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Ginger and dried orange peel extracts mixture for treating cardiovascular disease

A technology of tangerine peel extract and ginger extract, which is applied in the direction of cardiovascular system diseases, drug combinations, plant raw materials, etc., can solve the problems of no further breakthrough, can not solve the problem of atherosclerosis, etc., achieve clear effective parts, improve blood flow The effect of variable science and simple production process

Inactive Publication Date: 2006-02-08
GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are hundreds of traditional Chinese medicines used to treat cardiovascular diseases, no further breakthroughs have been made because they cannot solve the problem of atherosclerosis pharmacologically.

Method used

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  • Ginger and dried orange peel extracts mixture for treating cardiovascular disease
  • Ginger and dried orange peel extracts mixture for treating cardiovascular disease
  • Ginger and dried orange peel extracts mixture for treating cardiovascular disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-1

[0036] Embodiment 1-1: the preparation of ginger, tangerine peel extract mixture

[0037] Weigh 10kg of raw ginger that has been pre-dried and crushed to a particle size below 1mm, put it into the extraction kettle, and feed it with supercritical CO 2 The fluid is extracted at 25MPa and 35°C for 1 hour; the extract enters the separation tank and is separated at 10MPa and 50°C for 1 hour to obtain ginger supercritical CO 2 Extract. Weigh 10 kg of dried tangerine peel medicinal powder, distill it with steam for 5 hours, collect the distillate, and separate the oil and water to obtain the volatile oil extract of tangerine peel. Mix according to the weight ratio of ginger extract: tangerine peel extract=100:100 to obtain the ginger and tangerine peel extract mixture.

Embodiment 1-2

[0038] Embodiment 1-2: the preparation of ginger, tangerine peel extract mixture

[0039] Weigh 10kg of raw ginger that has been pre-dried and crushed to a particle size below 1mm, put it into the extraction kettle, and feed it with supercritical CO 2 The fluid is extracted at 15MPa and 40°C for 0.5 hours; the extract enters the separation tank and is separated at 15MPa and 40°C for 2 hours to obtain ginger supercritical CO 2 Extract.

[0040] Weigh 5 kg of coarse powder of tangerine peel medicinal material, distill it with water steam for 8 hours, collect the distillate, and separate the oil and water to obtain the volatile oil extract of tangerine peel. Mix according to the weight ratio of ginger extract: tangerine peel extract=100:50 to obtain the ginger and tangerine peel extract mixture.

Embodiment 1-3

[0041] Embodiment 1-3: the preparation of ginger, tangerine peel extract mixture

[0042] Weigh 10kg of raw ginger that has been pre-dried and crushed to a particle size below 1mm, put it into the extraction kettle, and feed it with supercritical CO 2 The fluid is extracted at 30MPa and 25°C for 2 hours; the extract enters the separation tank and is separated at 8MPa and 60°C for 0.5 hours to obtain ginger supercritical CO2 Extract.

[0043] Weigh 10 kg of dried tangerine peel medicinal material coarse powder, distill with water steam for 3 hours, collect the distillate, and separate the oil and water to obtain the volatile oil extract of tangerine peel. Mix according to the weight ratio of ginger extract: tangerine peel extract=100:0.1 to obtain the ginger and tangerine peel extract mixture.

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PUM

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Abstract

The invention relates to a medicinal mixture for treating cardiovascular diseases, which comprises (by weight portions) ginger extract 100 and dried orange peel extract 1-100 mainly containing ginger volatile oil, gingerol and dried orange peel volatile oil.

Description

technical field [0001] The invention relates to a mixture of ginger and tangerine peel extracts for treating cardiovascular diseases. Specifically, a mixture of extracts made from the rhizome of Zingiberaceae plant ginger (Zingiber offfficinale Rosc) and the mature peel (tangerine peel) of Rutaceae plant orange (Citrus reticulata Blanco) cultivar, is especially suitable for preparing anti-myocardial ischemia , antithrombotic, blood lipid lowering, blood pressure regulation, anti-atherosclerosis related drugs. Background technique [0002] Cardiovascular disease is one of the major diseases that threaten human beings. Although the mortality rate of cardiovascular disease has declined to varying degrees in most countries except Eastern European countries in the past 30 years, it is still the first cause of death among men over 45 years old in most countries. The cause of death is the second cause of death after tumors in women, which seriously affects the life expectancy and ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P9/00A61P9/10
Inventor 王宁生
Owner GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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