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205 results about "Sample dilution" patented technology

Intelligent microbiological detection pretreatment workstation

The invention discloses an intelligent pretreatment workstation for microbiological detection, and relates to the technical field of microbiological detection. The module comprises a culture dish turntable, a transmission part, a homogeneous slapping part, a vortex oscillation part, a material rack storage part, a culture medium feeding part and the like; the culture dish turntable module comprises an upper dish station, a liquid injection station, an inoculation / coating station, a lower dish station and the like, as well as a transplanting electric module and a shaking-up module; the liquid injection unit can be used for injecting three culture solutions; the culture dish conveying module is responsible for conveying culture dishes to corresponding stations and is connected with an external feeding and receiving unit; the material rack storage module is used for storing pipettor tips, test tubes and homogenizing bags; the homogeneous slapping and vortex oscillation module is used for sample dilution and homogenization; the clamping robot is responsible for conveying the homogeneous bag and the test tube to the corresponding module and pulling out the plug of the test tube; the pipetting robot is used for sucking a sample and filling the sample into the culture dish. The steps from sample to culture can be completed at high speed and high efficiency, and the steps can be adjusted according to actual detection conditions through modular combination.
Owner:ZUNCE TECHNOLOGY (SUZHOU) CO LTD

Kit for rapidly detecting hiPSC residues in hiPSC derived cells and application of kit

The invention belongs to the technical field of biomedicine, and relates to a kit for rapidly detecting hiPSC residues in hiPSC derived cells and application of the kit. The kit comprises six components, namely an NANOG gene primer probe composition, a TaqMan Fast qPCR (Polymerase Chain Reaction) premixed solution, a standard quality particle, a positive reference substance, a sensitivity reference substance and a sample dilution buffer solution, according to the kit, the NANOG gene sequence serves as a template, the designed primer pair and probe have high specificity, absolute quantitative detection can be conducted on hiPSC residues in an intermediate product, a semi-finished product and a finished product (obtained through differentiation of an endoderm, a mesoderm and an ectoderm) of a human induced pluripotent stem cell derived cell preparation, and compared with other detection modes such as a culture method, the detection method has the advantages that the detection efficiency is high, and the detection cost is low. False positive results caused by a detection method are avoided, and the method has the detection characteristics of simplicity and rapidness in operation, high specificity and high sensitivity.
Owner:SHAANXI JIUZHOU CELL GENETIC ENG CO LTD

Automatic sampling and pretreatment system for trace water-soluble metal elements in atmosphere

The invention discloses an atmospheric trace water-soluble metal element automatic sampling and pretreatment system, the system comprises an automatic sampling module and a pretreatment module, the automatic sampling module is provided with a gas introduction device, a gas corrosion device and a mixing growth chamber from front to back in sequence, and the mixing growth chamber is connected with the pretreatment module; the gas corrosion device is used for separating particulate matters and gas in a to-be-collected atmospheric sample, and the mixed growth chamber enables the particulate matters to grow and condense in supersaturated water vapor to obtain a primary sample; the pretreatment module comprises a sample enrichment unit and an automatic calibration unit; the sample enrichment unit is used for carrying out enrichment treatment on the primary sample through a bubble remover and a plastic injector; the automatic calibration unit is used for sequentially carrying out acid pickling, water washing, sample dilution and quantitative calibration on the enriched sample to finish the pretreatment process of the sample; according to the system, the sampling efficiency and the data reliability are remarkably improved, the automation degree is high, manual operation is reduced, personal errors are reduced, and the monitoring efficiency is improved.
Owner:INST OF ATMOSPHERIC PHYSICS CHINESE ACADEMY SCI

Preparation method of CGRP detection kit and application of CGRP detection kit in migraine diagnosis

The invention discloses a preparation method of a CGRP detection kit and application of the CGRP detection kit in migraine diagnosis, and belongs to the technical field of biological medicine detection. According to the invention, alpha-CGRP polypeptide coupled KLH protein is subjected to efficient animal immunization, an antibody with good affinity is screened by using methods such as enzyme-linked immunosorbent assay, cross pairing analysis is carried out, and final antibody sequence information is obtained through sequencing. The paired monoclonal antibody screened by the invention has high sensitivity (KD value of 1nM), the limit of detection (LoD) can be as low as pg / mL level, a low-concentration CGRP sample can be effectively detected, the matrix effect of human serum / plasma can be effectively neutralized by an optimized sample diluent formula, and the repeatability is high (in-plate and inter-plate CV values of 1t and 10%). According to the invention, the kit prepared from the specific paired antibody is systematically and closely linked with the indication function of migraine for the first time, and a clinical diagnosis direction is provided.
Owner:JIANGSU MEDOMICS MEDICAL TECHNOLOGY CO LTD

Flowing type full-automatic biological particle quantitative detection treatment method and device

PendingCN119413691Arapid dilutionrapid concentrationPreparing sample for investigationIndividual particle analysisCellStorage area
The invention discloses a flowing type full-automatic biological particle quantitative detection processing method and device, which are characterized in that detection signals are collected, processed and analyzed in real time, the concentration of a detected substance in a sample is calculated, and the dilution process is controlled, so that the accuracy and reliability of a detection result are ensured; through automatic concentration adjustment, real-time monitoring, calculation and automatic dilution of the sample concentration are realized, and the sample concentration is ensured to be adjusted to a reasonable range required by detection; the flowing of a sample and a diluent among a sample storage area, a sample dilution area, a diluent storage area, a sample detection area and a subsequent processing module is realized through a sample feeding module, and the high efficiency and continuity of a detection process are ensured through an integrated design; after the concentration of the sample reaches the standard, the sample can be subjected to follow-up treatment, such as sorting and separation, so that fine treatment of the sample is realized; the detection can cover a variety of biological particles, including nanoparticles, cells, extracellular vesicles, bacteria, viruses and the like, and has a wide application range.
Owner:杭州芮一生物科技有限公司

Colloidal gold immunochromatographic test strip for detecting enramycin, preparation method, and application thereof

The invention provides a colloidal gold immunochromatographic test strip for detecting enramycin, a preparation method, and an application thereof, which belongs to the field of rapid immunoassay; the test strip comprises a backing plate, a sample pad, a conjugate pad, a nitrocellulose membrane, and an absorbent pad; the conjugate pad was fixed with colloidal gold-labeled enramycin monoclonal antibody; the nitrocellulose membrane is equipped with a T-line coated with enramycin artificial antigens and a C-line coated with goat anti-mouse secondary antibodies. The invention also provides a kit for detecting enramycin, comprising a test strip, a sample treatment solution, and a sample diluent. The invention further adds a test strip shooting background board to the kit, which can be used for rapid qualitative or quantitative detection of enramycin in animal feed and products of animal meat and egg with a detection limit of 10 mg / k
Owner:ZHEJIANG GONGSHANG UNIVERSITY +1

Automatic sample diluting device

The utility model discloses an automatic sample diluting device which comprises a sampling mechanism and a cleaning mechanism, the cleaning mechanism comprises a cleaning sleeve, and the side part of the cleaning sleeve is communicated with a cleaning introduction pipe and a cleaning discharge pipe; a sampling arm of the sampling mechanism is driven by a ball screw nut pair driven by a stepping motor I to ascend and descend along a left linear guide pair and a right linear guide pair, the overhanging end of the sampling arm is provided with a double-cavity needle tube sampling needle which downwards penetrates through a cleaning sleeve and is aligned to a sampling test tube, and at the top of the sampling needle, one cavity tube is connected with the sampling tube, and the other cavity tube is connected with a sampling test tube; at the descending limiting position of the sampling arm, the sampling needle extends into the sampling test tube and the needle tip at the lower end of the sampling needle does not touch the bottom of the sampling test tube, and at the ascending limiting position of the sampling arm, the sampling needle retreats from the sampling test tube and the needle tip of the sampling needle is located in the cleaning sleeve. According to the utility model, the instrument detection efficiency is improved, sampling consumables are saved, and the defect of sample pollution caused by difficulty in complete manual cleaning is overcome.
Owner:CHINA NONFERROUS METALS (GUILIN) GEOLOGY AND MINING CO LTD

Sample processing and scheduling system and control method

The invention relates to the technical field of sample processing, and relates to a sample processing and scheduling system and a control method, and the method comprises the steps: controlling a reaction disc assembly to rotate according to a rotation period, and controlling the reaction disc assembly to progressively preset the number of cups in each rotation period; wherein the rotation period comprises a plurality of rotation stages; the duration of the rotation period and the interval duration of the plurality of rotation stages are determined according to the target reaction system; determining a target dilution cup and a target reaction cup in the reaction disc assembly according to the first target rotation period, the number of preset cup positions and the total number of cup positions in the reaction disc assembly; according to the target rotation period of the actions corresponding to sample, reagent, diluent and sample dilution in the sample processing task, the sampling needle assembly and the reagent needle assembly are controlled to execute the corresponding actions on the target dilution cup and the target reaction cup respectively, so that the sample processing task is completed. Therefore, the problems of low sample processing speed and high cost can be effectively solved.
Owner:SHENZHEN LIFOTRONIC TECH

Chromatography methods

Disclosed herein are improved methods for quantifying monoclonal antibody (mAb) titer using Protein A affinity High-Performance Liquid Chromatography (HPLC). The methods address inaccuracies caused by mAb adsorption to sample vial surfaces by incorporating a surfactant into the mobile phase used for sample dilution. This approach enhances the accuracy, linearity, and robustness of the titer assay, making it suitable for process control and quality assessment in biopharmaceutical development and manufacturing. The methods can be applied as a platform approach for various mAb products.
Owner:R P SCHERER TECH INC

Sampling needle cleaning system

The utility model relates to a sampling needle cleaning system. The sampling needle cleaning system comprises a gush type cleaning pool, a cleaning liquid conveying unit and a blow-drying unit, the gush type cleaning pool is used for containing a sampling needle capable of moving up and down relative to the gush type cleaning pool, and the cleaning liquid conveying unit is communicated with the gush type cleaning pool and used for conveying cleaning liquid to the gush type cleaning pool; the blow-drying unit is communicated with the gushing type cleaning pool, and the blow-drying unit is used for conveying gas to the gushing type cleaning pool. Through the arrangement, after the sampling needle leaves the cleaning liquid level after being cleaned, the blow-drying unit can blow the outer surface of the sampling needle and blow off hanging liquid on the outer surface of the sampling needle, so that the hanging liquid on the surface of the sampling needle is prevented from entering a next to-be-detected sample along with the sampling needle to cause sample dilution, and the accuracy of a detection result is improved.
Owner:江苏三联生物工程股份有限公司

Medical diagnostic analyzers for nursing points, and apparatus, systems and methods for performing medical diagnostic analysis on samples.

PendingCN122306665APoint of careNursing care
An analyzer having an inner chassis surrounded by a housing includes: sample and diluent probes, a mixing housing including a first mixing chamber and a second mixing chamber, a flow cytometer including a flow unit, and sample and sheath pumps configured to perform a first set of tasks and a second set of tasks, respectively. The first set of tasks includes: aspirating a sample into the sample probe; dispensing a sample from the sample probe into the first and second mixing chambers; delivering a first sample diluent mixture to the flow unit; and delivering a second sample diluent mixture to the flow unit. The second set of tasks includes: dispensing a sheath into the flow unit in a manner cooperating with delivering the first sample diluent mixture to the flow unit; and dispensing a sheath into the flow unit in a manner cooperating with delivering the second sample diluent mixture to the flow unit.
Owner:IDEXX LABORATORIES INC

Sample sampling and detecting device

The invention belongs to the technical field of instant diagnosis, and particularly relates to a sample sampling and detecting device. The sample sampling and detecting device comprises a sample diluting assembly and a sampling assembly, the sample dilution assembly comprises a sample dilution box, and the sample dilution box is provided with a containing cavity for storing sample dilution liquid; the sampling assembly comprises a sampling head, detection test paper and a flow guide structure, the sampling head is provided with a liquid inlet, the sampling head can be inserted into the accommodating cavity so that a sample diluent enters the sampling head through the liquid inlet and is mixed with a sample, and the flow guide structure is arranged in the sampling head and is provided with a flow guide part; a lateral flow channel is formed between the flow guide part and the inner wall of the sampling head. By using the sample sampling and detecting device in the technical scheme, a sample diluent can be prevented from overflowing from a gap between the outer wall of the sampling head and the inner wall of the sample dilution box in the process that the sampling head is inserted into the sample dilution box, meanwhile, waste caused by splashing of the sample diluent can be prevented, and full contact of the sample diluent and detection test paper is ensured.
Owner:SHENZHEN YHLO BIOTECH

Hydrogen Peroxide Rapid Test Kit and Method of Use

The present invention discloses a rapid hydrogen peroxide test kit and a method of using the same, the rapid hydrogen peroxide test kit comprising a sample diluent and a test strip containing a chromogen for detection and a chromogen for quality control in a dry environment. The sample diluent comprises 100-500 mM ammonium oxalate, 0.3-2.0 mM 8-hydroxyquinoline, 50-500 mM sodium chloride, and 10-100 mM of a first pH adjuster for pH 4.5-7.0.
Owner:ZHEJIANG JFK BIOLOGICAL TECH

A kit for detecting anti-peroxiredoxin-1-igG antibody

This invention provides a kit for detecting anti-peroxidase-1-IgG antibodies, comprising the antigen protein peroxiredoxin-1 (peroxidase-1), a solid-phase carrier, labeled antibody, antigen dilution buffer, sample dilution buffer, antibody dilution buffer, substrate chromogenic agent, washing buffer, standards, positive control, and negative control. This kit utilizes an indirect reaction principle combined with magnetic microparticle chemiluminescence immunoassay to detect anti-peroxidase-1-IgG antibodies in the serum of the test sample. This invention is the first to identify autoantibodies against the target antigen peroxidase-1 in the serum of patients with autoimmune nephrotic syndrome. The provided kit provides a basis for domestic and international research on the molecular mechanisms and clinical diagnosis and treatment of autoimmune nephrotic syndrome related to peroxidase-1 and peroxidase-1-IgG autoantibodies.
Owner:ZHEJIANG UNIV

A kit for detecting antigen myosin 1-IgG antibody

The present invention provides a kit for detecting antigen myosin 1 IgG antibodies, which is composed of antigen protein Tropomyosin 1 (tropomyosin 1), a solid phase carrier, a standard, a positive quality control product, a negative quality control product, a labeled antibody, a substrate color developing solution, an antibody diluent, an antigen diluent, a sample dilution buffer, a washing solution, a stop solution, etc. The present invention utilizes the target antigen Tropomyosin 1 corresponding to the anti-Tropomyosin 1 IgG antibody, and uses human anti-label peptide IgG as a standard for quantitative detection to perform anti-Tropomyosin 1 IgG antibody detection on the antigen-antibody complex formed in the serum. The kit of the present invention is easy to operate, has very good reagent stability, is easy to store, and fills the gap in identifying biomarkers for patients with immune nephrotic syndrome at home and abroad.
Owner:ZHEJIANG UNIV

Multi-index quantitative detection reagent card for vasculitis

ActiveCN223180219UMaterial analysisVascular inflammationVasculitis
The reagent card comprises a shell and a test strip, a sample adding groove and a test window are formed in the shell at intervals, the sample adding groove sequentially comprises an upper cover, a uniform mixing bin and a blood filtering film from top to bottom, a sample adding hole is formed in the middle of the uniform mixing bin, and the test strip is arranged in the sample adding hole. The upper cover covers the upper end face of the uniform mixing bin in an openable and closable manner to shield the sample adding hole, a first film is arranged on the bottom surface of the sample adding hole, a second film is arranged on the bottom surface of the uniform mixing bin, the second film is positioned below the first film, and a sample diluent is filled between the second film and the first film, the blood filtering film is arranged below the second film, and a sampling needle is arranged on the bottom surface of the upper cover. And a pressing part which can be pressed to deform is arranged on the upper cover corresponding to the sampling needle. Due to the design of the sample adding groove, the applicability of a scene is improved, and a sample dilution step is omitted. The advantages of the four detection indexes complement each other, the operation is simple and rapid, the cost is low, the result is accurate, the sensitivity is high, the specificity is high, and the accuracy of vascular inflammation detection can be effectively improved.
Owner:SUZHOU KUIKTAI BIOTECHNOLOGY CO LTD

Biological sample diluting and cultivating device

The utility model discloses a biological sample dilution cultivation device which comprises an upper cover, a stress strip is fixedly installed on the outer side of the upper cover, a sealing strip is fixedly installed on the circumferential inner wall of the upper cover, meanwhile, a cultivation vessel is installed at the bottom of the upper cover, a positioning area is arranged on the outer side of the cultivation vessel, and a first blocking piece is fixedly arranged in the cultivation vessel. A second blocking piece is installed on one side of the first blocking piece, and meanwhile a third blocking piece is installed on one side of the second blocking piece. According to the biological sample diluting and cultivating device, biological samples needing to be cultivated are evenly divided into four groups to be sequentially placed into the first cultivating tank, the second cultivating tank, the third cultivating tank and the fourth cultivating tank, and during diluting, the samples in the four groups of cultivating tanks can be diluted in a grouping mode; the content of each group of samples needing to be diluted is reduced, and the sample dilution uniformity is improved; the device can be used for observing the growth conditions of samples under different dilution concentrations.
Owner:SHANGHAI FUTURE IND CO LTD

Kit and method for detecting concentration of Venoclarias

The invention provides a kit for detecting the concentration of Venoclarias and a Venoclarias concentration detection method, and belongs to the technical field of in-vitro diagnos.The kit comprises a calibrator, an internal standard mother solution, a quality control product, an internal standard-sample releasing agent, a sample dilution treating fluid and a mobile phase. And the detection of low-concentration Venokacrah can be realized. The kit provided by the invention also has the advantages of high sensitivity, strong anti-interference capability and high accuracy.
Owner:THE SECOND AFFILIATED HOSPITAL TO NANCHANG UNIV

A sample diluent and its preparation method

PendingCN122283115ASample dilutionBiochemistry
This disclosure relates to a sample diluent and its preparation method. Specifically, this disclosure relates to a sample diluent composed of Tris, Tween-20, BSA, mixed serum, and PC300. A key improvement is that the mixed serum is prepared by mixing goat serum and fetal bovine serum at a volume ratio of 2:1, and the mixed serum accounts for 40% of the sample diluent. The sample diluent of this disclosure is designed for the detection of lambda and kappa type free light chains, significantly reducing sample matrix interference, improving detection specificity and stability, and solving the technical problem of disproportionate dilution after high-value sample dilution. It is suitable for clinical testing, biomedical research, and other scenarios.
Owner:BEIJING STRONG BIOTECH INC

Sample ion detection method and sample dilution method

The invention provides a sample ion detection method and a sample dilution method, and belongs to the technical field of trace detection. Comprising the following steps: acquiring the conductivity of a to-be-tested sample, substituting the conductivity into a preset dilution relation function, and obtaining the dilution multiple of the to-be-tested sample by utilizing the dilution relation function; diluting the to-be-tested sample according to the dilution ratio to obtain a diluted sample; and testing the diluted sample to obtain the ion concentration. Therefore, after the to-be-tested sample is taken, the accurate dilution multiple can be obtained only by measuring the conductivity of the to-be-tested sample and substituting the conductivity into the dilution relation function, and the sample is diluted and tested, so that accurate dilution and test of different samples are realized, namely, the different to-be-tested samples are adaptively diluted and tested by adopting the appropriate dilution multiple; therefore, the test data is more accurate, and the test efficiency is higher.
Owner:LANZHOU UNIV

Biological sample diluent and application of detection method thereof in immunodetection kit

The invention belongs to the technical field of biological detection, and particularly relates to application of a biological sample diluent and a detection method thereof in an immunodetection kit. The biological sample diluent is prepared from 6.055 g / L of tris (hydroxymethyl) aminomethane, 35 g / L of sodium chloride, 0.6 mL / L of triton X-100, 0.6 g / L of a surfactant S-9, 1 g / L of bovine serum albumin and 0.2 mL / L of a liquid biological preservative. The surfactant S-9 and the triton X-100 in the biological sample diluent have a synergistic effect under a specific concentration, so that the foaming phenomenon is effectively improved, meanwhile, the biological sample diluent also has high elution and dissolution rate on target protein, and the accuracy of immunodetection is improved.
Owner:BEIJING NO 1 BIO-TECH DEV CO LTD

An isolation and culture method of Megasphaera elsdenii in the intestine and its application

ActiveCN115851518BBacteriaAnimal feeding stuffMegasphaera elsdeniiIn vivo
The invention discloses a method for isolating and culturing Megasphaera elsdenii in the intestine and its application, belonging to the technical field of microbiology. The Megasphaera elsdenii (Megasphaera elsdenii) pSML provided by the invention was deposited at the Guangdong Provincial Microbial Culture Collection Center on October 19, 2022, and the deposit number is: GDMCC No: 62902. The method for isolating and culturing the Megasphaera elsdenii includes the following steps: S1 preparing a fecal suspension; S2 enrichment culture; S3 preparing a sample dilution; S4 strain screening; S5 isolation and purification culture; S6 in vitro fermentation. The invention uses human feces and performs enrichment culture before isolation and purification, which increases the proportion of the target bacteria in the screening process, reduces the isolation difficulty and improves the isolation efficiency. By using this bacterium for in vitro fermentation, it is found that it can utilize prebiotics to produce glutathione and has the potential to improve in vivo oxidative stress, providing new ideas for the future development and utilization of this bacterium.
Owner:JIANGNAN UNIV

Biological reaction chip, biological reaction equipment and biological detection method

The invention discloses a biological reaction chip, biological reaction equipment and a biological detection method.The biological reaction chip comprises a chip body and a sealing layer, the chip body is provided with a material cavity, and the material cavity is provided with a ventilation structure; the material chamber comprises a sample containing area, a diluent sample adding area, a sample diluting and mixing area, a pre-reaction area and a reaction detection area, a detection sample entering the sample containing area from the first sample adding port and a diluent entering the diluent sample adding area from the second sample adding port can enter the sample diluting and mixing area to be mixed, and then the mixed liquid enters the pre-reaction area; reacting with a first reaction substance in the pre-reaction area to form pre-reaction liquid, and enabling the reaction liquid to enter the reaction detection area to react with a second reaction substance to form a test sample. According to the biological reaction chip provided by the invention, the labor intensity of workers during detection is effectively reduced.
Owner:BOAO BIOLOGICAL CO LTD +1

Sample diluting device for inspection

The utility model relates to the technical field of sample diluting equipment, in particular to a sample diluting device for inspection, which comprises a main body, the main body comprises a top cover and a diluting barrel, the top surface of the top cover is provided with a sample inlet hole and a diluent hole, a liquid inlet hopper is fixedly inserted into the inner wall of the sample inlet hole, a liquid inlet pipe is fixedly inserted into the inner wall of the diluent hole, and a liquid outlet pipe is fixedly inserted into the liquid inlet pipe. The top end of the liquid inlet pipe communicates with a diluent container, a first electromagnetic valve is fixedly connected to the outer wall of the liquid inlet pipe in a sleeving mode, a double-shaft motor is fixedly connected to the interior of the top cover, and a first motor shaft of the double-shaft motor is in transmission connection with a first gear. According to the device disclosed by the utility model, the top cover, the diluent container, the double-shaft motor, the stirring unit, the diluting barrel, the gear I, the electric telescopic rod, the one-way bearing, the gear II, the turntable, the plurality of sample containers and the electromagnetic valve II are arranged in a matched manner, so that the device can be used for automatically stirring and diluting by driving the double-shaft motor; and an operator does not need to repeatedly add or replace the sample container, so that the working efficiency is improved.
Owner:彭兵

AAV neutralizing antibody detection method

The invention discloses a method for detecting an AAV neutralizing antibody. The method comprises the following steps: preparing a recombinant AAV vector AAV-Gluc carrying a Gaussian luciferase reporter gene; the method comprises the following steps: diluting AAV-Gluc according to a certain dilution step to prepare an AAV-Gluc working solution; diluting the sample to be detected; carrying out cell planking, culturing the target cells to form a uniform cell suspension, and adding the cell suspension into a cell culture plate; mixing the sample diluent with the AAV-Gluc diluent, and carrying out incubation; adding the incubated sample mixed solution into the cell culture plate, and carrying out virus infection and culture; obtaining a cultured cell supernatant, adding a detection solution, and detecting signal intensity; and analyzing and sorting the data to obtain the neutralization titer. The secreting type Gaussian luciferase reporter vector is used, target protein is secreted outside cells after being expressed, and detection is facilitated; the infected supernatant is directly sucked for detection, and the operation is convenient and fast; cell lysis and extraction are not needed, protein loss is reduced, and detection accuracy and precision are improved.
Owner:NIKETHERAPEUTICS (HANGZHOU) CO LTD

Automatic uniform mixing equipment for blood sampling

The invention relates to the technical field of sample dilution, dispersion or mixing, and discloses blood sampling automatic uniform mixing equipment which comprises a conveying line, a blood sample placing mechanism mounted on the conveying line and a uniform mixing area located on one side of the conveying line. The blood sample placing mechanism comprises a fixing block and a floating blood sampling frame, the fixing block is fixed to the conveying surface of the conveying line, the floating blood sampling frame is vertically and slidably connected with the fixing block, and an elastic reset piece is arranged on the floating blood sampling frame; protrusions are arranged on the uniform mixing area at intervals, and rolling pieces capable of making contact with the protrusions are arranged at the bottom of the floating blood sampling frame. The problem that the overall efficiency is low due to the fact that an existing blood sampling and mixing process depends on medical staff is solved.
Owner:THE FIRST AFFILIATED HOSPITAL OF ARMY MEDICAL UNIV

Instrument range intelligent expansion optimization method based on sample dilution

The invention relates to the technical field of instrument measuring range expansion, in particular to an instrument measuring range intelligent expansion optimization method based on sample dilution, which comprises the following steps: acquiring an effective measuring range threshold value through an intelligent sensor, counting relative standard deviation and signal-to-noise ratio of a concentration interval in the measuring range, and acquiring a precision distribution curve; performing original sample test on a to-be-tested sample, directly detecting if a response value is within a range, starting an intelligent prediction model according to pollutant types and matched dilution parameters of the to-be-tested sample if the response value exceeds the range, and predicting a recommended dilution multiple according to initial test signal intensity and the sample; when the prediction confidence is lower than a threshold value, triggering gradient scanning; carrying out parallel sample measurement on the diluent to calculate relative standard deviation, executing two adjacent dilution multiples if the distance difference between the diluent and the segmented boundary is smaller than a threshold value, and carrying out mutual verification through concentration consistency of an overlapping region; and performing full-process detection on different dilution multiples, establishing a dilution correction model, updating a correction coefficient of the dilution multiples, and updating a range boundary and a precision distribution curve.
Owner:NANJING HUATIAN SCI & TECH DEV CO LTD +1

Specific protein analyzer sample track sample injection step circulation dilution reexamination method

The invention relates to a specific protein analyzer sample track sample injection step cycle dilution reexamination method. The method comprises the following steps: 1, sucking a sample to be detected, and respectively adding the sample to be detected into a reaction cup and a dilution cup; 3, judging whether the analyzer outputs an effective detection result or not, if yes, executing the step 6, and if not, executing the step 4; 4, the dilution puncture needle sucks the sample diluent and the to-be-detected sample in the dilution cup and distributes the sample diluent and the to-be-detected sample in the dilution cup to the dilution cup in an idle state for dilution, and the diluted to-be-detected sample is obtained; 5, sucking the diluted to-be-detected sample into the idle reaction cup by the sample adding needle, and executing the step 2; 6, emptying and cleaning the reaction cup and the dilution cup corresponding to the to-be-detected sample, according to the scheme, the dilution and re-detection process of the sample does not need to be manually intervened, when the detection result is not output, the sample can be automatically diluted and re-detected through the dilution puncture needle and the sample adding needle, the re-detection time is greatly shortened, and the detection efficiency is improved.
Owner:PINFENG (CHONGQING) MEDICAL EQUIPMENT CO LTD

A direct bilirubin assay kit and its usage method

This invention discloses a direct bilirubin assay kit and its usage method. The kit includes reagent A, reagent B, and reagent C. Reagent A contains sulfuric acid; reagent B contains 2,5-diethoxy-4-(4-morpholino)diazobenzene sulfate and sulfuric acid; and reagent C contains N,N-diisopropylethylamine and n-hexane. Using this kit, the upper limit of linearity reaches 500 μmol / L, making it suitable for the determination of higher concentrations of direct bilirubin. When measuring high-concentration samples, sample dilution is not required, reducing operational steps and minimizing the influence of human factors on the results. This kit shows no significant interference in DBIL determination when hemoglobin concentration is ≤4.5 g / L, and no significant interference in DBIL determination when triglyceride concentration is ≤40 mmol / L (P>0.05). This indicates that the kit is more suitable for the detection of lipemia and hemolyzed samples.
Owner:HAINAN DIAN MEDICAL LAB CO LTD

Multifunctional kit

The utility model relates to the technical field of experimental tools, in particular to a multifunctional kit which comprises a kit body and a kit cover, a clamping support is arranged in the kit body, a plurality of clamping grooves used for clamping and storing reagents are formed in the clamping support, an auxiliary chuck is detachably assembled at an opening of the kit body, and a plurality of clamping holes are formed in the auxiliary chuck in an array mode. The clamping hole is used for keeping the tubular container in a vertical state, the tubular container comprises an EP tube and / or a cryopreservation tube, the box cover is detachably assembled on the peripheral edge of the auxiliary chuck, and the auxiliary chuck and the clamping support are arranged in parallel in a vertically spaced mode. According to the multifunctional kit, a worker can vertically insert an EP tube, a cryopreservation tube and other tubular tools into the clamping holes, reagents / samples in the tube can be conveniently stored or taken, during detection, the worker does not need to additionally prepare an EP tube frame or a sample tube frame or other experiment tools, standard substance preparation, sample dilution and other operations can be directly carried out, operation is more convenient and faster, and the working efficiency is improved. The detection efficiency is improved, and the experiment cost is reduced.
Owner:WUHAN CLOUD CLONE CORP