18 results about "Blood filtering" patented technology

Disclosed herein are devices, systems, and methods for at least partially automatically aspirating clot material and blood from the vasculature of a patient, filtering the blood from the clot material, and returning the blood to the vasculature of the patient. In some embodiments, a system in accordance with the present technology can include (i) an aspiration catheter configured to be positioned within the vasculature of a patient proximate to clot material therein, (ii) an aspiration assembly selectively fluidly couplable to the aspiration catheter, (iii) a filter assembly selectively fluidly couplable to the aspiration assembly, (iv) a reinfusion and flushing assembly selectively fluidly couplable to the filter assembly, (v) a reinfusion catheter selectively fluidly couplable to the reinfusion and flushing assembly and configured to be positioned within the vasculature, and (vi) a control system communicatively coupled to the aspiration assembly, the filter assembly, and / or the reinfusion and flushing assembly.

The application relates to the technical field of kidney dialysis medical equipment, in particular to a kidney dialysis blood multi-stage filtering device with optimized flow channels, which comprises a device body; three groups of filtering cylinders are driven in linkage by a micro motor, a rotating shaft, a driving gear and a transmission gear ring, the driving gear and the transmission gear ring are sequentially reduced from top to bottom, the three groups of filtering cylinders rotate at different rotating speeds, the internal filtering units are driven to work efficiently, the filtering unit apertures are sequentially reduced from top to bottom, the filtering unit apertures are respectively set as pretreatment filtering units, precision filtering units and deep adsorption filtering units, a grading purification system is formed, different molecular weight toxins can be targetedly removed, the linkage structure of a pawl, a ratchet ring, a connecting rotating rod and a return spring can dynamically adjust the angle of the filtering units according to the changes of blood flow and pollution degree, the occurrence risk of low proteinemia of patients can be effectively reduced, the device can be flexibly adapted to the disease differences of different patients, individualized precise treatment can be realized, and the kidney dialysis treatment effect is improved.

Disclosed herein are clot treatment systems with filtering syringes, and associated devices and methods. The filtering syringe can be coupled to a catheter subsystem insertable within a patient. The filtering syringe can aspirate material (e.g., clot material, blood, etc.) from a patient via the catheter subsystem. The filtering syringe can include a plunger assembly, and the plunger assembly can include one or more filters. Each of the filters can be configured to (i) allow at least a first portion of aspirated material (e.g., blood) to pass through at least one of the filters, and (ii) prevent at least a second portion of the aspirated material (e.g., clot material) from passing through at least one of the filters. In some embodiments, the filtering syringe is fluidly coupled to a filtered material subsystem that can fluidly couple the filtering syringe to the patient or another suitable fluid outflow location.

A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.

Disclosed herein are devices, systems, and methods for at least partially automatically aspirating clot material and blood from the vasculature of a patient, filtering the blood from the clot material, and returning the blood to the vasculature of the patient. In some embodiments, a system in accordance with the present technology can include (i) an aspiration catheter configured to be positioned within the vasculature of a patient proximate to clot material therein, (ii) an aspiration assembly selectively fluidly couplable to the aspiration catheter, (iii) a filter assembly selectively fluidly couplable to the aspiration assembly, (iv) a reinfusion and flushing assembly selectively fluidly couplable to the filter assembly, (v) a reinfusion catheter selectively fluidly couplable to the reinfusion and flushing assembly and configured to be positioned within the vasculature, and (vi) a control system communicatively coupled to the aspiration assembly, the filter assembly, and / or the reinfusion and flushing assembly.

The utility model discloses a medical electrochemical detection test strip with an anti-interference effect. The medical electrochemical detection test strip sequentially comprises a substrate, a four-electrode system, a sensitive layer, an immunoadsorption layer, a first blood filtering layer and a hydrophilic layer from bottom to top, the hydrophilic layer is prepared by carrying out Plasma hydrophilic treatment on PET (Polyethylene Terephthalate); the first blood filtering layer is made of a glass fiber material; the immunoadsorption layer comprises an anti-interference pad, the anti-interference pad is made of polyester fibers, and the anti-interference pad contains an anti-interference test; the sensitive layer comprises a cellulose acetate fiber pad membrane of which the outer surface is loaded with an antibody; the four-electrode system is composed of a working electrode, a reference electrode, a counter electrode and a contrast electrode, and the four-electrode system is formed by printing carbon paste or silver paste on the substrate. According to the electrochemical detection test strip with the structure, the anti-interference performance can be effectively improved, and the detection accuracy and precision are greatly improved.

The invention relates to the fields of therapy and drug delivery. It is based on an unexpected finding that a combination of an oligonucleotide-based medicament with a saponin component comprising a penta-cyclic triterpene saponin of a 12,13-dehydrooleanane aglycone core, not only does not appear to be associated with oligonucleotide medicament-induced nephrotoxic effects after systemic administration in vivo, but also that it allows the oligonucleotide-based medicament to enter and act on its nucleic acid target inside of the kidney cells instead of remaining unproductively trapped in renal subcellular compartments or being eliminated into the urine via the renal glomerular filtration system. In line with this finding, herein disclosed are therapeutic combinations, compositions, and formulations, as well as methods of treatment involving their administration, which comprise an oligonucleotide-based medicament that acts on an intracellular nucleic acid target in the kidney cells and / or in the cells of the spleen, being the other blood filtering organ in addition to the kidney, and a saponin component that enables the effective release of said medicament inside of these cells, thus allowing its use at a much lower and safer dose. The provision of the presented herein therapeutic combinations enables effective modulation of gene expression in the kidney and / or spleen cells and, therefore, it opens not only new treatment options for kidney diseases, in particular those involving inflammation and / or splenomegaly, but also for diseases of other organs which affect or are affected by the pathological processes happening in the kidneys and / or in the spleen, in particular being inflammatory processes.

The utility model relates to the technical field of thrombus filtering, and discloses a thrombus filtering device which comprises an equipment liquid inlet pipeline, an equipment liquid outlet pipeline and a thrombus filtering pipeline, a valve is further arranged at the liquid inlet of the equipment liquid inlet pipeline; the filtering assembly is used for filtering blood entering the thrombus filtering device; the equipment liquid outlet pipeline is used for conveying the filtered blood back to the living body; the driving mechanism is communicated with the equipment liquid inlet pipeline; in the blood filtering process, the driving mechanism generates negative pressure in the liquid inlet pipeline of the equipment so as to drive blood to flow through the opened valve and enter the filtering assembly to filter thrombus; in the blood conveying process, the driving mechanism generates positive pressure in the equipment liquid inlet pipeline, the valve is closed, and blood enters the equipment liquid outlet pipeline from the equipment liquid inlet pipeline and returns to the living body. By means of the structure, thrombus can be filtered, filtered blood drawn out of the body is re-infused into the body of a patient, and then the problem of blood waste is avoided.

An extracorporeal blood filtering machine can include a blood circuit, an effluent circuit, and a source fluid circuit and can be controlled by a controller. The extracorporeal blood filtering machine can also include access ports for connecting the source fluid circuit to the blood circuit, as well as blood sensors to detect possible issues with the extracorporeal blood filtering machine. The extracorporeal blood filtering machine can include density sensors and flow sensors that enable it to be more accurate and to operate while being transported. The extracorporeal blood filtering machine can further include a user interface and can display fluid inflow / outflow information. A medical fluid container can automatically empty after being filled. An apparatus for supporting a medical fluid container can include a hanger and an attachment member with the apparatus able to adjust to ensure the medical fluid container remains properly oriented directly under a medical fluid container scale.

A controller for controlling an apparatus comprising a blood pump, oxygenator, and blood filtering system connected together by blood flow tubing and to a patient to circulate blood from the patient through the apparatus and back to the patient, to oxygenate and filter the blood, the controller comprising at least one communication interface operable to receive signals generated responsive to monitored parameters characterizing blood flow and / or quality of blood from the patient circulating through the apparatus and configured to: determine values for the monitored parameters based on the monitoring signals; determine whether or not a value determined for a given monitored parameter for blood circulating through the apparatus is within a normative range for the parameter; and generate an alarm to alert an operator of the system if the value is not within the normative range.

The utility model discloses a live pig slaughtering suspension device, which relates to the technical field of livestock slaughtering and comprises a slaughtering table, a hydraulic cylinder is fixedly mounted on the slaughtering table, a supporting seat is fixedly mounted at the lifting end of the hydraulic cylinder, a hook is fixedly mounted at the bottom of the supporting seat, and a pig leg hanging mechanism for binding rear legs of a live pig is hung on the hook. A pig leg traction mechanism used for straightening front legs of live pigs is arranged on the slaughtering table, a pig blood collecting box is arranged on the slaughtering table, and a pig blood filtering mechanism used for filtering and discharging pig blood is arranged in the pig blood collecting box; according to the device, through the arrangement of the hydraulic cylinder, the pig leg tying and hanging mechanism, the pig leg traction mechanism, the pig blood collecting box, the pig blood filtering mechanism and other structures, the hydraulic cylinder can tighten the rear legs of a live pig and lift the live pig upwards, the bandage can straighten the front legs of the live pig to prevent the front legs of the live pig from kicking disorderly and injuring operators accidentally, and the filter screen can filter the collected pig blood; and the filtered pig blood is released through the release tube, so that the pig blood is convenient to collect.

The application discloses a blood sampling and detection card integrated device, relates to the technical field of blood sampling, and comprises a blood sampling needle and a detection card main body. One end of the blood sampling needle is provided with a hose, and one end of the hose is provided with a vacuum blood storage tube. A serum treatment tube is arranged at the bottom of the vacuum blood storage tube. A connecting assembly for quickly guiding blood is arranged between the vacuum blood storage tube and the serum treatment tube, and the connecting assembly comprises an inner clamping groove and an outer clamping plate. The outer clamping plate is slidably arranged in the inner clamping groove. The blood sampling and detection card integrated device can prevent blood coagulation through the anticoagulant in the built-in groove of the vacuum blood storage tube. The blood filtering film gasket treated by the anti-red blood cell antibody in the serum treatment tube can effectively filter red blood cells, obtain pure serum, avoid red blood cell interference on the detection result, and prevent blood or serum leakage and reduce the risk of cross contamination in the initial state through the close combination of the sealing gasket plate and the built-in groove and the sealing design of the aluminum foil.

The invention discloses a continuous protein rapid detection test strip and a preparation method thereof, the adopted technology is an immunochromatography method, and the reaction principle is a competition method. The test strip comprises a bottom plate, and a blood filter pad, a conjugate pad 1, a conjugate pad 2, a nitrocellulose membrane and a water absorption pad which are arranged on the bottom plate, the blood filtering pad is prepared after being treated by the pretreatment liquid; the conjugate pad 1 is coated with a zonulin polyclonal antibody marked by fluorescent microspheres and a chicken IgY antibody marked by fluorescence; the conjugate pad (2) is coated with a biotinylated zonulin antigen; the nitrocellulose membrane is provided with a detection line and a quality control line, and the detection line is coated with an anti-biotin antibody; and the quality control line is coated with a rabbit anti-chicken IgY antibody. According to the invention, not only can whole blood, serum and plasma samples be directly and rapidly detected, but also an excrement sample can be detected, the structure is simple, small and portable, and a simpler, more convenient and faster method is provided for rapid detection and screening of zonulin.

The invention belongs to the technical field of nephrology department, and particularly relates to a kidney perfusate constant-temperature conveying device which comprises a constant-temperature mechanism, a perfusate mechanism, a pressurizing conveying mechanism, the constant-temperature mechanism, a constant-temperature heating and maintaining preset range, the perfusate mechanism and an inflowing patient fistulization opening. The device is composed of a disposable blood filtering box, a modular assembly base, a constant temperature mechanism, a plurality of warm core rods and branch pipes used for supplying blood, the disposable blood filtering box is installed on the side of the surface of the modular assembly base, and the warm core rods are sequentially arranged in an arc-shaped groove of the disposable blood filtering box in a surrounding and clamping mode. By adopting the perfusion mechanism, blood can be extracted, and purified blood can be extracted.

A system and method for preparing a cancer vaccine (and optionally purifying blood) comprises a hemofiltration system controlled by a control unit for filtering exogenous plasma to isolate tumor cells, tumor stem cells, and tumor degradation products. The hemofiltration system filter may include multiple layers with openings of different sizes to hold substances of different sizes (from among tumor cells, tumor stem cells, and tumor degradation products of different sizes). The apparatus directs electromagnetic radiation to the isolated tumor cells, tumor stem cells, and / or tumor degradation products, which can cause a coagulated outer layer by degrading the outer surface of the isolated tumor cells, isolated tumor stem cells, and / or isolated tumor degradation products (e.g., tumor proteins such as DNA and / or tumor exosomes). The electromagnetic radiation may have a UV wavelength. A conical coil improves flow uniformity. Tumor exosomes can be centrifuged.

The invention provides a blood bag exhaust device and a blood filter, the blood bag exhaust device comprises a mounting seat, and the mounting seat is provided with a first peristaltic mechanism and a second peristaltic mechanism. The first wriggling mechanism is provided with a first pipe groove and a first extrusion assembly, and the first extrusion assembly can stretch into the first pipe groove to extrude the bypass hose and retreat from the first pipe groove to release the bypass hose. The second wriggling mechanism is provided with a second pipe groove and a second extrusion assembly, and the second extrusion assembly can stretch into the second pipe groove to extrude the filtering hose and retreat from the second pipe groove to release the filtering hose. The driving module is electrically connected with the control module, is in driving connection with the first extrusion assembly and the second extrusion assembly and is used for driving the first extrusion assembly to extrude / release the bypass hose and driving the second extrusion assembly to extrude / release the filter hose. Automatic filtering, exhausting and blood sample reserving are achieved, and the problems that time and labor are consumed and efficiency is low due to manual control over a check valve, exhausting and blood sample reserving are effectively solved.

The utility model relates to the technical field of blood filtering and collecting devices, in particular to a blood filtering and collecting device of a cattle and sheep blood drawing operation table, which comprises a support, a filtering piece is fixed on the surface of the support through a fixing piece in a butt joint mode, the filtering piece comprises a puncture needle, and the bottom end of the puncture needle is connected with a drainage tube. The tail end of the drainage pipe is in butt joint with a polyethersulfone membrane filter, the bottom end of the polyethersulfone membrane filter is in butt joint with a hopper cover, the hopper cover is buckled on the surface of a hopper, the bottom end of the hopper is in butt joint with a collecting bag, and a speed adjusting part is arranged at the pipeline end of the polyethersulfone membrane filter. According to the utility model, by pressing the scale strip, the scale strip is controlled to push the pressing plate, so that the pressing plate applies pressure to the pipeline surface of the polyethersulfone membrane filter, and the flow velocity of blood in the pipeline of the polyethersulfone membrane filter is adjusted and changed; therefore, the filtering effect of the polyethersulfone membrane filter is ensured, the filter is prevented from being blocked, blood components are protected, the detection accuracy is ensured, and the detection efficiency is improved to a certain extent.

The utility model discloses a sub-bag lifting device which is provided with a machine frame, a bag body supporting frame and a lifting driving unit, the bag body supporting frame is connected to the machine frame in a sliding mode through a guide rod, a collecting bag can be placed on the bag body supporting frame and can be supported by the bag body supporting frame, and the lifting driving unit is connected with the bag body supporting frame. The bag body supporting frame can be driven to slide, so that the height of the bag body supporting frame is adjusted, the white blood filtering system is provided with the structure, when the white blood filtering work is carried out, after a collecting bag is placed on the bag body supporting frame, the lifting driving unit drives the bag body supporting frame to descend, and the terrain of the collecting bag on the bag body supporting frame is lowered; and the distance between the collecting bag and the blood bag is increased, so that the blood conveying speed is increased, and the white blood filtering efficiency of the blood is improved.