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Compound combination with taohongsiwu decoction used as source

A technology of Taohong Siwu Decoction and compounds, applied in the field of medicine, can solve the problems of unguaranteed efficacy and lack of experimental efficacy

Pending Publication Date: 2019-08-02
JINAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The curative effect of the existing Taohong Siwu Decoction lacks experiments to verify, so the effect cannot be guaranteed

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] The compound combination based on Taohong Siwu Decoction consists of quercetin (0.1mg), kaempferol (0.1mg), luteolin (0.1mg), myricetin (10mg), β-sitosterol (10mg), baicalin Vegetables (10 mg) were mixed to make compound combinations.

Embodiment 2

[0013] The compound combination based on Taohong Siwu Decoction consists of quercetin (0.5mg), kaempferol (6mg), luteolin (0.7mg), myricetin (7mg), β-sitosterol (6mg), baicalein (0.5 mg) were mixed to form compound combinations.

Embodiment 3

[0015] The compound combination based on Taohong Siwu Decoction consists of quercetin (10mg), kaempferol (10mg), luteolin (5mg), myricetin (0.1mg), β-sitosterol (0.1mg), baicalein (0.1 mg) were mixed to form compound combinations.

[0016] Baicalein has the functions of reducing vascular resistance, improving blood circulation and anti-platelet aggregation, and is often used to prevent and treat cardiovascular and cerebrovascular diseases such as hypertension. Studies have found that baicalein plays an important role in blood pressure, cardiac hypertrophy, fibrosis and inflammatory response in Ang II-induced hypertensive model mice. Some scholars have found that baicalein can alleviate MCT-induced pulmonary hypertension by inhibiting pulmonary artery wall thickening through experiments on rat models of pulmonary hypertension. Quercetin is one of the common flavonoids in plant foods, widely found in vegetables, fruits, wine and olive oil. Quercetin is associated with reducing...

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PUM

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Abstract

The invention discloses a compound combination with taohongsiwu decoction used as a source, and relates to the field of medicines. The compound combination with the taohongsiwu decoction used as the source is prepared by mixing quercetin (0.1-10 mg), kaempferol (0.1-10 mg), luteolin (0.1-5 mg), myricetin (0.1-10 mg), beta-sitosterol (0.1-10 mg) and baicalein (0.1-10 mg). Through systematic experiments, the therapeutic effects are proven.

Description

technical field [0001] The present invention relates to the field of medicine, and more specifically, the present invention relates to a compound combination based on Taohong Siwu Decoction. Background technique [0002] Taohong Siwu Decoction first appeared in the "Yi Zong Jin Jian" written by Wu Qian, a famous physician in the Qing Dynasty. It is one of the representative prescriptions for promoting blood circulation and removing blood stasis. It has the functions of promoting blood circulation, removing blood stasis, nourishing blood and promoting blood circulation, and is often used to prevent and treat cardiovascular related diseases. Clinical research also shows that Taohong Siwu Decoction, a prescription for promoting blood circulation and removing blood stasis, is widely used in the treatment of hypertension, which can improve the curative effect and prognosis. Analyzing the targets of Taohong Siwu Decoction in the prevention and treatment of hypertension through th...

Claims

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Application Information

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IPC IPC(8): A61K31/575A61K31/352A61P9/12
CPCA61K31/575A61K31/352A61P9/12A61K2300/00
Inventor 陈利国刘天浩陶文聪
Owner JINAN UNIVERSITY
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