31results about How to "Reduce vascular resistance" patented technology

Systems, methods and devices are provided for the targeted treatment of a variety of medical conditions by directly neuromodulating a target anatomy associated with the condition while minimizing or excluding undesired neuromodulation of other anatomies. Typically, the target anatomy includes one or more dorsal root ganglia, dorsal roots, dorsal root entry zones, or portions thereof. Such target stimulation areas are utilized due in part to their effect on the sympathetic nervous system.

The present invention relates to compositions and methods for treatment of blood and blood products using gaseous nitric oxide. The treatment involves the contacting blood or a blood product with gaseous nitric oxide.

The present invention provides methods of using electromagnetic radiation in the visible portion of the spectrum to modulate mitochondrial function in the treatment of various conditions, including Alzheimer's disease, other dementias, hypoxia and diabetic peripheral neuropathy, and sensory disorders of the extremities.

The present invention provides methods of using electromagnetic radiation in the visible portion of the spectrum to modulate mitochondrial function in the treatment of various conditions, including Alzheimer's disease, other demential, hypoxia and diabetic peripheral neuropathy, and sensory disorders of the extremities.

This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity. In some cases, a polypeptide provided herein can have natriuretic activities without inducing excessive hypotension. This document also provides methods and materials for inducing natriuretic activities within a mammal.

The invention discloses a plaster for treating pains in neck, shoulder, waist and legs. The plaster is made by mainly using Caulis Sinomenii, Aconitum kusnezoffii, Radix Aconiti, Boswellia carteri, myrrh, Viciaamoena Fisch, centipede, Ligusticum wallichii, Common Threewingnut Root, rhizoma corydalis, dahurian angelica root, ramulus mori, Semen Brassicae, scorpio, pawpaw, Zoacys Dhumnades, Radix Clematidis, dragon's blood, Mythic Fungus, Salvia miltiorrhiza, Rhizoma Cibotii, Panax Notoginseng, Incised Notopterygium, Radix Angelicae Pubescentis, medicine called Lingxian Divaricate Saposhnikovia Root, Radix Stephaniae Tetrandrae, Gentiana macrophylla, Rhizoma Drynariae, unprepared Polygonum multiflorum Thunb, tortoise shell, Nux Vomica, stir-baked squama manitis, lumbricus, rhizoma corydalis, borneol, Manchurian wildginger, Herbal Ephedrae, Cortex Acanthopanacis, safflower, camphor and rosin. The plaster is a special medicine for treating rheumatoid arthritis, traumatic injury, pains in neck, shoulder, waist and legs, and hyperosteogeny patients, is a traditional black plaster dosage form prepared with Chinese herbal medicines as raw materials, is a traditional Chinese medicinal plaster dosage form with definite therapeutic effects, and cures more than 100000 patients through the combination of traditional Chinese medicinal channel and collateral theory and local infected position application treatment.

This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity. In some cases, a polypeptide provided herein can have natriuretic activities without inducing excessive hypotension. This document also provides methods and materials for inducing natriuretic activities within a mammal.

The present invention provides compounds that possess inhibitory activity against PDE-3 and L-type calcium channels. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating cardiovascular disease, stroke, epilepsy, ophthalmic disorder or migraine.

2-Substituted-5′-O-(1-boranotriphosphate)adenosine derivatives having at position 2 a radical R1 selected from the group consisting of H; halogen; O-hydrocarbyl; S-hydrocarbyl; NR3R4; and hydrocarbyl optionally substituted by halogen, CN, SCN, NO2, OR3, SR3 or NR3R4; wherein R3 and R4 are each independently H or hydrocarbyl or R3 and R4 together with the nitrogen atom to which they are attached form a saturated or unsaturated heterocyclic ring optionally containing 1-2 further heteroatoms selected from oxygen, nitrogen and sulfur, and pharmaceutically acceptable salts or diastereoisomers thereof or a mixture of diastereoisomers, are useful for treatment of type 2 diabetes.

The invention discloses a method for preparing an enzyme from kudzuvine roots and mulberry fruits. The method comprises the following steps that the kuzuvine roots and the mulberry fruits are smashed by a pulping machine and mixed to be uniform; a mixture is poured into a fermentation container, a precooled disodium hydrogen phosphate-citric acid buffer solution is added, a complex enzyme and ferrous carbonate are added, and enzymatic low-temperature extraction is conducted; filtrate is extracted to prepare first-time fermentation liquor, the first-time fermentation liquor is inoculated with lactobacillus plantarum to prepare second-time fermentation liquor, and the second-time fermentation liquor is subjected to solid-liquid separation to obtain the enzyme. According to the method, through enzymatic low-temperature extraction, the nutritional ingredients in the kudzuvine roots and the mulberry fruits can be fully extracted, the product effect and edible safety are greatly improved, the technology is simple, and the prepared enzyme fully retains the effective ingredients of the kudzuvine roots and leaves and the mulberry fruits, is stable in quality, has multiple effects of reducing blood vessel resistance, improving cardio-cerebral blood circulation, reducing the myocardial oxygen consumption and the like and can achieve the nutrition and health care effects.

The present invention provides methods of using electromagnetic radiation in the visible portion of the spectrum to modulate mitochondrial function in the treatment of various conditions, including Alzheimer's disease, other dementias, hypoxia and diabetic peripheral neuropathy, and sensory disorders of the extremities.

The invention belongs to the technical field of foods and discloses a coffee carnitine fruit juice beverage and a preparation method thereof. The coffee carnitine fruit juice beverage is prepared from the following substances in parts by weight: 100 to 130 parts of water, 10 to 15 parts of coconut jelly, 1 to 1.5 parts of jelly powder, 5 to 7 parts of erythritol, 5 to 6 parts of maltitol, 1 to 2 parts of coffee powder, 0.5 to 1 part of resistant dextrin, 0.2 to 1 part of radix puerariae powder, 0.1 to 0.3 part of L-carnitine, 0.1 to 0.2 part of fructooligosaccharide, 0.02 to 0.05 part of acesulfame, 0.01 to 0.03 part of sucralose, 0.02 to 0.03 part of aspartame, 1 to 3 parts of concentrated pear juice, 0.1 to 0.3 part of citric acid and 0.1 to 0.3 part of coffee essence. The product disclosed by the invention has a pure coffee flavor; people can have a satiety feeling after drinking the beverage so that the effect of low-calorie meal replacement is realized.

The invention provides a collagen hard candy and a preparation method thereof, the collagen hard candy is prepared by 75-85kg of sugar, 20-30kg of maltodextrin, 8-10kg of water, 15-20kg of Chinese herbal medicine extract product and 10-25kg of collagen powder. By adding fish scale collagen and Chinese herbal medicine extract product being used as food and drug, the nutrition value of candy is increased, preparation method is simple, industrialization is easy, and the collagen hard candy provides the basis for exploitation and application of fish scale collagen.

The invention provides a gingko fluid which comprises gingko leaf extract and water. The technical key point of the gingko fluid is that: the weight ratio of the gingko leaf extract to water is 1 to 3000-15000; the gingko leaf extract is gingko flavone and terpene lactones. No additional element exists in the gingko fluid of the invention, thereby completely exerting the efficacies of the gingko flavone and terpene lactones; the long-term drinking of the gingko fluid can increase the blood flow volume, reduce the vascular resistance, improve the function of cerebrovascular circulation, protect the brain cells from damages caused by cerebral ischemia, dilate coronary artery, prevent stenocardia and miocardial infarction, restrain the collection of blood platelets, prevent thrombus from formation, eliminate harmful oxidative free radical, improve immunity, has a function of cancer prevention and anti-aging, and also can dissolve cholesterin, dilate micrangium, improve microcirculation, has an obvious efficacy in maintaining the normal state of the haem and cholesterin in the artery and peripheral vessel, can prevent brain dysfunction and is beneficial to the recovery from arteriosclerosis, hypertension, hyperlipemia, coronary artery disease, stenocardia and other diseases.

The invention discloses a traditional Chinese medicine composition with cardiovascular and cerebrovascular protective effects. Specifically, it is composed of the following raw materials: kudzu root, cassia seed, bamboo leaf flavone, tangerine peel and green tea. It is also disclosed that the traditional Chinese medicine composition of the present invention has the preparation forms of teabag, powder, oral liquid, tablet, powder and capsule. And the use of the traditional Chinese medicine compound of the present invention in the preparation of medicines or health products for treating and / or preventing cardiovascular disease, cerebrovascular disease, hypertension, diabetes, hyperlipidemia, obesity, and immunocompromised diseases or diseases.

The invention discloses a compound combination with taohongsiwu decoction used as a source, and relates to the field of medicines. The compound combination with the taohongsiwu decoction used as the source is prepared by mixing quercetin (0.1-10 mg), kaempferol (0.1-10 mg), luteolin (0.1-5 mg), myricetin (0.1-10 mg), beta-sitosterol (0.1-10 mg) and baicalein (0.1-10 mg). Through systematic experiments, the therapeutic effects are proven.

The invention discloses an alkaline extract for antibiosis and antiphlogosis, and a preparation method thereof. The alkaline extract for antibiosis and antiphlogosis comprises, by weight, 80-100 parts of a 20-30% alkaloidi sophorae tannate medicine, 10-15 parts of stachydrine and 10-15 parts of berberine. The preparation method comprises the following steps: extraction of the alkaloidi sophorae tannate medicine, extraction of the stachydrine, extraction of the berberine, and preparation of the target alkaline extract. The alkaline extract for antibiosis and antiphlogosis has the advantages of wide application range, multiple effective components, and realization of function complementation and promotion of the effective components, and the preparation method has the advantages of high extraction efficiency, high purity of the obtained product, and easiness in realization.

The invention relates to a formula of traditional Chinese medicine, especially a foot flooding medicament for treating hyperosteogeny. The formula is used in treatment of hyperosteogeny, especially cervical vertebra hyperosteogeny, with the functions of increasing cerebrovascular flow, reducing blood vessel resistance, improving brain blood supply, improving microcirculation, expanding blood vessel and fine artery, reducing blood viscosity, preventing plug and removing plug; it also can improve the functional obstacle caused by ischaemia.

The invention relates to a heart-nourishing tea infusion, which belongs to the field of nutritious foods, has a good effect and becomes effective fast. The heart-nourishing tea infusion is prepared from ginseng leaves, safflower, radix puerariae, phospholipids of egg yolk, black tea and the like. The heart-nourishing tea infusion has the functions of supporting body resistance, reinforcing qi, nourishing blood, promoting blood circulation to remove blood stasis, nourishing the heart and unblocking veins and has the advantages of good effect and fast effectiveness.

The present invention provides methods of using electromagnetic radiation in the visible portion of the spectrum to modulate mitochondrial function in the treatment of various conditions, including Alzheimer's disease, other demential, hypoxia and diabetic peripheral neuropathy, and sensory disorders of the extremities.

The invention discloses a traditional Chinese medicine composition for treating fracture and rheumatic bone diseases and a method for preparing the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises rhizoma et radix notopterygii, radix angelicae pubescentis, fructus chaenomelis, radix achyranthis bidentatae, radix et rhizoma rhei, radix aconiti kusnezoffii, radix aconiti brachypodi, codonacanthus pauciflorus, radix angelicae sinensis, herba pteridis multifidae, ox bones, fructus citri sarcodactylis, radix paeoniae alba, radix angelicae dahuricae, dried scolopendra, herba speranskiae tuberculatae, folium artemisiae argyi and plant oil. Components in the traditional Chinese medicine composition include, by weight, 9-15 parts of rhizoma et radix notopterygii, 5-10 parts of radix angelicae pubescentis and 7-12 parts of fructus chaenomelis. The traditional Chinese medicine composition and the method have the advantages that effective componentsof medicines can be quickly permeated through foci, the blood circulation of lesion parts can be improved, vascular resistance can be lowered, activity of necks, shoulders, waists and knee joints canbe quickly recovered, effects of activating blood circulation to dissipate stasis, dredging main and collateral channels, inducing resuscitation, chilling bones, dispelling wind, eliminating dampness,activating the blood circulation, eliminating toxicants, promoting reunion of fractured bones, promoting the blood circulation and stopping pain can be realized by the traditional Chinese medicine composition prepared by the aid of the method, diversified diseases such as the fracture, traumatic injury, rheumatic bone pain and arthralgia can be internally and externally treated by the traditionalChinese medicine composition, and obvious curative effects can be realized by the traditional Chinese medicine composition; the traditional Chinese medicine composition is free of optional side effect or skin irritation, and relapse can be prevented after the diseases are treated by the traditional Chinese medicine composition.

The invention discloses a method for preparing an enzyme from kudzuvine roots and mulberry fruits. The method comprises the following steps that the kuzuvine roots and the mulberry fruits are smashed by a pulping machine and mixed to be uniform; a mixture is poured into a fermentation container, a precooled disodium hydrogen phosphate-citric acid buffer solution is added, a complex enzyme and ferrous carbonate are added, and enzymatic low-temperature extraction is conducted; filtrate is extracted to prepare first-time fermentation liquor, the first-time fermentation liquor is inoculated with lactobacillus plantarum to prepare second-time fermentation liquor, and the second-time fermentation liquor is subjected to solid-liquid separation to obtain the enzyme. According to the method, through enzymatic low-temperature extraction, the nutritional ingredients in the kudzuvine roots and the mulberry fruits can be fully extracted, the product effect and edible safety are greatly improved, the technology is simple, and the prepared enzyme fully retains the effective ingredients of the kudzuvine roots and leaves and the mulberry fruits, is stable in quality, has multiple effects of reducing blood vessel resistance, improving cardio-cerebral blood circulation, reducing the myocardial oxygen consumption and the like and can achieve the nutrition and health care effects.

The invention provides a preparation method of powder for dredging channels and collaterals, and relates to the technical field of health care. According to a 'natural food material' key technology, the powder is prepared from the following raw materials in parts by weight: 45 parts of ginkgo leaves, 45 parts of salviae miltiorrhizae, 45 parts of peach kernels, 45 parts of earthworms, 45 parts ofendothelium corneum gigeriae galli, 45 parts of pine needles, 45 parts of pine barks, 45 parts of loofah, 45 parts of panax notoginseng, 10 parts of rhizoma atractylodis macrocephalae, 10 parts of American ginseng, 10 parts of saffron crocus, 15 parts of yams, 10 parts of radix pueraiae, 10 parts of carrots, 10 parts of radix angelicae and 10 parts of apples; the preparation method comprises the following steps: after the raw materials are washed and dried, grinding the raw materials into 80-100-mesh powder; and packaging the10 parts by weight of the powder in each bag, so as to obtain a finished product of powder for dredging the channels and collaterals. A using method of the powder for dredging the channels and collaterals comprises the following steps: 10 g of the finished product of the powder is administered after being dissolved with warm water after a meal three times every day. The powder is used for health care. Natural food materials are taken as the raw materials, and the method is simple and easy, so that the powder is suitable for different kinds of people, is stable and reliable in effect and is beneficial for promotion due to low cost.

The invention provides a collagen hard candy and a preparation method thereof, the collagen hard candy is prepared by 75-85kg of sugar, 20-30kg of maltodextrin, 8-10kg of water, 15-20kg of Chinese herbal medicine extract product and 10-25kg of collagen powder. By adding fish scale collagen and Chinese herbal medicine extract product being used as food and drug, the nutrition value of candy is increased, preparation method is simple, industrialization is easy, and the collagen hard candy provides the basis for exploitation and application of fish scale collagen.

The invention relates to externally applied traditional Chinese medicine ointment for treating cervical-shoulder syndromes and a preparation method. The ointment is prepared from 15-20 parts of croton crassifolius, 2-3 parts of radix panacis quinquefolii, 2-3 parts of cornu cervi pantotrichum, 3-5 parts of eretmochelys imbricata, 10-20 parts of rubi fructus, 6-9 parts of flos carthami, 10-15 parts of licorice, 15-20 parts of semen brassicae, 6-9 parts of unprocessed radix aconite, 12-17 parts of twoflower micromeria, 10-20 of rhizoma atractylodis macrocephalae, 10-20 parts of bulbus allii macrostemonis, 12-17 parts of fructus cnidii, 2-3 parts of scorpions, 6-9 parts of realgar, 10-30 parts of semen momordicae and 10-30 parts of semen ricini. The ointment is proper and rigorous in formula compatibility, the preparation method is unique, and the ointment can rapidly cure hyperosteogeny and has effects of taking effect quickly and being short treatment course, high in cure rate and low in cost. The ointment also has a unique treatment effect on rheumatism, rheumatoid arthritis, low back and leg pain, shoulder periarthritis, limb numbness, sciatica, hyperosteogeny, lumbar disc herniation, cervical spondylosis, ankylosing spondylitis, breast hyperplasia, various pain persistent ailments, fracture sequelae and femoral head necrosis.

The invention discloses a black plaster for treating hyperplasia of mammary glands and a preparation method thereof, indicating hyperplasia of mammary glands, lobular hyperplasia of breast, breast mass, breast distension, pain, etc, it is prepared from the following raw materials and oleum sesami, Huang Dan decoct into ointment, the main raw materials are composed of the following parts by weight:10 to 15 part of angelica, 6 to 15 part of red peony root, 6 to 15 part of chuanxiong rhizome, 6 to 15 part of turmeric root, 10-15 part of fried rhizoma corydalis, 10 to 30 part of salvia miltiorrhiza, 6 to 10 part of safflower, 3 to 10 part of trogopterorum, 6 to 10 part of fritillary bulb, 10 to 30 part of prunella vulgaris, 6-15 part of rhizoma cyperi, 6-15 parts of radix bupleuri, 10-15 partof radix Linderae, 9-15 parts of pericarpium Citri Reticulatae viride, 6-15 parts of fructus Aurantii, 6-15 parts of pericarpium Trichosanthis, 10-30 part of oyster, 6-10 parts of carapax Trionycis preparata, 3-10 parts of semen Sinapis Albae, 6-10 parts of semen Vaccariae, 6-10 parts of flos Rosae Rosae, 3-10 parts of Olibanum, 3-10 parts of Myrrha, 6-10 parts of Bombyx Batryticatus and 1-3 parts of Scolopendra.

The invention relates to a Chinese medicinal preparation, in particular to heard-brain benefiting dropping pills for treating cardiovascular and cerebrovascular diseases and a method for preparing the same. The invention aims to solve the problem of treating cardiovascular and cerebrovascular diseases by natural plant medicaments. The dropping pill is characterized by consisting of the following raw material medicaments in part by weight: 13 to 17 parts of astragalus, 5 to 7 parts of sanchi, 8 to 10 parts of safflower, 8 to 10 parts of cape jasmine fruit and 1 to 5 parts of borneol. In the heard-brain benefiting dropping pills of the invention, the water soluble polyethylene glycol solid dispersion technique is used to disperse effective components of the medicaments on water soluble carriers in a molecular, colloidal, amorphous or ultrathin state, so that the degree of dispersion of the medicaments is improved, the medicament granularity is reduced, and the specific surface area is increased; because the carriers are water soluble, the dissolvability of the medicaments is improved, the dissolution rate is increased, the biological utilization rate is improved, the clinical curing effect is improved, and the aim of quick response is achieved; and thus, the heard-brain benefiting dropping pills are suitable to be used for treating cardiovascular and cerebrovascular diseases.

The invention provides a medicament for treating stroke disease. The medicament is prepared from the following raw materials in parts by weight: 200 to 260 parts of raw radix astragali seu hedysari, 120 to 160 parts of radix notoginseng, 80 to 100 parts of radix paeoniae rubra, 30 to 50 parts of mulberry twig, 50 to 75 parts of rhizoma chuanxiong, 40 to 60 parts of safflower flower, 30 to 60 partsof rhizoma acori graminei, 25 to 45 parts of caulis bambusae in taeniam, 20 to 45 parts of Chinese angelica root tail, 15 to 25 parts of sappan wood, 25 to 50 parts of leech, 30 to 50 parts of fructus viticis, 20 to 60 parts of cactus fruit, 15 to 35 parts of rhubarb stir-fried with wine, 5 to 15 parts of fructus physalis peruvianae, 40 to 55 parts of gadfly, 5 to 15 parts of radix stephaniae tetrandrae, 10 to 25 parts of peach kernel, 25 to 35 parts of earthworm. The medicament for treating stroke disease has the characteristics of invigorating the circulation of blood, tonifying qi, regulating vital energy, dredging main and collateral channels, dispersing blood stasis, relieving pain, clearing away heat and toxic materials, is suitable for the rehabilitation of assistant treatment of patients belongs to qi deficiency and blood stasis disease in the stroke disease recovery period, has remarkable curative effect, treatment on both symptoms and root causes, no toxic and side effects.