The application discloses a long-acting
hydrogen-releasing
microsphere in the
stomach and use of the
microsphere as a
drug in treatment of
gastritis, and belongs to the field of pharmaceutical preparations and
hydrogen treatment. The composition provided by the application is composed of a
hydrogen production micro-particle as a core and a sustained-
release agent composed of hydroxypropyl
methyl cellulose and
ethyl cellulose. By selecting specific components and processes, the
microsphere has good floatability and long-acting hydrogen-releasing capacity. The microsphere can float in the gastric juice environment and gradually release hydrogen, so that the sustained anti-oxidation and anti-inflammatory effects are realized, and the microsphere is suitable for treatment of gastric
inflammation.