8results about How to "Improve research" patented technology

The application relates to the field of noise reduction technology and discloses a spiral acoustic black hole noise reduction module and a design method thereof, which comprises a shell layer, an acoustic black hole cavity and a neck pipe; the shell layer is used for wrapping the acoustic black hole cavity to form a closed space; the acoustic black hole cavity comprises an acoustic black hole cavity plate curved according to an Archimedes spiral line and a rib plate array; the neck pipe is arranged at the rotation center position of the spiral line track of the acoustic black hole cavity plate, and the neck pipe is a sound wave incidence pipe; the rib plate array comprises a plurality of rib plates arranged in an increasing or decreasing length; one end of each rib plate is fixed to the inner side of the acoustic black hole cavity plate, and the other end is a free end; the rib plates are arranged at equal arc lengths / distances, and the lengths are arranged in a monotonically decreasing or increasing rule to form an acoustic black hole structure. The application realizes the sound absorption effect of ultralow frequency with a small size, reaches a sound absorption peak under specific frequency, and enhances the sound absorption effect of the sound absorption device in a specific frequency band.

The application discloses a key amino acid induced new crystal form of linagliptin based on protein-drug interaction structure mining and a preparation method thereof; and the technical scheme is that key amino acids are introduced into a solvent crystallization system of linagliptin to induce five new crystal forms of linagliptin; the preparation method does not need to use a large amount of organic solvents, has the characteristics of being simple, precise and efficient, has strong crystal form regulation capacity, is energy-saving, environment-friendly and safe, and is easy to realize green industrial production.

The application discloses a kind of based on physical information neural network's fault rolling bearing angular domain model construction method and system, method includes: the instantaneous angular displacement sequence and the encoder instantaneous angular velocity signal collected to physical information neural network is input, the initial value of setting dynamics parameter;Bearing dynamics model is embedded in the training process of network, solve the angular variable vibration displacement of fault bearing three degrees of freedom angular domain dynamics equation group, calculate disturbance torque;Physical loss is constructed;The residual of actual IAS is used as true value loss, and the overall loss is calculated in combination with physical loss;The accurate estimation value of dynamics parameter is obtained by network, it is input into the IAS response under different fault types and working conditions in fault bearing dynamics model;The expansion of the sample of fault diagnosis data set sample is completed using the generated sample obtained. It is used to improve the imbalance intelligent diagnosis problem that normal sample amount is far more than fault sample under actual working condition, and the IAS signal sample of fault bearing is supplemented.

A fault-tolerant verification system and method supporting software and hardware fault injection and voting, wherein the fault-tolerant verification system supporting software and hardware fault injection and voting comprises fault injection management software, a power management module, a fault injection device, a simulation device and an entity device. The fault-tolerant verification method supporting software and hardware fault injection and voting is performed by means of the above system. A suitable fault model is established, and meanwhile, it is ensured that the faults of the verification system will not cause damage to the real device.

This invention belongs to the field of fluorescent and antibacterial carbon nanomaterials technology, specifically relating to a method for preparing and applying fluorescent carbon quantum dots using apigenin as the carbon source. Apigenin powder is dispersed in a 0.01-1M KOH solution via ultrasonic dispersion, then transferred to a high-pressure reactor for hydrothermal reaction. After heating, the mixture is naturally cooled to room temperature. The reaction product is then filtered and freeze-dried to obtain apigenin carbon quantum dot powder. The obtained apigenin carbon quantum dots exhibit antibacterial properties against Staphylococcus aureus and Escherichia coli under ultraviolet light irradiation. This invention offers a low-cost and simple method, producing carbon quantum dots with strong luminescence, good water solubility, stable luminescence at alkaline pH, and highly efficient photodynamic antibacterial properties, showing broad application prospects in the biological field.

This invention discloses a 6K liquid-phase breeding chip for broccoli, its dedicated single nucleotide polymorphism (SNP) variant sites, and its applications. The 6K liquid-phase breeding chip provided by this invention includes a probe combination for detecting 5971 SNP variant sites in the broccoli genome. The location information of the probe corresponding to each SNP variant site in the broccoli reference genome is shown in Table 3 of the specification. The SNP variant sites involved in the liquid-phase breeding chip provided by this invention have advantages such as high polymorphism, good repeatability, stable and reliable labeling, and ease of statistical analysis. This invention can also establish a DNA fingerprint database based on the liquid-phase breeding chip for identifying the authenticity of broccoli varieties. It can be used for identifying the authenticity of broccoli varieties, early breeding and identification of broccoli varieties, identification of broccoli seed resources, and provides technical support for enriching broccoli germplasm resources, breeding new varieties, and protecting new varieties, with broad application prospects.

The application discloses a nimodipine crystal form and an inducing method thereof, and has the technical scheme that a trace amount of an organic solvent is added into nimodipine, grinding beads with different diameters are put into the nimodipine, the crystal form is induced and changed by grinding, and a new crystal form is obtained after drying; the method controls the material and size of the grinding beads, adjusts the kinetic process of the crystal form change, and remarkably improves the purity and stability of the target crystal form; the amount of the organic solvent used is extremely low, the green pharmaceutical principle is met, the process is simple, the repeatability is good, and the method is suitable for industrial production.

This invention discloses a method for producing toxic proteins and its applications, belonging to the fields of genetic engineering and biotechnology. The method includes: constructing a fusion expression vector containing a domain capable of mediating biomolecular phase separation and an antimicrobial peptide gene; transforming the fusion expression vector into *Corynebacterium glutamicum*, culturing the transformed *Corynebacterium glutamicum* to express the fusion protein and form a membraneless organelle; collecting the cultured bacterial cells and extracting the antimicrobial peptide. This invention utilizes the principle of biomolecular phase separation, isolating the antimicrobial peptide from the host cell by forming a membraneless organelle, effectively increasing the expression level of the antimicrobial peptide in *Corynebacterium glutamicum*. This method can be applied to the production of various antimicrobial peptides.