37 results about "Mouse Auricle" patented technology

The invention discloses an external medicament for treating bacterial vaginosis and colpitis mycotica. The external medicament is a medicament prepared from Chinese medicinal raw materials including 35-70 parts by weight of amur corktree bark, 30-60 parts by weight of lightyellow sophora root, 30-60 parts by weight of cortex ailanthi, 20-40 parts by weight of polygonum aviculare, 10-35 parts by weight of selinum japenious seed and 1-2.5 parts by weight of borneol according to the conventional preparation method. As proved by a pharmacodynamic test, the medicament has a remarkable in-vitro antibacterial action, and can be used for effectively killing and suppressing common pathogenic bacteria of reproductive tract infection; the medicament has a remarkable treatment effect on rabbit colpitis mycotica; compared with a model control group, a medicament group has the advantages: the vagina cleanliness and curative ratio are increased remarkably, and the pathological feature of rabbit colpitis mycotica can be improved remarkably; the medicament has a remarkable anti-inflammatory effect, and can be used for remarkably relieving dimethyl benzene-caused mouse auricle inflammation, suppressing the formation of mouse granuloma and reducing the mouse abdominal cavity capillary permeability; and the medicament has a certain itching relieving effect.

The invention discloses new dihydroiso-coumarin glucoside compounds shown in a formula I, which are extracted and separated from Periplaneta americanna medicinal materials. Through mouse auricle swelling tests, rat granulation tissue hyperblastosis tests and the like, results show that the compounds have effects of resisting inflammation, promoting wounds to heal and the like; and the compounds can be used for preparing medicines for treating inflammation, ulcers, wounds, incised wounds, fistula, burn, scalding and the like, particularly medicines for preventing and treating diseases related to inflammation resistance, promotion of granulation tissue hyperblastosis, wound healing and the like, and have high clinical application value. The invention provides a preparation method for the compounds shown in the formula I.

The invention is a functional skin care product containing purslane extractive. Raw materials of the functional skin care product include, by weight, 10 parts of purslane extractive, 1-2 parts of Prinsepia utilis rogle oil, 2-5 parts of glycerol, 0.3-0.5 parts of crylic acid (ester) / C10-30 alkanol acrylate cross-linked polymer, 2-3 parts of 1,2-pentanediol, 1-5 parts of synthesized squalane, 1-2 parts of tocopheryl acetate, 2-3 parts of cetostearyl alcohol, 0.1-0.2 part of allantoin, 0.3-0.8 part of sodium hyaluronate, 3-5 parts of Butyrospermum parkii butter, and 100 parts of deionized water. Or the Prinsepia utilis rogle oil and the Butyrospermum parkii butter are not added. By the aid of animal experiments, namely, mouse auricle swelling models due to dimethlbenzene, the functional skin care product containing purslane extractive is fine in anti-inflammation and anti-allergy effects, mild in nature and fine in safety, and is free of toxic reaction and anaphylaxis. The functional skin care product has an adjuvant therapy function to skin barrier recovery of common discosmetic dermatosis such as hormone dependent dermatitis and acne, and is fine in curative effect and safety.

The invention belongs to the technical field of traditional Chinese medicine compound, and in particular relates to an anti-inflammatory traditional Chinese medicine compound and its preparation method and application. The composition of the compound comprises the following raw materials in parts by weight: 5-15 parts of golden fruit olive, 20-45 parts of red plum, and 10 parts of arhat tea ‑25 parts, 10‑25 parts of Siberian Crane, and 6‑18 parts of Scutellaria baicalensis, 10‑25 parts of forsythia, 10‑25 parts of Nanlangen, 10‑25 parts of mountain silver flower Compound. The anti-inflammatory traditional Chinese medicine compound provided by the present invention can significantly inhibit the degree of mouse auricle swelling caused by xylene, and significantly reduce the levels of NO, IL-6 and TNF-α produced by LPS-stimulated RAW264.7 cells. Experiments have shown that the anti-inflammatory Chinese medicine compound provided by the invention has significant anti-inflammatory and anti-inflammatory effects, has definite curative effect, high safety, and easy-to-get raw materials. When it is prepared into a pharmaceutical preparation, a pharmaceutically acceptable carrier can be added. Conventional techniques of pharmacy prepare different dosage forms, which can be used to prepare drugs with anti-inflammatory effects.

The invention discloses a method for chemically synthesizing a mangiferin hexa-butyl-esterified derivative and a pharmacological effect of resisting inflammation and reducing blood sugar of the derivative. The chemical structural formula of the derivative is shown in the specifications. The derivative has a remarkable effect of inhibiting mouse auricle tumefaction caused by dimethylbenzene; and the derivative has a remarkable effect of treating diabetic mice induced by alloxan.

The invention discloses a method for chemically synthesizing a mangiferin hepta-propyl-esterified derivative and a pharmacological effect of resisting inflammation and reducing blood sugar of the derivative. The chemical structural formula of the derivative is shown in the specifications. The derivative has a remarkable effect of inhibiting mouse auricle tumefaction caused by dimethylbenzene; and the derivative has a remarkable effect of treating diabetic mice induced by alloxan.

The invention provides a rhizoma imperatae water-stage extract which is prepared by the following steps of: 1) performing backflow extraction of the coarse powder of rhizoma imperatae by use of 50-90% ethanol water by weight, and concentrating the extracting solution to obtain extract; and 2) adding water into the extract obtained in the step 1) and mixing to obtain suspension, extracting with petroleum ether, ethyl acetate and n-butyl alcohol sequentially, evaporating the obtained raffinate, and drying to obtain the rhizoma imperatae water-stage extract. In the invention, the effective anti-inflammation part in the rhizoma imperatae is screened through stage extraction to obtain the rhizoma imperatae water-stage extract. Among all stage extracts of rhizoma imperatae, the extract has the most obvious effect on inhibiting the mouse auricle swelling inflammation caused by paraxylene, and is expected to be used as an anti-inflammation medicine for preventing inflammation.