50 results about "Blood filtering" patented technology

Clot material may be removed from a patient and separated from blood so that the blood may be collected using an efficient dual-stroke technique. The methods described herein withdraw clot and blood from a patient during a first stoke of a pump at a first rate, filter the blood to remove clot, and drive the filtered blood into a collection chamber at a second rate that is different from the first rate. The first rate may be optimized to disrupt and remove clot, while the second rate may be optimized to move the blood without damaging, e.g., lysing, the blood.

Disclosed herein are devices, systems, and methods for at least partially automatically aspirating clot material and blood from the vasculature of a patient, filtering the blood from the clot material, and returning the blood to the vasculature of the patient. In some embodiments, a system in accordance with the present technology can include (i) an aspiration catheter configured to be positioned within the vasculature of a patient proximate to clot material therein, (ii) an aspiration assembly selectively fluidly couplable to the aspiration catheter, (iii) a filter assembly selectively fluidly couplable to the aspiration assembly, (iv) a reinfusion and flushing assembly selectively fluidly couplable to the filter assembly, (v) a reinfusion catheter selectively fluidly couplable to the reinfusion and flushing assembly and configured to be positioned within the vasculature, and (vi) a control system communicatively coupled to the aspiration assembly, the filter assembly, and / or the reinfusion and flushing assembly.

The utility model discloses a blood collection card, and belongs to the technical field of body fluid collection cards. Comprising a supporting clamping shell, a PVC bottom plate, a serum collecting pad, a buffering pad, a blood filtering pad and a cell blocking pad, and a mold strip is packaged in the supporting clamping shell; a collection window is arranged on the top surface of one end of the supporting clamping shell; a breaking weak part is arranged at the middle rear part of the supporting clamping shell; the die strip comprises the serum collecting pad which is adhered to the top surface of the PVC bottom plate; one end of the buffer pad is lapped to the top surface of one end of the serum collection pad; the other end of the buffer pad is adhered to the top surface of the PVC bottom plate; one end of the blood filtering pad is lapped to the top surface of one end of the buffer pad; the other end of the blood filtering pad is adhered to the top surface of the PVC bottom plate; one end of the cell blocking pad is lapped to the top surface of one end of the blood filtering pad; the other end of the cell barrier pad is adhered to the top surface of the PVC bottom plate; the blood collection card disclosed by the utility model can be used for separating serum from blood cells, and is suitable for in-vitro detection of serum markers.

The reagent card comprises a shell and a test strip, a sample adding groove and a test window are formed in the shell at intervals, the sample adding groove sequentially comprises an upper cover, a uniform mixing bin and a blood filtering film from top to bottom, a sample adding hole is formed in the middle of the uniform mixing bin, and the test strip is arranged in the sample adding hole. The upper cover covers the upper end face of the uniform mixing bin in an openable and closable manner to shield the sample adding hole, a first film is arranged on the bottom surface of the sample adding hole, a second film is arranged on the bottom surface of the uniform mixing bin, the second film is positioned below the first film, and a sample diluent is filled between the second film and the first film, the blood filtering film is arranged below the second film, and a sampling needle is arranged on the bottom surface of the upper cover. And a pressing part which can be pressed to deform is arranged on the upper cover corresponding to the sampling needle. Due to the design of the sample adding groove, the applicability of a scene is improved, and a sample dilution step is omitted. The advantages of the four detection indexes complement each other, the operation is simple and rapid, the cost is low, the result is accurate, the sensitivity is high, the specificity is high, and the accuracy of vascular inflammation detection can be effectively improved.

Vascular filters and deflectors and methods for filtering bodily fluids. A blood filtering assembly can capture embolic material dislodged or generated during an endovascular procedure to inhibit or prevent the material from entering the cerebral vasculature. A blood deflecting assembly can deflect embolic material dislodged or generated during an endovascular procedure to inhibit or prevent the material from entering the cerebral vasculature.

An extracorporeal blood filtering machine can include a blood circuit, an effluent circuit, and a source fluid circuit and can be controlled by a controller. The extracorporeal blood filtering machine can also include access ports for connecting the source fluid circuit to the blood circuit, as well as blood sensors to detect possible issues with the extracorporeal blood filtering machine. The extracorporeal blood filtering machine can include density sensors and flow sensors that enable it to be more accurate and to operate while being transported. The extracorporeal blood filtering machine can further include a user interface and can display fluid inflow / outflow information. A medical fluid container can automatically empty after being filled. An apparatus for supporting a medical fluid container can include a hanger and an attachment member with the apparatus able to adjust to ensure the medical fluid container remains properly oriented directly under a medical fluid container scale.

The application relates to the technical field of kidney dialysis medical equipment, in particular to a kidney dialysis blood multi-stage filtering device with optimized flow channels, which comprises a device body; three groups of filtering cylinders are driven in linkage by a micro motor, a rotating shaft, a driving gear and a transmission gear ring, the driving gear and the transmission gear ring are sequentially reduced from top to bottom, the three groups of filtering cylinders rotate at different rotating speeds, the internal filtering units are driven to work efficiently, the filtering unit apertures are sequentially reduced from top to bottom, the filtering unit apertures are respectively set as pretreatment filtering units, precision filtering units and deep adsorption filtering units, a grading purification system is formed, different molecular weight toxins can be targetedly removed, the linkage structure of a pawl, a ratchet ring, a connecting rotating rod and a return spring can dynamically adjust the angle of the filtering units according to the changes of blood flow and pollution degree, the occurrence risk of low proteinemia of patients can be effectively reduced, the device can be flexibly adapted to the disease differences of different patients, individualized precise treatment can be realized, and the kidney dialysis treatment effect is improved.

Disclosed herein are clot treatment systems with filtering syringes, and associated devices and methods. The filtering syringe can be coupled to a catheter subsystem insertable within a patient. The filtering syringe can aspirate material (e.g., clot material, blood, etc.) from a patient via the catheter subsystem. The filtering syringe can include a plunger assembly, and the plunger assembly can include one or more filters. Each of the filters can be configured to (i) allow at least a first portion of aspirated material (e.g., blood) to pass through at least one of the filters, and (ii) prevent at least a second portion of the aspirated material (e.g., clot material) from passing through at least one of the filters. In some embodiments, the filtering syringe is fluidly coupled to a filtered material subsystem that can fluidly couple the filtering syringe to the patient or another suitable fluid outflow location.

A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.

Disclosed herein are devices, systems, and methods for at least partially automatically aspirating clot material and blood from the vasculature of a patient, filtering the blood from the clot material, and returning the blood to the vasculature of the patient. In some embodiments, a system in accordance with the present technology can include (i) an aspiration catheter configured to be positioned within the vasculature of a patient proximate to clot material therein, (ii) an aspiration assembly selectively fluidly couplable to the aspiration catheter, (iii) a filter assembly selectively fluidly couplable to the aspiration assembly, (iv) a reinfusion and flushing assembly selectively fluidly couplable to the filter assembly, (v) a reinfusion catheter selectively fluidly couplable to the reinfusion and flushing assembly and configured to be positioned within the vasculature, and (vi) a control system communicatively coupled to the aspiration assembly, the filter assembly, and / or the reinfusion and flushing assembly.

An extracorporeal blood filtering machine can include a blood circuit, an effluent circuit, and a source fluid circuit and can be controlled by a controller. The extracorporeal blood filtering machine can also include access ports for connecting the source fluid circuit to the blood circuit, as well as blood sensors to detect possible issues with the extracorporeal blood filtering machine. The extracorporeal blood filtering machine can include density sensors and flow sensors that enable it to be more accurate and to operate while being transported. The extracorporeal blood filtering machine can further include a user interface and can display fluid inflow / outflow information. A medical fluid container can automatically empty after being filled. An apparatus for supporting a medical fluid container can include a hanger and an attachment member with the apparatus able to adjust to ensure the medical fluid container remains properly oriented directly under a medical fluid container scale.

The plasma separating device comprises a blood collecting cylinder, a plasma collecting box and a collecting needle assembly, a pre-filtering film and a blood filtering film are sequentially fixed in an opening in the lower end of the blood collecting cylinder from top to bottom, and the plasma collecting box is made of elastic materials. The plasma collecting box can be detachably connected with the blood collecting cylinder and the collecting needle assembly. A water absorbing block is arranged in the plasma collecting box, and when the plasma collecting box is connected with the blood collecting cylinder, the upper surface of the water absorbing block is in direct contact with the blood filtering film. By utilizing the physical form difference between blood visible components and plasma components, the blood collecting cylinder is connected with the plasma collecting box, the upper surface of the water absorbing block is in direct contact with the blood filtering film, and the water absorbing block provides strong capillary force, so that the plasma filtering efficiency is improved; then the plasma collecting box is fixedly connected with the collecting needle assembly, plasma can be separated from the water absorbing block and flows out of the collecting needle assembly by extruding the plasma collecting box through external force, and operation is convenient and fast.

The utility model discloses a medical electrochemical detection test strip with an anti-interference effect. The medical electrochemical detection test strip sequentially comprises a substrate, a four-electrode system, a sensitive layer, an immunoadsorption layer, a first blood filtering layer and a hydrophilic layer from bottom to top, the hydrophilic layer is prepared by carrying out Plasma hydrophilic treatment on PET (Polyethylene Terephthalate); the first blood filtering layer is made of a glass fiber material; the immunoadsorption layer comprises an anti-interference pad, the anti-interference pad is made of polyester fibers, and the anti-interference pad contains an anti-interference test; the sensitive layer comprises a cellulose acetate fiber pad membrane of which the outer surface is loaded with an antibody; the four-electrode system is composed of a working electrode, a reference electrode, a counter electrode and a contrast electrode, and the four-electrode system is formed by printing carbon paste or silver paste on the substrate. According to the electrochemical detection test strip with the structure, the anti-interference performance can be effectively improved, and the detection accuracy and precision are greatly improved.

The invention relates to the fields of therapy and drug delivery. It is based on an unexpected finding that a combination of an oligonucleotide-based medicament with a saponin component comprising a penta-cyclic triterpene saponin of a 12,13-dehydrooleanane aglycone core, not only does not appear to be associated with oligonucleotide medicament-induced nephrotoxic effects after systemic administration in vivo, but also that it allows the oligonucleotide-based medicament to enter and act on its nucleic acid target inside of the kidney cells instead of remaining unproductively trapped in renal subcellular compartments or being eliminated into the urine via the renal glomerular filtration system. In line with this finding, herein disclosed are therapeutic combinations, compositions, and formulations, as well as methods of treatment involving their administration, which comprise an oligonucleotide-based medicament that acts on an intracellular nucleic acid target in the kidney cells and / or in the cells of the spleen, being the other blood filtering organ in addition to the kidney, and a saponin component that enables the effective release of said medicament inside of these cells, thus allowing its use at a much lower and safer dose. The provision of the presented herein therapeutic combinations enables effective modulation of gene expression in the kidney and / or spleen cells and, therefore, it opens not only new treatment options for kidney diseases, in particular those involving inflammation and / or splenomegaly, but also for diseases of other organs which affect or are affected by the pathological processes happening in the kidneys and / or in the spleen, in particular being inflammatory processes.

The utility model relates to the technical field of in-vitro diagnosis and medical application, and discloses a lateral immunochromatography quantitative reagent which comprises a bottom plate, a sample pad is fixedly connected to the rightmost side of the upper portion of the bottom plate, a blood filtering pad is arranged on the left portion of the sample pad, a combining pad is arranged on the left portion of the blood filtering pad, and the combining pad is arranged on the right portion of the blood filtering pad. An NC membrane is arranged at the left part of the combination pad, a water absorption pad is arranged at the left part of the NC membrane, the NC membrane is coated with a detection antigen and is used for fixing a target substance in a sample, the sample pad is used for receiving and primarily treating the sample to be detected, and the sample pad and the blood filtering pad are fixed through an adhesive. According to the utility model, when whole blood and peripheral blood are detected, the content of folic acid in the body of a person to be detected can be obtained without centrifugation and red blood cell counting, so that folic acid detection can be realized in primary hospitals and village and town clinics.

The utility model relates to the technical field of thrombus filtering, and discloses a thrombus filtering device which comprises an equipment liquid inlet pipeline, an equipment liquid outlet pipeline and a thrombus filtering pipeline, a valve is further arranged at the liquid inlet of the equipment liquid inlet pipeline; the filtering assembly is used for filtering blood entering the thrombus filtering device; the equipment liquid outlet pipeline is used for conveying the filtered blood back to the living body; the driving mechanism is communicated with the equipment liquid inlet pipeline; in the blood filtering process, the driving mechanism generates negative pressure in the liquid inlet pipeline of the equipment so as to drive blood to flow through the opened valve and enter the filtering assembly to filter thrombus; in the blood conveying process, the driving mechanism generates positive pressure in the equipment liquid inlet pipeline, the valve is closed, and blood enters the equipment liquid outlet pipeline from the equipment liquid inlet pipeline and returns to the living body. By means of the structure, thrombus can be filtered, filtered blood drawn out of the body is re-infused into the body of a patient, and then the problem of blood waste is avoided.

A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.

The invention discloses a trace whole-blood heart failure marker immunochromatography detection test strip and a preparation method thereof, and relates to the technical field of heart failure detection. The microscale whole blood heart failure marker immunochromatography detection test strip comprises a blood filtering pad, a combination pad, a nitrocellulose membrane, absorbent paper and a polystyrene bottom plate, the blood filtering pad, the combination pad, the nitrocellulose membrane and the absorbent paper are sequentially fixed to the polystyrene bottom plate, and a detection line T and a quality control line C are arranged on the two sides of the nitrocellulose membrane respectively. The detection line T is adjacent to the combination pad, and the quality control line C is adjacent to the absorbent paper. The invention also provides a preparation method and a use method of the microscale whole blood heart failure marker immunochromatography detection test strip, the detection sensitivity is high, the operation is simple, and the problem of large interference of endogenous peroxidase in fingertip blood / microscale whole blood / plasma under an acidic condition in the prior art is effectively solved.

A parameter for controlling an inlet pump speed in a hemofiltration system is derived from fitting a line to multiple data points of pressure versus pump speed. The pressure is measured in a channel connecting an inlet pump to an outlet pump. First, the inlet pump operates and the pressure is sampled until it is stabilized, then the inlet pump speed is increased and pressure is measured to obtain a data point. Subsequently the inlet pump speed is decreased and pressure is measured to obtain another data point. A line is fit through the data points to obtain the parameter.

An extracorporeal blood filtering machine can include a blood circuit, an effluent circuit, and a source fluid circuit and can be controlled by a controller. The extracorporeal blood filtering machine can also include access ports for connecting the source fluid circuit to the blood circuit, as well as blood sensors to detect possible issues with the extracorporeal blood filtering machine. The extracorporeal blood filtering machine can include density sensors and flow sensors that enable it to be more accurate and to operate while being transported. The extracorporeal blood filtering machine can further include a user interface and can display fluid inflow / outflow information. A medical fluid container can automatically empty after being filled. An apparatus for supporting a medical fluid container can include a hanger and an attachment member with the apparatus able to adjust to ensure the medical fluid container remains properly oriented directly under a medical fluid container scale.

A controller for controlling an apparatus comprising a blood pump, oxygenator, and blood filtering system connected together by blood flow tubing and to a patient to circulate blood from the patient through the apparatus and back to the patient, to oxygenate and filter the blood, the controller comprising at least one communication interface operable to receive signals generated responsive to monitored parameters characterizing blood flow and / or quality of blood from the patient circulating through the apparatus and configured to: determine values for the monitored parameters based on the monitoring signals; determine whether or not a value determined for a given monitored parameter for blood circulating through the apparatus is within a normative range for the parameter; and generate an alarm to alert an operator of the system if the value is not within the normative range.

The invention belongs to the technical field of protein detection, and particularly relates to a protein detection device and a detection method. The protein detection device comprises: a liquid inlet channel for adding a sample to be detected; the main runner is communicated with the liquid inlet channel; the blood filtering membrane is used for filtering the to-be-detected sample; a plurality of sub-channels; the liquid inlet end of each sub-channel is communicated with the main runner, and the liquid outlet end is communicated with the waste liquid cavity; a first turbulent flow body array and a second turbulent flow body array are arranged in the sub-channel along a sample flowing direction; the antibody film is arranged above the sub-channel in a covering manner; wherein the lower surfaces, corresponding to the first turbulence body array and the second turbulence body array of each sub-channel, of the antibody film are respectively provided with a fluorescence labeled antibody and a capture antibody; and after the antibody film at the corresponding antibody is pressed, the antibody is attached to the corresponding turbulent flow body array. According to the protein detection device, corresponding antigens can be arranged on the antibody films above the sub-channels, and whether one or more corresponding antigens exist or not can be rapidly detected while serum is separated from whole blood on the basis of a one-time sampling principle.

1. The name of the product of this design: blood filter tank. 2. Purpose of this design product: used in blood filtration device. 3. The design key point of this appearance design product lies in the shape. 4. The picture or photo that best illustrates the design points: Stereoscopic diagram 1. 5. Other situations that require explanation Other explanations: The lower shell of the product is made of transparent material.

The utility model discloses a heat sealing device which is provided with a machine frame, a position changing module and a heat sealing module, the heat sealing module is connected to the machine frame in a sliding mode in the height direction of the machine frame, and the position changing module is connected with the heat sealing module and can drive the heat sealing module to slide. When the heat sealing work of the guide pipe on the lower side of the white filter module is carried out, the heat sealing module can be driven by the transposition module to carry out heat sealing on a plurality of point positions of the guide pipe from bottom to top, after heat sealing of all the point positions of the guide pipe is completed, the guide pipe can be disconnected through all the heat sealing points, and after the heat sealing points close to a collecting bag are disconnected, sealing of the collecting bag is formed. After other heat sealing points are broken, the catheter can be divided into a plurality of sections of sub-tubes filled with blood subjected to white blood filtering, and through automatic sectional heat sealing of the heat sealing device, manpower needed by heat sealing work can be reduced, heat sealing efficiency can be improved, and convenience is provided for heat sealing after white blood filtering.

Multi-filter endolumenal methods and systems for filtering fluids within the body. In some embodiments a multi-filter blood filtering system captures and removes particulates dislodge or generated during a surgical procedure and circulating in a patient's vasculature. In some embodiments a dual filter system protects the cerebral vasculature during a cardiac valve repair or replacement procedure.

The utility model discloses a live pig slaughtering suspension device, which relates to the technical field of livestock slaughtering and comprises a slaughtering table, a hydraulic cylinder is fixedly mounted on the slaughtering table, a supporting seat is fixedly mounted at the lifting end of the hydraulic cylinder, a hook is fixedly mounted at the bottom of the supporting seat, and a pig leg hanging mechanism for binding rear legs of a live pig is hung on the hook. A pig leg traction mechanism used for straightening front legs of live pigs is arranged on the slaughtering table, a pig blood collecting box is arranged on the slaughtering table, and a pig blood filtering mechanism used for filtering and discharging pig blood is arranged in the pig blood collecting box; according to the device, through the arrangement of the hydraulic cylinder, the pig leg tying and hanging mechanism, the pig leg traction mechanism, the pig blood collecting box, the pig blood filtering mechanism and other structures, the hydraulic cylinder can tighten the rear legs of a live pig and lift the live pig upwards, the bandage can straighten the front legs of the live pig to prevent the front legs of the live pig from kicking disorderly and injuring operators accidentally, and the filter screen can filter the collected pig blood; and the filtered pig blood is released through the release tube, so that the pig blood is convenient to collect.

The application discloses a blood sampling and detection card integrated device, relates to the technical field of blood sampling, and comprises a blood sampling needle and a detection card main body. One end of the blood sampling needle is provided with a hose, and one end of the hose is provided with a vacuum blood storage tube. A serum treatment tube is arranged at the bottom of the vacuum blood storage tube. A connecting assembly for quickly guiding blood is arranged between the vacuum blood storage tube and the serum treatment tube, and the connecting assembly comprises an inner clamping groove and an outer clamping plate. The outer clamping plate is slidably arranged in the inner clamping groove. The blood sampling and detection card integrated device can prevent blood coagulation through the anticoagulant in the built-in groove of the vacuum blood storage tube. The blood filtering film gasket treated by the anti-red blood cell antibody in the serum treatment tube can effectively filter red blood cells, obtain pure serum, avoid red blood cell interference on the detection result, and prevent blood or serum leakage and reduce the risk of cross contamination in the initial state through the close combination of the sealing gasket plate and the built-in groove and the sealing design of the aluminum foil.

The invention provides bone marrow blood collecting and filtering equipment, and belongs to the field of bone marrow blood collection, the bone marrow blood collecting and filtering equipment comprises a fixing frame component, the fixing frame component is detachably connected with a main pipeline and an injection head, the main pipeline is further detachably connected with a medicine storage bottle through an injection pipeline, the medicine storage bottle is filled with heparin liquid, and the injection head is detachably connected with the main pipeline. A fixed pressure component is installed on the injection pipeline, a collecting component is detachably installed at the end, away from the fixing frame component, of the main pipeline, and the collecting component can automatically collect spinal cord blood. The heparin liquid in the medicine storage bottle can be automatically sucked, the bone marrow blood is sucked and flows through the multi-stage filter and can be filtered to obtain relatively pure hematopoietic stem cells, so that the device can realize highly automatic collection of the bone marrow blood without repeatedly replacing an injector and a tedious artificial bone marrow blood filtering process; and the dependence on medical staff is reduced.

The present invention relates to the technical field of blood filtration materials, and in particular to MOFs modified PBT leukocyte-removing filter material and its preparation method and application. Take aminoterephthalic acid and dissolve it in N, N-dimethylformamide, then add chitosan and ultrasonically dissolve it to obtain a mixed solution; weigh zirconium tetrachloride and dissolve it in N, N-dimethylformamide to obtain a metal salt solution, add the mixed solution to the metal salt solution and mix it evenly, after the reaction, wash, dry, and obtain UiO-66-NH2@chitosan; Take UiO-66-NH2@chitosan and add it to water to prepare a finishing liquid, take PBT non-woven fabric and immerse it in the finishing liquid, take out the PBT non-woven fabric after immersion and drying, finally wash it with deionized water, and dry it to obtain the MOFs modified leukocyte-removing PBT filter material. The filter material of the present invention has both high leukocyte filtration efficiency, red blood cell and platelet recovery rate and high efficiency antibacterial function.

An extracorporeal blood filtering machine can include a blood circuit, an effluent circuit, and a source fluid circuit and can be controlled by a controller. The extracorporeal blood filtering machine can also include access ports for connecting the source fluid circuit to the blood circuit, as well as blood sensors to detect possible issues with the extracorporeal blood filtering machine. The extracorporeal blood filtering machine can include density sensors and flow sensors that enable it to be more accurate and to operate while being transported. The extracorporeal blood filtering machine can further include a user interface and can display fluid inflow / outflow information. A medical fluid container can automatically empty after being filled. An apparatus for supporting a medical fluid container can include a hanger and an attachment member with the apparatus able to adjust to ensure the medical fluid container remains properly oriented directly under a medical fluid container scale.