Biological collagen oral liquor and preparing method

A collagen oral liquid and collagen technology, applied in the field of oral liquid, can solve problems such as difficult absorption, poor biological activity of collagen, poor compatibility of biological activity, etc., and achieve enhanced immunity, good therapeutic effect, and moderate viscosity Effect

Inactive Publication Date: 2006-08-09
唐宝辉
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the collagen content in the existing collagen capsules is relatively low, and ordinary pigskin is generally used as a raw material. The biological activity of the prepared collagen is relatively poor, and the compatibility with the human body does not meet the requirements, and it is not easy to be absorbed by the human body. , so the health care and beauty effects that the capsule can volatilize are very limited
The application number is 93103742.5, and the name is "Water-Soluble Collagen (Gulit) Oral Medicine", which discloses a kind of oral liquid prepared from active collagen, honey and water prepared from freshly slaughtered calfskin. The liquid is used for setting bones and treating osteoporosis, but because the active ingredient in the oral liquid is only one kind of collagen, and the content of collagen is low, only 10% of the total weight, so the various substances contained in the oral liquid Nutrients are difficult to meet the intake required by the injured human body or animals, and can not play a good bone setting and treatment of osteoporosis, and the selected collagen is prepared from bovine bone and ordinary bovine hide. Its biological activity and compatibility with the human body are still poor, and the oral liquid is sterilized for a long time in an environment of 85-100°C to achieve the sterilization effect, which greatly reduces the activity of collagen, thus further reducing the The therapeutic effect of the oral liquid

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] 1) Preparation of biological collagen:

[0019] a. Choose healthy, virus-free, fragrant pigs less than 3 months old, clean, slaughter and peel them;

[0020] b. Remove hair and fat layer to obtain hairless and fat-free pigskin;

[0021] c, the pigskin is disinfected and sterilized;

[0022] d. Clean the pigskin after disinfection and sterilization with water;

[0023] e. Cook the pigskin with physiological saline until it becomes jelly, the cooking temperature is 30°C; the pressure is 0.2Mpa, and the cooking time is 2 hours;

[0024] f. The resulting protein collagen with a molecular weight of 50,000 to 80,000 is subjected to high-temperature acidic degradation, that is, under the condition of a pH value of 4, the collagen is instantly heated to 180°C and kept for 10 seconds, and then cooled for 10 seconds to 15°C; and the collagen content and amino acid content are not damaged, the protein content is kept at 95-99%, and the amino acid content is kept at 85-95%;

[...

Embodiment 2

[0029] 1) Preparation of biological collagen:

[0030] a. Choose healthy, virus-free, fragrant pigs less than 3 months old, clean, slaughter and peel them;

[0031] b. Remove hair and fat layer to obtain hairless and fat-free pigskin;

[0032] c, the pigskin is disinfected and sterilized;

[0033] d. Clean the pigskin after disinfection and sterilization with water;

[0034] e. Cook the pigskin with physiological saline until it becomes jelly, the cooking temperature is 40°C; the pressure is 0.4Mpa, and the cooking time is 4 hours;

[0035] f. The resulting protein collagen with a molecular weight of 50,000 to 80,000 is subjected to high-temperature acidic degradation, that is, under the condition of a pH value of 6, the collagen is instantly heated to 250° C. and kept for 30 seconds, and then cooled to within 3 seconds. 25°C to reduce the molecular weight to less than 10,000; and keep the collagen content and amino acid content undamaged, the protein content is kept at 95-...

Embodiment 3

[0040] 1) Preparation of biological collagen:

[0041] a. Choose healthy, virus-free, fragrant pigs less than 3 months old, clean, slaughter and peel them;

[0042] b. Remove hair and fat layer to obtain hairless and fat-free pigskin;

[0043] c, the pigskin is disinfected and sterilized;

[0044] d. Clean the pigskin after disinfection and sterilization with water;

[0045] e. Cook the pigskin with physiological saline until it becomes jelly, the cooking temperature is 35°C; the pressure is 0.3Mpa, and the cooking time is 3 hours;

[0046]f. The resulting protein collagen with a molecular weight of 50,000 to 80,000 is subjected to high-temperature acidic degradation, that is, under the condition of a pH value of 5, the collagen is instantly heated to 200°C and kept for 15 seconds, and then cooled for 15 seconds to 20°C, without damaging the collagen content and amino acid content, the protein content is kept at 95-99%, and the amino acid content is kept at 85-95%;

[0047...

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PUM

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Abstract

The invention relates to biology collagen oral liquid and the manufacture method that includes the following steps: making biology collagen: adopting healthy three month age pig, cleaning, slaying, peeling, depluming, degreasing, sterilizing, cleaning the skin, boiling the pig skin in biology brine, until freezing into gel state to gain collagen that has molecular weight at 50-80 thousand to take high temperature acid degradation, pH value is 4-6, heating the collagen fast to 180-250 degree centigrade and cooling to 15-25 degree centigrade to decrease the molecular weight under 10 thousand, filtering and purifying, removing grease, to gain collagen; making biology collagen oral liquid: adopting thickness at 5-15% collagen liquid 100 portions, calcium salt 1.5-5 portions to mix to equal, filtering the mixture, sterilization, to gain biology collagen oral liquid. It has good effect to cure bone broken and also has function of beauty treatment, and enhancing immunity.

Description

(1) Technical field: [0001] The invention relates to an oral liquid, in particular to a bio-collagen oral liquid made from pigskin; the invention also relates to a preparation method of the bio-collagen oral liquid. (two) background technology: [0002] Collagen is a polymer that makes up various extracellular matrix. It plays the role of binding tissue in animal cells. It is the most important component of extracellular matrix and the most important structural protein of animal connective tissue. It is mainly insoluble Fibrin exists in the form of fibrin, which accounts for about 33% of protein in the composition of the human body, and can protect and connect various tissues to support the structure of the human body. Collagen is the main component of human tissue. It has an inseparable relationship with various organs, tissues and cells of the human body. It is suitable for the repair and regeneration of human organ tissues. For example, it can help the healing of human wo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/39A61P19/08
Inventor 唐宝辉
Owner 唐宝辉
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