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The application discloses a kind of based on physical information neural network's fault rolling bearing angular domain model construction method and system, method includes: the instantaneous angular displacement sequence and the encoder instantaneous angular velocity signal collected to physical information neural network is input, the initial value of setting dynamics parameter;Bearing dynamics model is embedded in the training process of network, solve the angular variable vibration displacement of fault bearing three degrees of freedom angular domain dynamics equation group, calculate disturbance torque;Physical loss is constructed;The residual of actual IAS is used as true value loss, and the overall loss is calculated in combination with physical loss;The accurate estimation value of dynamics parameter is obtained by network, it is input into the IAS response under different fault types and working conditions in fault bearing dynamics model;The expansion of the sample of fault diagnosis data set sample is completed using the generated sample obtained. It is used to improve the imbalance intelligent diagnosis problem that normal sample amount is far more than fault sample under actual working condition, and the IAS signal sample of fault bearing is supplemented.

This invention belongs to the field of fluorescent and antibacterial carbon nanomaterials technology, specifically relating to a method for preparing and applying fluorescent carbon quantum dots using apigenin as the carbon source. Apigenin powder is dispersed in a 0.01-1M KOH solution via ultrasonic dispersion, then transferred to a high-pressure reactor for hydrothermal reaction. After heating, the mixture is naturally cooled to room temperature. The reaction product is then filtered and freeze-dried to obtain apigenin carbon quantum dot powder. The obtained apigenin carbon quantum dots exhibit antibacterial properties against Staphylococcus aureus and Escherichia coli under ultraviolet light irradiation. This invention offers a low-cost and simple method, producing carbon quantum dots with strong luminescence, good water solubility, stable luminescence at alkaline pH, and highly efficient photodynamic antibacterial properties, showing broad application prospects in the biological field.

The application discloses a nimodipine crystal form and an inducing method thereof, and has the technical scheme that a trace amount of an organic solvent is added into nimodipine, grinding beads with different diameters are put into the nimodipine, the crystal form is induced and changed by grinding, and a new crystal form is obtained after drying; the method controls the material and size of the grinding beads, adjusts the kinetic process of the crystal form change, and remarkably improves the purity and stability of the target crystal form; the amount of the organic solvent used is extremely low, the green pharmaceutical principle is met, the process is simple, the repeatability is good, and the method is suitable for industrial production.