The invention provides a flushing 
system (1) configured to flush the 
pericardial cavity (PC) of a patient, wherein the 
system comprises: an infusion liquid outlet (4) to connect a first tube(20) having an infusion liquid lumen to guide a flow of infusion liquid from the 
system to the 
pericardial cavity, and an 
effusion liquid inlet (6) to connect to a second tube (21) having an 
effusion liquid lumen to guide the 
effusion liquid flow from the 
pericardial cavity to the system, a flow 
rate control system to control the flow rate of the infusion liquid flow at the infusion liquid outlet (4) on the basis of 
multiple sensor signals, wherein the flow 
rate control system comprises: a 
control unit (5) to provide a 
control signal on the basis of the sensor signals, and a pump device (3) to pump infusion liquid to the infusion liquid outlet (4) at an infusion liquid flow rate, wherein the infusion liquid flow rate is adjustable by the 
control signal of the 
control unit (5) and wherein the sensor signals registered by the 
control unit (5) comprise: an infusion liquid 
signal representative for the infusion liquid flow to the pericardial cavity, an effusion liquid 
signal representative for the effusion liquid flow rate from the pericardial cavity, a 
blood volume signal generated by a 
hematocrit sensor (12) representative for a 
blood loss flow rate in the effusion liquid from the pericardial cavity, and a 
pressure control signal representative for the pressure in the pericardial cavity generated by a 
pressure sensor positioned inside or in connection with the first tube (20), the second tube (21) or the pericardial cavity. The invention also provides a method of monitoring the 
blood loss volume or flow rate from the 
pericardium based on 
multiple sensor signals as well as, a method of treatment of postoperative cardiac patients in order to reduce the risk of cardiac 
tamponade, reduce post-operative 
blood loss and reduce the accumulation of blood and clots in the pericardial cavity, wherein the pericardial cavity of the patient is flushed with a flushing system according to the invention.