452 results about "Soft gel capsule" patented technology

The present invention discloses automated soft capsule production equipment and a speed regulation method, relating to the field of food and pharmaceutical equipment manufacturing, and is designed to achieve automated soft capsule production. The automated soft capsule production equipment includes an electronic control system, a liquid infusion system, a gelatin strip conveyor system, and a soft capsule pressing and molding system. The electronic control system is connected to the liquid infusion system, the gelatin strip conveyor system, and the soft capsule pressing and molding system, respectively. The gelatin strip conveyor system includes a thickness sensor for measuring the thickness of the conveyed gelatin strip and transmitting a measurement signal to the electronic control system. The gelatin strip conveyor system also includes an angle sensor assembly for measuring the tightness of the conveyed gelatin strip and transmitting a measurement signal to the electronic control system. The electronic control system receives and processes the measurement signal and transmits a control signal to a motor in the gelatin strip conveyor system to adjust the thickness or tightness of the gelatin strip. The liquid infusion system automatically closes and opens the infusion switch via the electronic control system, and the soft capsule pressing and molding system automatically controls the mold compression or release via the electronic control system.

The invention discloses a coenzyme Q10 soft capsule appearance defect detection method based on image recognition, relates to the technical field of capsule detection, and solves the problem that the reliability and pertinence of a detection result are insufficient due to the fact that different types of defects such as size deviation and breakage wrinkles cannot be effectively recognized. According to the method, the standard image and the to-be-analyzed image set are determined from a large number of images, and then the image with the most significant difference between the to-be-analyzed features and the focus is selected for ellipse perimeter comparison; according to the mode, the analysis range can be efficiently narrowed, the area where wrinkles, damage or abnormal sizes possibly exist can be accurately positioned, and the pertinence and efficiency of defect analysis are improved.

The invention discloses a soft capsule dissolution detection device with a self-cleaning function, the detection device comprises a tank body, an outer frame, an evaluation mechanism, a stirring mechanism, a cleaning mechanism, an aeration mechanism and a detection mechanism, the evaluation mechanism comprises an upper sample frame, the stirring mechanism comprises a lock pin disc, a first side frame and a layering mechanism, and the upper sample frame is fixedly connected with the lock pin disc; the layering mechanism is connected with the detection mechanism through a pipeline, the tank body is provided with an upper edge and aeration holes, the cleaning mechanism comprises an outer concave ring and a third motor, the outer frame is fixedly connected with the tank body, the aeration mechanism and the detection mechanism, the aeration holes are fixedly connected with the aeration mechanism, the first side frame and the third motor are fixedly connected with the upper edge, and the outer concave ring is rotationally connected with the upper edge; the invention relates to the technical field of capsule detection devices, samples of different prescriptions and processes can be distinguished and evaluated, the capsule content precipitation condition fits the reality through the simulated stomach bag wriggling effect, and rapid self-cleaning can be achieved.

The invention discloses an automatic mold alignment device and method for a rolling model type soft capsule pelleting machine and the soft capsule pelleting machine, relates to the field of manufacturing of food and medicine equipment, and aims to realize automation of a soft capsule production link. According to the automatic mold alignment scheme of the rolling model soft capsule pelleting machine based on sensor detection, the sensor is used for detecting and recognizing the zero position phase difference of the two mold rollers, the position information is transmitted to the control system, and the control system automatically adjusts the relative positions of the two mold rollers, so that the automatic alignment of the two mold rollers is achieved. Therefore, the purpose of automatic alignment of the mold is achieved. According to the invention, the defects of the traditional manual alignment technology are overcome, and the quality and efficiency of soft capsule production are improved. Various sensor scheme selections are provided, including the laser displacement sensor, the contact type displacement sensor and the industrial camera, the appropriate scheme can be selected according to the actual demand, and remarkable economic benefits and social benefits are achieved.

The invention discloses self-sterilization type packaging equipment for soft capsule production, and relates to the technical field of soft capsule packaging equipment, the self-sterilization type packaging equipment for soft capsule production comprises a cleaning mechanism arranged on a first fixing plate, the cleaning mechanism comprises a first connecting plate fixedly connected with the first fixing plate, and circular plates are rotatably arranged on the first connecting plate at equal intervals; a first belt wheel is fixedly arranged on each round plate. According to the soft capsule cleaning device, the cleaning mechanism is arranged, soft capsules subjected to particle separation are conveyed in a limiting channel through a cleaning roller and rotate at the same time, and therefore the surfaces of the soft capsules are wiped through soft cleaning fabric on the cleaning roller; the oil stain on each soft capsule is erased, and the soft capsule surface which is partially stained with leaked liquid of the damaged soft capsule is erased, so that the quality of the soft capsule is prevented from being influenced by the leaked liquid medicine of the damaged soft capsule, the quality of the soft capsule during bottling is ensured, and the influence of the leaked liquid medicine of the damaged soft capsule is avoided.

The invention discloses a calcium liposome for promoting bone health as well as a preparation method and application thereof. The calcium liposome is prepared from the following components in parts by weight: 3 to 7 parts of phospholipid composition, 0.1 to 0.35 part of phytosterol, 1 to 5 parts of insoluble calcium, 1 to 7.5 parts of protein and 0.1 to 1 part of modifier, wherein the phospholipid composition consists of egg yolk lecithin, phosphatidylinositol and distearoyl phosphatidylcholine, and the mass ratio of the egg yolk lecithin to the phosphatidylinositol to the distearoyl phosphatidylcholine is (8-12): (7-11): ( The specific phospholipid composition obtained through screening is combined with phytosterol to serve as a membrane material to wrap a compound of insoluble calcium and protein, so that the dispersity and the stability of the prepared calcium liposome are obviously improved, when the calcium liposome is applied to preparation of calcium soft capsules, the oil leakage phenomenon is obviously reduced, meanwhile, the absorption of an organism to calcium is also enhanced, and the bioavailability of the calcium soft capsules is improved. Particularly, the bone mineral density and the bone calcium content of an organism are obviously increased, healthy development of bones is promoted, and the difficulty and the pain point of insoluble calcium applied to the fields of functional foods, health care products, biological medicines and the like are effectively solved.

The utility model discloses a pill airing tray for soft capsule production, which comprises a tray body, two mounting plates are fixedly mounted on one side of the tray body, a screw rod is movably mounted on the inner sides of the two mounting plates through bearings, a threaded hoop is in threaded connection with the outer side of the screw rod, a support is fixedly mounted on the outer side of the threaded hoop, a motor is fixedly mounted at one end of the screw rod, and the motor is fixedly mounted on the other end of the screw rod. A sliding hoop is fixedly mounted at the bottom of the other end of the support, a sliding rod movably sleeves the inner side of the sliding hoop, a mounting pipe is arranged at the top of the support, the bottom of the mounting pipe communicates with a plurality of flow guide pipes, and a flow guide cone is fixedly mounted in the mounting pipe. Through the arrangement of the LED lamp strip, the LED lamp strip illuminates the oil paper and the soft capsule in the inspection process, whether the oil stain and liquid seepage phenomena occur or not is inspected through uniform illumination, observation is convenient, inspection stability is improved, and inconvenience of manual lighting is improved.

The invention relates to the technical field of eicosapentaenoic acid ethyl ester soft capsules, and discloses a composition containing eicosapentaenoic acid ethyl ester, a soft capsule type preparation, a preparation process and application, eicosapentaenoic acid ethyl ester compounded with various antioxidant auxiliary material components is used as a content, gelatin and Arabic gum are used as wall materials, and the soft capsule type preparation is prepared by compounding the eicosapentaenoic acid ethyl ester and the soft capsule type preparation. A safe and non-toxic polyhedral oligomeric silsesquioxane (POSS) framework compound which is independently researched and synthesized and has a salicylaldehyde group functional group is used as a curing agent, and safe and non-toxic titanium dioxide which is independently researched and synthesized and has the surface modified with the salicylaldehyde group functional group is used as an opacifying agent; and preparing the ethyl eicosapentaenoate soft capsule preparation by adopting a complex coacervation method. The eicosapentaenoic acid ethyl ester soft capsule type preparation prepared by the invention not only has excellent stability under high-temperature and high-humidity conditions, but also has the peroxide value of eicosapentaenoic acid ethyl ester as low as 1.02 meq / kg and the content of eicosapentaenoic acid ethyl ester as high as 98.79%.

The invention relates to the technical field of computer vision, in particular to a method for quickly identifying apparent defects of fish oil soft capsules. The method comprises the following steps: acquiring a reference region in a fish oil soft capsule image to be identified; obtaining a seed point in the reference area and a corresponding growth threshold value, carrying out area growth, and obtaining all foreign matter reference points in the reference area; acquiring an overlapping coefficient of a non-foreign matter reference point in the reference area, acquiring a new seed point and a corresponding new growth threshold when the overlapping coefficient of the non-foreign matter reference point is greater than a preset overlapping coefficient threshold, performing area growth, and acquiring a new foreign matter reference point; all the foreign matter reference points and the new foreign matter reference points in the reference area form a foreign matter area of the reference area, the foreign matter area of the area where each capsule is located in the gray level image is obtained, and defect recognition is conducted on the fish oil soft capsule image. According to the invention, the complete foreign matter area can be rapidly obtained, and the apparent defect identification of the fish oil soft capsule is more accurate.

The utility model provides a microcapsule preparation device and relates to the technical field of seasoning preparation. The microcapsule preparation device comprises a base, the top of the base is provided with a feeding hopper, the interior of the feeding hopper is rotationally connected with grinding rollers which are symmetrically distributed in pairs, the interior of the base is movably provided with a collecting box, the inner wall of the bottom end of the base is provided with a filter screen, and the top of the filter screen is movably provided with a scraping plate. A working cavity is formed in the rear side of the base, a linkage mechanism is contained in the working cavity, a moving mechanism is arranged at the coupling position of the linkage mechanism and the scraper, and a driving mechanism is arranged at the driving end of the linkage mechanism. The microcapsule preparation device provided by the utility model has the advantages that ground raw materials can be uniformly spread, so that the filtering effect of the filter screen on the ground raw materials is ensured, the filtering speed is also improved, and the preparation quality and speed of soft capsules are further improved.

The utility model discloses a soft capsule drying device which relates to the technical field of medicine processing and comprises a first supporting frame, a drying cylinder used for bearing soft capsules and a heating assembly used for generating hot air flow, a first limiting sleeve is rotationally connected to the first supporting frame, an electric telescopic rod is arranged on one side of the first supporting frame, and a second limiting sleeve is arranged on the other side of the first supporting frame. The extending end of the electric telescopic rod is rotationally matched with a second limiting sleeve, the drying cylinder is coaxially and rotationally connected to the interiors of the first limiting sleeve and the second limiting sleeve, and the heating assembly is arranged on the side, away from the electric telescopic rod, of the first limiting sleeve in a matched mode and is rotationally matched with the drying cylinder; a barrel cover matched with one end of the drying barrel is arranged at the end, away from the first supporting frame, of the second limiting sleeve, a ventilation opening is formed in the barrel cover, and a driving assembly for driving the drying barrel to rotate is arranged on the second limiting sleeve. In the using process, each soft capsule is evenly heated, the situation that the soft capsules are clamped cannot occur, and using is more convenient.

1. The product name of the design product: bottle label (bilberry lutein beta-carotene soft capsule). 2. The use of the design product: label for the surface of the product packaging. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best indicates the design points: front view. 5. The design for which protection is sought includes color. 6. The design product is a flat product, omitting the left view, right view, top view, bottom view, and rear view, which is not commonly used.

This utility model discloses a capsule testing device, belonging to the technical field of capsule testing machines. Specifically, it relates to a multi-purpose, fully compatible capsule testing machine, comprising a feeding hopper, a rotary feeding device, two sets of testing stations, a conveying device, a synchronization device, a testing system, a rejecting system, a finished product collection device, and a control system. This utility model is compatible with the testing of three major types of materials: empty capsules, filled capsules, and soft capsules, and can accommodate the testing needs of different capsule models. It is easy to clean and maintain, and can operate stably and uniformly, improving the accuracy and stability of testing results. This project adopts machine vision inspection principles and high-speed image processing technology to perform fully automatic, blind-spot-free testing of capsule products. It quickly models and manages different product types, counts and statistically analyzes the test results, and automatically rejects defective products. It features fast testing speed, high testing accuracy, comprehensive technical service, strong upgrade capabilities, and simple and easy-to-use equipment.

1. The name of this design product: Packaging box (Double Whale Vitamin AD Soft Capsule Series). 2. Purpose of this design product: a packaging box for medicines and nutritional products. 3. The key design points of this design product are the combination of shape, pattern and color. 4. The picture or photo that best illustrates the key points of the design: Design 1 Stereoscopic Drawing 1. 5. The design for which protection is sought includes color. 6. Designate Design 1 as the base design.

The invention discloses a preparation method of omega-3 fatty acid ethyl ester 90 soft capsules, which comprises the following steps: 1) preparing raw materials and auxiliary materials: weighing gelatin, glycerol, purified water and omega-3 fatty acid ethyl ester 90 according to prescription dosage for later use; (2) preparing a glue solution, namely heating purified water to 80 DEG C, sequentially adding glycerol and gelatin for capsules, stirring until the gelatin for capsules is melted, carrying out vacuum stirring and degassing for more than 30 minutes, and standing and degassing for 30-60 minutes; 3) pelleting: adjusting the temperature of a capsule box, the temperature of a spraying body, the rotating speed of a main shaft and the refrigeration temperature of a roller, adjusting the thickness of a wet capsule skin, adding the omega-3 fatty acid ethyl ester 90 prepared in the step 1) into a hopper, and starting pelleting; and 4) drying: controlling the temperature of a drying chamber at 10-30 DEG C, controlling the humidity below 40%, and drying until the water content of the capsule skin is less than 13% to obtain the omega-3 fatty acid ethyl ester 90 soft capsule, the process is simple, and the prepared omega-3 fatty acid ethyl ester 90 soft capsule has good disintegration effect and stable performance.

The present disclosure relates to suspension-based pharmaceutical formulations for cold and flu medications, and more specifically to high-concentration suspension formulations and soft gel capsule dosage forms having reduced size, as well as methods of preparing the suspension formulations and soft gel capsules thereof.

1. Name of the product in this design: Packaging Box (Ethyl Eicosapentaenoic Acid Soft Capsules). 2. Intended use of this design: pharmaceutical packaging. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The application provides a preparation method of a soft capsule of Rana spinosa Mato Grosso oil red yeast powder, and belongs to the technical field of health food preparation. Specific weight parts of Rana spinosa freeze-dried powder 50 parts, red yeast powder 20-30 parts, Mato Grosso oil 100 parts and beta-cyclodextrin 10-20 parts are used as raw materials, the Rana spinosa freeze-dried powder is prepared through an optimized freeze-drying process, and the soft capsule is prepared after being mixed uniformly. The application realizes synergistic effect through scientific compounding of raw materials, can comprehensively regulate four indexes of blood lipids, and protects liver function at the same time. The beta-cyclodextrin embedding and soft capsule sealing double protection technology are adopted, so that the shelf life of the product is prolonged to 24 months. The prepared soft capsule has a remarkable effect of reducing blood lipids, is safe and has no side effects, is convenient to take, and is suitable for large-scale industrial production.

The utility model relates to the technical field of soft capsule equipment, and discloses a glue brush of a soft capsule machine, which solves the problems in the background technology, and comprises a glue brush roller, a brush sheet groove is arranged on the glue brush roller, a brush sheet is arranged in the brush sheet groove, a check ring for limiting the movement of the brush sheet is arranged on the glue brush roller, and preferably, the check ring is arranged on the glue brush roller. The number of the brush piece grooves can be flexibly set according to actual requirements so as to adapt to soft capsule production equipment of different scales or different types, the working efficiency is improved or the brushing effect is improved, preferably, each brush piece is of an independent detachable structure, each brush piece is independently installed in the groove in the glue brush roller, and the brush piece grooves can be flexibly arranged according to the actual requirements. The rubber brush roll has the advantages that if a certain brush piece is abraded or damaged, the brush piece can be conveniently detached and replaced, the whole rubber brush roll does not need to be replaced, the maintenance cost of equipment is reduced, and the high cost of overall replacement is avoided.

The invention provides a soft capsule helpful for improving the function of chloasma as well as a preparation method and application thereof, and relates to the technical field of health care products. The soft capsule comprises a mulberry leaf extract, a seville orange flower extract, a grape seed extract, an almond extract, donkey-hide gelatin powder, vitamin C and vitamin E. The soft capsule provided by the invention exerts the overall effect of improving chloasma through a multi-target synergistic mechanism from inside to outside: the mulberry leaf extract and the grape seed extract block melanogenesis from the source and resist ultraviolet damage by inhibiting tyrosinase activity and strongly resisting oxidation; the seville orange flower extract is used for soothing liver and regulating qi, and regulating internal pathogenesis; the almond extract and the donkey-hide gelatin powder have the effects of promoting blood circulation to remove blood stasis and nourishing yin and blood, improve microcirculation and nourish skin; vitamin C and vitamin E form an anti-oxidation cycle, so that melanin intermediates are directly reduced, and cell membranes are protected. All the raw materials supplement each other to jointly achieve the comprehensive effects of fading stains, brightening the skin color and improving the skin quality.

The present disclosure relates to compositions of microemulsion formulations for the delivery of lipophilic pharmacologically active agents or combinations of lipophilic pharmacologically active agents. The microemulsion formulations may be supplied as soft gel capsules for oral delivery or as solutions suitable for intravenous administration. The compositions find use in reducing inflammation and / or pain.

The utility model discloses an air pump feeding device of a soft capsule pelleting machine, which comprises an air pump, a sealing material box and a charging barrel, the output end of the air pump is communicated with the inside of the sealing material box through an air pipe, the sealing material box is communicated with the inside of the charging barrel through a conveying pipe, the conveying pipe is formed by connecting a vertical pipe and a horizontal pipe through a bent pipe, and the vertical pipe is connected with the horizontal pipe through a connecting pipe. The end, penetrating into the charging barrel, of the transverse pipe is connected with a spraying pipe, a T-shaped structure is formed between the spraying pipe and the transverse pipe, the spraying pipe is attached to the inner wall of the charging barrel, and the extension line where liquid spraying openings in the two ends of the spraying pipe are located is tangent to the inner wall of the charging barrel. Compared with manual feeding, a conveying pipeline formed by the air pump, the sealing material box and the conveying pipe is arranged, feeding is more convenient and labor-saving, meanwhile, the installation position of the spraying pipe in the material barrel is low, and the liquid spraying line of the spraying pipe is tangent along the inner wall of the material barrel, so that original material liquid in the material barrel is conveniently impacted and uniformly mixed during feeding, and the feeding efficiency is improved. And the feed liquid in the feed cylinder can be in a continuous motion state, so that the problem of layering of the feed liquid is reduced.

The application discloses a soft capsule pill press rubber forming and conveying system, which comprises a syringe and two sets of spreading boxes, rubber drum wheels and air coolers symmetrically arranged on the upper sides of the syringe, wherein flowing glue is coated on the rotating rubber drum wheel through the spreading box and forms the rubber extending to the syringe downward through the air cooler under the driving of the rubber drum wheel. The application improves and rearranges the spreading box, rubber drum wheel and air cooler in the old pill press, establishes a new rubber forming and conveying system, removes the multiple transmission felt wheels needed for the upward transmission of the rubber, makes the glue in the spreading box flow into the cooling channel of the air cooler from high to low, and forms the rubber directly entering the rotating die of the pressing die in the cooling channel, thereby reducing the use amount of paraffin oil.

The utility model discloses a soft capsule pill forming machine, and belongs to the technical field of capsule forming machines. A soft capsule pill forming machine comprises a rotationally-arranged rolling cage, a feeding port is formed in one end of the rolling cage, the rolling cage comprises a drying cage close to one end of the feeding port and a cooling cage far away from one end of the feeding port, a spiral channel is arranged between the drying cage and the cooling cage, a vortex tube is arranged below the drying cage, and the spiral channel is communicated with the spiral channel. A hot air outlet of the vortex tube faces the drying cage; the soft capsule pill drying device has the advantages that the heating mechanism is simple in structure, and dried soft capsule pills can be conveniently and rapidly cooled.

The utility model discloses a pill pressing machine for soft capsule production, and relates to the field of soft capsule production, in particular to a pill pressing machine for soft capsule production, which comprises two rotating molds mounted on a pill pressing machine main body, and the two rotating molds rotate relatively to press pills. A plurality of capsule pelleting grooves used for pelleting are formed in the outer side of the rotating mold, the sides, close to the interior of the rotating mold, of the middles of the capsule pelleting grooves are communicated with the interiors of the capsule pelleting grooves in a penetrating mode, and capsule blocking plates capable of pushing capsules to be discharged are movably installed at the communicating positions of the interiors of the rotating mold and the capsule pelleting grooves; according to the pill pressing machine for soft capsule production, pill pressing can be conducted through relative rotation of the rotating mold, then under driving of the rotating mold, a discharging pushing and guiding column can rotate, and under the relative action of a pushing and guiding roller, the discharging pushing and guiding column can gradually push a capsule material blocking plate.

The soft capsule pellet feeding mechanism comprises a flow dividing piece and a material dividing assembly, the flow dividing piece is provided with a closed material channel with two smooth ends, the upper end of the material channel is a feeding port, and the lower end of the material channel is a discharging port; the material distributing assembly comprises a material distributing wheel, the material distributing wheel rotates vertically, a material groove is formed in the circumferential side face of the material distributing wheel, the material distributing wheel partially enters the material channel, the width of the material distributing wheel is matched with the width of the material channel, and the circumferential side face of the material distributing wheel and the inner wall of the opposite flow distributing piece are arranged in a dynamic sealing mode. The material channel is divided into an upper section channel and a lower section channel by the material distributing wheel; the material trough upwards receives materials, the material distributing wheel rotates to enable the material trough to face downwards, the materials in the material trough enter the lower-section channel, and the materials in the upper-section channel are blocked by the material distributing wheel. The material storage amount in the material groove is the material amount of soft capsule filling, the material distributing wheel and the flow dividing piece are matched to enable the materials to enter the lower-section channel and be discharged from the discharging port in the lower end, and subpackaging and feeding of pellets are achieved.

The utility model discloses a soft capsule sorting device used in a conveying process, which comprises a mounting box, a screening mechanism, a conveying mechanism, a conveying mechanism, a sorting mechanism, a conveying mechanism, a sorting mechanism and a sorting mechanism, and the mounting box is internally provided with a partition plate; the screening mechanism is positioned between the outer walls of two sides of the partition plate and the inner walls of two sides of the mounting box; the vibration mechanism is located on the inner wall of the bottom of the mounting box and comprises a motor and two sliding blocks, an output shaft of the motor is fixedly connected with a rotating disc, a fixing block is arranged at the position, close to the edge, of the outer wall of one side of the rotating disc, and the outer wall of the fixing block is sleeved with a connecting rod; sliding grooves are formed in the middle of the partition plate and located on the inner walls of the two sides. The soft capsule sorting device used in the conveying process has the advantages that vibration caused by long-time manual pressing is avoided, the labor burden is relieved, automatic sorting is achieved, and the soft capsule sorting efficiency is improved.

The invention describes a method including the administration of a pharmaceutical composition. The administration includes dispensing a pharmaceutical filler composition comprising an active agent from a soft gel capsule into a patient's nasal cavity for nasal absorption or into the patient's oral cavity for pregastric absorption.

The invention relates to the field of fish oil capsule packaging equipment, in particular to fish oil soft capsule packaging equipment and a using method.The fish oil soft capsule packaging equipment comprises a base, a supporting seat is fixedly connected to the front side of the top of the base, a gear ring is rotationally connected to the axis position of the top of the supporting seat, and an adjusting box is fixedly connected to the top of the gear ring. The fish oil soft capsule packaging equipment is composed of an adjusting mechanism, a conveying detection mechanism and a transmission mechanism. Under the action of the adjusting mechanism, the fish oil capsules are driven by the adjusting box to rotate to the lower portion of the conveying detection mechanism to be detected, the qualified fish oil capsules cannot deform when making contact with the detection plate, at the moment, the detection plate overturns upwards to switch the state of the L-shaped main guide column, and the L-shaped main guide column cannot make contact with the main adjusting plate; and when the qualified fish oil capsules rotate to the positions of the packaging bottles along with the adjusting box, the L-shaped auxiliary guide columns and the auxiliary adjusting plates are matched to slide, so that the qualified fish oil capsules fall into the packaging bottles from the positions of the corresponding discharging holes.