230 results about "Hemorheology" patented technology

There is disclosed a miniature blood rheology measurement device and a blood rheology measurement method which are capable of performing measurement of a portion such as a wrist or a fingertip with a high precision and which are simple without requiring measurement of a blood pressure. The method: detects an artery blood flow rate, a pulsatile displacement, an artery diameter, an artery wall thickness, a heartbeat frequency, and a phase difference or an amplitude ratio of the blood flow rate and the pulsatile displacement, which change with elapse of time, by use of a sensor including ultrasonic wave transmitting and receiving elements for transmitting and receiving ultrasonic waves between the surface of a living body and an artery blood flow in the living body; and calculates a blood kinematic viscosity by use of one of the phase difference and the amplitude ratio, the blood vessel diameter, and the heartbeat frequency to obtain an index value of a blood rheology.

The invention relates to a DanShen fingerprint spectrum quality control method, comprising that (1), adding 1.0g DanShen powder into carbinol to extract via microwave, (2), washing flow phase gradient that the Alltima C18 column is 4.6mm, 250mm, and 5mum, checking wavelength is 280nm, flow speed is 1.0ml/min, the column temperature is 20-40Deg. C, and the sample amount is 10-20ul, (3), building standard fingerprint spectrum that the first peak is DanShen element, the eighth peak is rosmarinic acid, the ninth peak is alkannic acid, the tenth peak is phenolic acid B, the eleventh peak is phenolic acid B isomer, the fourteenth peak is cryptotanshinone and the fourteenth peak is tanshinone IIA, (4), controlling the quality of fingerprint spectrum that the check peak relative holding times are 0.21 of DanShen element, 0.91 of rosmarinic acid, 0.93 of alkannic acid, 1.00 of phenolic acid B, 1.04 of phenolic acid B isomer, 0.92 of cryptotanshinone and 1.00 of tanshinone IIA, (5), the DanShen planting collecting method. The invention can control the quality of materials to assure the stable quality of product.

The invention discloses a Chinese pharmaceutical composition for treating hepatitis and fatty liver, which comprises cornus officinalis, oriental wormwood, cape jasmine, baikal skullcap root, plantain seeds, clematis stem, polyporus umbellatus, poria cocos, rush pith, curcuma aromatica, licorice root, cyperus tuber, dandelion, white atractylodes rhizome, magnolia bark, Bupleurum root, chicken's gizzard-skin, green tangerine orange peel, banksia rose, malt, isatic root, haw, turtle shell, burred tuber, Loranthus mulberry mistletoe, talcum powder, bitter orange, zedoary, fleece-flower root, root of herbaceous peony, medicated leaven, Chinese angelica root, rhubarb horsetails.

The invention relates to a laguerre-gaussian beam-based speckle contrast imaging measurement device and a laguerre-gaussian beam-based speckle contrast imaging measurement method. The device comprises a continuous wave laser; after being reflected by a total reflective mirror, a light beam emitted by the continuous wave laser irradiates on a collimating beam expander; after that, the light beam becomes linearly polarized light by a polarizer and then irradiates on a beam splitting prism; after passing through the beam splitting prism, the light beam is divided into two beams, wherein one path is reflected light, and the other path is transmission light; the reflected light beam irradiates on a spatial light modulator, and the light beam reflected by the spatial light modulator irradiates on a diaphragm after passing through the beam splitting prism and an analyzer again; after passing through the diaphragm, the light beam irradiates on a sample to be tested; after being scattered by the sample to be tested, the light beam is converged by an imaging lens, and then an image is formed in a charge coupled device (CCD) camera; after that, the image is stored in a computer, and the image contrast value can be calculated; when a light path is difficult to adjust, the speckle size is adjusted by changing the characteristics of the illumination beam, so that the method has the characteristics of being flexible and reliable; the method is widely applied to the fields such as hemorheology monitoring, plant growth condition monitoring, etc.

The invention discloses a vacuum test tube which comprises a vacuum tube containing hirudin as anticoagulant therein. The hirudin can be in the form of freeze-dried powder or spray-dried powder or aqueous solution, or modified with polyethylene glycol or encapsulated in liposome. The content of the hirudin in the vacuum tube is 100-2000 ATU per milliliter of blood. The hirudin has an amino acid sequence (see sequence 1 in the sequence table). The vacuum test tube of the invention is used in clinical biochemistry, clinical immunology, clinical hemorheology, immune prototype analysis, RT-PCR detection and clinical hematological examinations (except cruor parameters) and realizes versatility of laboratory examinations.

The invention relates to a medicinal mixture for treating cardiovascular diseases, which comprises (by weight portions) ginger extract 100 and dried orange peel extract 1-100 mainly containing ginger volatile oil, gingerol and dried orange peel volatile oil.

A method for the removal of cholesterol, triglycerides and other lipids from animal plasma, serum or other suitable blood fractions, as a discontinuous flow system, the method comprising withdrawing blood from a subject, separating the required fraction from the blood and mixing with a solvent mixture which extracts the lipids from the fraction, after which the delipidated fraction is recombined with the blood cells and returned to the subject, wherein the solvent extraction step is carried out separately and remote from the subject. The delipidated fraction is washed with a second solvent before being recombined with the blood cells. To ensure that the delipidated fraction is free from all extraction solvent, the fraction is mixed with an absorbent specific for the solvent that is being removed. The preferred absorbent is a macroporous polymeric bead contained in the pores of a sintered glass or plastic sphere, the being capable of absorbing organic molecules from an aqueous solution. By treating the plasma, serum or other suitable blood fraction of a patient by these methods, the blood rheology of a patient with impaired blood circulation can be improved. Further, a rapid regression of coronary atherosclerosis occurs.

A blood rheology measurement device and a blood rheology measurement method which detect a fingerprint or a vein to thereby measure a positional relation between an artery in a living body and a sensor on the same conditions for each subject during non-invasive measurement and which correctly evaluate a change of blood rheology with elapse of time. A vein pattern or a fingerprint pattern peculiar to a subject is detected, recognized, and stored, a position of a sensor is adjusted so that the detected vein pattern or fingerprint pattern agrees with the stored vein pattern or fingerprint pattern every measurement, and a blood rheology index value indicating blood fluidity (fluidity/viscosity) is measured.

The invention relates to a schisandra fruit fingerprint spectrum quality control method, comprising that (1), adding 0.5g schisandra fruit to extract via microwave for 50min, filtering, (2), washing flow phase gradient that the spectrum column is Eclipse, as 0-40min, 60-20% A, 40-80% B, flow speed is 0.8-1.2ml/min, the wavelength is 210-280nm, the column temperature is 20-40Deg. C, and the sample amount is 10-20ul, (3), building standard fingerprint spectrum that the first peak is schisandra fruit alcohol 1, the third peak is schisandra fruit alcohol 2, the fourth peak is gemixin N/ isomer, the sixth peak is schisandra fruit I element, the seventh and eighth peaks are gemixin N/ isomer, the ninth peak is schisandra fruit II element, (4), controlling the quality of fingerprint spectrum that the check peak relative holding times are 1.00, 1.25, 1.63, 1.88, 3.18 and 3.27, (5), the schisandra fruit planting collecting method. The invention can control the quality of materials to assure the stable quality of product.

An application of the Chinese medicine prepared from red sage root, notoginseng and borneol in preparing the medicines for treating multi-organ injury caused by metabolic syndrome is disclosed.

The invention discloses a non-invasive detecting method for blood viscosity based on pulse wave, and belongs to the fields of biomechanics and hemorheology. The method is characterized by comprising the following steps of: detecting the pressure pulse wave of a radial artery by using a pressure sensor to realize non-invasive detection of the blood viscosity, establishing a relation among the pulse wave of the radial artery, pressure gradient and blood flow, and solving an ordinary differential equation to obtain a numerical solution of the blood flow at different moments in a cardiac cycle; and establishing a relation between the blood flow and the blood viscosity, and thus obtaining the blood viscosity. Meanwhile, by the method, personalized calculation can be realized, and the pain of patients can be furthest relieved; and the detecting method is simple and convenient, is beneficial to promoting universal and popular development of blood viscosity detection, and finally realizes early prediction and clinical diagnosis functions of certain hemodynamic diseases.

A process and equipment for purifying blood includes such steps as centrifugal separation of blood cells from blood plasma, and removing fat from blood plasma through condensing, thawing, Ca ion inducing, freezing, warm dissolving and depositing, radiating the plasma by ultraviolet ray and laser quantum in vibration and stirring state while magnetizing and aerating. It can improve the rheopectic nature and lalance effect of blood.

The invention relates to a pharmaceutical composition for treating chronic stable angina pectoris with hyperlipermia, which comprises the components of a drug carrier, a sino atrial node If current selective specificity inhibitor or pharmaceutical salt thereof, and an HMG-CoA reductase selective depressant or pharmaceutical salt thereof; the sino atrial node If current selective specificity inhibitor or the pharmaceutical salt thereof is Ivabradine hydrochloride; and the contents of the components of the medical composition by mass unit are 2.5 to 10 of the sino atrial node If current selective specificity inhibitor and 2.5 to 100 of the HMG-CoA reductase selective depressant. The medical composition has good synergistic effect when treating the chronic stable angina pectoris with the hyperlipermia, and has good effect of lowering hyperlipemia for hyperlipoidemia and hemorheology effect.

The present invention discloses a diabetic peripheral neuropathy treatment traditional Chinese medicine composition, which is prepared mainly from the following bulk drugs, by weight: 10-50 parts of milkvetch root, 5-20 parts of angelica tail, 3-18 parts of szechwan lovage rhizome, and 6-24 parts of red peony root. The traditional Chinese medicine composition further comprises the following bulk drugs, by weight: 10-30 parts of common achyranthes, 6-24 parts of dan-shen root, 2-15 parts of safflower, 5-20 parts of peach seed, 6-24 parts of leech, 10-30 parts of rehmannia dride rhizome, and 10-30 parts of pubescent holly root. With application of the traditional Chinese medicine composition to treat the diabetic peripheral neuropathy, clinical symptoms can be improved, blood rheology indexes can be improved, and motor nerve conduction velocity and sensory nerve conduction velocity can be increased.

The invention provides a traditional Chinese medicine composition for treatment of chronic renal diseases and chronic renal failure and its preparation method. The traditional Chinese medicine composition is prepared from the following raw material medicines by weight: 6-40 parts of rheum officinale, 10-95 parts of astragalus and 5-65 parts of salvia miltiorrhiza by a certain extraction and purification process into an injection, a freeze-dried powder injection or other oral preparations. Animal experiments confirm that, the traditional Chinese medicine composition can obviously improve the hemodynamic indexes of rats subjected to chronic glomerulonephritis, reduces serum IL-6, IL-8, and TNF (tumor necrosis factor)-alpha levels, significantly reduces serum creatinine and urea nitrogen and other indexes of rats subjected to hypertensive nephropathy, significantly reduces serum urea nitrogen and serum creatinine contents of rats subjected to the chronic renal failure, increases serum albumin content, and also can improve each hemodynamic index of rats subjected to the chronic renal failure; and pathological results show that the traditional Chinese medicine composition can improve and inhibit injures on kidney caused by the chronic renal diseases and chronic renal failure.

The invention discloses a sampling apparatus of a hemorheology instrument. The inner end of a lifting arm penetrates through one guide groove to extend into a lifting support and is connected with a driving mechanism, and a light blocking plate is arranged on the lifting arm and is matched with a groove-shaped photoelectric switch. Multiple sampling needles penetrating through a needle cleaning device are arranged at the outer end of the lifting arm. A dividing plate is coaxially arranged under a test tube turntable, slotted holes are formed in the dividing plate, a level gauging through hole is formed beside one slotted hole, a main photoelectric switch matched with the corresponding slotted hole is arranged besides the dividing plate, and an auxiliary photoelectric switch matched with the level gauging through hole is formed. The sampling apparatus of the hemorheology instrument has the advantages that the mode that the multiple sampling needles work simultaneously is adopted, the working efficiency of the single hemorheology instrument is greatly improved, and the cost is saved as a whole. In addition, the accuracy and stability of the hemorheology instrument in the working process are greatly improved by matching the photoelectric switches with the lifting arm and the test tube turntable for usage.

The invention provides a hemorheology detector with a cleaning function for detecting the blood viscosity. The hemorheology detector comprises a collected sample, a cleaning pump, a three-way valve, cleaning liquid, a pressure sensor and a central processor, wherein one end of a detection end pipeline is arranged at the upper part of the collected sample, and the other end of the detection end pipeline is mounted at one end of a detection warehouse; the pressure sensor is arranged in the detection warehouse; the signal transmission end of the pressure sensor is connected with the signal transmission end of the center processor; the other end of the detection warehouse is connected with a pump group; the pump group is used for vacuumizing or pressurizing the detection warehouse; the other end of the detection warehouse is connected with one end of the cleaning pump; the other end of the cleaning pump is connected with the output end of the three-way valve; the input end of the three-way valve is arranged into the cleaning liquid. The hemorheology detector realizes automatic cleaning in a blood viscosity detection process, and is convenient and quick.

The invention provides a Chinese medicinal composition for preventing and treating cardiovascular and cerebrovascular diseases and resisting fatigue, which comprises the following components in part by weight: 30 to 90 parts of glossy ganoderma extract, 40 to 120 percent of notoginseng root extract, 40 to 120 parts of root of red-rooted salvia extract and 40 to 120 parts of ginkgo leaf extract. The Chinese medicinal composition has the effects of regulating blood fat, improving hemorheology and resisting atherosclerosis, anoxia and fatigue, can reduce the level of lactic acid and serum urea and can relieve the discomfort feeling of limb weakness, oscitancy, muscular soreness, anorexia and the like which are caused by sports effectively. The invention also provides a Chinese medicinal preparation containing the Chinese medicinal composition and a preparation method thereof.

The invention is a medicine for curing arthrolithiasis and the preparing method thereof, characterized by that it is prepared of White Paeony Root, Fenbixian, Mulberry Twig, Herba Siegesbeckiae, Coix Seed, Glabrous Greenbrier Rhizome, Medicinal Cyathula Root, Clematis Root, and Membranous Milkvetch Root in certain proportion and able to be made into any oral form. It has functions of clearing heat and discharging corruption, tonifying spleen and promoting diuresis, and dispelling the wind and removing rheumatism and is used for curing diseases caused by damp, heat, accumulation and mass, especially pains in limbs, muscles and veins, red and swelling, fever and pains of joint, and inconvenient bending and extending. The curative effect study verifies that it can reduce the uric acid content of the blood serum of an animal with high- uric acid content blood disease, improve rheological indexes of the blood, and treat gouty arthritis and common inflammation and has good pain-stopping function and very curative effect on acute and chronic grouts, where the clinical effective rate is up to 91.36%.

The invention relates to a traditional Chinese medicine composition preventing and curing cardiovascular and cerebrovascular diseases. With milkvetch roots being principal herbs, the composition of salvia roots, ginkgo leaves and pseudo-ginseng in a specific proportion has the obvious effect of preventing and curing the cardiovascular and cerebrovascular diseases, can obviously reduce blood lipid of rats with hyperlipemia, has the obvious effect of restraining artery, vein and vein bypass thrombus and can improve hemorheology, restrain ear swelling caused by xylene and inflammatory reaction caused by cotton ball granuloma and obviously prolong survival time of the rats which are suffered from normal-pressure hypoxia tolerance, sodium nitrite poisoning and acute cerebral ischemic anoxia. In this way, the hypoxia tolerance capacity of organisms is improved, and the traditional Chinese medicine composition has a certain effect of protecting myocardial ischaemia injuries and cerebral injuries, and is free of acute toxicity, genetic toxicity and chronic toxicity and suitable for preventing and curing the cardiovascular and cerebrovascular diseases.

A traditional Chinese medicine composition for whitening skin relates to the technical field of Chinese herbal medicine, and comprises the following raw herbs by weight: 19-21 g of donkey-hide gelatin, 14-16 parts of longan aril, 19-21 g of lemons, 19-21 g of coix seeds, 14-16 g of scutellaria, 14-16 g of medlar, 19-21 g of haws, 11-13 g of peach seeds, 14-16 g of Chinese yam, 14-16 g of mulberries, 11-13 g of tangerine peel, 14-16 g of polygonatum rhizome, and 19-21 g of jujube. The composition of the invention is prepared from various Chinese herbal medicines, can dredge channels and collaterals, replenish qi, nourish blood, disperse blood stasis, tonify kidney, invigorate blood circulation, tonify deficiency, reduce excess, soothe liver, attain mental tranquility, dynamically balance the whole internal organs, relieve endocrine disorder, and improve hemorheological indexes, combines regulation with nourishing, and has the characteristics of convenient administration, and low drug-taking cost.

Effect of medical glue blood-nourishing on freckle removal, senescence resistance and increment of skin nutrition relates to the new use of the medical glue blood-nourishing syrup. The medical glue blood-nourishing syrup has effects on freckle removal, senescence resistance and increment of skin nutrition and can be used for female beauty treatment. Henan Hongxin Medicine Science Research Institute performs influence test of luteosterone induced freckle model mouse, the influence test of luteosterone D-galactose induced senescence model mouse, the influence test of polar blood stasis model rat hemorheology and the influence test of mouse auricle circulation, and the tests show that the medical glue blood-nourishing syrup has obvious effects on freckle removal, senescence resistance and increment of skin nutrition. The effects are associated with the functions that the medical glue blood-nourishing syrup inhibits generation of melanin, removes free radicals, accelerates synthesis of collagen, and improves hemorheology and microcirculation.

The invention discloses a hemorheology detecting device. The hemorheology detecting device comprises a main support, a centrifugal rotating disc and a centrifugal motor. The centrifugal rotating disc is installed on a main shaft of the centrifugal motor. The hemorheology detecting device further comprises a stepping motor. A main shaft of the stepping motor drives the centrifugal rotating disc to rotate by a certain angle after centrifuging is finished. The hemorheology detecting device is characterized in that after centrifuging is finished, the main shaft of the stepping motor drives the main shaft of the centrifugal motor to drive the centrifugal rotating disc to rotate by the certain angle. A mechanism for driving the sample disc to be positioned is simple in structure, and the arrangement of a sampling device can not be influenced.

The invention belongs to the technology field of traditional Chinese medicine, in particular to a traditional Chinese medicine for activating blood circulation, dredging vessels and benefiting wisdom which is used for the treatment of vascular dementia, thus solving the problems of limited efficacy, severe toxicity and side effects and expensive cost of the medicine for the treatment of vascular dementia in the prior art. The traditional Chinese medicine for activating blood circulation, dredging vessels and benefiting wisdom which is used for the treatment of vascular dementia takes grassleaf sweelflag rhizome, danshen root, tuber fleeceflower root, membranous milkvetch root, Chinese angelica, wild hawthorn fruit and epimedium herb as sovereign medicines. Tall gastrodia tuber, cassia seed, oriental waterplantain rhizome, kudzuvine root and stewed rhubarb are taken as auxiliary materials. The medicine of the invention can improve the memory, know the symptoms, or have certain efficacies on the aspects of spirit antagonism and behavior obstacles, regulate blood pressure, blood lipids, blood glucose and blood rheology, inhibit peroxide substances, improve neurotransmitter conduction and free radical metabolism and have the inhibition of the development of vascular sclerosis, so the medicine can be used for the prevention and the treatment of vascular dementia.

The present invention discloses a Chinese medicine for effectively curing salpingitis with obvious therapeutic effect. Said Chinese medicine is made up by using 8 Chinese medicinal materials of Chinese angelica root, ligusticum root, zedoary, forsythia fruit, prunella spike, liquidambar fruit and others through a certain preparation process.

The invention relates to joint synergy of ferulic acid and matrine alkaloid and a medical application thereof. A compound comprising ferulic acid and matrine alkaloid can obviously improve the pharmaceutical effect of the ferulic acid and/or the matrine alkaloid, can exist in a compound mode of sophora and angelica and/or hemlock parsley and asafetida extractive or can be a compound formed by monomeric compounds of the ferulic acid and/or the matrine alkaloid. The invention has anti-organ fibrosis action, hemorheology improvement, antiviral action, inflammatory action, cholinesterase inhibitory action, analgesic and antipruritic action, antithrombotic action, anti-platelet aggregation action, antibacterial action, antitumor action, oxidation-resistant action, hypolipemic action, immunity enhancement, sperm activity and motion stimulation, antihypertensive action, and the like which are obviously better than the single action of the ferulic acid or the matrine alkaloid.