64 results about "Nitric oxide gas" patented technology

The utility model relates to a purification device for nitric oxide gas. The purification device comprises an extraction tower, a desorption tower, an alkaline washing tower, a condenser, an ethanol absorption tower and an adsorption tower which are communicated in sequence, a feed port of the extraction tower is communicated with a crude product gas source pipeline, a discharge port of the extraction tower is communicated with a feed port pipeline of the desorption tower, a discharge port of the desorption tower is communicated with a feed port pipeline of the alkaline washing tower, a discharge port of the alkaline washing tower is communicated with a feed port pipeline of the condenser, and a discharge port of the condenser is communicated with a feed port pipeline of the ethanol absorption tower. A discharge port of the ethanol absorption tower is communicated with a feed port of the adsorption tower through a pipeline, and a discharge port of the adsorption tower is communicated with a product collection bottle through a pipeline. Through the extraction tower, the desorption tower, the alkaline washing tower, the condenser, the ethanol absorption tower and the adsorption tower which are arranged in sequence, the device can efficiently purify nitric oxide gas, and each treatment unit can remove specific impurities, so that the finally obtained nitric oxide gas is ensured to have high purity.

The application discloses a light-controlled nitric oxide releasing hollow single-atom nanoscale enzyme, a preparation method and application, and belongs to the technical field of biomedical materials. In the application, spherical silica nanoparticles are used as a template, and a structure of copper ion-polydopamine coated silica nanoparticles is formed on the surface of the silica nanoparticles through self-polymerization of dopamine and chelation of copper ions, and the spherical structure is maintained with the support of the silica nanoparticles. The copper ion-polydopamine coated silica nanoparticles are pyrolyzed to obtain a copper-based single-atom nanoscale enzyme with a carbon skeleton, and a hollow spherical single-atom nanoscale enzyme is obtained after etching. Nitric oxide donor molecules are loaded into the hollow of the hollow spherical single-atom nanoscale enzyme to obtain the light-controlled nitric oxide releasing hollow single-atom nanoscale enzyme. The application can realize the synergistic treatment effect of photothermal therapy, nitric oxide gas therapy and biological catalytic therapy, is used for efficiently removing bacteria and biofilms at an infected wound site, and effectively promotes the healing of the bacteria-infected wound.

The invention, which relates to the technical field of automobile manifold processing, discloses an automobile manifold airtightness detection device comprising a detection bench provided with a positioning module used for positioning an automobile manifold. The automobile manifold comprises a main air pipe, and the main air pipe communicates with a plurality of branch air pipes. A blocking module and a first gas transmission module are arranged on the detection table, the blocking module is used for blocking the orifice of the branch gas pipe, and the first gas transmission module is used for inputting nitric oxide gas into the main gas pipe; wherein a sealing box is further arranged on the detection table, an opening is formed in the direction, facing the detection table, of the sealing box, a lifting module is arranged on the detection table, and the lifting module is used for driving the sealing box to ascend and descend; according to the detection method, the leakage point can be positioned, and in the detection process, detection liquid cannot be attached to the automobile manifold, so that subsequent cleaning and drying treatment is not needed, the detection precision and efficiency are effectively improved, and batch production of the automobile manifold is facilitated.

The invention relates to a gas supply method and device based on nitric oxide controllable pulse ionization generation and a nitric oxide therapeutic apparatus, and the method comprises the steps: carrying out the feature extraction of different dimensions of a to-be-ionized gas, and obtaining the basic features of an ionization environment and the component features of an ionization medium; generating a pulse ionization control sequence according to the basic characteristics of the ionization environment, the component characteristics of the ionization medium and the historical pulse ionization control sequence sample; the pulse ionization control sequence is sent to the ionization generation device to execute pulse ionization operation, a nitric oxide gas product is generated, and gas supply operation is executed according to the generated nitric oxide gas product; monitoring a real-time ionization process state of the pulse ionization operation, and generating a real-time ionization process state set according to an ionization discharge intensity characteristic, a medium temperature distribution characteristic and a gas generation rate characteristic in the real-time ionization process state; and performing matching analysis on the real-time ionization process state set and historical real-time ionization process state characteristics to generate a new pulse ionization control sequence.

The present application relates to the technical field of gas sensitive material synthesis, in particular to a preparation of a hemin nanosphere-graphene composite material and its application in detecting nitric oxide gas, and provides a preparation method of the hemin nanosphere-graphene composite material, wherein the hemin is first treated at high temperature in a ketone solvent, and then the hemin nanosphere is obtained after purification and drying; and the hemin nanosphere and graphene oxide are subjected to alcohol thermal reaction to obtain the hemin nanosphere-graphene composite material. The hemin nanosphere-graphene composite material is prepared into a gas sensitive electrode and applied to the detection of nitric oxide gas, and the electrode has good effects, can work at room temperature, and has the characteristics of strong selectivity, high sensitivity, low power consumption, high stability and fast recovery.

After trench etching but before formation of a gate insulating film, a 15-minute to 60-minute heat treatment under a mixed gas atmosphere containing nitric oxide gas and nitrogen gas at a temperature from 1200 degrees C. to 1350 degrees C. and a 30-minute to 75-minute heat treatment under a nitrogen gas atmosphere held at the temperature of the 15-minute to 60-minute heat treatment are successively performed, oxidizing etching damage of inner walls of trenches. The total treatment time of the heat treatments includes a total time of at least 90 minutes when the temperature is a predetermined maximum temperature. The oxide layer of the trench inner walls is removed, exposing a clean face. Emission intensity of band edge emission for SiC obtained by CL analysis of surface areas of the inner walls of the trenches is at least equal to the emission intensity of the band edge emission for SiC obtained by the CL analysis of a surface free of dry etching.

The utility model discloses a reaction device for normal-pressure leaching of nitric acid, which is characterized in that in the reaction process, nitric oxide in a reaction kettle enters an absorption tower through a nitric oxide exhaust outlet, a first pipeline and a nitric oxide gas inlet, and an oxygen supply device supplies oxygen to the absorption tower; an absorption liquid circulating pump I conveys an absorbent in the absorption tower circulating device to an absorbent circulating inlet I and enters the absorption tower, the absorbent absorbs nitric oxide gas to form nitric acid, nitric oxide released in the process reacts with oxygen to generate nitrogen dioxide, and the nitrogen dioxide reacts with the absorbent to generate nitric acid; according to the device, nitrogen oxide gas generated in the reaction process can be absorbed, the obtained absorption acid (nitric acid) can be cyclically applied to the leaching reaction, and tail gas can be discharged after reaching the standard. And the method is environment-friendly.

The utility model relates to the technical field of dilute nitric acid production, in particular to a dilute platinum nitrate net precious metal recovery device which comprises a baffle, a guide cover fixedly connected to the interior of the baffle, an exhaust pipe fixedly connected to the center of the guide cover, a communicating pipe communicated with one side of the exhaust pipe, and a plurality of bending parts installed on the outer side of the communicating pipe. The other ends of the bent parts are fixedly connected with transverse parts, and the other ends of the transverse parts are arranged in a sealed mode. Laminated filtering materials are wound on the outer sides of the bent part and the transverse part; when the gas filter is used, mixed gas such as nitric oxide gas needing to be filtered enters the shell through the gas inlet connector and is filtered through the filtering material, metal particles are attached to the surface of the filtering material, and the gas enters the shell through the through holes in the surfaces of the transverse part and the bent part and is exhausted through the exhaust pipe. When the dilute nitric acid device is shut down and the platinum net is replaced, the new filter element is synchronously replaced, precious metal particles in the old filter element are recycled, and precious metal lost from the platinum net of the oxidizing furnace is continuously recycled in the dilute nitric acid production process.

The invention relates to a preparation method and application of nitric oxide gas release hydrogel for chronic wound repair of diabetes mellitus, and belongs to the technical field of biomedical materials. According to the invention, hyaluronic acid is modified by tris (hydroxymethyl) aminomethane with mechanical properties and structural stability, so that the stability of the hydrogel is improved, and the problem that traditional hydrogel is fragile and easy to collapse is solved; the epsilon-polylysine is introduced, so that the hydrogel has a sterilization effect, and infectious bacteria at chronic wounds can be efficiently sterilized; nitric oxide donor small molecules are introduced into hydrogel, and on-demand release in a pathological environment is realized by combining a high active oxygen response mechanism; through dynamic inclusion of the hollow meso-porous silicon-selenium hybrid nanostructure and cyclodextrin, the drug loading efficiency and release stability of the nanoparticles are further improved, and the nanoparticles are endowed with good responsiveness, controllability and synergistic function. The prepared nitric oxide gas release hydrogel can significantly accelerate healing of chronic wound surfaces of diabetes, the preparation process is mild, simple and convenient, and large-scale production is easy.

The present invention relates to a liquid nitric oxide releasing solution (NORS) comprised of at least one nitric oxide releasing compound and at least one acidifying agent, wherein the NORS provides an extended release of a therapeutically effective amount of nitric oxide gas (gNO). The present invention also relates to a liquid NORS comprised of at least one nitrite compound having a concentration of no greater than about 0.5% w / v and at least one acidifying agent, wherein the NORS releases a therapeutically effective amount of gNO. The present invention also relates to a method for the treatment of a wound in a human, the method comprising administering to the human a liquid NORS comprised of at least one nitric oxide releasing compound and at least one acidifying agent, wherein the NORS provides an extended release of a therapeutically effective amount of gNO. The present invention also relates to a method for the treatment, prevention, or reduction of incidence of a disease or disorder in a human in need thereof, the method comprising administering to the human a liquid NORS comprised of at least one nitrite compound at a concentration of no greater than about 0.5% w / v and at least one acidifying agent, wherein the NORS releases a therapeutically effective amount of gNO.

The present application relates to a kind of purification method of nitric oxide gas, comprising the following steps: crude nitric oxide gas is imported into extraction column, and the extraction phase obtained after extraction is imported into resolution column for temperature resolution;Nitric oxide gas resolved is imported into ethanol absorption tower after alkali washing tower and condenser;Again imported into the adsorption tower filled with 13X molecular sieve;After adsorption, the gas is collected into product collection bottle, and the purity of more than 99.99% nitric oxide product is obtained.The present application uses ferrous sulfate solution as extractant, extracts refined nitric oxide, realizes the efficient extraction of nitric oxide by the coordination reaction of ferrous ion and nitric oxide in the purification process, then uses ethanol as absorbent, utilizes the significant difference in solubility of nitric oxide and nitrous oxide in ethanol, can selectively absorb the nitrous oxide impurity difficult to remove, finally uses 13X molecular sieve to further remove nitrous oxide, which is beneficial to reduce disproportionation reaction and improve product purity.

The invention provides a heat pipe enhanced heat exchange reducing absorption tower for nitric acid preparation, which comprises a tower body and a heat pipe exchanger, nitric oxide gas enters from the tower bottom, absorption liquid enters from the tower top, and the nitric oxide gas and the absorption liquid contact and react in the tower body to generate nitric acid, and is characterized in that the tower body is divided into a plurality of sections from top to bottom, the diameters of the sections are different, and the diameters of the sections are different in the direction from top to bottom; the diameter of the tower body is gradually increased; a plurality of heat pipe heat exchangers are arranged, an inclined angle is formed between the heat pipe heat exchangers and the tower body, an evaporation section of each heat pipe is arranged in the tower body, and a condensation end of each heat pipe extends out of the tower body. The design of the reducing absorption tower is matched with the concentration of nitrogen oxide, so that the absorption efficiency can be remarkably improved.

The invention discloses traditional Chinese medicine polysaccharide composite hydrogel as well as a preparation method and application thereof. The traditional Chinese medicine polysaccharide composite hydrogel is formed by a traditional Chinese medicine polysaccharide loaded photothermal agent and a nitric oxide donor, wherein the traditional Chinese medicine polysaccharide is selected from one or more of scutellaria baicalensis polysaccharide, astragalus polysaccharide, rhizoma bletillae polysaccharide, honeysuckle polysaccharide, wild chrysanthemum flower polysaccharide and pinellia ternate polysaccharide; the mass ratio of the photo-thermal agent to the traditional Chinese medicine polysaccharide is 1: (8-15); the mass ratio of the nitric oxide donor to the traditional Chinese medicine polysaccharide is 1: (8-15). The traditional Chinese medicine polysaccharide composite hydrogel can be used for treating MRSA infected wounds and has the effect of cooperating with traditional Chinese medicine polysaccharide, photo-thermal treatment and nitric oxide gas treatment.

The application discloses a method for generating nitric oxide gas, and belongs to the field of gas preparation and medical treatment, and is characterized in that the method for generating nitric oxide gas is to mix liquid medicament with solid medicament, to make the liquid medicament and the solid medicament react chemically, so as to generate nitric oxide gas with a certain concentration, the effective component of the solid medicament is nitrosyl iron sulfate, and the liquid medicament is one or a mixture of several kinds of alkali solution or slurry and salt solution or slurry. The application further discloses a corresponding device for generating nitric oxide gas.

Systems and methods are provided for generating a nitric oxide (NO) gas. A plasma generating device is configured to produce a plasma to ionize a flow of a reactant gas into a product gas that comprises NO, NO2, oxygen, and nitrogen gases. A controller is configured to regulate an amount of NO in the product gas using parameters as input to the controller. A gas separation device comprising a housing including product gas inlets and sweep fluid inlets to receive a flow of the product gas and a flow of the sweep fluid such that the flows of product gas and sweep fluid are opposed flows. A membrane is positioned inside the housing and permits flow of a subset of gases of the product gas therethrough so the product gas exiting the housing includes NO.

A method for removing sulfur oxides and nitrogen oxides from air flow belongs to the technical field of air pollution control, and is characterized in that treated air flow is introduced into a desulfurization reactor, a nitric acid solution absorbent is introduced into the reactor, sulfur dioxide in the air flow and nitric acid in the absorbent are subjected to an oxidation-reduction reaction, and the sulfur oxides and the nitrogen oxides are removed. Nitric oxide gas generated in the reaction process of the sulfur dioxide and nitric acid is guided into a denitration reactor along with the gas flow, meanwhile, ferric chloride absorbent slurry is guided into the denitration reactor, and the nitric oxide gas in the gas flow and ferric chloride are subjected to a chemical reaction to be absorbed; nitric oxide gas released by regeneration of the saturated absorbent after absorption is oxidized, nitric acid is recycled as a desulfurization absorbent for recycling, and ferric salt absorbent slurry is recycled after regeneration.

The utility model discloses a nitric oxide gas metal ion sampling device. The nitric oxide gas metal ion sampling device comprises a gas inlet pipeline, a buffer bottle, a primary absorption bottle, a secondary absorption bottle, a tail gas absorption bottle and a tail gas adsorption assembly which are arranged in sequence, a flow controller is arranged on the gas inlet pipeline and connected with a gas inlet of the buffer bottle, a gas outlet of the buffer bottle is connected with a gas inlet of the first-stage absorption bottle, a gas outlet of the first-stage absorption bottle is connected with a gas inlet of the second-stage absorption bottle through a first pipeline, and a gas outlet of the second-stage absorption bottle is connected with a gas inlet of the tail gas absorption bottle through a pipeline; a gas outlet of the tail gas absorption bottle is connected with the tail gas adsorption assembly. The nitric oxide gas metal ion separation device has the beneficial effects that the separation of nitric oxide gas metal ions is realized, and the whole device is simple, simple and convenient to operate, safe and reliable, and cannot cause pollution to air and harm to sampling personnel.

The application discloses a purification method for high-purity nitric oxide gas production, which comprises the following steps: adding sulfuric acid drops into a sodium nitrite solution to generate a nitric oxide crude product, removing nitrogen dioxide and carbon dioxide by alkali washing, removing water by pre-cooling, removing nitrogen by deep cooling, and finally obtaining high-purity nitric oxide gas. The residual concentration of nitrous oxide in the purified nitric oxide gas can be reduced to below 3 ppm, and the purity of the nitric oxide reaches above 99.99%. The method can efficiently remove the nitrous oxide impurities, has the advantages of high product yield and simple operation, and has a wide practical application prospect.

The invention provides a gas sampling system and a medical gas transmission system, and relates to the field of sampling monitoring equipment. The gas sampling system comprises a sampling pipe, one end of the sampling pipe is communicated with an inspiration branch of a mechanical ventilation loop, the other end of the sampling pipe is communicated with a gas detection system, and nitric oxide gas is injected into the inspiration branch; the sampling pipe is used for leading gas containing nitric oxide in the gas suction branch to the gas detection system; at least one part of the sampling pipe is a water vapor permeable section, and the pipe wall of the water vapor permeable section is made of a water vapor permeable material; water content is reduced after gas passes through the sampling pipe. The gas sampling system provided by the invention solves the technical problems of inconvenience in use caused by frequent water pouring of a water collection cup or infection risk caused by bacterium breeding caused by long-time water collection of a large-capacity appliance in the prior art.

A method for generating nitric oxide gas for generating a constant concentration of nitric oxide gas and an apparatus for use in the method for generating nitric oxide gas are provided. The method for generating nitric oxide gas involves mixing a liquid drug with a solid drug and generating nitric oxide gas through a chemical reaction. The active ingredient of the solid drug is ferric nitrosodilator (Fe(NO) X Cl3,x≦3) or a hydrate thereof. The active ingredient of the liquid medicament is a carbonate salt of an alkali metal, an alkaline earth metal, or a transition metal, or a corresponding acid salt, base salt, or complex salt, or a mixture of the above compounds.

The invention discloses a self-driven nano antibacterial material as well as a preparation method and application thereof, and belongs to the technical field of biomedical antibacterial materials. The preparation method comprises the following steps: firstly preparing mesoporous silica nanoparticles loaded with calcium peroxide, then adsorbing polyacrylic acid, precipitating on the nanoparticles by utilizing island-shaped nucleation and seed polymerization processes of a PDA layer, generating anisotropic coverage of the PDA layer on the nanoparticles by seed polymerization of dopamine, and preparing Janus structure nanoparticles by controlling polymerization time. Then L-arginine is further grafted on the polydopamine to obtain a self-driven nano-antibacterial material, and the self-driven nano-antibacterial material is mixed with sterile PBS to prepare paste for root canal disinfection. The paste generates an asymmetrically distributed photothermal effect and nitric oxide gas under the excitation of 808nm near-infrared light, and the formed dual-fuel pushes a nano motor to go deep into narrow intertubule traffic and dentin tubules, so that the targeting and penetrating capabilities on a biological membrane are improved, and an excellent sterilizing effect is achieved.

The present invention relates to the technical field of single-atom metal catalysts, and particularly to a method for electrochemically reducing nitric oxide to hydroxylamine based on a single-atom iron catalyst. First, the single-atom metal catalyst and Nafion are dissolved in isopropanol to obtain a mixed solution, and then the mixed solution is drop-coated onto carbon paper and post-treated to obtain a working electrode; then a flow-through electrolytic cell is used to construct a two-compartment three-electrode reaction system; finally, nitric oxide is introduced, and an overpotential is applied to the working electrode to carry out an electrochemical reaction to obtain hydroxylamine. The present invention uses a single-atom iron catalyst to electrochemically reduce toxic and harmful nitric oxide gas into hydroxylamine with high added value, and has high activity and high yield; moreover, the electrochemical reaction carried out by the present invention is carried out at normal temperature and pressure, and no harmful by-products are generated.

Provided are methods for delivering NO to patients, systems for delivering NO to patients, devices for generation and storage of NO, and methods for generating NO. Described are systems providing single-step and dual-step dilution of high concentration NO for delivery to a patient without generating toxic levels of NO2. Also described are NO storage cartridges for use in the systems.

The invention discloses a production process and device for preparing liquid nitrogen tetroxide by recycling nitric oxide. Nitrogen oxides in the tail gas are respectively absorbed by water and alkali liquor to prepare a nitric acid solution and a sodium nitrate-nitrous acid solution; a dilute nitric acid solution and a sodium nitrate and nitrite solution are respectively stored and then mixed to enter a nitric oxide generation tower for reaction to generate nitric oxide gas and a sodium nitrate aqueous solution. The nitric oxide gas is lightly oxidized by using oxygen in the nitric oxide generation tower, then enters the oxidation absorption tower and is heavily oxidized by using concentrated nitric acid, so that the nitric oxide gas is completely converted into nitrogen dioxide gas, and the concentrated nitric acid is used for absorption at the upper section of the oxidation absorption tower to form fuming nitric acid. Fuming nitric acid is heated by steam, and liquid nitrogen tetroxide is produced after condensation. The non-condensable gas contains a small amount of nitrogen oxides, and then passes through a denitration device. By adopting the device and the process, the nitrogen oxide in the recovered waste gas can be effectively ensured to be prepared into liquid nitrogen tetroxide, and the content of the nitrogen oxide in the waste gas outlet is reduced.

The invention discloses a nitrosohemoglobin-loaded membrane fusion bionic nano-carrier as well as a preparation method and application of the nitrosohemoglobin-loaded membrane fusion bionic nano-carrier. According to the membrane fusion bionic nano-carrier, a membrane shell is formed by hybridizing and fusing synthetic phospholipid and a platelet membrane, an aqueous solution of nitrosohemoglobin is encapsulated in the membrane shell, and the nitrosohemoglobin is prepared by carrying out deoxidation treatment on hemoglobin and then reacting the treated hemoglobin with nitric oxide molecules; the membrane fusion bionic nano-carrier has good biocompatibility and natural targeting property, and can quickly and efficiently target the focus of cardiovascular and cerebrovascular diseases, and the delivered nitrosohemoglobin not only retains the biological activity of vasodilation and the like of nitric oxide gas molecules, but also has paramagnetism, can effectively enhance the magnetic resonance development effect, and can be used for preparing a biological medicine for treating cardiovascular and cerebrovascular diseases. And a new tool can be provided for effective delivery of nitric oxide molecules in ischemic cardiovascular and cerebrovascular disease lesions and magnetic resonance imaging diagnosis as a carrier.

The invention relates to the technical field of nitric acid production devices, and discloses a nitric acid production high-pressure reaction cooling device suitable for a high-temperature environment, the nitric acid production high-pressure reaction cooling device comprises a reaction tank, a cooling water tank is placed on the left side of the reaction tank, and a nitrogen dioxide high-pressure tank is placed on the right side of the reaction tank; a nitric oxide gas inlet pipe is communicated between the reaction tank and the nitrogen dioxide high-pressure tank, the top end of the reaction tank is rotatably connected with a water supply pipe, the bottom end of the nitrogen dioxide high-pressure tank is communicated with a nitrogen dioxide gas outlet pipe, and the inner wall of the reaction tank is rotatably connected with a first water cooling pipe. According to the device, a servo motor drives a water supply pipe to rotate to drive spraying nozzles on a spraying support to rotate, the contact reaction range of spraying water mist and nitrogen dioxide gas is widened, and the nitrogen dioxide gas is diffused from the periphery of the outer wall of a flow dividing pipe through a waterproof ball at the top end of the flow dividing pipe; the nitrogen dioxide gas and water mist formed by spraying can be fully contacted and reacted, so that the conversion rate of nitric acid can be improved.

The present invention relates to a liquid nitric oxide releasing solution (NORS) comprised of at least one nitric oxide releasing compound and at least one acidifying agent, wherein the NORS provides an extended release of a therapeutically effective amount of nitric oxide gas (gNO). The present invention also relates to a liquid NORS comprised of at least one nitrite compound having a concentration of no greater than about 0.5% w / v and at least one acidifying agent, wherein the NORS releases a therapeutically effective amount of gNO. The present invention also relates to a method for the treatment of a wound in a human, the method comprising administering to the human a liquid NORS comprised of at least one nitric oxide releasing compound and at least one acidifying agent, wherein the NORS provides an extended release of a therapeutically effective amount of gNO. The present invention also relates to a method for the treatment, prevention, or reduction of incidence of a disease or disorder in a human in need thereof, the method comprising administering to the human a liquid NORS comprised of at least one nitrite compound at a concentration of no greater than about 0.5% w / v and at least one acidifying agent, wherein the NORS releases a therapeutically effective amount of gNO.

This invention relates to a method for preparing a nitric oxide absorbent for flue gas from a coal-fired power plant and its application, comprising the following steps: preparing tridentate aldehyde through a multi-step organic synthesis reaction; preparing triangular prism cage-like molecules; preparing a nitric oxide absorbent stock solution; and formulating the nitric oxide absorbent. The beneficial effects of this invention are: employing the principle of physical adsorption, the triangular prism cage-like compound captures NO through physical adsorption, and through desorption, high-purity nitric oxide gas can be obtained and reused for NO molecule absorption. This method is safer than traditional chemical methods, effectively avoiding the environmental hazards caused by ammonia escape and the impact of byproducts such as ammonium bisulfate on the normal operation of the unit, and also features high recycling rate and long service life.