The invention discloses an all-fiber-texture large-size one-piece flange fan main shaft forging method which comprises the following steps of material selection, heating, primary firing forging, secondary firing forging, heat treatment after forging, rough turning, ultrasonic flaw detection, hardening and tempering, semifinishing, lossless flaw detection, body sampling, mechanical property testing and stable heat treatment. Compared with the conventional twice-forging and welded flange main shaft production method, the all-fiber-texture large-size one-piece flange fan main shaft forging method has the advantages that the welding working procedures are reduced, the time is saved, the raw material consumption is reduced, and the production cost is lowered; a forged flange main shaft is of an all-fiber-texture structure, so that the natural defects that the welded flange is low in balance property and easy to deform and the root is easy to break are totally overcome; a requirement of a large-size fan on the main shaft design is met.