154results about How to "Have toxic side effects" patented technology

The invention discloses a nutritional type high slow release performance compound fertilizer for planting rice. The nutritional type high slow release performance compound fertilizer comprises the raw materials of urea, monoammonium phosphate, potassium chloride, ammonium chloride, diammonium hydrogen phosphate, monocalcium phosphate, zinc sulfate, ammonium molybdate, magnesium sulfate, oyster shell powder, kieselguhr, modified sepiolite powder, kaolin powder, talcum powder, dolomite powder, zeolite powder, thiourea, dicyandiamide, chicken manure, cicada manure, wormcast, maize straw, rapeseed cake, bagasse, coal ash, perilla seed, humic acid, EM strain, lignin and a modified slow-release inhibitor. The invention further provides a preparation method of the nutritional type high slow release performance compound fertilizer. The prepared compound fertilizer has an excellent slow release performance, provides rich nutrient substances for the crop, promotes the growth of the crop, and improves the yield and the quality of the crop.

The invention discloses a redox-sensitive core-crosslinked Pulullan nano particle having dual-targeting property and a preparation method thereof, preparation of a drug carrying nano particle with the compound as a carrier, and in-vitro releasing researching of the drug carrying nano particle. The method includes the steps of: 1) performing esterification reaction to lipoic acid and Pulullan to convert the water-soluble Pulullan into a hydrophobic polymer, which is beneficial to preparation of nano particles and entrapment of a hydrophobic medicine; 2) conjugating the polymer with folic acid to form a folic acid-Pulullan-lipoic acid conjugate, and performing crosslinking to inner cores of the nano particles in DTT in catalytic quantity to prepare stable and reversible folic acid-Pulullan-lipoic acid (FA-Pull-LA) nano particles having dual-targeting property. The drug carrying nano particle is prepared with paclitaxel as a model medicine in a dialysis manner, wherein stability and reduction sensitivity of the drug carrying nano particle are inspected through an in-vitro releasing test. A result proves that the dialysis method for preparing the FA-Pull-LA nano particles is simple and has good repeatability, is easy to achieve expanded production and has high drug carrying rate. The nano particle is stable in vitro and can quickly release the drug in an intracellular reductive environment.

The invention discloses a fish compound traditional Chinese medicinal preparation prepared from raw materials including rhubarb, acanthopanax, radix astragali, hawthorn and liquorice according a certain weight ratio. A method for preparing fish compound traditional Chinese medicinal preparation comprises the following steps of: A. washing and drying the rhubarb, the acanthopanax, the radix astragali, the hawthorn and the liquorice in the sun; B. respectively crushing and sieving the rhubarb, the acanthopanax, the radix astragali, the hawthorn and the liquorice to ensure the granularity reaches 140-200 mu; and C. weighing up the rhubarb, the acanthopanax, the radix astragali, the hawthorn and the liquorice according to the ratio and mixing and subpackaging after uniformly mixed to obtain the fish compound traditional Chinese medicinal preparation. The method has the advantages of feasibility, convenient operation, reasonable formulation and convenient use; traditional Chinese medicines have wide sources, low price, remarkable effects and no toxic or side effects; various components mutually act; and the invention simultaneously has two properties of nutrition and medicament, not only contains nutrient substances, but also has components with antibacterial activity and other bioactivities, can improve the metabolism of cultivated fishes, promote the growth and the development, improve the immunologic function, prevent and treat diseases and the like.

The invention relates to a medicinal preparation with inhibiting effect on tumor metastasis, which contains steroidal saponin extractives. The effective active components of the medicinal preparation comprise the following eight steroidal saponin general extractives which are eight steroid saponins: steroidal saponin I, steroidal saponin II, dioscin, gracillin, steroidal saponin H, steroidal saponin VII, saponin A (pennogenin-3-O-alpha-L-isodulcitol-yl(1-4)-[alpha-L-isodulcitol-yl(1-2)]-alpha-L-isodulcitol-yl(1-2)-beta-D-heteroside) and saponin B (pennogenin-3-O-alpha-L-isodulcitol-yl(1-4)-[alpha-L-isodulcitol-yl(1-2)]-alpha-L-isodulcitol-yl(1-3)-beta-D-heteroside), and the effective active components of the medicinal preparation also comprise medical dressings. The weight content of the eight steroidal saponin general extractives is 5%-30%, and the weight content of the medical dressings is 70%-95%. The invention is a medicinal preparation with less toxic and side effects and inhibiting effect on tumor metastasis.

The invention provides a traditional Chinese medicine composition for treating lumbar muscle strain. A medicine for oral administration of the traditional Chinese medicine composition is prepared from the following raw materials: 10-20 parts of herba epimedii, 10-20 parts of polygonum cuspidatum, 10-20 parts of radix achyranthis bidentatae, 10-20 parts of loranthus parasiticus, 10-20 parts of ligusticum wallichii, 10-20 parts of rhizoma corydalis, 10-20 parts of fructus liquidambaris, 10-20 parts of gentiana macrophylla, 10-20 parts of dogwood, 10-20 parts of salvia miltiorrhiza, 10-20 parts of lycopodium clavatum, 10-20 parts of ramulus mori, 10-20 parts of radix dipsaci, 10-20 parts of phryma leptostachya, 10-20 parts of fructus psoraleae, 10-20 parts of davallia mariesii, 10-20 parts of kadsura pepper stem and 10-20 parts of red paeony root; an external-use medicine of the traditional Chinese medicine composition is prepared from the following raw materials: 10-20 parts of artemisia anomala, 10-20 parts of caulis spatholobi, 10-20 parts of radix clematidis, 10-20 parts of asarum, 10-20 parts of prepared frankincense, 10-20 parts of myrrh, 10-20 parts of radix dipsaci, 10-20 parts of saposhnidoviae radix, 10-20 parts of cassia twig, 10-20 parts of davallia mariesii, 10-20 parts of fructus liquidambaris, 10-20 parts of phryma leptostachya,10-20 parts of ground beetle and 10-20 parts of kadsura pepper stem. As a treatment method of invigorating the kidney and replenishing essence, activating blood and removing stasis and activating meridians and stopping pains is clinically utilized, the traditional Chinese medicine composition achieves good clinical curative effects on treatment of lumbar muscle strain.

The invention relates to the technique of natural edible pigment in the food additives, which in detail a method for producing natural chestnut shell brown pigment, breaking the chestnut shell, extracting with base solvent after removing the flocculus, filtering the extracting fluid, condensing the filtering fluid, depositing, separating, drying and getting the natural chestnut brown pigment. The invention is characterized by the high productivity, good product quality, strong stability, simple process, low cost, changing the disposal to useful things, which opens a new way of producing natural brown pigment for food industry and at the same the industrialized production of the pigment contributes a lot for protecting ecological environment and increasing social benefit.

The invention discloses a Chinese medicinal preparation for treating psoriasis and eczema. The Chinese medicinal preparation is prepared by processing a No.1 medicament and a No.2 medicament, wherein the No.1 medicament consists of virgate wormwood herb, Indian buead, skunk bugbane, baicalin, anemarrhena asphodeloides bunge, swordlike atractylodes rhizome, largehead atractylodes rhizome, oriental waterplantain rhizome, polyporus umbellatus, kudzu-vine root, lightyellow sophora root, root of red-rooted salvia, beautiful sweetgum fruit, garter snake, densefruit pittany root-bark, white paeony root, Chinese angelica and liquoric root; and the No.2 medicament consists of officinal magnolia bark, tuber fleeceflower root, Manchurian wildginger, prepared common monkshood mother root, prepared kusnezoff monkshood root, fineleaf schizonepeta herb, divaricate saposhnikovia root, szechuan lovage rhizome, incised notopterygium rhizome root, dendrobium, ephedra herb, scorpion, dahurian angelica root and radix glycyrrhizae preparata. The No.1 medicament and the No.2 medicament are dried or baked respectively, and are prepared into fine powder for encapsulation to prepare the Chinese medicinal preparation for treating psoriasis, namely a No.1 capsule and a No.2 capsule. The Chinese medicinal preparation has the advantages of convenient preparation, convenient carrying, convenient administration, low cost, no toxic or side effect and the like, and has excellent curative effect of treating psoriasis, eczema and the like.

A vegetable oil based anisomeric cyanate radical polyurethane acrylic ester and a preparation method thereof belong to the field of photosensitive high polymer material. The adoption of isocyanate for preparing polyurethane acrylic ester results in great toxic and side effects and other problems. The structure of the vegetable oil based anisomeric cyanate radical polyurethane acrylic ester provided by the invention is shown as the general formula I. The invention uses no vulcabond with irritation and toxic and side effects, and the synthesized vegetable oil based anisomeric cyanate radical polyurethane acrylic ester can be used as photosensitive resin in the field of photosensitive high polymer material. In the formula, R1''', R2''' and R3''' are independently selected from C1-C18 alkane.

The present invention discloses an amorphous hydrocolloid dressing containing liposome, and a preparation method thereof. The amorphous hydrocolloid dressing comprises the following raw materials by mass: 10-40% of a liposome solution, 2-10% of polyethylene glycol (PEG) having a molecular weight of more than 1000, 10-35% of propylene glycol, 0.1-2% of polyvinyl alcohol (PVA), 10-35% of glycerol, 15-50% of a high water-absorbing substance, 0.1-2% of an antibacterial agent, 0.1-2% of an antioxidant, and 0.1-2% of an anti-inflammatory and anti-seepage material. According to the present invention, the three-step operation comprising liposome solution modification and hydrocolloid matrix preparation, hydrocolloid water-absorbing base particle dispersion and hydrocolloid dressing forming is performed to prepare the amorphous hydrocolloid dressing; and the amorphous hydrocolloid dressing has characteristics of good effect, rapid effect, no toxic-side effect, active anti-seepage effect, active antibacterial function, and healing promoting.

The invention discloses a preparation method of a chitosan composite preservative film. The preparation method comprises the following steps: dissolving chitosan in an acetic acid solution, heating to 50 to 65DEG C, and stirring until the chitosan is completely dissolved, so as to obtain a solution A; dispersing modified nano carbon crystal in the solution A, wherein the adding amount of the modified nano carbon crystal is 1 to 9 percent; then adding a plasticizer which accounts for 0.2 to 1 percent of the volume of the solution A, and carrying out stirring, ultrasonic dispersion, standing and ultrasonic degassing for 10 to 15 minutes to obtain a solution B; casting the solution B to form a film, standing and drying at the drying temperature of 35 to 55DEG C; then putting into 0.01 to 0.02mol/L of NaOH solution, soaking for 0.5 to 1 hour, flushing with distilled water, uncovering the film and drying in the sun to obtain the composite preservative film. The chitosan composite preservative film disclosed by the invention has relatively low water vapor permeability, so that excessive loss of water in fruits and vegetables is avoided; the chitosan composite preservative film has relatively good sterilizing function and strong antibacterial durability, i.e., an obvious sterilizing effect can be realized within one hour, and the antibacterial rates for escherichia coli and staphylococcus aureus after 48 hours still can reach 90 percent or above, so the preservation time of the fruits and the vegetables is prolonged.

The invention discloses a Chinese chestnut flower mosquito killing air freshener, which contains Chinese chestnut flower extracting solution, alcohol and distilled water. The method comprises the steps of: A) evenly mixing Chinese chestnut flower with distilled water into a distilling kettle with a weight ratio of 1: 2-8, B) starting an electric boiler, slowly opening a control valve after the pressure in boiler reaches to 0.05MPa so as to guide the steam into the distilling kettle, heating the steam in the distilling kettle, regulating a steam valve after the temperature of the kettle reaches to 90 to 100 DEG C, keeping the steam pressure in the distilling kettle between 0.01 and 0.07 MPa, opening a cooling water valve of a condensation collector, collecting the condensed solution so as to obtain the rough product of Chinese chestnut flower, C) solving 0.01 to 0.05 % of preservative in 40 to 60 % of absolute ethyl alcohol, adding 5 to 20 % of the rough product of Chinese chestnut flower obtained from step B), 0.2 to 0.7 % of menthol crystal, and water to obtain the Chinese chestnut flower mosquito killing air freshener. The Chinese chestnut flower mosquito killing air freshener of the invention is prepared from the extracting solution of the natural Chinese chestnut flower, the cost is low, the mosquito killing effect is excellent, the smell is fresh, the freshener is harmless to human body and the preparation process is simple, mild and environment-friendly.

The invention discloses a preserving stationary liquid for pathological tissues, and belongs to the technical field of sample processing. The preserving stationary liquid for pathological tissues is prepared from 12 to 15g of menthol, 10 to 20g of glycerin, 5 to 10ml of ethoxylation acetylenediol, 10 to 20g of chlorogenic acid, 30 to 70g of polyvinylpyrrolidone, 30 to 40g of sodium chloride, and 1000ml of pure water. The preserving stationary liquid for pathological tissues has the advantages that the formaldehyde solution is completely replaced; the property is stable, any toxic or side effect is avoided, the softness and hardness are proper after the pathological sample is subject to stationary treatment, the obvious shrinkage and hardening are avoided, the toughness is good, and the obvious deformation and discoloring are avoided; in the stationary process, the stationary liquid has no turbid or settling phenomenon.

The invention belongs to the field of traditional Chinese medicines and discloses a traditional Chinese medicine composition for treating constipation and a preparation method and a clinical preparation thereof. The traditional Chinese medicine composition is prepared by prepared rhubarb, linum, white paeony root, fructus aurantii, mangnolia officinalis, costusroot, semen cassiae, unprepared fleece-flower root and licorice roots northwest origin, and the traditional Chinese medicine composition has effects of clearing heat, lubricating intestines, regulating vital energy and clearing hollow viscera. According to modern pharmacology study and clinical tests, the traditional Chinese medicine composition has the advantages that the function of relaxing bowels is effectively achieved, the usage is convenient, the curative effect is remarkable, the traditional Chinese medicine composition is comfortable and safe and free of toxic and side effects, besides, the traditional Chinese medicine composition serving as a good remedy for treating the constipation can be widely applied to clinical treatment for constipation patients with functional constipation and senile constipation and other constipation patients which are required to take cathartics for ages, and particularly applicable to treatment for dryness-heat and body fluid deficiency type constipation and excessive heat and vital energy stagnation type constipation. Simultaneously, medicinal materials of the traditional Chinese medicine composition has the advantages of being free of toxics, small in medicine dependence by long-term usage, low in price, applicable to short-term and long-term usage, and having a broad market prospect.

The invention discloses a process for preparing a biological organic special composite fertilizer. The process mainly comprises the following steps: performing rough crushing on raw materials, fermenting the raw materials, performing fine crushing on the raw materials, pelletizing, performing cooling drying, and performing casual inspection on a finished product. With respect to raw material proportioning, organic fertilizers and inorganic fertilizers are combined together, so that advantages of the organic fertilizers and the inorganic fertilizers are integrated, the fertilizer has the characteristics that slow action and quick effects can be supplemented, balanced and stabilized with the combination of the organic fertilizers and the inorganic fertilizers, the fertilizer has the function of being slow, stable and long-lasting, and the purposes of balanced and efficient fertilizer supply is achieved; as the water contents of composite fertilizer granules are precisely controlled in the preparation process, the composite fertilizer granules can be relatively tightly adhered to one another, are not loosened easily in later periods, can be slowly released after being applied to soil and can stably supply fertilizers to crops for a long time, and in addition, the fertilizer is convenient to use; when being used as a base fertilizer, the fertilizer only needs to be applied once to a complete plough layer by using a fertilizer distributor, so that the working intensity is alleviated, and the labor use cost is reduced.

The invention belongs to the technical field of poultry feeding and particularly discloses a fattening feed for meat geese and a preparation method thereof. The fattening feed for the meat geese is prepared from a green feed, a concentrated feed and a feed additive in parts by mass through mixing and granulating, and drying, wherein the green feed is mainly prepared from lolium multiflorum, medicago sativa, symphytum officinale and endive and the like in parts by weight; and the feed additive is mainly prepared from prepared rehmannia roots, rice sprouts, green tangerine peels, cardamun seeds, malts, fructus forsythiae, bighead atractylodes rhizomes and the like in parts by weight through low-temperature crushing and sieving. The preparation method provided by the invention is simple and easy to implement; the fattening feed for the meat geese, prepared by the method, has the characteristics of environment protection and safety, rapid fattening speed and high slaughtering rate; and the economic benefits of feeding the meat geese can be effectively improved.

The invention discloses a functional liquid fertilizer for an orchard in a salt-alkaline land and a preparation method thereof. The functional liquid fertilizer for the orchard in the salt-alkaline land is prepared from nutritional matters and biological active matters, wherein the nutritional matters comprise nitrogen, phosphor, potassium, boron and zinc; the biological active matters comprise glutamic acid, methionine, phenylalanine, levulinic acid, genistein and chitosan oligosaccharide. The functional liquid fertilizer has the advantages that the biochemical theory of fruit growth and development is used as the instruction concept; on the basis of mineral nutrients required by the fruit development, a biological stimulation factor for promoting forming of anthocyanin, a primer elicitorfor synthesizing of the anthocyanin and the like are added, so that the synthesizing of anthocyanin is obviously promoted, the fruit flavor is improved, the red fruit rate is obviously increased, andthe safety and high-efficiency in application are realized; the convenience in use is realized, the working period is shortened, the easiness in phytotoxicity is avoided, any toxic and side effect tohuman bodies and environments is avoided, and the like.

The invention provides a potassium-bismuth titanate piezoelectric ceramic/native copper composite material and a preparation method thereof, relates to a composite material and a preparation method thereof, and aims at solving the problems of poor osteoconduction, single function and high price of the existing bone repair material. The composite material is prepared from potassium-bismuth titanate piezoelectric ceramic powder and native copper powder. The preparation method of the composite material comprises the steps of 1, preparing the potassium-bismuth titanate piezoelectric ceramic powder by a citrate hydrothermal method and then obtaining the potassium-bismuth titanate piezoelectric ceramic powder having the grain sizes ranging from 50nm to 200nm, 2, forging the native copper by a vinegar quenching method to obtain the native copper powder having the grain sizes ranging from 100 microns to 500 microns, and 3, preparing the potassium-bismuth titanate piezoelectric ceramic/native copper composite material through hot pressed sintering. The potassium-bismuth titanate piezoelectric ceramic/native copper composite material is applied to the bone repair field.