrochloride; and spermidine hydrochloride is liberated in the presence of a base to obtain spermidine. The preparation method of the present invention can achieve a high yield and purity in a relatively short reaction period, avoids the problems of a high proportion of by-products, high purification difficulty, and residual solvent, improves the reaction efficiency, and has mild reaction conditions, simple production equipment, and is more energy-saving and environmentally friendly while being convenient for industrialized amplification production.

The invention discloses a high-strength sealing material for vehicles as well as a preparation method and application thereof, and belongs to the technical field of high polymer materials. The sealing material is prepared by the following steps: mixing polytetrahydrofuran ether glycol and hydroxyl-terminated polydimethylsiloxane, carrying out vacuum dehydration, cooling, adding diphenylmethane diisocyanate under the protection of nitrogen, adding surface modified nano mica sheets, cellulose nanocrystals and part of a solvent after the reaction is finished, uniformly mixing, and carrying out vacuum drying to obtain the sealing material. Then adding an ultraviolet absorbent, an antioxidant and the residual solvent, and mixing to obtain a functional polyurethane prepolymer mixture; dissolving a chain extender, an organic bismuth catalyst and an accelerant in an ethyl acetate solvent to obtain a curing agent mixed solution; and mixing the functional polyurethane prepolymer mixture with the curing agent mixed solution to obtain the functional polyurethane curing agent. The flexible siloxane chain segment and the modified filler are embedded into the polyurethane matrix, so that the material has excellent hydrophobicity, toughness, mechanical strength and sealing performance.