The invention relates to medicated diet powder for adjusting human body sub-health. The medicated diet powder comprises medicine materials and food materials. The medicine materials comprise ginseng, cornua cervi pantotrichum, fleece-flower roots, boschniakia rossica, Maca, polygala tenuifolia, calamus, poria with hostwood, fructus alpiniae oxyphyllae, lucid ganoderma, the fruits of Chinese magnoliavine, raw hawthorn fruits, gastrodia elata, rhizome of rehmannia, radix ophiopogonis, angelica sinensis, acanthopanax roots, pearls, black sesame, fossil fragments and oyster. The food materials comprise millet, walnut kernels, Chinese dates and lotus seeds. The matching ratio of the medicine materials to the food materials is 1:3. The formula is the environment-friendly additive-free composition screened through a large number of experiments and capable of supplanting brain nutrition. The medicated diet powder has the quite good conditioning effect on the sub-health status of middle-aged and aged people. The medicated diet powder for adjusting human body sub-health can achieve the effects of tonifying primordial Qi, adding kidney essence, calming heart and tranquilizing the mind, tonifying brain and improving intelligence, strengthening tendons and bones, improving immunity, resisting dementia, softening blood vessels, lowering blood fat, lowering cholesterol, delaying ageing, prolonging life and the like.