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5 results about "Blood fluidity" patented technology

Expandable polymeric heart valve

PCT designated stageWO2025236506A1Heart valvesBlood fluidityBlood flow
The present invention provides an expandable polymeric heart valve. The expandable polymeric heart valve comprises valve leaflets and a valve frame, the valve frame being a hollow columnar structure. The valve further comprises an insert, the insert being adapted to be embedded in the valve frame along an axial direction. At least one expansion slot is circumferentially formed on the insert, the expansion slot having a closed state and an open state. An outer wall of the insert at both ends of the expansion slot is provided with a limiting structure, the limiting structure defining an expansion width when the expansion slot is in the open state. When the expansion slot is in the closed state, a cross-section of the insert presents as a closed ring, the insert has a first diameter, and the heart valve is in an original state for normal use, allowing blood to flow unidirectionally. When the expansion slot is in the open state, the cross-section of the insert presents as a circular ring with an opening, the insert has a second diameter greater than the first diameter, and the heart valve is in an expanded state, allowing for valve-in-valve implantation. The present invention achieves expandability of the valve after damage, while ensuring the blood flow performance of the valve in the original state during normal use.
Owner:SUZHOU HEARTHILL MEDICAL CO LTD

A non-invasive real-time detection method, system and wearable device for blood blockage recovery time

The application discloses a non-invasive real-time evaluation method and system for blood fluidity and a wearable device, and belongs to the technical field of biomedical signal processing and intelligent health monitoring. The method comprises the following steps: acquiring an event timestamp of a blood blocking device and a physiological signal of a blood health measurement module; automatically intercepting a signal segment of a recovery stage based on the event timestamp; parallelly calculating a plurality of independent indexes characterizing the recovery process; performing validity checking on each index, and eliminating invalid or abnormal candidate values; and outputting a final recovery time after blocking by using a dynamic adaptive fusion strategy. The application further discloses a detection system and a wearable device for realizing the method. The application uses recovery kinetics after pressure relief to represent blood fluidity, realizes automatic and accurate detection of the recovery time through a multi-index cooperative judgment and a dynamic fusion mechanism, effectively suppresses noise interference and improves robustness, and can be used for non-invasive evaluation of vascular elasticity, blood viscosity and microcirculation function.
Owner:SHANGHAI JIAOTONG UNIV

Composition for improving diabetes accompanied by cerebrovascular diseases as well as preparation method and application of composition

The invention provides a composition for improving diabetes with cerebrovascular diseases and a preparation method and application thereof, and relates to the technical field of traditional Chinese medicines. The composition is prepared from the following raw materials in parts by weight: 100 to 150 parts of radix puerariae, 20 to 40 parts of radix angelicae sinensis, 30 to 50 parts of radix paeoniae rubra, 15 to 25 parts of rhizoma chuanxiong, 10 to 20 parts of rhizoma pinellinae praeparata, 8 to 13 parts of radix glycyrrhizae preparata, 15 to 26 parts of radix asparagi, 30 to 50 parts of rhizoma coptidis and 15 to 27 parts of pericarpium trichosanthis. The radix puerariae, the radix angelicae sinensis, the rhizoma coptidis and the pericarpium trichosanthis are extracted with ethanol, medicine residues are decocted with other components, and the obtained composition has the effect of improving the symptoms of diabetes with cerebrovascular diseases and can reduce the blood sugar level and the content of inflammatory factors; the blood mobility is obviously improved, and the recognition capability on new things is improved; the sleep latency period and the average respiratory rate are reduced, and the symptoms of dizziness, palpitation, annoyance and dizziness in chest and hypochondrium fullness are improved. The composition is applied to preparation of drugs for improving diabetes with cerebrovascular diseases, and the effect is remarkable.
Owner:BEIJING SUPREME PHARM TECH CO LTD

Blood perfusion device

The utility model discloses a hemoperfusion device, relates to the technical field of blood purification, it includes the cylinder, be provided the inlet end cover and the outlet end cover of cylinder both ends respectively, and heating device, the heating device is used for raising the temperature in the cylinder and maintains at the specified temperature, the utility model provides a hemoperfusion device. When treatment is carried out, the heating device is turned on to heat the interior of the cylinder body and maintain the temperature at the specified temperature, so that the conditions of viscosity increase and fluidity reduction caused by temperature reduction of blood are avoided, the risk of blood coagulation is reduced, meanwhile, the conditions of hypothermia are reduced, and the problems that the viscosity increase of the blood is caused by temperature reduction and the fluidity of the blood is reduced are solved. The problem that the treatment effect is affected due to reduction of the adsorption surface area of resin microspheres caused by mutual adhesion of the resin microspheres after the resin microspheres in the perfusion device are in contact with the blood is solved.
Owner:SHANDONG WEIGAO BLOOD PURIFICATION PRODUCTS CO LTD

A deer blood peptide for improving qi deficiency and blood stasis, and a preparation method and application thereof

PendingCN122629158ABiotechnologyMetabolite
This invention discloses a deer blood peptide for improving qi deficiency and blood stasis, its preparation method, and its application, belonging to the field of functional peptide technology. The deer blood peptide prepared using the method provided by this invention has a molecular weight of less than 3000 Da, making it easily absorbed and utilized by the body, and exhibiting high bioactivity. While obtaining the low molecular weight deer blood peptide, it can also effectively release heme, achieving a rapid blood-replenishing effect. It also contains small-molecule unsaturated fatty acids, which help lower blood lipids and improve blood flow, theoretically having a good effect on improving qi deficiency and blood stasis. Experimental results also show that the prepared deer blood peptide alone can effectively improve qi deficiency and blood stasis. It can effectively avoid the toxic side effects of harmful bacteria and their metabolites; it has a high yield and good flavor; it is simple and easy to operate, with mild conditions and low equipment requirements; it has high safety and is environmentally friendly; it produces no by-products, has low preparation costs, and high bioavailability of the material.
Owner:HAINAN HUAYAN MEIJIAN BIOTECHNOLOGY CO LTD +1