329 results about "Soft gel capsule" patented technology

The present invention discloses automated soft capsule production equipment and a speed regulation method, relating to the field of food and pharmaceutical equipment manufacturing, and is designed to achieve automated soft capsule production. The automated soft capsule production equipment includes an electronic control system, a liquid infusion system, a gelatin strip conveyor system, and a soft capsule pressing and molding system. The electronic control system is connected to the liquid infusion system, the gelatin strip conveyor system, and the soft capsule pressing and molding system, respectively. The gelatin strip conveyor system includes a thickness sensor for measuring the thickness of the conveyed gelatin strip and transmitting a measurement signal to the electronic control system. The gelatin strip conveyor system also includes an angle sensor assembly for measuring the tightness of the conveyed gelatin strip and transmitting a measurement signal to the electronic control system. The electronic control system receives and processes the measurement signal and transmits a control signal to a motor in the gelatin strip conveyor system to adjust the thickness or tightness of the gelatin strip. The liquid infusion system automatically closes and opens the infusion switch via the electronic control system, and the soft capsule pressing and molding system automatically controls the mold compression or release via the electronic control system.

The invention discloses a coenzyme Q10 soft capsule appearance defect detection method based on image recognition, relates to the technical field of capsule detection, and solves the problem that the reliability and pertinence of a detection result are insufficient due to the fact that different types of defects such as size deviation and breakage wrinkles cannot be effectively recognized. According to the method, the standard image and the to-be-analyzed image set are determined from a large number of images, and then the image with the most significant difference between the to-be-analyzed features and the focus is selected for ellipse perimeter comparison; according to the mode, the analysis range can be efficiently narrowed, the area where wrinkles, damage or abnormal sizes possibly exist can be accurately positioned, and the pertinence and efficiency of defect analysis are improved.

The invention discloses a soft capsule dissolution detection device with a self-cleaning function, the detection device comprises a tank body, an outer frame, an evaluation mechanism, a stirring mechanism, a cleaning mechanism, an aeration mechanism and a detection mechanism, the evaluation mechanism comprises an upper sample frame, the stirring mechanism comprises a lock pin disc, a first side frame and a layering mechanism, and the upper sample frame is fixedly connected with the lock pin disc; the layering mechanism is connected with the detection mechanism through a pipeline, the tank body is provided with an upper edge and aeration holes, the cleaning mechanism comprises an outer concave ring and a third motor, the outer frame is fixedly connected with the tank body, the aeration mechanism and the detection mechanism, the aeration holes are fixedly connected with the aeration mechanism, the first side frame and the third motor are fixedly connected with the upper edge, and the outer concave ring is rotationally connected with the upper edge; the invention relates to the technical field of capsule detection devices, samples of different prescriptions and processes can be distinguished and evaluated, the capsule content precipitation condition fits the reality through the simulated stomach bag wriggling effect, and rapid self-cleaning can be achieved.

The invention discloses an automatic mold alignment device and method for a rolling model type soft capsule pelleting machine and the soft capsule pelleting machine, relates to the field of manufacturing of food and medicine equipment, and aims to realize automation of a soft capsule production link. According to the automatic mold alignment scheme of the rolling model soft capsule pelleting machine based on sensor detection, the sensor is used for detecting and recognizing the zero position phase difference of the two mold rollers, the position information is transmitted to the control system, and the control system automatically adjusts the relative positions of the two mold rollers, so that the automatic alignment of the two mold rollers is achieved. Therefore, the purpose of automatic alignment of the mold is achieved. According to the invention, the defects of the traditional manual alignment technology are overcome, and the quality and efficiency of soft capsule production are improved. Various sensor scheme selections are provided, including the laser displacement sensor, the contact type displacement sensor and the industrial camera, the appropriate scheme can be selected according to the actual demand, and remarkable economic benefits and social benefits are achieved.

The invention discloses a calcium liposome for promoting bone health as well as a preparation method and application thereof. The calcium liposome is prepared from the following components in parts by weight: 3 to 7 parts of phospholipid composition, 0.1 to 0.35 part of phytosterol, 1 to 5 parts of insoluble calcium, 1 to 7.5 parts of protein and 0.1 to 1 part of modifier, wherein the phospholipid composition consists of egg yolk lecithin, phosphatidylinositol and distearoyl phosphatidylcholine, and the mass ratio of the egg yolk lecithin to the phosphatidylinositol to the distearoyl phosphatidylcholine is (8-12): (7-11): ( The specific phospholipid composition obtained through screening is combined with phytosterol to serve as a membrane material to wrap a compound of insoluble calcium and protein, so that the dispersity and the stability of the prepared calcium liposome are obviously improved, when the calcium liposome is applied to preparation of calcium soft capsules, the oil leakage phenomenon is obviously reduced, meanwhile, the absorption of an organism to calcium is also enhanced, and the bioavailability of the calcium soft capsules is improved. Particularly, the bone mineral density and the bone calcium content of an organism are obviously increased, healthy development of bones is promoted, and the difficulty and the pain point of insoluble calcium applied to the fields of functional foods, health care products, biological medicines and the like are effectively solved.

The invention relates to the technical field of computer vision, in particular to a method for quickly identifying apparent defects of fish oil soft capsules. The method comprises the following steps: acquiring a reference region in a fish oil soft capsule image to be identified; obtaining a seed point in the reference area and a corresponding growth threshold value, carrying out area growth, and obtaining all foreign matter reference points in the reference area; acquiring an overlapping coefficient of a non-foreign matter reference point in the reference area, acquiring a new seed point and a corresponding new growth threshold when the overlapping coefficient of the non-foreign matter reference point is greater than a preset overlapping coefficient threshold, performing area growth, and acquiring a new foreign matter reference point; all the foreign matter reference points and the new foreign matter reference points in the reference area form a foreign matter area of the reference area, the foreign matter area of the area where each capsule is located in the gray level image is obtained, and defect recognition is conducted on the fish oil soft capsule image. According to the invention, the complete foreign matter area can be rapidly obtained, and the apparent defect identification of the fish oil soft capsule is more accurate.

The utility model discloses a soft capsule drying device which relates to the technical field of medicine processing and comprises a first supporting frame, a drying cylinder used for bearing soft capsules and a heating assembly used for generating hot air flow, a first limiting sleeve is rotationally connected to the first supporting frame, an electric telescopic rod is arranged on one side of the first supporting frame, and a second limiting sleeve is arranged on the other side of the first supporting frame. The extending end of the electric telescopic rod is rotationally matched with a second limiting sleeve, the drying cylinder is coaxially and rotationally connected to the interiors of the first limiting sleeve and the second limiting sleeve, and the heating assembly is arranged on the side, away from the electric telescopic rod, of the first limiting sleeve in a matched mode and is rotationally matched with the drying cylinder; a barrel cover matched with one end of the drying barrel is arranged at the end, away from the first supporting frame, of the second limiting sleeve, a ventilation opening is formed in the barrel cover, and a driving assembly for driving the drying barrel to rotate is arranged on the second limiting sleeve. In the using process, each soft capsule is evenly heated, the situation that the soft capsules are clamped cannot occur, and using is more convenient.

1. The product name of the design product: bottle label (bilberry lutein beta-carotene soft capsule). 2. The use of the design product: label for the surface of the product packaging. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best indicates the design points: front view. 5. The design for which protection is sought includes color. 6. The design product is a flat product, omitting the left view, right view, top view, bottom view, and rear view, which is not commonly used.

This utility model discloses a capsule testing device, belonging to the technical field of capsule testing machines. Specifically, it relates to a multi-purpose, fully compatible capsule testing machine, comprising a feeding hopper, a rotary feeding device, two sets of testing stations, a conveying device, a synchronization device, a testing system, a rejecting system, a finished product collection device, and a control system. This utility model is compatible with the testing of three major types of materials: empty capsules, filled capsules, and soft capsules, and can accommodate the testing needs of different capsule models. It is easy to clean and maintain, and can operate stably and uniformly, improving the accuracy and stability of testing results. This project adopts machine vision inspection principles and high-speed image processing technology to perform fully automatic, blind-spot-free testing of capsule products. It quickly models and manages different product types, counts and statistically analyzes the test results, and automatically rejects defective products. It features fast testing speed, high testing accuracy, comprehensive technical service, strong upgrade capabilities, and simple and easy-to-use equipment.

1. The name of this design product: Packaging box (Double Whale Vitamin AD Soft Capsule Series). 2. Purpose of this design product: a packaging box for medicines and nutritional products. 3. The key design points of this design product are the combination of shape, pattern and color. 4. The picture or photo that best illustrates the key points of the design: Design 1 Stereoscopic Drawing 1. 5. The design for which protection is sought includes color. 6. Designate Design 1 as the base design.

The invention discloses a preparation method of omega-3 fatty acid ethyl ester 90 soft capsules, which comprises the following steps: 1) preparing raw materials and auxiliary materials: weighing gelatin, glycerol, purified water and omega-3 fatty acid ethyl ester 90 according to prescription dosage for later use; (2) preparing a glue solution, namely heating purified water to 80 DEG C, sequentially adding glycerol and gelatin for capsules, stirring until the gelatin for capsules is melted, carrying out vacuum stirring and degassing for more than 30 minutes, and standing and degassing for 30-60 minutes; 3) pelleting: adjusting the temperature of a capsule box, the temperature of a spraying body, the rotating speed of a main shaft and the refrigeration temperature of a roller, adjusting the thickness of a wet capsule skin, adding the omega-3 fatty acid ethyl ester 90 prepared in the step 1) into a hopper, and starting pelleting; and 4) drying: controlling the temperature of a drying chamber at 10-30 DEG C, controlling the humidity below 40%, and drying until the water content of the capsule skin is less than 13% to obtain the omega-3 fatty acid ethyl ester 90 soft capsule, the process is simple, and the prepared omega-3 fatty acid ethyl ester 90 soft capsule has good disintegration effect and stable performance.

The present disclosure relates to suspension-based pharmaceutical formulations for cold and flu medications, and more specifically to high-concentration suspension formulations and soft gel capsule dosage forms having reduced size, as well as methods of preparing the suspension formulations and soft gel capsules thereof.

1. Name of the product in this design: Packaging Box (Ethyl Eicosapentaenoic Acid Soft Capsules). 2. Intended use of this design: pharmaceutical packaging. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The application provides a preparation method of a soft capsule of Rana spinosa Mato Grosso oil red yeast powder, and belongs to the technical field of health food preparation. Specific weight parts of Rana spinosa freeze-dried powder 50 parts, red yeast powder 20-30 parts, Mato Grosso oil 100 parts and beta-cyclodextrin 10-20 parts are used as raw materials, the Rana spinosa freeze-dried powder is prepared through an optimized freeze-drying process, and the soft capsule is prepared after being mixed uniformly. The application realizes synergistic effect through scientific compounding of raw materials, can comprehensively regulate four indexes of blood lipids, and protects liver function at the same time. The beta-cyclodextrin embedding and soft capsule sealing double protection technology are adopted, so that the shelf life of the product is prolonged to 24 months. The prepared soft capsule has a remarkable effect of reducing blood lipids, is safe and has no side effects, is convenient to take, and is suitable for large-scale industrial production.

The utility model relates to the technical field of soft capsule equipment, and discloses a glue brush of a soft capsule machine, which solves the problems in the background technology, and comprises a glue brush roller, a brush sheet groove is arranged on the glue brush roller, a brush sheet is arranged in the brush sheet groove, a check ring for limiting the movement of the brush sheet is arranged on the glue brush roller, and preferably, the check ring is arranged on the glue brush roller. The number of the brush piece grooves can be flexibly set according to actual requirements so as to adapt to soft capsule production equipment of different scales or different types, the working efficiency is improved or the brushing effect is improved, preferably, each brush piece is of an independent detachable structure, each brush piece is independently installed in the groove in the glue brush roller, and the brush piece grooves can be flexibly arranged according to the actual requirements. The rubber brush roll has the advantages that if a certain brush piece is abraded or damaged, the brush piece can be conveniently detached and replaced, the whole rubber brush roll does not need to be replaced, the maintenance cost of equipment is reduced, and the high cost of overall replacement is avoided.

The invention provides a soft capsule helpful for improving the function of chloasma as well as a preparation method and application thereof, and relates to the technical field of health care products. The soft capsule comprises a mulberry leaf extract, a seville orange flower extract, a grape seed extract, an almond extract, donkey-hide gelatin powder, vitamin C and vitamin E. The soft capsule provided by the invention exerts the overall effect of improving chloasma through a multi-target synergistic mechanism from inside to outside: the mulberry leaf extract and the grape seed extract block melanogenesis from the source and resist ultraviolet damage by inhibiting tyrosinase activity and strongly resisting oxidation; the seville orange flower extract is used for soothing liver and regulating qi, and regulating internal pathogenesis; the almond extract and the donkey-hide gelatin powder have the effects of promoting blood circulation to remove blood stasis and nourishing yin and blood, improve microcirculation and nourish skin; vitamin C and vitamin E form an anti-oxidation cycle, so that melanin intermediates are directly reduced, and cell membranes are protected. All the raw materials supplement each other to jointly achieve the comprehensive effects of fading stains, brightening the skin color and improving the skin quality.

The present disclosure relates to compositions of microemulsion formulations for the delivery of lipophilic pharmacologically active agents or combinations of lipophilic pharmacologically active agents. The microemulsion formulations may be supplied as soft gel capsules for oral delivery or as solutions suitable for intravenous administration. The compositions find use in reducing inflammation and / or pain.

The application discloses a soft capsule pill press rubber forming and conveying system, which comprises a syringe and two sets of spreading boxes, rubber drum wheels and air coolers symmetrically arranged on the upper sides of the syringe, wherein flowing glue is coated on the rotating rubber drum wheel through the spreading box and forms the rubber extending to the syringe downward through the air cooler under the driving of the rubber drum wheel. The application improves and rearranges the spreading box, rubber drum wheel and air cooler in the old pill press, establishes a new rubber forming and conveying system, removes the multiple transmission felt wheels needed for the upward transmission of the rubber, makes the glue in the spreading box flow into the cooling channel of the air cooler from high to low, and forms the rubber directly entering the rotating die of the pressing die in the cooling channel, thereby reducing the use amount of paraffin oil.

The utility model discloses a soft capsule pill forming machine, and belongs to the technical field of capsule forming machines. A soft capsule pill forming machine comprises a rotationally-arranged rolling cage, a feeding port is formed in one end of the rolling cage, the rolling cage comprises a drying cage close to one end of the feeding port and a cooling cage far away from one end of the feeding port, a spiral channel is arranged between the drying cage and the cooling cage, a vortex tube is arranged below the drying cage, and the spiral channel is communicated with the spiral channel. A hot air outlet of the vortex tube faces the drying cage; the soft capsule pill drying device has the advantages that the heating mechanism is simple in structure, and dried soft capsule pills can be conveniently and rapidly cooled.

The utility model discloses a pill pressing machine for soft capsule production, and relates to the field of soft capsule production, in particular to a pill pressing machine for soft capsule production, which comprises two rotating molds mounted on a pill pressing machine main body, and the two rotating molds rotate relatively to press pills. A plurality of capsule pelleting grooves used for pelleting are formed in the outer side of the rotating mold, the sides, close to the interior of the rotating mold, of the middles of the capsule pelleting grooves are communicated with the interiors of the capsule pelleting grooves in a penetrating mode, and capsule blocking plates capable of pushing capsules to be discharged are movably installed at the communicating positions of the interiors of the rotating mold and the capsule pelleting grooves; according to the pill pressing machine for soft capsule production, pill pressing can be conducted through relative rotation of the rotating mold, then under driving of the rotating mold, a discharging pushing and guiding column can rotate, and under the relative action of a pushing and guiding roller, the discharging pushing and guiding column can gradually push a capsule material blocking plate.

The soft capsule pellet feeding mechanism comprises a flow dividing piece and a material dividing assembly, the flow dividing piece is provided with a closed material channel with two smooth ends, the upper end of the material channel is a feeding port, and the lower end of the material channel is a discharging port; the material distributing assembly comprises a material distributing wheel, the material distributing wheel rotates vertically, a material groove is formed in the circumferential side face of the material distributing wheel, the material distributing wheel partially enters the material channel, the width of the material distributing wheel is matched with the width of the material channel, and the circumferential side face of the material distributing wheel and the inner wall of the opposite flow distributing piece are arranged in a dynamic sealing mode. The material channel is divided into an upper section channel and a lower section channel by the material distributing wheel; the material trough upwards receives materials, the material distributing wheel rotates to enable the material trough to face downwards, the materials in the material trough enter the lower-section channel, and the materials in the upper-section channel are blocked by the material distributing wheel. The material storage amount in the material groove is the material amount of soft capsule filling, the material distributing wheel and the flow dividing piece are matched to enable the materials to enter the lower-section channel and be discharged from the discharging port in the lower end, and subpackaging and feeding of pellets are achieved.

The invention describes a method including the administration of a pharmaceutical composition. The administration includes dispensing a pharmaceutical filler composition comprising an active agent from a soft gel capsule into a patient's nasal cavity for nasal absorption or into the patient's oral cavity for pregastric absorption.

The utility model discloses soft capsule production equipment capable of reducing energy consumption, and relates to the technical field of soft capsule production, the soft capsule production equipment comprises a glue melting tank and a bottom frame, the top surface of the glue melting tank is fixedly provided with a mounting frame, the bottom surface of the mounting frame is fixedly provided with a round rod, the outer wall of the round rod is provided with a rotatable rotating block, and the bottom surface of the rotating block is fixedly provided with a rotating shaft. The bottom end of the rotating block is fixedly connected with a scraping plate; according to the device disclosed by the utility model, the fixed gear is fixedly arranged, the two transmission gears are meshed with the fixed gear, and the scraping plate is finally attached to the inner wall of the glue melting tank, so that the rotating rod can simultaneously revolve and rotate on the inner wall of the glue melting tank in the use process of the device, the mixing speed is increased, and the energy consumption is reduced; the scraping plate connected to the bottom of the rotating block can clean the inner wall of the glue melting tank in the rotating process of the rotating block, glue blocks are prevented from being attached to the inner wall of the glue melting tank, meanwhile, only one motor is needed to drive all assemblies in the process, and resource consumption is reduced.

This invention discloses a compound soft capsule based on camellia oil and its preparation method, belonging to the field of health food processing technology. Using camellia oil as the core carrier, this invention combines extracts of honeysuckle, green tea, and licorice root, using beeswax as a specific suspending agent, without adding any wetting agents. By optimizing the entire process parameters from ultrasonic extraction of traditional Chinese medicine, content preparation, sol-gel, pelleting, shaping, washing, drying, and packaging, a compound soft capsule with high stability, good flowability, and clear anti-inflammatory effects is prepared. This invention solves the technical problems of easy oxidation and deterioration of camellia oil, insufficient deep processing in the camellia oil industry, and low economic added value. The resulting soft capsules can effectively inhibit pro-inflammatory factors such as TNF-α, IL-2, and IFN-γ, increase the level of the anti-inflammatory factor IL-10, and have a significant protective effect against lipopolysaccharide-induced acute kidney injury. The process of this invention is controllable and suitable for industrial production, which can significantly extend the camellia oil industry chain and enhance the competitiveness of the local woody oilseed industry.

The invention relates to the technical field of medicine storage, and discloses an AI-based coenzyme Q10 soft capsule dynamic storage environment control system, which comprises a data acquisition module used for acquiring temperature data, humidity data, illumination intensity data and medicine state data; the data preprocessing module is used for cleaning the collected data, removing abnormal values and noise data, and performing normalization processing to obtain preprocessed data; the model prediction module is used for inputting the preprocessed data into an LSTM (Long Short Term Memory) model, predicting the change trend of environmental parameters in a future time window, simulating a degradation path of the activity of the coenzyme Q10 and outputting a prediction result; the environment regulation and control module is used for generating a control strategy according to the prediction result and realizing dynamic adjustment of environment parameters through an execution mechanism; according to the invention, the dynamic and accurate regulation and control of the storage environment are realized, the manual intervention is reduced, the labor cost is reduced, and the overall efficiency of storage management is improved.

The invention discloses a self-sterilizing packaging device for soft capsule production, relates to the technical field of soft capsule packaging devices, and comprises a cleaning mechanism arranged on a No. 1 fixed plate, the cleaning mechanism comprising a No. 1 connecting plate fixedly connected to the No. 1 fixed plate, circular plates equidistantly arranged and rotatably arranged on the No. 1 connecting plate, and a No. 1 pulley fixedly arranged on each of the circular plates. The invention provides a cleaning mechanism, and a cleaning roller is used to transport the soft capsules that have been granulated in a limiting path while rotating, so that the soft capsule surface is wiped by the soft cleaning fabric on the cleaning roller, so as to wipe off the oil stains on each soft capsule, and wipe off the surface of the soft capsule partially stained with liquid leaked from the damaged soft capsule, so as to prevent the quality of the soft capsule from being affected by the liquid leaked from the damaged soft capsule, ensure the quality of the soft capsule when it is bottled, and avoid being affected by the liquid leaked from the damaged soft capsule.

The utility model discloses a batching device for soft capsule production, which belongs to the technical field of soft capsule production and processing and comprises a batching device, an air pump is mounted at the top end of a tank cover, the top end of an air pipe is mounted at the air outlet end of the air pump, a pipe groove is formed in the middle end of a side pipe in a penetrating manner, and a rubber ring is mounted on the outer side of the bottom end of an insertion pipe. A rubber ring is plugged into a pipe groove, an insertion pipe and the rubber ring are inserted into the pipe groove, a material receiving tank is moved into an open groove, the loaded raw materials are poured into the insertion pipe, an air extracting pump and a motor start to operate, air is blown to the raw materials in a feeding pipe opening through a bent pipe, the insertion pipe and the pipe groove, and the raw materials are also scattered by rotating a slope rod; the raw materials are mixed from the beginning of feeding, the time for stirring the raw materials is shortened, after mixing is completed, the air cylinder shrinks, one end of the semicircular block moves up and down, the moving semicircular block vibrates, and falling of the mixed materials is facilitated.

The invention relates to a coenzyme Q10 soft capsule and a preparation method thereof, and belongs to the technical field of health care products. The problems that an existing product wall material is insufficient in compactness and poor in stability, and contents are prone to seeping out are solved. The soft capsule is composed of a content and a wall material according to a specific mass ratio, the content contains coenzyme Q10, soybean oil, vitamin E and phospholipid, and the wall material contains gelatin, glycerin, an aloe-tremella mixed extract and purified water. The aloe-tremella mixed extract is prepared through pretreatment of fresh aloe, preparation of tremella powder, construction of a mixed system, ultrasonic extraction and post-treatment, natural active mucopolysaccharide and tremella polysaccharide contained in the aloe-tremella mixed extract can be synergistically crosslinked, and the aloe-tremella mixed extract, gelatin and glycerin jointly construct a compact wall material structure. The preparation method is simple in process, easy in parameter control and free of special equipment, the product can improve illumination and oxidation stability and reduce the content exudation rate, physicochemical properties and use safety are both considered, and the preparation method is suitable for industrial production.

The utility model belongs to the technical field of soft capsule production, and particularly relates to a soft capsule sealing performance testing device which comprises an airtight box body and a sealing top cover detachably installed at the top end of the airtight box body, and further comprises an electromagnetic valve, a pressure sensor and a pressure sensor, a first flange mouthpiece is fixed on the sealing top cover, and the electromagnetic valve is fixed on the first flange mouthpiece; a second flange mouthpiece is fixed on the sealing top cover, and the pressure gauge is fixed on the second flange mouthpiece; the third flange connecting nozzle is fixed on the sealing top cover; according to the utility model, the airtight box body is in the vacuum state and is used for testing the sealing performance of the soft capsule, the reading of the pressure gauge can accurately reflect the sealing performance of the soft capsule, the observation is convenient, the problem of misjudgment is avoided, and the testing efficiency and precision are improved.